LOCUS       NM_134353               2190 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus poly(A) binding protein, cytoplasmic 1 (Pabpc1),
            mRNA.
ACCESSION   NM_134353
VERSION     NM_134353.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2190)
  AUTHORS   Tan,J., Xie,Y., Yao,A., Qin,Y., Li,L., Shen,L., Zhang,X., Xu,C.,
            Jiang,X., Wang,A. and Yan,Z.
  TITLE     Long noncoding RNA-dependent regulation of vascular smooth muscle
            cell proliferation and migration in hypertension
  JOURNAL   Int J Biochem Cell Biol 118, 105653 (2020)
   PUBMED   31743794
  REMARK    GeneRIF: Long noncoding RNA-dependent regulation of vascular smooth
            muscle cell proliferation and migration in hypertension.
REFERENCE   2  (bases 1 to 2190)
  AUTHORS   Copsey,A.C., Cooper,S., Parker,R., Lineham,E., Lapworth,C.,
            Jallad,D., Sweet,S. and Morley,S.J.
  TITLE     The helicase, DDX3X, interacts with poly(A)-binding protein 1
            (PABP1) and caprin-1 at the leading edge of migrating fibroblasts
            and is required for efficient cell spreading
  JOURNAL   Biochem J 474 (18), 3109-3120 (2017)
   PUBMED   28733330
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 2190)
  AUTHORS   Bayes,A., Collins,M.O., Reig-Viader,R., Gou,G., Goulding,D.,
            Izquierdo,A., Choudhary,J.S., Emes,R.D. and Grant,S.G.
  TITLE     Evolution of complexity in the zebrafish synapse proteome
  JOURNAL   Nat Commun 8, 14613 (2017)
   PUBMED   28252024
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 2190)
  AUTHORS   Suzuki,Y., Chin,W.X., Han,Q., Ichiyama,K., Lee,C.H., Eyo,Z.W.,
            Ebina,H., Takahashi,H., Takahashi,C., Tan,B.H., Hishiki,T.,
            Ohba,K., Matsuyama,T., Koyanagi,Y., Tan,Y.J., Sawasaki,T.,
            Chu,J.J., Vasudevan,S.G., Sano,K. and Yamamoto,N.
  TITLE     Characterization of RyDEN (C19orf66) as an Interferon-Stimulated
            Cellular Inhibitor against Dengue Virus Replication
  JOURNAL   PLoS Pathog 12 (1), e1005357 (2016)
   PUBMED   26735137
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 2190)
  AUTHORS   Berg,J.M., Lee,C., Chen,L., Galvan,L., Cepeda,C., Chen,J.Y.,
            Penagarikano,O., Stein,J.L., Li,A., Oguro-Ando,A., Miller,J.A.,
            Vashisht,A.A., Starks,M.E., Kite,E.P., Tam,E., Gdalyahu,A.,
            Al-Sharif,N.B., Burkett,Z.D., White,S.A., Fears,S.C., Levine,M.S.,
            Wohlschlegel,J.A. and Geschwind,D.H.
  TITLE     JAKMIP1, a Novel Regulator of Neuronal Translation, Modulates
            Synaptic Function and Autistic-like Behaviors in Mouse
  JOURNAL   Neuron 88 (6), 1173-1191 (2015)
   PUBMED   26627310
REFERENCE   6  (bases 1 to 2190)
  AUTHORS   Linker,K., Pautz,A., Fechir,M., Hubrich,T., Greeve,J. and
            Kleinert,H.
  TITLE     Involvement of KSRP in the post-transcriptional regulation of human
            iNOS expression-complex interplay of KSRP with TTP and HuR
  JOURNAL   Nucleic Acids Res 33 (15), 4813-4827 (2005)
   PUBMED   16126846
  REMARK    Publication Status: Online-Only
REFERENCE   7  (bases 1 to 2190)
  AUTHORS   Ralser,M., Albrecht,M., Nonhoff,U., Lengauer,T., Lehrach,H. and
            Krobitsch,S.
  TITLE     An integrative approach to gain insights into the cellular function
            of human ataxin-2
  JOURNAL   J Mol Biol 346 (1), 203-214 (2005)
   PUBMED   15663938
REFERENCE   8  (bases 1 to 2190)
  AUTHORS   Villace,P., Marion,R.M. and Ortin,J.
  TITLE     The composition of Staufen-containing RNA granules from human cells
            indicates their role in the regulated transport and translation of
            messenger RNAs
  JOURNAL   Nucleic Acids Res 32 (8), 2411-2420 (2004)
   PUBMED   15121898
  REMARK    Publication Status: Online-Only
REFERENCE   9  (bases 1 to 2190)
  AUTHORS   Jurica,M.S., Licklider,L.J., Gygi,S.R., Grigorieff,N. and
            Moore,M.J.
