LOCUS       NM_138504               2355 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus oxidative stress induced growth inhibitor 1
            (Osgin1), mRNA.
ACCESSION   NM_138504
VERSION     NM_138504.2
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2355)
  AUTHORS   Ong,C.K., Ng,C.Y., Leong,C., Ng,C.P., Ong,C.S., Nguyen,T.T. and
            Huynh,H.
  TITLE     Structural characterization of three novel rat OKL38 transcripts,
            their tissue distributions, and their regulation by human chorionic
            gonadotropin
  JOURNAL   Endocrinology 145 (10), 4763-4774 (2004)
   PUBMED   15217983
  REMARK    GeneRIF: OKL38 may function as effector for human chorionic
            gonadotropin protection against mammary carcinogenesis.
            Availability of three rat OKL38 cDNAs may help to elucidate
            possible role of OKL38 in cellular growth, differentiation, and
            carcinogenesis.
REFERENCE   2  (bases 1 to 2355)
  AUTHORS   Huynh,H., Ng,C.Y., Ong,C.K., Lim,K.B. and Chan,T.W.
  TITLE     Cloning and characterization of a novel pregnancy-induced growth
            inhibitor in mammary gland
  JOURNAL   Endocrinology 142 (8), 3607-3615 (2001)
   PUBMED   11459809
REFERENCE   3  (bases 1 to 2355)
  AUTHORS   Sivaprasad,M., Iyer,K.S. and Venugopal,P.
  TITLE     Congenital asymptomatic absence of pericardium
  JOURNAL   Indian J Chest Dis Allied Sci 34 (3), 145-148 (1992)
   PUBMED   1302223
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AF549441.1.
            
            [WARNING] On Oct 16, 2024 this sequence was replaced by
            NM_138504.3.
            
            On Jun 9, 2003 this sequence version replaced NM_138504.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AF549441.1, BC091111.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760389
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: inferred from homology
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2355
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="Sprague-Dawley"
                     /db_xref="taxon:10116"
                     /chromosome="19"
                     /map="19q12"
     gene            1..2355
                     /gene="Osgin1"
                     /gene_synonym="Okl38"
                     /note="oxidative stress induced growth inhibitor 1"
                     /db_xref="GeneID:171493"
                     /db_xref="RGD:620679"
     exon            1..295
                     /gene="Osgin1"
                     /gene_synonym="Okl38"
                     /inference="alignment:Splign:2.1.0"
     exon            296..398
                     /gene="Osgin1"
                     /gene_synonym="Okl38"
                     /inference="alignment:Splign:2.1.0"
     exon            399..497
                     /gene="Osgin1"
                     /gene_synonym="Okl38"
                     /inference="alignment:Splign:2.1.0"
     exon            498..602
                     /gene="Osgin1"
                     /gene_synonym="Okl38"
                     /inference="alignment:Splign:2.1.0"
     CDS             536..1972
                     /gene="Osgin1"
                     /gene_synonym="Okl38"
                     /note="pregnancy-induced growth inhibitor"
                     /codon_start=1
                     /product="oxidative stress-induced growth inhibitor 1"
                     /protein_id="NP_612513.1"
                     /db_xref="GeneID:171493"
                     /db_xref="RGD:620679"
                     /translation="MSSWRHDSLRASSSDPLPVVIIGNGPSGICLSYLLSGYIPYVKP
                     GAVHPHPLLQRKLTEAPGVSILDQDLEYLSEGLEGRSQSPVALLFDALLRPDTDFGGS
                     LDSVLSWKRQKDRAIPHLVLGRNLPGGAWHSIEGSMVTLSQGQWMSLPDLQVKDWMRK
                     KCRGLRNSRATAGDIAHYYRDYVIKKGLSHNFVSGAVVTAVEWAKSEHCSPEAQAPSP
                     LFQVTGYLTAKDHSRQPFSLWAHNVVLATGTFDSPAMLGIPGETLPFVHHELSALEAA
