LOCUS       NM_201560               1566 bp    mRNA    linear   ROD 05-FEB-2024
DEFINITION  Rattus norvegicus oxidative stress responsive serine-rich 1
            (Oser1), mRNA.
ACCESSION   NM_201560 XM_215933
VERSION     NM_201560.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1566)
  AUTHORS   Vorontsova,I., Lam,L., Delpire,E., Lim,J. and Donaldson,P.
  TITLE     Identification of the WNK-SPAK/OSR1 signaling pathway in rodent and
            human lenses
  JOURNAL   Invest Ophthalmol Vis Sci 56 (1), 310-321 (2014)
   PUBMED   25515571
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1566)
  AUTHORS   Clerk,A., Kemp,T.J., Zoumpoulidou,G. and Sugden,P.H.
  TITLE     Cardiac myocyte gene expression profiling during H2O2-induced
            apoptosis
  JOURNAL   Physiol Genomics 29 (2), 118-127 (2007)
   PUBMED   17148688
REFERENCE   3  (bases 1 to 1566)
  AUTHORS   Puente,X.S. and Lopez-Otin,C.
  TITLE     A genomic analysis of rat proteases and protease inhibitors
  JOURNAL   Genome Res 14 (4), 609-622 (2004)
   PUBMED   15060002
REFERENCE   4  (bases 1 to 1566)
  AUTHORS   Shultz,M.A., Zhang,L., Gu,Y.Z., Baker,G.L., Fannuchi,M.V.,
            Padua,A.M., Gurske,W.A., Morin,D., Penn,S.G., Jovanovich,S.B.,
            Plopper,C.G. and Buckpitt,A.R.
  TITLE     Gene expression analysis in response to lung toxicants: I.
            Sequencing and microarray development
  JOURNAL   Am J Respir Cell Mol Biol 30 (3), 296-310 (2004)
   PUBMED   12947022
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AJ621831.1 and CF113276.1.
            
            [WARNING] On May 7, 2024 this sequence was replaced by NM_201560.3.
            
            On Nov 16, 2007 this sequence version replaced NM_201560.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AJ621831.1, EV777265.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132300, SAMEA5760383
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1552              AJ621831.1         5-1556
            1553-1560           CF113276.1         156-163
            1561-1566           AJ621831.1         1566-1571
FEATURES             Location/Qualifiers
     source          1..1566
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="Sprague-Dawley"
                     /db_xref="taxon:10116"
                     /chromosome="3"
                     /map="3q42"
     gene            1..1566
                     /gene="Oser1"
                     /gene_synonym="osr1; Perit1; RGD1303142"
                     /note="oxidative stress responsive serine-rich 1"
                     /db_xref="GeneID:296346"
                     /db_xref="RGD:1303142"
     exon            1..80
                     /gene="Oser1"
                     /gene_synonym="osr1; Perit1; RGD1303142"
                     /inference="alignment:Splign:2.1.0"
     exon            81..201
                     /gene="Oser1"
                     /gene_synonym="osr1; Perit1; RGD1303142"
                     /inference="alignment:Splign:2.1.0"
     CDS             125..1000
                     /gene="Oser1"
                     /gene_synonym="osr1; Perit1; RGD1303142"
                     /note="oxidative stress responsive 1; oxidative
                     stress-responsive protein 1; peroxide-inducible transcript
                     1 protein"
                     /codon_start=1
                     /product="oxidative stress-responsive serine-rich protein
                     1"
                     /protein_id="NP_963854.1"
                     /db_xref="GeneID:296346"
                     /db_xref="RGD:1303142"
                     /translation="MKSEAKDGEEESLQTAFKKLRVDASGSIVSLSVGEGTSVRASVR
                     TTVDDTKPKTMCAPKDSWHGSTRKSSRGAVRIQRRRRSKSPVLHPPKFIHCSTTASPS
                     SSQLKQRSQTEPLDGSSGRGISTPKEFSTGENSTSLDINHTGAAIEPLRSSVLRLPSE
                     SKTEELSDATQVSPESLTANDLSDFQSVSKLSQGKPCVCVGKACQCKRWHDMEVYSFS
                     GLQNVPPLAPERRSLEDYSQSLHTRTLSGSPRSCSEQARVYVDDVTIEDLAGYMEYYL
                     YIPKKMSHMAEMMYT"
     exon            202..315
                     /gene="Oser1"
                     /gene_synonym="osr1; Perit1; RGD1303142"
                     /inference="alignment:Splign:2.1.0"
     exon            316..1566
                     /gene="Oser1"
                     /gene_synonym="osr1; Perit1; RGD1303142"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gtcagtcagg cgcggcggtc gcggagagac gctcggagcc gtcggggccg ggttcccggg
       61 agcgccccag ctgcgaggag tattaacggg agggaacatc aataggagta cagaagcctt
      121 cacaatgaaa tctgaagcca aggatggaga ggaggaaagc ctgcaaactg ccttcaagaa
      181 attaagagtg gacgcatcag ggtccatcgt atctctgtct gttggagaag gcacaagtgt
      241 cagagcgtca gtcagaacaa cagtagatga caccaaaccg aaaaccatgt gtgcacctaa
      301 ggacagttgg catgggtcta caaggaagtc ttcacgagga gcagtgagaa tccagcgtcg
      361 tagacgctct aagtctcctg ttcttcatcc tcccaagttc atacattgca gtacaacagc
      421 atctccctcc agcagccagc ttaagcagag aagccagact gagccactgg atggcagcag
      481 tggacgggga atttcaacac ccaaagagtt cagcacagga gaaaactcta cttctcttga
      541 tattaaccac acaggagcag ccatcgagcc tctgagaagt tccgttctga ggctcccatc
      601 agagagtaaa acagaagagc tctctgatgc tacccaagtc tccccagaaa gtcttacggc
      661 caacgatctc tctgactttc aatctgtttc caagctaagc cagggcaagc catgtgtgtg
      721 tgtaggcaag gcgtgccagt gtaagaggtg gcacgatatg gaagtgtatt ccttttcagg
      781 tctgcagaat gtccctcctt tggccccaga acgaagatca cttgaggact actctcagtc
      841 actgcacacc agaactctgt ctggctctcc tcgatcctgt tccgagcaag ctcgtgtcta
      901 tgtggatgat gtgaccattg aggacctagc aggctacatg gagtattact tgtatatccc
      961 taagaaaatg tcccacatgg cagagatgat gtacacctga taacaagaag ctaattcatg
     1021 tgctttaaac caatgaaagg ttgtcagagg tttagttaac ggcagacccg gtggccactc
     1081 tgtgagaaga catctctttc tgctcactgt gcttgcaata aaaactattc ttggcatctc
     1141 agttaatctt cattctgtca gtttactgag ttcttacgta cctgtcaagg caagcaggtc
     1201 aatgaaaatc tctcctaaaa atgttctgag ggctgaagaa accataatga ctggagactg
     1261 gcagcagtgg ggacatggtg aaatccttat aagacagcat atttcagacc tgcttacagt
     1321 gtggcagcaa gaaactcaaa tgtgcttttg taaccgaact gaacacttgt cgtgtagatg
     1381 ccagcccatc agtagtagag ctttaagact cacctaaact gtctttggtt taacacgggt
     1441 ttgtcattaa aggtttttat gttactgttg agtcagatct aaggtttaga ttcagtttga
     1501 ataaaccagg tggcctgtcc tatattgttt gagggaatca ttaaccttac tgtcactaaa
     1561 taaacc
//
