LOCUS       NM_001100538            2611 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus poly(A) binding protein, cytoplasmic 4 (Pabpc4),
            mRNA.
ACCESSION   NM_001100538 XM_001054606 XM_216517
VERSION     NM_001100538.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2611)
  AUTHORS   Kini,H.K., Kong,J. and Liebhaber,S.A.
  TITLE     Cytoplasmic poly(A) binding protein C4 serves a critical role in
            erythroid differentiation
  JOURNAL   Mol Cell Biol 34 (7), 1300-1309 (2014)
   PUBMED   24469397
REFERENCE   2  (bases 1 to 2611)
  AUTHORS   Baltz,A.G., Munschauer,M., Schwanhausser,B., Vasile,A.,
            Murakawa,Y., Schueler,M., Youngs,N., Penfold-Brown,D., Drew,K.,
            Milek,M., Wyler,E., Bonneau,R., Selbach,M., Dieterich,C. and
            Landthaler,M.
  TITLE     The mRNA-bound proteome and its global occupancy profile on
            protein-coding transcripts
  JOURNAL   Mol Cell 46 (5), 674-690 (2012)
   PUBMED   22681889
REFERENCE   3  (bases 1 to 2611)
  AUTHORS   Castello,A., Fischer,B., Eichelbaum,K., Horos,R., Beckmann,B.M.,
            Strein,C., Davey,N.E., Humphreys,D.T., Preiss,T., Steinmetz,L.M.,
            Krijgsveld,J. and Hentze,M.W.
  TITLE     Insights into RNA biology from an atlas of mammalian mRNA-binding
            proteins
  JOURNAL   Cell 149 (6), 1393-1406 (2012)
   PUBMED   22658674
REFERENCE   4  (bases 1 to 2611)
  AUTHORS   Burgess,H.M., Richardson,W.A., Anderson,R.C., Salaun,C.,
            Graham,S.V. and Gray,N.K.
  TITLE     Nuclear relocalisation of cytoplasmic poly(A)-binding proteins
            PABP1 and PABP4 in response to UV irradiation reveals
            mRNA-dependent export of metazoan PABPs
  JOURNAL   J Cell Sci 124 (Pt 19), 3344-3355 (2011)
   PUBMED   21940797
REFERENCE   5  (bases 1 to 2611)
  AUTHORS   Jonson,L., Vikesaa,J., Krogh,A., Nielsen,L.K., Hansen,Tv.,
            Borup,R., Johnsen,A.H., Christiansen,J. and Nielsen,F.C.
  TITLE     Molecular composition of IMP1 ribonucleoprotein granules
  JOURNAL   Mol Cell Proteomics 6 (5), 798-811 (2007)
   PUBMED   17289661
REFERENCE   6  (bases 1 to 2611)
  AUTHORS   Yang,H., Duckett,C.S. and Lindsten,T.
  TITLE     iPABP, an inducible poly(A)-binding protein detected in activated
            human T cells
  JOURNAL   Mol Cell Biol 15 (12), 6770-6776 (1995)
   PUBMED   8524242
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC166452.1.
            
            [WARNING] On Mar 19, 2025 this sequence was replaced by
            NM_001100538.2.
