LOCUS       NM_001107044            3504 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus oxysterol binding protein-like 7 (Osbpl7), mRNA.
ACCESSION   NM_001107044 XM_001081327 XM_220915
VERSION     NM_001107044.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3504)
  AUTHORS   Loilome,W., Wechagama,P., Namwat,N., Jusakul,A., Sripa,B., Miwa,M.,
            Kuver,R. and Yongvanit,P.
  TITLE     Expression of oxysterol binding protein isoforms in
            opisthorchiasis-associated cholangiocarcinoma: a potential
            molecular marker for tumor metastasis
  JOURNAL   Parasitol Int 61 (1), 136-139 (2012)
   PUBMED   21763455
REFERENCE   2  (bases 1 to 3504)
  AUTHORS   Zhong,W., Zhou,Y., Li,S., Zhou,T., Ma,H., Wei,K., Li,H.,
            Olkkonen,V.M. and Yan,D.
  TITLE     OSBP-related protein 7 interacts with GATE-16 and negatively
            regulates GS28 protein stability
  JOURNAL   Exp Cell Res 317 (16), 2353-2363 (2011)
   PUBMED   21669198
REFERENCE   3  (bases 1 to 3504)
  AUTHORS   Suchanek,M., Hynynen,R., Wohlfahrt,G., Lehto,M., Johansson,M.,
            Saarinen,H., Radzikowska,A., Thiele,C. and Olkkonen,V.M.
  TITLE     The mammalian oxysterol-binding protein-related proteins (ORPs)
            bind 25-hydroxycholesterol in an evolutionarily conserved pocket
  JOURNAL   Biochem J 405 (3), 473-480 (2007)
   PUBMED   17428193
REFERENCE   4  (bases 1 to 3504)
  AUTHORS   Lehto,M., Tienari,J., Lehtonen,S., Lehtonen,E. and Olkkonen,V.M.
  TITLE     Subfamily III of mammalian oxysterol-binding protein (OSBP)
            homologues: the expression and intracellular localization of ORP3,
            ORP6, and ORP7
  JOURNAL   Cell Tissue Res 315 (1), 39-57 (2004)
   PUBMED   14593528
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473948.1.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_001081327.1, XM_220915.4.
            
            ##Evidence-Data-START##
            RNAseq introns :: partial sample support SAMD00132266, SAMD00132279
                              [ECO:0000350]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..3504
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="10"
                     /map="10q31"
     gene            1..3504
                     /gene="Osbpl7"
                     /note="oxysterol binding protein-like 7"
                     /db_xref="GeneID:303497"
                     /db_xref="RGD:1309141"
     exon            1..137
                     /gene="Osbpl7"
                     /inference="alignment:Splign:2.1.0"
     exon            138..289
                     /gene="Osbpl7"
                     /inference="alignment:Splign:2.1.0"
     CDS             215..2674
                     /gene="Osbpl7"
                     /codon_start=1
                     /product="oxysterol-binding protein-related protein 7"
                     /protein_id="NP_001100514.1"
                     /db_xref="GeneID:303497"
                     /db_xref="RGD:1309141"
                     /translation="MDFQERDTPSLAESTQSSKPSSTQQASELWEVVEEPRGRLGAED
                     IMPERQEGHLLKKRKWPLKGWHKITKGKVHGSIDVRLSVMSINKKAQRIDLDTEDNIY
                     HLKIKSQDLFQSWVSQLRAHRLAQRSDLPNATHRKAPGTQTLTAGSASALPGVGPREK
                     VSSWLRDSDGLDRCSHALSECQGKLQELHRLLQSLESLHRIPSAPVIPTHQASVTTER
                     PKKGKRTSRMWCTQGFAKDDTIGRVGRLHGSVPNLSRYLESRDTSGPRGLPPPDYAHL
                     QRSFWALAQKVHNSLSSVLVALTTERDRLRDLHQGSELSRMAVSEAPDGQRRLHSLSI
                     SSDTTADSFSSLNPEEQEALYRKGRELTPQLSQSSVLSLADSHTEFFDACEVLLSASS
                     SENEGSEEEESCASEITTSLSEEVLDIRGADRYPKGACVPGIAVGPPRRRCLPAASGP
                     GTDVSLWNILRNNIGKDLSKVSMPVQLNEPLNTLQRLCEELEYSSLLDQASRMADPCE
