LOCUS       NM_001107735            4038 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus oxysterol binding protein-like 6 (Osbpl6), mRNA.
ACCESSION   NM_001107735 XM_001062227 XM_242057
VERSION     NM_001107735.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 4038)
  AUTHORS   Ouimet,M., Hennessy,E.J., van Solingen,C., Koelwyn,G.J.,
            Hussein,M.A., Ramkhelawon,B., Rayner,K.J., Temel,R.E., Perisic,L.,
            Hedin,U., Maegdefessel,L., Garabedian,M.J., Holdt,L.M., Teupser,D.
            and Moore,K.J.
  TITLE     miRNA Targeting of Oxysterol-Binding Protein-Like 6 Regulates
            Cholesterol Trafficking and Efflux
  JOURNAL   Arterioscler Thromb Vasc Biol 36 (5), 942-951 (2016)
   PUBMED   26941018
REFERENCE   2  (bases 1 to 4038)
  AUTHORS   Lehto,M., Tienari,J., Lehtonen,S., Lehtonen,E. and Olkkonen,V.M.
  TITLE     Subfamily III of mammalian oxysterol-binding protein (OSBP)
            homologues: the expression and intracellular localization of ORP3,
            ORP6, and ORP7
  JOURNAL   Cell Tissue Res 315 (1), 39-57 (2004)
   PUBMED   14593528
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473949.1.
            
            [WARNING] On Jul 19, 2024 this sequence was replaced by
            NM_001107735.2.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_001062227.1, XM_242057.4.
FEATURES             Location/Qualifiers
     source          1..4038
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="3"
                     /map="3q24"
     gene            1..4038
                     /gene="Osbpl6"
                     /note="oxysterol binding protein-like 6"
                     /db_xref="GeneID:311129"
                     /db_xref="RGD:1308887"
     exon            1..55
                     /gene="Osbpl6"
                     /inference="alignment:Splign:2.1.0"
     exon            56..205
                     /gene="Osbpl6"
                     /inference="alignment:Splign:2.1.0"
     exon            206..442
                     /gene="Osbpl6"
                     /inference="alignment:Splign:2.1.0"
     exon            443..698
                     /gene="Osbpl6"
                     /inference="alignment:Splign:2.1.0"
     CDS             597..3401
                     /gene="Osbpl6"
                     /codon_start=1
                     /product="oxysterol-binding protein-related protein 6"
                     /protein_id="NP_001101205.1"
                     /db_xref="GeneID:311129"
                     /db_xref="RGD:1308887"
                     /translation="MSSDEKGISPAHKTSTPTHRSALSSTSSQRESRQSIHVLERTAS
                     SSTEPSISRQLLEPEPIPLSKEADSWEIIEGLKIGQTNVQKPDRHEGFMLKKRKWPLK
                     GWHKRFFVLDNGMLKYSKAPLDIQKGKVHGSIDVGLSVMSIKKKARRIDLDTEEHIYH
                     LKVKSQDWFDAWVSKLRHHRLYRQNEIVRSPRDASFHIFPATSTAESSPAANVSVVDG
                     KMQPSSFPWQSPLPCSNSLPATCTTGQSKVAAWLQDSEEMDRCAEDLAHCQSNLVELS
                     KLLQNLEILQRTQSAPNFTDMQANCVDISKKDKRVTRRWRTKSVSKDTKIQLQVPFSA
                     TMSPVRLHSSNPNLCADIEFQTPPSHLTDPLESSTDYTKLQEEFCLIAQKVHSLLKSA
                     FNSIAIEKEKLKQMVSEQDHNKGHSTQMARLRQSLSQALNQNAELRSRLNRIHSESTI
                     CDHVVSVNIIPSPDEPGEQIHANLPLSQQVVNESRLSMSESVSEFFDAQEVLLSASSS
                     ENEASDDESYISDVSDNISEDNTSVADNISRQILNGELTGGAFRNGRRTCLPAPCPDT