            
            On or before Sep 10, 2008 this sequence version replaced
            XM_001054606.1, XM_216517.4.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC166452.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-2611              BC166452.1         6-2616
FEATURES             Location/Qualifiers
     source          1..2611
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="5"
                     /map="5q36"
     gene            1..2611
                     /gene="Pabpc4"
                     /note="poly(A) binding protein, cytoplasmic 4"
                     /db_xref="GeneID:298510"
                     /db_xref="RGD:1305015"
     exon            1..561
                     /gene="Pabpc4"
                     /inference="alignment:Splign:2.1.0"
     CDS             369..2303
                     /gene="Pabpc4"
                     /note="poly(A) binding protein, cytoplasmic 4 (inducible
                     form)"
                     /codon_start=1
                     /product="polyadenylate-binding protein 4"
                     /protein_id="NP_001094008.1"
                     /db_xref="GeneID:298510"
                     /db_xref="RGD:1305015"
                     /translation="MNAAASSYPMASLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCR
                     DMITRRSLGYAYVNFQQPADAERALDTMNFDVIKGKPIRIMWSQRDPSLRKSGVGNVF
                     IKNLDKSIDNKALYDTFSAFGNILSCKVVCDENGSKGYAFVHFETQEAANKAIEKMNG
                     MLLNDRKVFVGRFKSRKEREAELGAKAKEFTNVYIKNFGEEVDDENLRELFSQFGKTL
                     SVKVMRDCSGKSKGFGFVSYEKHEDANKAVEEMNGKEMSGKSIFVGRAQKKVERQAEL
                     KRKFEQLKQERISRYQGVNLYIKNLDDTIDDEKLRKEFSPFGSITSAKVMLEDGRSKG
                     FGFVCFSSPEEATKAVTEMNGRIVGSKPLYVALAQRKEERKAHLTNQYMQRVAGMRAL
                     PANAILNQFQPAAGGYFVPAVPQAQGRPPYYTPNQLAQMRPNPRWQQGGRPQGFQGMP
                     SALRQSGPRPALRHLAPTGSECPDRLAMDFGGAGAAQQGLTDSCQSGGVPTAVPNLAP
                     RATVAAAAPRAVAPYKYASNVRSPHPAIQPLQAPQPAVHVQGQEPLTASMLAAAPPQE
                     QKQMLGERLFPLIQTMHSNLAGKITGMLLEIDNSELLHMLESPESLRSKVDEAVAVLQ
                     AHHAKKEAAQKVGTVAAATS"
     exon            562..755
                     /gene="Pabpc4"
                     /inference="alignment:Splign:2.1.0"
     exon            756..871
                     /gene="Pabpc4"
                     /inference="alignment:Splign:2.1.0"
     exon            872..1011
                     /gene="Pabpc4"
                     /inference="alignment:Splign:2.1.0"
     exon            1012..1106
                     /gene="Pabpc4"
                     /inference="alignment:Splign:2.1.0"
     exon            1107..1244
                     /gene="Pabpc4"
                     /inference="alignment:Splign:2.1.0"
     exon            1245..1340
                     /gene="Pabpc4"
                     /inference="alignment:Splign:2.1.0"
     exon            1341..1613
                     /gene="Pabpc4"
                     /inference="alignment:Splign:2.1.0"
     exon            1614..1701
                     /gene="Pabpc4"
                     /inference="alignment:Splign:2.1.0"
     exon            1702..1773
                     /gene="Pabpc4"
                     /inference="alignment:Splign:2.1.0"
     exon            1774..1860
                     /gene="Pabpc4"
                     /inference="alignment:Splign:2.1.0"
     exon            1861..1988
                     /gene="Pabpc4"
                     /inference="alignment:Splign:2.1.0"
     exon            1989..2082
                     /gene="Pabpc4"
                     /inference="alignment:Splign:2.1.0"
     exon            2083..2213
