LOCUS       NM_001107572            2993 bp    mRNA    linear   ROD 22-MAR-2023
DEFINITION  Rattus norvegicus ovo like transcriptional repressor 1 (Ovol1),
            mRNA.
ACCESSION   NM_001107572 XM_001070450 XM_219513
VERSION     NM_001107572.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2993)
  AUTHORS   Lee B, Villarreal-Ponce A, Fallahi M, Ovadia J, Sun P, Yu QC, Ito
            S, Sinha S, Nie Q and Dai X.
  TITLE     Transcriptional mechanisms link epithelial plasticity to adhesion
            and differentiation of epidermal progenitor cells
  JOURNAL   Dev Cell 29 (1), 47-58 (2014)
   PUBMED   24735878
REFERENCE   2  (bases 1 to 2993)
  AUTHORS   Vetere A, Li WC, Paroni F, Juhl K, Guo L, Nishimura W, Dai X,
            Bonner-Weir S and Sharma A.
  TITLE     OVO homologue-like 1 (Ovol1) transcription factor: a novel target
            of neurogenin-3 in rodent pancreas
  JOURNAL   Diabetologia 53 (1), 115-122 (2010)
   PUBMED   19882138
  REMARK    GeneRIF: OVOL1 may play an important role in regulating the balance
            between proliferation and differentiation of pancreatic cells.
REFERENCE   3  (bases 1 to 2993)
  AUTHORS   Teng A, Nair M, Wells J, Segre JA and Dai X.
  TITLE     Strain-dependent perinatal lethality of Ovol1-deficient mice and
            identification of Ovol2 as a downstream target of Ovol1 in skin
            epidermis
  JOURNAL   Biochim Biophys Acta 1772 (1), 89-95 (2007)
   PUBMED   17049212
REFERENCE   4  (bases 1 to 2993)
  AUTHORS   Nair M, Bilanchone V, Ortt K, Sinha S and Dai X.
  TITLE     Ovol1 represses its own transcription by competing with
            transcription activator c-Myb and by recruiting histone deacetylase
            activity
  JOURNAL   Nucleic Acids Res 35 (5), 1687-1697 (2007)
   PUBMED   17311813
REFERENCE   5  (bases 1 to 2993)
  AUTHORS   Li B, Nair M, Mackay DR, Bilanchone V, Hu M, Fallahi M, Song H, Dai
            Q, Cohen PE and Dai X.
  TITLE     Ovol1 regulates meiotic pachytene progression during
            spermatogenesis by repressing Id2 expression
  JOURNAL   Development 132 (6), 1463-1473 (2005)
   PUBMED   15716349
REFERENCE   6  (bases 1 to 2993)
  AUTHORS   Dai X, Schonbaum C, Degenstein L, Bai W, Mahowald A and Fuchs E.
  TITLE     The ovo gene required for cuticle formation and oogenesis in flies
            is involved in hair formation and spermatogenesis in mice
  JOURNAL   Genes Dev 12 (21), 3452-3463 (1998)
   PUBMED   9808631
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473953.1.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_219513.3, XM_001070450.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMD00132271,
                              SAMD00132272 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2993
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q43"
     gene            1..2993
                     /gene="Ovol1"
                     /note="ovo like transcriptional repressor 1"
                     /db_xref="GeneID:309164"
                     /db_xref="RGD:1306956"
     exon            1..411
                     /gene="Ovol1"
                     /inference="alignment:Splign:2.1.0"
     CDS             312..1115
                     /gene="Ovol1"
                     /note="OVO homolog-like 1; ovo-like zinc finger 1;
                     ovo-like 1(Drosophila)"
                     /codon_start=1
                     /product="putative transcription factor Ovo-like 1"
                     /protein_id="NP_001101042.1"
                     /db_xref="GeneID:309164"
                     /db_xref="RGD:1306956"
                     /translation="MPRAFLVKKPCVSTCKRNWSELPDEERGEIYVPVSLGFCPPQPY
                     LEPEASVAEPPSCPLALDMSLRDSSYGVASGPCEVAQLPPEDVNHLTDPQSRDQGFLR
                     TKMKVTLGDSPNGDLFTCHICQKSFTYQRMLNRHMKCHNDVKRHLCTYCGKGFNDTFD
                     LKRHVRTHTGVRPYKCSLCDKAFTQRCSLESHLKKIHGVQQKYAYKERRAKLYVCEEC
                     GCTSESQEGHVLHLKEHHPDSPLLRKTSKKVAVALQNTVTSLLQGSPHL"
     exon            412..629
                     /gene="Ovol1"