                     SNINLWNILRNNIGKDLSKVSMPVELNEPLNTLQHLCEEMEYSELLDKASETDDPYER
                     MVLVAAFAVSGYCSTYFRAGSKPFNPVLGETYECIREDKGFRFFSEQVSHHPPISACH
                     CESKNFVFWQDIRWKNKFWGKSMEILPVGTLNVTLPKYGDYYVWNKVTTCIHNILSGR
                     RWIEHYGEVTIRNTKSSVCICKLTFVKVNYWNSNVNEVQGVVIDQEGKVVHRLFGKWH
                     EGLYCGVAPSAKCIWRPGSLPTNYELYYGFTRFAVELNELDPVLKELLPPTDARFRPD
                     QRFLEEGNLEAAAAEKQRVEELQRSRRRYMEENNLEHIPKFFKKVIDANQREAWVSND
                     TYWELRKDPGFSKVDSPVLW"
     exon            699..791
                     /gene="Osbpl6"
                     /inference="alignment:Splign:2.1.0"
     exon            792..914
                     /gene="Osbpl6"
                     /inference="alignment:Splign:2.1.0"
     exon            915..968
                     /gene="Osbpl6"
                     /inference="alignment:Splign:2.1.0"
     exon            969..1082
                     /gene="Osbpl6"
                     /inference="alignment:Splign:2.1.0"
     exon            1083..1253
                     /gene="Osbpl6"
                     /inference="alignment:Splign:2.1.0"
     exon            1254..1386
                     /gene="Osbpl6"
                     /inference="alignment:Splign:2.1.0"
     exon            1387..1490
                     /gene="Osbpl6"
                     /inference="alignment:Splign:2.1.0"
     exon            1491..1583
                     /gene="Osbpl6"
                     /inference="alignment:Splign:2.1.0"
     exon            1584..1749
                     /gene="Osbpl6"
                     /inference="alignment:Splign:2.1.0"
     exon            1750..1883
                     /gene="Osbpl6"
                     /inference="alignment:Splign:2.1.0"
     exon            1884..1991
                     /gene="Osbpl6"
                     /inference="alignment:Splign:2.1.0"
     exon            1992..2129
                     /gene="Osbpl6"
                     /inference="alignment:Splign:2.1.0"
     exon            2130..2217
                     /gene="Osbpl6"
                     /inference="alignment:Splign:2.1.0"
     exon            2218..2471
                     /gene="Osbpl6"
                     /inference="alignment:Splign:2.1.0"
     exon            2472..2609
                     /gene="Osbpl6"
                     /inference="alignment:Splign:2.1.0"
     exon            2610..2673
                     /gene="Osbpl6"
                     /inference="alignment:Splign:2.1.0"
     exon            2674..2752
                     /gene="Osbpl6"
                     /inference="alignment:Splign:2.1.0"
     exon            2753..2897
                     /gene="Osbpl6"
                     /inference="alignment:Splign:2.1.0"
     exon            2898..3042
                     /gene="Osbpl6"
                     /inference="alignment:Splign:2.1.0"
     exon            3043..3169
                     /gene="Osbpl6"
                     /inference="alignment:Splign:2.1.0"
     exon            3170..3292
                     /gene="Osbpl6"
                     /inference="alignment:Splign:2.1.0"
     exon            3293..4038
                     /gene="Osbpl6"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gtgtgaatca gcaatgtgaa cactggggag gtcagtggtc atgtcttcgc agtcggttct
