LOCUS       NM_134406               4198 bp    mRNA    linear   ROD 10-FEB-2025
DEFINITION  Rattus norvegicus phosphofurin acidic cluster sorting protein 1
            (Pacs1), mRNA.
ACCESSION   NM_134406
VERSION     NM_134406.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 4198)
  AUTHORS   Kottgen,M., Benzing,T., Simmen,T., Tauber,R., Buchholz,B.,
            Feliciangeli,S., Huber,T.B., Schermer,B., Kramer-Zucker,A.,
            Hopker,K., Simmen,K.C., Tschucke,C.C., Sandford,R., Kim,E.,
            Thomas,G. and Walz,G.
  TITLE     Trafficking of TRPP2 by PACS proteins represents a novel mechanism
            of ion channel regulation
  JOURNAL   EMBO J 24 (4), 705-716 (2005)
   PUBMED   15692563
REFERENCE   2  (bases 1 to 4198)
  AUTHORS   Huang,Z., Philippin,B., O'Leary,E., Bonventre,J.V., Kriz,W. and
            Witzgall,R.
  TITLE     Expression of the transcriptional repressor protein Kid-1 leads to
            the disintegration of the nucleolus
  JOURNAL   J Biol Chem 274 (12), 7640-7648 (1999)
   PUBMED   10075651
REFERENCE   3  (bases 1 to 4198)
  AUTHORS   Wan,L., Molloy,S.S., Thomas,L., Liu,G., Xiang,Y., Rybak,S.L. and
            Thomas,G.
  TITLE     PACS-1 defines a novel gene family of cytosolic sorting proteins
            required for trans-Golgi network localization
  JOURNAL   Cell 94 (2), 205-216 (1998)
   PUBMED   9695949
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AF076183.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AF076183.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760434 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..4198
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q43"
     gene            1..4198
                     /gene="Pacs1"
                     /gene_synonym="Pacs-1"
                     /note="phosphofurin acidic cluster sorting protein 1"
                     /db_xref="GeneID:171444"
                     /db_xref="RGD:620579"
     exon            1..450
                     /gene="Pacs1"
                     /gene_synonym="Pacs-1"
                     /inference="alignment:Splign:2.1.0"
     CDS             101..2986
                     /gene="Pacs1"
                     /gene_synonym="Pacs-1"
                     /note="cytosolic sorting protein PACS-1"
                     /codon_start=1
                     /product="phosphofurin acidic cluster sorting protein 1"
                     /protein_id="NP_599233.1"
                     /db_xref="GeneID:171444"
                     /db_xref="RGD:620579"
                     /translation="MAERGGAGGGPGGAGGGSSQRGSGVAQSPQQQPPQQPSQPQQPT
                     PPKLAQATSSSSSTSAAAASSSSSSTSTSMAVAVASGSAPPGGPGPGRTPAPVQMNLY
                     ATWEVDRSSSSCVPRLFSLTLKKLVMLKEMDKDLNSVVIAVKLQGSKRILRSNEIILP
                     ASGLVETELQLTFSLQYPHFLKRDANKLQIMLQRRKRYKNRTILGYKTLAVGLINMAE
                     VMQHPNEGALVLGLHSNVKDVSVPVAEIKIYSLSSQPIDHEGIKSKLSDRSPDIDNYS
                     EEEEESFSSEQEGSDDPLHGQDLFYEDEDLRKVKKTRRKLTSTSAITRQPNIKQKFVA
                     LLKRFKVSDEVGFGLEHVSREQIREVEEDLDELYDSLEMYNPSDSGPEMEETESILST
                     PKPKLKPFFEGMSQSSSQTEIGSLNSKGSLGKDTTSPMELAALEKVKSTWIKNQDDSL
                     TETDTLEITDQDMFGDASTSLVVPEKVKTPMKSSKADLQGSASPSKVEGTHTPRQKRS