  TITLE     Purification and characterization of native spliceosomes suitable
            for three-dimensional structural analysis
  JOURNAL   RNA 8 (4), 426-439 (2002)
   PUBMED   11991638
REFERENCE   10 (bases 1 to 2190)
  AUTHORS   Mohr,E., Prakash,N., Vieluf,K., Fuhrmann,C., Buck,F. and Richter,D.
  TITLE     Vasopressin mRNA localization in nerve cells: characterization of
            cis-acting elements and trans-acting factors
  JOURNAL   Proc Natl Acad Sci U S A 98 (13), 7072-7079 (2001)
   PUBMED   11416190
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AJ298278.1.
            
            On Jun 10, 2007 this sequence version replaced NM_134353.2.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AJ298278.1, BC083176.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5756307, SAMEA5760383
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2190
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="7"
                     /map="7q22"
     gene            1..2190
                     /gene="Pabpc1"
                     /gene_synonym="Pabp; PABP 1; Pabp1"
                     /note="poly(A) binding protein, cytoplasmic 1"
                     /db_xref="GeneID:171350"
                     /db_xref="RGD:619838"
     exon            1..392
                     /gene="Pabpc1"
                     /gene_synonym="Pabp; PABP 1; Pabp1"
                     /inference="alignment:Splign:2.1.0"
     CDS             200..2110
                     /gene="Pabpc1"
                     /gene_synonym="Pabp; PABP 1; Pabp1"
                     /note="poly(A)-binding protein 1; PABP-1"
                     /codon_start=1
                     /product="polyadenylate-binding protein 1"
                     /protein_id="NP_599180.1"
                     /db_xref="GeneID:171350"
                     /db_xref="RGD:619838"
                     /translation="MNPSAPSYPMASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCR
                     DMITRRSLGYAYVNFQQPADAERALDTMNFDVIKGKPVRIMWSQRDPSLRKSGVGNIF
                     IKNLDKSIDNKALYDTFSAFGNILSCKVVCDENGSKGYGFVHFETQEAAERAIEKMNG
                     MLLNDRKVFVGRFKSRKEREAELGARAKEFTNVYIKNFGEDMDDERLKELFGKFGPAL
                     SVKVMTDESGKSKGFGFVSFERHEDAQKAVDEMNGKELNGKQIYVGRAQKKVERQTEL
                     KRKFEQMKQDRITRYQGVNLYVKNLDDGIDDERLRKEFSPFGTITSAKVMMEGGRSKG
                     FGFVCFSSPEEATKAVTEMNGRIVATKPLYVALAQRKEERQAHLTNQYMQRMASVRAV
                     PNPVINPYQPAPPSGYFMAAIPQTQNRAAYYPPSQIAQLRPSPRWTAQGARPHPFQNM
                     PGAIRPAAPRPPFSTMRPASSQVPRVMSTQRVANTSTQTMGPRPAAAATAATPAVRTV
                     PQYKYAAGVRNPQQHLNAQPQVTMQQPAVHVQGQEPLTASMLASAPPQEQKQMLGERL
                     FPLIQAMHPSLAGKITGMLLEIDNSELLHMLESPESLRSKVDEAVAVLQAHQAKEAAQ
                     KAVNSATGVPTV"
     exon            393..586
                     /gene="Pabpc1"
                     /gene_synonym="Pabp; PABP 1; Pabp1"
                     /inference="alignment:Splign:2.1.0"
     exon            587..702
                     /gene="Pabpc1"
                     /gene_synonym="Pabp; PABP 1; Pabp1"
                     /inference="alignment:Splign:2.1.0"
     exon            703..842
                     /gene="Pabpc1"
                     /gene_synonym="Pabp; PABP 1; Pabp1"
                     /inference="alignment:Splign:2.1.0"
     exon            843..937
                     /gene="Pabpc1"
                     /gene_synonym="Pabp; PABP 1; Pabp1"
                     /inference="alignment:Splign:2.1.0"
     exon            938..1075
                     /gene="Pabpc1"
                     /gene_synonym="Pabp; PABP 1; Pabp1"
                     /inference="alignment:Splign:2.1.0"
     exon            1076..1171
                     /gene="Pabpc1"
                     /gene_synonym="Pabp; PABP 1; Pabp1"
                     /inference="alignment:Splign:2.1.0"
     exon            1172..1444
                     /gene="Pabpc1"
                     /gene_synonym="Pabp; PABP 1; Pabp1"
                     /inference="alignment:Splign:2.1.0"