                     RMVYIAAFAVSAYSSTYHRAGCKPFNPVLGETYECERPDRGFRFISEQVSHHPPISAC
                     HAESENFIFWQDMKWKNKFWGKSLEIVPVGTVNVSLPRFGDHFEWNKVTSCIHNILSG
                     QRWIEHYGEVLIRNTQDSSCHCKITFCKAKYWSSNIHEVQGAVLSRSGRVLHRLFGKW
                     HEGLYRGPPPGGQCIWKPNSMPPDHERNFGFTQFALELNELTAELKRTLPSTDTRLRP
                     DQRYLEEGNIQAAEAQKRRIEQLQRDRRRVMEENNIVHQARFFRRQTDSSGKEWWVTN
                     HTYWRLRAEPGYGNLDGAVLW"
     exon            290..415
                     /gene="Osbpl7"
                     /inference="alignment:Splign:2.1.0"
     exon            416..529
                     /gene="Osbpl7"
                     /inference="alignment:Splign:2.1.0"
     exon            530..625
                     /gene="Osbpl7"
                     /inference="alignment:Splign:2.1.0"
     exon            626..743
                     /gene="Osbpl7"
                     /inference="alignment:Splign:2.1.0"
     exon            744..847
                     /gene="Osbpl7"
                     /inference="alignment:Splign:2.1.0"
     exon            848..940
                     /gene="Osbpl7"
                     /inference="alignment:Splign:2.1.0"
     exon            941..1073
                     /gene="Osbpl7"
                     /inference="alignment:Splign:2.1.0"
     exon            1074..1168
                     /gene="Osbpl7"
                     /inference="alignment:Splign:2.1.0"
     exon            1169..1264
                     /gene="Osbpl7"
                     /inference="alignment:Splign:2.1.0"
     exon            1265..1402
                     /gene="Osbpl7"
                     /inference="alignment:Splign:2.1.0"
     exon            1403..1496
                     /gene="Osbpl7"
                     /inference="alignment:Splign:2.1.0"
     exon            1497..1744
                     /gene="Osbpl7"
                     /inference="alignment:Splign:2.1.0"
     exon            1745..1882
                     /gene="Osbpl7"
                     /inference="alignment:Splign:2.1.0"
     exon            1883..1946
                     /gene="Osbpl7"
                     /inference="alignment:Splign:2.1.0"
     exon            1947..2025
                     /gene="Osbpl7"
                     /inference="alignment:Splign:2.1.0"
     exon            2026..2170
                     /gene="Osbpl7"
                     /inference="alignment:Splign:2.1.0"
     exon            2171..2315
                     /gene="Osbpl7"
                     /inference="alignment:Splign:2.1.0"
     exon            2316..2442
                     /gene="Osbpl7"
                     /inference="alignment:Splign:2.1.0"
     exon            2443..2565
                     /gene="Osbpl7"
                     /inference="alignment:Splign:2.1.0"
     exon            2566..3504
                     /gene="Osbpl7"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cggctgctgc tgctgctgct gctgctgctg ctgctgctgc tgctcagctc tgtgaagagg
       61 tagctggtga ctcggagact gtctcagagg cacatcagca tacggaccaa gaagcactga
      121 cgttcatgga gcctgggggt ccccccagga caaggtgaca ttctccccat cccactctgc
      181 tctgctgtcc tcaccaggga ataacttctt cctcatggac ttccaggaaa gagacactcc
      241 ctccctggct gagagtactc agtcttcaaa gcccagcagt acccagcagg cctccgagct
      301 gtgggaggtg gtggaggagc ctcggggcag gctgggagca gaagacatca tgcctgagag
      361 acaggaagga cacctgctca agaagaggaa gtggcctctt aagggctggc acaagatcac
      421 caaggggaag gttcatggct ccatcgatgt ccggctatcc gtcatgtcca tcaacaaaaa
      481 ggcccagcgc attgacctcg acacagaaga caacatttac cacctaaaga tcaaatctca
      541 ggacctgttc caaagctggg tgtctcagct tcgagcccac cgtttggccc agcgctcgga