                     TPLKERQLSKPLSERTNSSDSERSPDLGHSTQIPRKVVYDQLNQILVSDAALPENVIL
                     VNTTDWQGQYVAELLQDQRKPVVCTCSTVEVQAVLSALLTRIQRYCNCNSSMPRPVKV
                     AAVGSQSYLSSILRFFVKSLASKTPDWLGHMRFLIVPLGSHPVAKYLGSVDSRYSSTF
                     LDSAWRDLFSRSEPPVSEPLDVVGRVMQYVNGATTTHQLPVAEAMLTCRHKFPDEDSY
                     QKFIPFIGVVKVGLVEDSPSTAGDGDDSPVVSLTVPSTSPPSSSGLSRDATATPPSSP
                     SMSSALAIVGSPNSPYGDVIGLQVDYWLGHPGERRREGDKRDASSKNTLKSVFRSVQV
                     SRLPHAGEAQLSGTMAMTVVTKEKNKKVPTIFLSKKPREKEVDSKSQVIEGISRLICS
                     AKQQQTMLRVSIDGVEWSDIKFFQLAAQWPTHVKHFPVGLFSGSKPT"
     exon            451..538
                     /gene="Pacs1"
                     /gene_synonym="Pacs-1"
                     /inference="alignment:Splign:2.1.0"
     exon            539..628
                     /gene="Pacs1"
                     /gene_synonym="Pacs-1"
                     /inference="alignment:Splign:2.1.0"
     exon            629..754
                     /gene="Pacs1"
                     /gene_synonym="Pacs-1"
                     /inference="alignment:Splign:2.1.0"
     exon            755..899
                     /gene="Pacs1"
                     /gene_synonym="Pacs-1"
                     /inference="alignment:Splign:2.1.0"
     exon            900..991
                     /gene="Pacs1"
                     /gene_synonym="Pacs-1"
                     /inference="alignment:Splign:2.1.0"
     exon            992..1072
                     /gene="Pacs1"
                     /gene_synonym="Pacs-1"
                     /inference="alignment:Splign:2.1.0"
     exon            1073..1132
                     /gene="Pacs1"
                     /gene_synonym="Pacs-1"
                     /inference="alignment:Splign:2.1.0"
     exon            1133..1293
                     /gene="Pacs1"
                     /gene_synonym="Pacs-1"
                     /inference="alignment:Splign:2.1.0"
     exon            1294..1387
                     /gene="Pacs1"
                     /gene_synonym="Pacs-1"
                     /inference="alignment:Splign:2.1.0"
     exon            1388..1468
                     /gene="Pacs1"
                     /gene_synonym="Pacs-1"
                     /inference="alignment:Splign:2.1.0"
     exon            1469..1584
                     /gene="Pacs1"
                     /gene_synonym="Pacs-1"
                     /inference="alignment:Splign:2.1.0"
     exon            1585..1720
                     /gene="Pacs1"
                     /gene_synonym="Pacs-1"
                     /inference="alignment:Splign:2.1.0"
     exon            1721..1825
                     /gene="Pacs1"
                     /gene_synonym="Pacs-1"
                     /inference="alignment:Splign:2.1.0"
     exon            1826..1932
                     /gene="Pacs1"
                     /gene_synonym="Pacs-1"
                     /inference="alignment:Splign:2.1.0"
     exon            1933..2087
                     /gene="Pacs1"
                     /gene_synonym="Pacs-1"
                     /inference="alignment:Splign:2.1.0"
     exon            2088..2198
                     /gene="Pacs1"
                     /gene_synonym="Pacs-1"