                     LRAGTVNPTSDPVLIVGAGLSAADAVLFARHYNIQVIHAFRRSVHDPGLVFNQLPKML
                     YPEYHKVQQMMRDQSILSPSPYEGYRSLPEHQPLLFKEDRQAVFQDPQGGQQLFGVSM
                     VLVLIGSHPDLSYLPRAGADLAIDPSQPLSPKRNPIDVDPFTHESTQQEGLYALGPLA
                     GDNFVRFVQGGALAAASSLLKKETRKPP"
     exon            603..739
                     /gene="Osgin1"
                     /gene_synonym="Okl38"
                     /inference="alignment:Splign:2.1.0"
     exon            740..931
                     /gene="Osgin1"
                     /gene_synonym="Okl38"
                     /inference="alignment:Splign:2.1.0"
     exon            932..1023
                     /gene="Osgin1"
                     /gene_synonym="Okl38"
                     /inference="alignment:Splign:2.1.0"
     exon            1024..2337
                     /gene="Osgin1"
                     /gene_synonym="Okl38"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ctcagttggt agcgtgcttg tctagcatgc ctgcacccca gggtttcctc cccagcactg
       61 tataaatggg catgctgata caacaagcct gtgattccaa tacacaggag gtagagacag
      121 gagggtcaca agttcaaagt tctcctctgc tcccccaaga gtcagtacca gcctggggct
      181 acatgaaacc gttaagaaag gagtgagggc cagaggagca aggttcattt atccaatggc
      241 tgtttgattg aatatttgag gaggcactac tgcgtttcag gccctggacg ggcagaatct
      301 ctcactgagc ctggagtgca tgttccacca aacctggctg accagcaagt tcccctcagg
      361 atctccctgt ctctgctgcc acagtgctgg gatttcagca gggcactgtg agaaagtctc
      421 tcaccgtgac caagtttctc tgagtgtcca gccaacccag gctcaccagc tccctccagc
      481 taccgcccgt ccatcaggtc agctgccaac cccaggctga acaccaaccc cagctatgag
      541 ctcctggagg catgactccc tcagggccag cagctccgat cccctcccag tagttatcat
      601 tggcaatggt ccctcgggta tctgtctatc ctacctgctc tctggctaca tcccctatgt
      661 gaaaccagga gctgtccacc cgcaccccct gctgcagagg aagctgaccg aggctccagg
      721 ggtctccatc ttggatcagg acctagaata cctttccgaa ggcctcgaag gccgaagcca
      781 gagtcctgtg gccctgctct ttgatgccct cctacgtcct gacacagact ttggaggcag
      841 cctagactct gtgctctcct ggaagcggca gaaggaccgt gccattcccc accttgtcct
      901 gggacggaac ctccccgggg gtgcctggca ttccattgaa ggctccatgg tgactttgag
      961 ccaaggccag tggatgagtc tcccagacct gcaggtcaag gactggatgc ggaagaaatg
     1021 cagaggcctc cgtaacagca gagccacagc cggtgacatc gcccactact acagggacta
     1081 tgtgatcaag aagggtctca gtcacaactt tgtgtctggt gccgtggtca ctgccgtgga
     1141 atgggctaag tctgagcact gcagccctga ggcccaggca cccagccccc tcttccaagt
     1201 gacaggctac ctgactgcca aggaccacag ccgccagccc ttctcactgt gggcccataa
     1261 cgtggtcctg gccacgggca cctttgacag cccagccatg ctaggcatcc cgggagagac
     1321 cctgcctttt gtccaccacg agctgtcagc cctggaggcg gccctccggg caggcactgt
     1381 gaacccaacc tcagacccgg tgctgattgt gggagctggg ctatctgcgg ccgacgctgt
     1441 cctctttgcc cgtcactaca acatccaggt gatccatgcc tttcgccggt ctgtgcacga
     1501 ccctggcctg gtgttcaacc agctgcccaa gatgctgtac cccgagtacc acaaagtgca
     1561 gcagatgatg cgtgaccagt ccatcttgtc ccccagcccc tacgagggct accgcagcct
     1621 cccagagcac cagccactgc tcttcaagga agaccgtcag gcagtgttcc aggacccaca
     1681 ggggggccag cagctctttg gagtctccat ggtgctcgtc ctcatcggct cccaccccga
     1741 cctctcctac ctccctaggg caggggctga cctggccata gaccccagtc agccactgag
     1801 ccccaagagg aaccccatcg atgtggaccc gttcacccat gagagcactc aacaggaggg
     1861 cctgtatgcc ctagggcccc tggctgggga caactttgtg aggttcgtcc agggtggagc
     1921 cctggctgct gccagctccc tgctgaagaa ggagaccagg aagccacctt aacactagcc
     1981 tgatgctctg acacccaatc cctgaggagg aagagggctc accatagccc agtggcacat
     2041 gagcccgcct aaagattttc catgcgggga ccagtctccc ctgcaggagg ggaagacttg
     2101 agccccgtgg atgggggact atctgcccca gaggtatggg gaacacaggc cgccctatcc
     2161 tcaggcgagt caaggcccaa ggtgggagca gtagccatag accagagggg cctgggaccc
     2221 ctgaagctgt cggtgtgtgc tggagtcaca gggccagctg agtgtccaac taggaagacc
     2281 tcagacctaa cctttcacca tcagatctgc aataaaacca gctgtgcctc cactgcaaaa
     2341 aaaaaaaaaa aaaaa
//