                     /inference="alignment:Splign:2.1.0"
     exon            630..819
                     /gene="Ovol1"
                     /inference="alignment:Splign:2.1.0"
     exon            820..2993
                     /gene="Ovol1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gcacttgaag acttcgcgag cagccgcggg gacgccagtc tagctgaaag acgctcgctt
       61 agcgcttctc cgatcccggt gcacctgact gcacccgctc ggcggacacc ggcgaccttc
      121 ggcgtagttg gaaacgccac gcgtggtccc tggtacgctc tgtcctcaga acgtggacac
      181 gcctcggcga ctctttcctt gaactgtccc tattccggcg cctcaacccc gatccagtgg
      241 aagagaaggt gggacgacta cccgaactcg acttacggga gcgaaccgcg ccgggccagg
      301 aggaattgaa gatgccccgc gcgttcctgg tgaagaagcc atgcgtctcc acgtgcaaga
      361 ggaactggag cgagctcccg gacgaggagc gcggggagat ctacgtgcca gtcagcctcg
      421 gcttctgccc accgcagccc tacctcgaac cagaggcgtc agtggccgag cccccttctt
      481 gccccctggc tttggacatg agccttcgag actccagcta tggtgtggcc tcaggaccct
      541 gcgaggtggc tcagctgccc cctgaggatg tgaaccatct gacggatccc cagagcagag
      601 accagggctt cctacgaacc aagatgaagg tgaccttggg ggacagtcca aatggagacc
      661 tttttacctg tcacatctgc cagaagtcct tcacctacca gcgcatgctg aaccgacaca
      721 tgaagtgtca caatgatgtc aagaggcatc tctgcactta ctgtgggaag ggtttcaatg
      781 acacctttga cctcaagaga catgtccgaa cccacactgg tgtgaggccc tacaagtgca
      841 gtctgtgtga caaggccttc acccagcgct gctctctgga gtctcacctc aagaagatcc
      901 atggtgtgca gcagaagtat gcatataagg agcgccgggc caagctgtat gtgtgtgagg
      961 agtgtggctg cacttctgag agtcaggagg gccatgtcct gcacctcaag gaacaccacc
     1021 ctgacagccc actgctgcgc aagacctcca agaaggtggc tgtggctctg cagaacactg
     1081 tcacatccct gctgcaaggc agcccccatc tctgagcagc acaggctctg gaaggaccag
     1141 gttcacttcc tgctgctcag ccattcgcct tcctgcaacc tcttgctaga acaccagtga
     1201 tcgggaccag tgctccaccg cctcactcca ggcacactcg cacaattagg cactgacttc
     1261 cgctaggttt gggaagtctg tctttcgggc agagcccact ctgagcttgg gaccgtgggt
     1321 gcctgtgtcc aggcaggggt gaggccgaga aagtaaaaag agctgcggat agacacaggc
     1381 catttcactg cagcaggact ttgcagatgt gctgagaggg gatcccgagg acaagatgga
     1441 cgacggacgc ccatggagag cagaatcgag acaccagcag agagcacctg gcaaacaact
     1501 gcagtggtgg tgctggccgc agccctcatg ctcgcagggc tagcgctcag ggttccaggg
     1561 gctctctccc ctgcatcaga ggcccacctg tgaacagccg tgcgtgtgtg tgtgtgtgtg
     1621 tgtgtgtgtg tgtgtgtgtg tcacactgct ctctgtgatc tcttcacgtg tgtgtgtgca
     1681 ctcctgttct tcccacatat cacctcattc gtaagaagcc aacacaaggt gccaaggagg
     1741 ttttatttcc tttttttttt taaagatgac aaatgtacag atattaatat atttttggtg
     1801 cccacagtaa gactgtttag taagattaaa agggggagga gctggctttc tctccacccc
     1861 cattggttct atttatcctg gacatttcaa acctcctctg tgccttggtt ctggggtggt
     1921 tatgcagacc caccctgttc tctgagatgt ttcattaaag accttcctcc tgctccgccc
     1981 agcagatgga cagatggact gtccctcctg tccttcccct ggacagagtc tcgcctcttt
     2041 cccccctccc tggctccaca tccttctcag ggcctcagtt ttcctgctaa gcctgatgag
     2101 ccctgactgg gtgtggccca aggctgaggg tgggtcctac tgatggtctt caagcagatg
     2161 ggatggcgat ttgacaccaa gtccaagtcc acatctgagg ttctaaggta agggcaagaa
     2221 caggctggga gtctaggttt atttcttcgc taagtcaaaa attcttgagt agcagcaaaa
     2281 tttgagacag aataataatc cacataccag agactttgag agggagcatg taggcggcta
     2341 ataaagcttc tctgttgtct ttcttctgtt tcccaaatgc ctttgggccg agtggctccc
     2401 ctgaggaagt aggcctttgt ccactggtgt ttctgggtat cctgctgaga ccaaacaagg
     2461 gttgtgggtc aaagggtgta tgtctcacgc acccaaggag ttatagccga cctgcagggg
     2521 ttaagagacg cagacccgga acatggcggg ctgggaagcc cttgaatgcc caacagtccg
     2581 acctccctgc cttatgtgtg tagcacacag atgacacagg atctgacccc agcacgggct
     2641 ctcaagagaa cgaagtcaag tcttcctagg ctatctctga actccgtgtg gactgatctg
     2701 aagacttgtt taatgtttcc tcagcgtgtc tgggctactg cgctcttaag ttctcgaatg
     2761 taaaagtcac cacgactgga agcactgtgt tagatctgtg tctgttagct cattgccaat
     2821 ctggggctgt cataagcttt gtgttgtctg tcttgtttta taagctccta gccagccagt
     2881 aaagtgagag aactaatatt ttctgtactt ctgggttttt gttgtttgtg ttttcccctt
     2941 ggaccttttt tcttcatgca aagaaattca ttaaaacaac tgctgtttct tgc
//
