LOCUS       NM_198775               1660 bp    mRNA    linear   ROD 12-DEC-2024
DEFINITION  Rattus norvegicus prolyl 4-hydroxylase subunit alpha 3 (P4ha3),
            mRNA.
ACCESSION   NM_198775 XM_341890
VERSION     NM_198775.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1660)
  AUTHORS   Kukkola,L., Hieta,R., Kivirikko,K.I. and Myllyharju,J.
  TITLE     Identification and characterization of a third human, rat, and
            mouse collagen prolyl 4-hydroxylase isoenzyme
  JOURNAL   J Biol Chem 278 (48), 47685-47693 (2003)
   PUBMED   14500733
  REMARK    GeneRIF: analysis of collagen prolyl 4-hydroxylase isoenzyme 3, its
            expression and catalytic properties
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AY313450.1.
            
            On Dec 17, 2003 this sequence version replaced XM_341890.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AY313450.1, SRR8487227.71417.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760396, SAMEA5760433
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1660
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="Sprague-Dawley"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q32"
     gene            1..1660
                     /gene="P4ha3"
                     /note="prolyl 4-hydroxylase subunit alpha 3"
                     /db_xref="GeneID:361612"
                     /db_xref="RGD:735150"
     exon            1..225
                     /gene="P4ha3"
                     /inference="alignment:Splign:2.1.0"
     CDS             26..1660
                     /gene="P4ha3"
                     /EC_number="1.14.11.2"
                     /note="4-PH alpha-3;
                     procollagen-proline,2-oxoglutarate-4-dioxygenase subunit
                     alpha-3; procollagen-proline, 2-oxoglutarate 4-dioxygenase
                     (proline 4-hydroxylase), alpha polypeptide III; collagen
                     prolyl 4-hydroxylase alpha III subunit; prolyl
                     4-hydroxylase, alpha polypeptide III"
                     /codon_start=1
                     /product="prolyl 4-hydroxylase subunit alpha-3 precursor"
                     /protein_id="NP_942070.1"
                     /db_xref="GeneID:361612"
                     /db_xref="RGD:735150"
                     /translation="MGPGARLAALLVLLKLGVGDPAAAAGREDTFSALTSVARALAPE
                     RRLLGTLRRYLRGEEARLRDLTRFYDKVLSLHEDLKIPVVNPLLVFTLIKRLPSDWRN
                     VVHSLEATENIRAPKDGYEKVEQDLPAFEDLEGAARALMRLQDAYMLNVKGLAQGVFQ
                     RVTGSSITDLYSPRQLFSLTADDCFQVGKVAYDTGDYYHAIPWLEEAVSLFRRSYGEW
                     KTEDEASLEDALDYLAFACYQVGNVSCALSLSREFLVYSPDNKRMARNVLKYERLLAE
                     NGHLMAAETAIQRPNVPHLQTRDTYEGLCQTLGSQPTHYQIPSLYCSYETNSSPYLLL
                     QPARKEVIHLRPLVALYHDFVSDEEAQKIRELAEPWLQRSVVASGEKQLQVEYRISKS
                     AWLKDTVDPVLVTLDRRIAALTGLDIQPPYAEYLQVVNYGIGGHYEPHFDHATSPSSP
                     LYKMKSGNRAATLMIYLSSVEAGGATAFIYGNFSVPVVKNAALFWWNLHRSGEGDDDT
                     LHAGCPVLVGDKWVANKWIHEYGQEFRRPCDTNPED"
     exon            226..368
                     /gene="P4ha3"
                     /inference="alignment:Splign:2.1.0"
     exon            369..592
                     /gene="P4ha3"
                     /inference="alignment:Splign:2.1.0"
