LOCUS       NM_001105851            2100 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus otopetrin 2 (Otop2), mRNA.
ACCESSION   NM_001105851 XM_001081682 XM_221107
VERSION     NM_001105851.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2100)
  AUTHORS   Tu,Y.H., Cooper,A.J., Teng,B., Chang,R.B., Artiga,D.J.,
            Turner,H.N., Mulhall,E.M., Ye,W., Smith,A.D. and Liman,E.R.
  TITLE     An evolutionarily conserved gene family encodes proton-selective
            ion channels
  JOURNAL   Science 359 (6379), 1047-1050 (2018)
   PUBMED   29371428
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473948.1.
            
            On or before Oct 3, 2007 this sequence version replaced
            XM_221107.4, XM_001081682.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: mixed sample support SAMD00132261, SAMD00132264
                              [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2100
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="10"
                     /map="10q32.1"
     gene            1..2100
                     /gene="Otop2"
                     /note="otopetrin 2"
                     /db_xref="GeneID:287820"
                     /db_xref="RGD:1304830"
     exon            1..83
                     /gene="Otop2"
                     /inference="alignment:Splign:2.1.0"
     exon            84..407
                     /gene="Otop2"
                     /inference="alignment:Splign:2.1.0"
     CDS             95..1786
                     /gene="Otop2"
                     /codon_start=1
                     /product="proton channel OTOP2"
                     /protein_id="NP_001099321.1"
                     /db_xref="GeneID:287820"
                     /db_xref="RGD:1304830"
                     /translation="MSEELVPHPNESLPGPRASPREVWKKGGRLLSVLLAVNVLLLAC
                     TLISGGAFNKVAVYDTDVFALLTTMMLLAALWIIFYLLRTARSPDAVPYRDAHAGPIW
                     LRGGLVLFGICTLVMDVFKTGYYSSFFECQSAIKILHPITQAVFVIVQTYFLWISAKD
                     CIHTHLDLTRCGLMFTLATNLAIWMTAVVDESVHQAHSFSGFHGNTSHTRLTPDSERA
                     GGTAEGDPCPCSTAICQIFQQGYFYLYPFNIEYSLFASTMLYVMWKNVGRLLASAHGH
                     GHTPSRVSLFRETFFAGPVLGLLLFVVGLAVFILYEVQVSGERGHTQQALVIYYSFNI
                     VCLGLMTLVSLSGSVIYRFDRRAMDHHKNPTRTLDVALLMGAALGQYAISYYSIVAVV
                     VGSPRDLLGALNLSHALLMIAQHTFQNVFIIESLHRGPPGAEPRETPPKELYQGITFA
                     NLSAIHTLPSCPPTPRLVSPNPEGPQEAVAIVSAPRCHWRRRCLKDISLFLLLCNVIL
                     WIMPAFGARPHFSNTVEVDFYGYSLWAAIVNICLPFGIFYRMHAVSSLLEVYVLS"
     exon            408..544
                     /gene="Otop2"
                     /inference="alignment:Splign:2.1.0"
     exon            545..603
                     /gene="Otop2"
                     /inference="alignment:Splign:2.1.0"
     exon            604..737
                     /gene="Otop2"
                     /inference="alignment:Splign:2.1.0"
     exon            738..1615
                     /gene="Otop2"
                     /inference="alignment:Splign:2.1.0"
     exon            1616..2100
                     /gene="Otop2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 caccggtcca gcccggcgtg ggagagagga gtcgcttgct gccccttgac ccccaacttg
       61 gtgtgggctc ccagtgcagc cagtcgcccc caccatgtcg gaagaactgg tcccgcatcc
      121 caatgagagc ctgccggggc ctcgagccag cccccgtgag gtgtggaaaa agggcggccg
      181 tctgctgtcg gtgctgttgg cggtcaacgt gctgctgctc gcctgcacgc tcatcagcgg
      241 cggggccttc aacaaggtgg ctgtgtatga caccgacgtg ttcgcgctgc tcaccaccat
      301 gatgctgctg gcagcgctgt ggataatctt ctacctcctc cgcaccgcgc gctctccaga
      361 cgcggtgcct taccgggatg ctcatgctgg ccccatctgg ctccgaggtg ggctggtgct
      421 gtttgggatt tgcacccttg tcatggatgt cttcaagact ggctactact ccagtttctt
      481 tgagtgccag tcggccatca agatcctgca ccccatcacc caagcggtgt ttgtcattgt
      541 ccagacttac tttctctgga tctcggctaa agactgtatc cacactcacc tggacctgac
      601 acggtgcggg ctcatgttca ccctcgccac caacctagcc atctggatga cagccgtagt
      661 ggatgagtcc gtgcaccagg cccactcctt cagtggcttc catggcaaca ccagccacac
      721 ccgcctcacc cctgactcag agcgtgccgg tggcaccgct gaaggagacc cgtgcccctg
      781 cagcacggcc atctgtcaga tcttccagca aggttacttc tacttgtatc ccttcaacat
      841 tgagtacagc ctctttgctt ccaccatgct gtacgtcatg tggaagaacg taggaaggct
      901 gctggcctcc gcccacggcc atggccacac accatccagg gtcagccttt tccgggagac
      961 cttttttgct ggccccgtct tgggcctgct cctctttgtg gtgggattgg ctgtcttcat
     1021 cctctatgag gtccaggtga gtggagagag aggccacacc cagcaggccc tggtcatcta
     1081 ttacagcttt aatattgtct gtctggggct catgactctg gtcagcctga gtggttcagt
     1141 catctaccgt tttgaccgtc gggccatgga ccatcataag aacccaacac ggaccctgga
     1201 tgtggccctg ctgatgggcg ccgccctggg ccagtatgcc atctcctact actctatcgt
     1261 ggctgtggtg gtgggctcac ccagagacct gctgggggca ctcaacctgt cccacgctct
     1321 actcatgatt gcccagcaca ccttccagaa cgtcttcatc atcgagagcc tccatcgggg
     1381 acctcctggg gctgagcctc gtgaaacgcc cccgaaggag ctctaccaag gcatcacctt
     1441 tgccaacctg agtgctatcc acaccttgcc ttcctgccca cccactccca ggcttgtcag
     1501 tcccaaccca gaaggccctc aggaagcggt ggctatcgtc tcagccccca ggtgccactg
     1561 gcgacgtcgg tgcctgaaag acatctctct gtttctcctg ctttgtaatg tcatcctgtg
     1621 gatcatgcct gccttcggcg cccgcccgca cttcagcaat accgtggagg tggactttta
     1681 tggttactcc ctctgggcgg ccatcgtcaa catctgcctg cctttcggca tcttctacag
     1741 aatgcacgcg gtctccagtc tgctggaggt ctacgtgctg tcctgaggct ccgagaaggg
     1801 gcagggcaga ggaaccccag aacccggaag gaaatcaggc tggcactcgc tccctgcctg
     1861 ccccagacta gaattttcac taaagtttat ttttccagga tgagttttta aatcaaaatc
     1921 gacatgccca tttattcctg catgacccta gagcttgggg agacccaagg cggggaaact
     1981 gctccccgta gcattctcta ggaccagaca ggatctggaa ataccatcac tgactctatc
     2041 tctaatccca gtcacatggc ctgtgtactc tctggagatg ggaccaataa acctgcaagt
//