     exon            1445..1535
                     /gene="Pabpc1"
                     /gene_synonym="Pabp; PABP 1; Pabp1"
                     /inference="alignment:Splign:2.1.0"
     exon            1536..1646
                     /gene="Pabpc1"
                     /gene_synonym="Pabp; PABP 1; Pabp1"
                     /inference="alignment:Splign:2.1.0"
     exon            1647..1801
                     /gene="Pabpc1"
                     /gene_synonym="Pabp; PABP 1; Pabp1"
                     /inference="alignment:Splign:2.1.0"
     exon            1802..1886
                     /gene="Pabpc1"
                     /gene_synonym="Pabp; PABP 1; Pabp1"
                     /inference="alignment:Splign:2.1.0"
     exon            1887..2017
                     /gene="Pabpc1"
                     /gene_synonym="Pabp; PABP 1; Pabp1"
                     /inference="alignment:Splign:2.1.0"
     exon            2018..2110
                     /gene="Pabpc1"
                     /gene_synonym="Pabp; PABP 1; Pabp1"
                     /inference="alignment:Splign:2.1.0"
     exon            2111..2190
                     /gene="Pabpc1"
                     /gene_synonym="Pabp; PABP 1; Pabp1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ctgccgcccg gacccagcac cgccagcctc gctcccccgg ttccacggcc gttgagtacg
       61 cgtcgattcc ggttgaattt tgtccctctg cgctcgcccc cgctcccctc cccccggctc
      121 cgtcccccgg ccccgcactc gctctcctcc tctcacggga aaggtcgcgg cctgcggccc
      181 cgcgggcagc cgtgccgaga tgaaccccag cgcccccagc taccccatgg cctctctgta
      241 cgtgggggac ctgcaccccg acgtgaccga ggcgatgctc tacgagaagt tcagcccggc
      301 cgggcccatc ctctccatcc gggtctgcag ggacatgatc acccgccgct ccttgggcta
      361 cgcgtacgtg aacttccagc agccggcgga cgcggaacgt gctttggaca ccatgaattt
      421 tgatgttata aagggcaagc cagtacgcat catgtggtct cagcgtgatc catcacttcg
      481 taaaagtgga gtaggcaaca tattcattaa aaatttggac aaatccattg acaataaagc
      541 actgtatgat acgttttctg cgtttggtaa catcctttca tgtaaggtgg tttgtgatga
      601 aaatggctcc aagggctatg gatttgtaca ttttgaaaca caggaagcag ctgaaagagc
      661 tattgaaaaa atgaatggaa tgcttctaaa tgatcgtaaa gtgtttgttg gtcgatttaa
      721 atctcggaag gaacgagaag cagaacttgg agcaagggca aaggagttca ccaatgttta
      781 catcaagaac tttggagaag acatggatga tgagcgtctt aaggaactct ttggcaagtt
      841 tgggcctgcc ttaagtgtga aagtaatgac agatgaaagt ggaaaatcca aaggatttgg
      901 atttgtaagc tttgaaaggc atgaagatgc gcagaaagct gtggatgaga tgaatgggaa
      961 ggagctcaat ggaaaacaga tttatgttgg tcgagctcag aaaaaagtgg aacggcagac
     1021 ggaacttaag cgcaaatttg agcagatgaa gcaagacagg atcaccagat atcagggtgt
     1081 taacctttat gtgaaaaatc ttgatgacgg aattgatgat gagcgtctcc ggaaagagtt
     1141 ttctccattt ggtacaatca ctagtgcaaa agtaatgatg gagggtgggc gcagcaaagg
     1201 atttggtttt gtatgtttct cctcccctga agaagccact aaagcagtta cggagatgaa
     1261 tggtagaatt gtggccacca agccactcta tgtagcttta gctcagcgca aagaagagcg
     1321 ccaggctcac ctcactaacc agtatatgca gaggatggca agtgtacgag ctgtgcccaa
     1381 tcctgtgatc aacccctacc agccagcacc tccttcaggt tacttcatgg cagctatccc
     1441 acagactcag aaccgtgctg catactatcc tcctagccaa attgctcaac taagaccaag
     1501 tcctcgctgg actgctcagg gtgccagacc tcatccattc cagaatatgc ccggtgctat
     1561 ccgcccagct gctcctagac caccatttag tacgatgaga ccagcttcct cacaggttcc
     1621 acgagtcatg tcaacacagc gtgttgctaa cacatcaaca cagacaatgg gtccacgtcc
     1681 tgcagctgct gctactgcag ccactcctgc tgtccgcact gttccccagt ataaatacgc
     1741 tgcgggagtc cgcaatcccc agcaacatct taatgcacag ccacaagtta ccatgcaaca
     1801 gcctgcggtt catgtgcaag gtcaagaacc tttaactgct tccatgttgg catctgcacc
     1861 cccgcaagag caaaagcaaa tgttgggtga acggctgttt cctcttattc aagccatgca
     1921 cccttctctt gctggcaaaa ttactggcat gctgttggag attgataact cagaattgct
     1981 tcacatgctt gagtctccag agtctctccg ctcaaaggtc gatgaagctg tagctgtact
     2041 acaagcccac caagcgaaag aggctgccca gaaagcagtg aacagtgcca ctggtgttcc
     2101 aactgtctaa attgatcagg gaccacgaac agaaactcgt gcttcaccga agaaaaatat
     2161 cttaaacatc gaaaaattta aatattatga
//