                     /inference="alignment:Splign:2.1.0"
     exon            2199..2301
                     /gene="Pacs1"
                     /gene_synonym="Pacs-1"
                     /inference="alignment:Splign:2.1.0"
     exon            2302..2344
                     /gene="Pacs1"
                     /gene_synonym="Pacs-1"
                     /inference="alignment:Splign:2.1.0"
     exon            2345..2387
                     /gene="Pacs1"
                     /gene_synonym="Pacs-1"
                     /inference="alignment:Splign:2.1.0"
     exon            2388..2523
                     /gene="Pacs1"
                     /gene_synonym="Pacs-1"
                     /inference="alignment:Splign:2.1.0"
     exon            2524..2750
                     /gene="Pacs1"
                     /gene_synonym="Pacs-1"
                     /inference="alignment:Splign:2.1.0"
     exon            2751..2870
                     /gene="Pacs1"
                     /gene_synonym="Pacs-1"
                     /inference="alignment:Splign:2.1.0"
     exon            2871..4184
                     /gene="Pacs1"
                     /gene_synonym="Pacs-1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gacgcgctga gccgctgccg ccgcgggggg gaagcctgcg agtagctcgc gtgcccgcag
       61 tccgcgtaag ccccgcgccc cttccacccc tggccaggcc atggcggaac gtggaggggc
      121 gggcggtggt cccggaggcg ccgggggcgg cagcagtcag cggggctctg gggttgccca
      181 gtccccgcag cagcagccgc cgcagcagcc atctcagccg caacagccaa cgccccccaa
      241 actggcccag gccacctcgt cctcctcgtc cacctcggct gcggccgcct cctcctcgtc
      301 ctcctccacc tccacctcca tggccgtcgc ggtggcctcg ggctctgcgc ctcccggcgg
      361 tccgggacca ggccgcaccc ccgccccagt gcagatgaat ttgtatgcta cctgggaggt
      421 ggaccggagc tcatccagct gcgtgcccag actcttcagt ttgactctga agaaacttgt
      481 tatgcttaaa gaaatggaca aagatcttaa ctcagtagtc attgctgtga agctgcaggg
      541 ttcaaaaagg attcttcgct ctaatgagat catccttcca gccagtggcc tggtggaaac
      601 agagctccag ttaaccttct ccctccagta ccctcatttc cttaagcgag atgccaacaa
      661 actgcagatt atgttgcaaa ggaggaagcg gtacaagaac cggactatct tgggctataa
      721 aaccttggct gtgggactca tcaacatggc agaggtgatg caacacccta acgagggtgc
      781 tttagtactt ggcctgcata gcaacgtaaa ggatgtctct gtgcctgtgg cagaaataaa
      841 aatctactct ttatccagcc agcccattga ccatgaagga atcaagtcta agctgtctga
      901 tcgctcccca gatattgaca actactctga agaagaggag gaaagcttct cctcagagca
      961 ggaaggcagt gatgacccat tacatggaca ggacctattc tatgaagatg aagatcttcg
     1021 gaaagtaaag aagactcgaa ggaaactgac ctcaacctca gccatcacta ggcaaccgaa
     1081 catcaaacag aagtttgtgg ccctcctgaa acgattcaaa gtttctgatg aggtgggctt
     1141 tgggctagaa catgtgtcaa gggagcagat tcgggaagtg gaagaggacc tggatgaact
     1201 atacgacagt ctagaaatgt acaaccccag cgacagtggc cctgagatgg aagaaacaga
     1261 aagcatcctc agcaccccaa agcccaagct caagcccttc tttgagggga tgtctcagtc
     1321 cagctcacag acggagatcg gcagtctcaa cagcaagggc agccttggaa aagacaccac
     1381 cagccctatg gaattggcag ctttagaaaa agttaagtct acttggatta aaaaccaaga
     1441 tgacagcttg actgaaacag acactttaga aatcactgac caggacatgt ttggagatgc
     1501 gagcacaagt ctggttgtac cagaaaaagt caaaactcct atgaagtcca gcaaagctga
     1561 tctgcagggc tccgcctcgc cgagcaaggt ggaagggaca cacacacctc gccaaaagag