                     /gene="Pabpc4"
                     /inference="alignment:Splign:2.1.0"
     exon            2214..2310
                     /gene="Pabpc4"
                     /inference="alignment:Splign:2.1.0"
     exon            2311..2611
                     /gene="Pabpc4"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gtgtccccaa ggccgctgtg agcgcagcat ctggctgcct ctagaaaaaa tttttgcccc
       61 ctctgcaagg ggattcccta cttcaatttt tatcttttaa gctccaagcc aggacagctg
      121 gagagtacaa actccaggag agggccatat tgtttttgag agccttttgt cttggggctt
      181 ttgcggtccg gtgtaagtcg tcccgcactc cggtcccgcc tcggagcctc cctgctccag
      241 cctctcccag cgtcgctggt gccacctgtg cgctgcggcg cgtgccacag ctcttcggag
      301 ccccttttgt cctgcagtag gccctgcaag aagtcctggc ggggctcggg gtagtagggg
      361 gtggggagat gaacgctgcg gccagcagct accccatggc ctccttatac gtgggcgatc
      421 tgcactccga tgtcaccgaa gccatgctgt atgaaaagtt cagccctgcg gggcctgtgc
      481 tgtccatccg ggtctgccgc gatatgatca cccgccgctc tctgggttat gcctacgtca
      541 acttccagca gccagctgac gctgagaggg ccttggacac catgaacttt gatgtgatta
      601 aggggaagcc aatccggatc atgtggtctc agagggaccc ctctttgagg aagtctggtg
      661 tgggaaatgt cttcatcaag aacctggaca agtctataga caacaaggca ctgtatgaca
      721 ctttctctgc cttcggaaac atcctgtcct gtaaggtggt ctgtgatgag aacggctcta
      781 agggttatgc ctttgtccac ttcgagaccc aagaggctgc caacaaggcc atcgagaaga
      841 tgaatggcat gctcctcaat gaccgcaaag tgttcgtggg cagattcaag tctcgcaaag
      901 agcgggaagc cgagcttgga gccaaggcca aggaattcac caatgtttat atcaaaaact
      961 ttggagaaga ggtggatgat gagaatctga gggagctatt cagccagttt ggtaagacct
     1021 taagtgtcaa ggtgatgaga gactgcagtg ggaagtccaa aggcttcggc ttcgtgagct
     1081 atgagaaaca tgaggatgcc aataaggctg tggaagaaat gaatggaaaa gaaatgagtg
     1141 ggaaatccat atttgtaggc cgtgctcaga aaaaagtaga acgtcaggcg gagttaaaac
     1201 ggaaattcga acagctgaag caggagagga ttagtcggta ccagggagtg aatctctaca
     1261 ttaagaactt ggatgacacc attgacgatg agaagttaag gaaagagttc tcaccctttg
     1321 gatcaatcac cagtgcgaag gtgatgctgg aagacgggag aagcaaaggg tttggctttg
     1381 tctgtttctc ctctcctgaa gaggcaacca aagcggtcac ggagatgaac ggacgcattg
     1441 tgggctccaa gcctctgtac gtcgccctgg cccagaggaa ggaggagcgg aaggctcacc
     1501 tgactaacca gtatatgcag cgtgtggcag gaatgagagc gctccctgcc aacgccatct
     1561 taaatcagtt ccagcctgca gctggtggct actttgtgcc ggcagtgcca caggcccagg
     1621 gaagacctcc atattacaca cctaatcaat tagcgcaaat gaggcctaat ccacgctggc
     1681 agcaaggcgg gagacctcaa ggcttccaag gaatgccaag tgccctgcgg caatctgggc
     1741 ctcgtccagc tcttcggcat ctggctccaa ctgggtctga gtgcccggac cgcttggcta
     1801 tggactttgg tggggctggt gccgcccagc aagggctgac tgacagctgc cagtctggag
     1861 gcgtccctac ggctgtgcca aaccttgcac ctcgtgctac agtcgctgct gctgctccca
     1921 gggctgtggc tccatacaag tatgcctcca atgtccgcag ccctcaccct gccattcagc
     1981 cgctgcaggc cccccagcct gcagtccatg tccagggtca agaacccctg actgcctcca
     2041 tgctggctgc agctcctccc caggagcaga agcagatgct gggggagcgt ttgttcccac
     2101 ttatccaaac aatgcattca aacctggctg gaaaaattac agggatgctg ctagaaatcg
     2161 acaactctga gctgctccac atgctggagt cccccgagtc cctccgttcc aaggtggatg
     2221 aagctgtggc agtcctgcag gctcatcatg ccaagaaaga agctgcccag aaggtgggca
     2281 ctgttgctgc tgctacctct taaaccagaa gagtcaaaag ccaaataacc cctcacggca
     2341 ttcagctgag gtctgaagac ttcctagttt gtctgtggac ctctttcaag aaccaagtta
     2401 caaattcaac aggtcatttt gtatcaaaag gtcaattatg aagcacctag aatttttcaa
     2461 ttataagaat atattctctg ggttctgttg tggcccagat gatggtaact tttttttcta
     2521 ttatgagttc tgtttttttt cccctctccc agaaattggt tttgatgtac ccaagactta
     2581 agtttctcaa taaaggaaat aaaatctcca a
//