     exon            593..742
                     /gene="P4ha3"
                     /inference="alignment:Splign:2.1.0"
     exon            743..794
                     /gene="P4ha3"
                     /inference="alignment:Splign:2.1.0"
     exon            795..958
                     /gene="P4ha3"
                     /inference="alignment:Splign:2.1.0"
     exon            959..1135
                     /gene="P4ha3"
                     /inference="alignment:Splign:2.1.0"
     exon            1136..1200
                     /gene="P4ha3"
                     /inference="alignment:Splign:2.1.0"
     exon            1201..1360
                     /gene="P4ha3"
                     /inference="alignment:Splign:2.1.0"
     exon            1361..1423
                     /gene="P4ha3"
                     /inference="alignment:Splign:2.1.0"
     exon            1424..1492
                     /gene="P4ha3"
                     /inference="alignment:Splign:2.1.0"
     exon            1493..1589
                     /gene="P4ha3"
                     /inference="alignment:Splign:2.1.0"
     exon            1590..1660
                     /gene="P4ha3"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gcgcggaggg acgcgcgacc ccgcgatggg cccaggggcg cggctggcgg cgctgctggt
       61 gctgctgaag ctcggggtcg gagaccctgc ggcggccgcg gggcgggagg acacgttctc
      121 cgctctgacc agcgtggcgc gcgccctggc gcccgagcgc cggctgctgg ggacactgag
      181 gcgctacctg cgcggcgagg aggcgcggct gcgcgacctg accagattct atgacaaggt
      241 actttctttg cacgaggact tgaagatccc tgtagtgaat cccctacttg tcttcactct
      301 catcaaacgt ctgccgtctg actggaggaa tgtggtacac agtctggaag ccactgagaa
      361 tatccgagct ccgaaggatg gttatgagaa ggtggagcaa gaccttcctg cctttgagga
      421 cctcgaggga gcagcaaggg ccctgatgcg actgcaggac gcgtacatgc tcaatgtgaa
      481 gggcttggcc cagggcgtct tccagagagt cacgggctcc tccatcactg acctgtacag
      541 tcccaggcag ctcttctctc tcacagcgga tgactgcttc caagttggta aggtggccta
      601 tgacacgggg gattactacc atgccattcc gtggctggag gaagctgtca gtctcttccg
      661 aagatcttac ggagagtgga agacagagga tgaggccagt ctggaagacg ccctggatta
      721 tttggccttt gcctgttacc aggtaggaaa tgtttcgtgt gccctcagcc tctctcgaga
      781 gttccttgtc tacagcccag acaataagag gatggccagg aatgtgttga aatacgaaag
      841 gctcttggct gagaatggtc acctgatggc ggctgagaca gcaattcaga ggcccaacgt
      901 accccacctc cagaccaggg acacctatga ggggctatgc cagaccctgg gctcccagcc
      961 aacacactac caaatcccca gcctctactg ctcctacgag accaattcca gcccctacct
     1021 actgctccag cccgcacgca aggaggtcat ccacctgcgg cccctcgtgg ctctctacca
     1081 tgatttcgtc agtgatgagg aagcccagaa aatccgagag ctcgcagaac cgtggctcca
     1141 gagatcagtg gtggcttcag gggaaaagca gttacaagtg gagtaccgca tcagcaaaag
     1201 tgcctggcta aaggacacgg ttgacccagt gctggtgacc cttgaccgcc gcattgctgc
     1261 cctcacaggc ctcgacatcc agcctccgta cgcagagtat ctccaggtgg tgaactatgg
     1321 aattggaggg cactatgagc ctcacttcga ccatgctacg tcgcccagca gccccctgta
     1381 caagatgaag tccgggaacc gagcggcaac gcttatgata tatctgagct ccgtagaagc
     1441 tggaggagcc acagccttta tctatggcaa cttcagtgtg cctgtggtta agaatgctgc
     1501 actgttttgg tggaacttgc acaggagtgg agagggggat gatgacacac ttcacgctgg
     1561 ctgccctgtg ctggtgggag acaagtgggt ggccaacaag tggatacacg agtatggaca
     1621 ggaattccga agaccctgcg acaccaatcc tgaagactga
//