      601 cctgcccaat gccactcacc ggaaggctcc tggcacccag acgctaacag caggcagtgc
      661 ctcagcctta cctggggttg gacctcgaga gaaagtgtca tcctggctga gggacagtga
      721 tgggctagac cgatgttctc atgcgctgtc agaatgccag ggtaagctgc aggaactaca
      781 cagactcctt cagagcctgg agtccctaca cagaatcccc tccgcccctg tgatccccac
      841 acaccaggcc tcagtgacga ccgagagacc caagaagggg aaacggacca gccgcatgtg
      901 gtgcacacag ggctttgcca aggatgacac cattggacgg gttggccgtc tgcatggctc
      961 tgttcccaac ctgtctcgtt acctggaatc tcgggacact tctggcccac gtggcctgcc
     1021 acctccggac tatgcccatt tacagcgcag tttctgggct ctggcccaga aggtgcacaa
     1081 ctccctcagc agtgtcctgg ttgccctcac cacagaacgg gaccgactga gagacctgca
     1141 ccagggctca gagttgtcaa ggatggcggt ttctgaggct ccggatggtc agagacgtct
     1201 ccactcactc tccatatcct cagacaccac agcagactcc ttcagttccc tgaacccgga
     1261 ggagcaagaa gctctgtaca ggaaaggccg ggagctgacc ccccagctgt cccagagcag
     1321 cgtgctgtcc ctcgctgact cccacaccga gttctttgat gcctgtgagg tgctcctctc
     1381 tgccagttct tctgagaatg agggttctga ggaggaagag tcatgtgcta gtgagatcac
     1441 caccagcctg tctgaagagg tcctggacat caggggagct gaccgctatc caaaaggggc
     1501 ctgtgttcca gggattgccg tagggccccc tcgacgccgc tgcttgccag ctgccagtgg
     1561 gcccgggaca gacgtgagcc tgtggaatat cctccgcaac aatatcggca aagacctgtc
     1621 caaggtgtcg atgcccgtgc agctcaacga gccgctcaac acgctgcaga ggctctgcga
     1681 ggagctggag tacagcagcc tcctggacca ggccagccgc atggctgacc cctgcgagcg
     1741 catggtatac atcgcagcct ttgctgtctc tgcctactcc tccacgtacc accgggcggg
     1801 atgcaagccc ttcaacccgg tcctgggaga gacctacgag tgtgagcggc ctgaccgggg
     1861 tttccgtttt atcagcgagc aggtctccca tcatcccccg atctccgcgt gtcatgcaga
     1921 atctgagaac ttcatcttct ggcaagacat gaaatggaag aacaagttct ggggcaaatc
     1981 cctggagatc gtgcccgtgg ggacagtcaa tgtcagcctg cccaggtttg gggatcactt
     2041 tgagtggaac aaggtaacgt cctgtattca caacatcctg agtggccagc gctggatcga
     2101 gcattacgga gaagtgctta tccgaaatac acaagatagc tcttgccact gcaaaatcac
     2161 cttttgcaag gccaagtact ggagttctaa catccatgag gtacaaggtg cggtgcttag
     2221 caggagtggc cgcgtcctcc accgcctctt cgggaagtgg catgagggac tgtaccgagg
     2281 ccccccaccg ggtgggcagt gcatttggaa acccaactcg atgcccccag accatgagcg
     2341 aaacttcggg ttcacgcagt ttgccctgga gttgaatgag ctgacggcag agctgaagag
     2401 gacgctgcct tccactgaca cacggctacg gcctgaccag agatacctgg aggaggggaa
     2461 catacaggcc gctgaggccc agaagagaag gatagagcag ctacagcgcg atcggagaag
     2521 agtaatggag gaaaacaaca tagtccacca ggcgcgcttc ttcaggcgac agacagacag
     2581 cagcggcaag gagtggtggg tgaccaacca tacatactgg aggctacgcg ctgagccagg
     2641 ctatgggaac ctggatgggg ctgtgctctg gtaaccctgg cctcggggca ggagactcta
     2701 gctcatcact cctgccccag ctcctgctat ggacatgtgg gtgaggtcgg gctccctctc
     2761 gctgcccttg agtgccaagg ggcagcctag gctccagccc tttccccctc tgctggccag
     2821 aggggttgta tctcagcaca gtcccgttcc accgctggga tggaagtgga gtctgtgttc
     2881 cccccacccc ccgtcttgtt accccaagtc tggcgtgtca gacccttctc gctcagccac
     2941 cctcctcctc tgggagcgtt tgggagggat gccagtttcc ccagatccgt cccccatttc
     3001 agtgccttcc ttggacacag agggcccctt gatgctaccc agacttcccg tgcccagggt
     3061 gttgcctgtg ttggctgtgt tggagtgagt gaaggacagg agatgcctcc tttcccatct
     3121 gtcctccctt cagcatcttc cctgtgccct gacccatccc ttgtcctgca tccccttctc
     3181 ccaaactgca aagcaccttt ggcttccggc tcctccatcc ctgctccacc agtggtcccc
     3241 tcaggctcag cttagcaaaa gtcccaagag gtggagagca gtctggggtg cctggtctca
     3301 gatccaccca ggagggagtg agccagtgtg agcgtacgtt tgtgtaggag tgtgtgtgtg
     3361 tcctgctcgc cggcgagcag gcttcctcat gtagccagga cacctccgct gttgctggtg
     3421 tctgttacag ttgctgctca atttcccagt ttgcctgagt caggtgaatt gctatgacat
     3481 tccaagctcc aataaagact gtcc
//