     1621 gagcactccc ctgaaggagc ggcagctctc caagcccctg agtgagagga ccaacagctc
     1681 tgacagtgag cgctctcctg acctagggca cagcacacag attccacgaa aggtggtata
     1741 cgatcaactg aatcagatcc tggtttccga tgcagcgctc cctgagaatg tcatcctggt
     1801 gaacaccacg gactggcagg gccagtatgt ggccgaattg cttcaagacc agaggaagcc
     1861 tgttgtgtgt acctgctcaa cagtggaggt ccaggccgtg ttgtctgccc tgctcactag
     1921 gattcagcgc tactgcaact gcaactcatc tatgccgagg ccagtcaagg tggcagctgt
     1981 gggcagccag agttacctga gctccatcct tcggtttttt gtcaagtccc ttgccagcaa
     2041 gaccccggac tggctgggcc acatgcgctt cctcatcgtt cccctaggtt ctcatccagt
     2101 ggccaaatac ttgggctcag tagatagtag atatagcagc acctttcttg attctgcttg
     2161 gagagacctg ttcagtcgct cagagcctcc agtgtcagag ccactggatg tggtgggtcg
     2221 tgtgatgcag tatgtcaatg gagctaccac aacgcaccag ctgcctgtgg ctgaagccat
     2281 gttgacctgc aggcataagt tccctgatga agactcctac cagaagttta tccccttcat
     2341 tggtgttgtg aaagtgggcc ttgttgaaga ctcgccctcc actgcaggtg atggggacga
     2401 ttcacctgtg gtcagcctta ctgtgccctc cacatcacca ccctcaagct cgggcctgag
     2461 ccgagatgcc acagctaccc ctccctcatc cccatccatg agcagtgccc tcgccatcgt
     2521 ggggagccca aatagccctt atggggatgt gattggcctc caggtggatt actggctggg
     2581 ccaccctggg gagcgaagga gagaaggtga taagagggac gccagttcaa agaataccct
     2641 caagagtgtc ttccgctcag tgcaggtttc tcgcctgccc catgcagggg aagcccagct
     2701 ttctggcacc atggcaatga ctgtggtcac caaagagaag aacaagaaag tgcccactat
     2761 cttcctgagc aagaagcccc gggaaaagga ggtggattct aagagccaag tcatcgaggg
     2821 catcagccgc ctcatctgtt ctgcaaagca gcagcaaacc atgctgagag tgtccattga
     2881 tggagttgaa tggagtgaca tcaagttctt ccagctggca gctcagtggc ccactcatgt
     2941 caagcacttc ccagtgggac tcttcagtgg cagcaaaccc acctgagacc tgcctcccaa
     3001 ccactccctc ctggcactgc cacccagccc agcctccttt cctagcactg gggcttgcct
     3061 ccacttgccc agtcctgaag gacactgcca ctggggatgc agtcctccct gctcactgcc
     3121 cagccatctc tgcccagctc ccccctgttc caggcccaga gctgggtgat cctgccttct
     3181 ggtgcccata attcctgtaa ttgaataatc tgggccttcc ttcacctcac ccctgcagcg
     3241 ctggtaccct ttctagaaat gaaacacctg gagttctggt acacagggag acagcccagc
     3301 atcctacata agctggccac ccagctctgc atttctaagg ctctgttgcc tgttgtactc
     3361 accctgcctt cctccagcag ggctggggcc tcctgccatt cctcacctgc ctcacagttt
     3421 cccagtaggg ggaaggagga tggcacctgg gcatcctgga gtttctggga ttgaagggac
     3481 cttcccagtc tcccatgcat gatttcctga cacttcaagt cgcttggatg tcctgtgttt
     3541 tgtgtgtttt tagttgtttg ggtaacttgt cctgtgcaca ggtccttaag gctccttctc
     3601 cctctgcctc ccagcctcct acctaacatt gctctgtggc ttcatgaggt aggagacagc
     3661 aaacccaccc acccacccac cccttcaccc ctcaacacat acatcatctg tggctctcat
     3721 ccagtcatat tgtccccctc tcctgtgtca gcttgcctcc tggctctgct ctgtcatccc
     3781 acttccttca tggcagggca gcagaatgag gcccttctcc accaggtctc cctccagcag
     3841 cctccttccc tctctcagcc atgaatgggt cccagaccta cctcagcctc cttatcagtg
     3901 tcttcatgag aggctgagga caagggacag atctggccca gcctccatgc cctctgtgtc
     3961 ctatggcacc tcagagcttc tccgttgccc ctcagtgttt cctagcagtg tggcacggaa
     4021 ctgcacttgg aacctagttt tggtgttctt cacatccaaa actcttaagc ccctcccgct
     4081 gcccagcctg tccagagtat ctcctgggcc tgagaataag tggggtggga agactggggc
     4141 catgttgggt tttttcattc aataaactgg tgatttctta ccaaaaaaaa aaaaaaaa
//