       61 tactgggaag ccaataaaag aagacagtta aggcaccagc agtgccagcg gggctgacag
      121 actgcagcaa aagaacagag gccaggccac tgagaagcag ttgtaatggt acagccaagc
      181 tagaagactc tgacacgagg caaaggcctc ctgtagaagg tgtggctgag attaaaggtg
      241 tgtgcctcat gcctggatct ggaacttgct ctgtcccagg ctggcctgga attcagagat
      301 tgcttgcctc agtctcatga gactaaaggc atctattacc ttgcctagac ctgaggtttt
      361 catggtcaca tgcctcaaga tctagatcaa cagcatgtcc caggtcagaa gcgtgtgtct
      421 tggagcctca ggatcatcat aagaagtttg gacacatcat cagtggccag agctttccga
      481 gtctcgtccg atccgaggga gatggactga agccacagac tgtctggttc tttgtctggg
      541 agttggaagg aggattggga tggtctcacg tgcacatccc tagactaatt gcaaccatga
      601 gttcagacga gaagggcata tcccctgctc ataaaacatc cactccgacc cacagaagtg
      661 ccttgtcgtc aacatcttct cagagggaaa gcagacagag catccacgtt ctggagagaa
      721 ctgcttcatc cagcacggag ccctccatca gtcggcagct gctagagccg gagcccatcc
      781 ccctctccaa ggaagctgac agctgggaaa ttatagaagg gctgaaaata ggccaaacca
      841 atgtccagaa accagacagg cacgagggat ttatgctgaa gaagagaaaa tggcctttaa
      901 agggctggca caagcgcttc tttgtcctgg ataacggaat gttaaagtat tcaaaggcgc
      961 cacttgacat ccaaaaaggg aaagtccacg ggagcataga tgtaggactg tctgtcatgt
     1021 cgattaaaaa gaaggctcgg agaatagacc tcgacacaga ggagcacatc tatcatttga
     1081 aggtgaaatc ccaggactgg tttgatgcct gggtctccaa actgcgccac cacaggttgt
     1141 accgtcagaa tgaaatcgtg aggtcaccga gagacgccag tttccacata tttcctgcaa
     1201 cgtcaacagc tgagtcctcc ccagccgcta atgtctctgt tgtggatgga aagatgcagc
     1261 ctagcagctt tccatggcag tcccccttac catgcagtaa cagcctccct gcgacctgca
     1321 cgactgggca gagtaaggtg gcagcctggc tgcaggactc agaagaaatg gaccggtgtg
     1381 cggaagatct tgcacattgc cagtcaaacc ttgtggaact tagcaagctc ctgcagaacc
     1441 tggagatact tcagagaact cagtcggctc ctaacttcac tgacatgcag gctaactgtg
     1501 tagatatttc aaagaaagac aagcgggtca caagacgctg gaggacaaaa agtgtcagca
     1561 aagatacaaa aatacaactg caggttcctt tcagcgccac catgtcaccc gtgcgtctgc
     1621 actcctccaa ccccaacctt tgtgcagaca ttgagtttca gacccctcct agccacctca
     1681 ccgaccctct ggaaagttcc acagattata ccaagctaca agaagaattt tgtctaattg
     1741 cgcagaaagt gcattctctt ctgaagtctg cgtttaacag catagctata gagaaggaga
     1801 agctgaagca gatggtttcg gagcaagatc acaacaaagg ccacagcaca cagatggcca
     1861 ggctccgaca gtcgctgtca caggcactta accagaacgc tgagctccgg agtcgactga
     1921 acagaataca ctcggagtct accatttgtg atcacgttgt cagtgtaaat attatcccta
     1981 gccctgatga gcctggtgag cagatccacg ccaacctccc cctgtcacag caggtggtca
     2041 acgagagccg cctctccatg tcggaatccg tgtcagagtt cttcgatgcc caagaggtgc
     2101 tcctgtctgc gagttcatcg gagaatgagg cttccgatga cgagtcctac atcagcgacg
     2161 tgagtgacaa catatctgag gacaacacca gtgtcgccga caacatttct cggcaaatcc
     2221 tgaatgggga gctcacagga ggcgccttcc gcaatggccg tcgaacctgc ctgcctgctc
     2281 cttgcccgga cactagtaac attaacctgt ggaatatctt gaggaacaac attggcaaag
     2341 acctgtccaa agtctccatg cccgtggagc tcaacgagcc actcaacact ctgcagcacc
     2401 tctgtgagga aatggagtac agtgagctcc tggacaaagc ctcggagacc gacgacccct
     2461 atgagaggat ggttctcgtc gctgcctttg cagtctcagg gtactgttcc acctacttca
     2521 gagcaggaag taagccgttc aatccggtcc tgggggagac ctatgagtgc ataagagaag
     2581 ataaggggtt tcggttcttc tcggaacaag ttagccatca tccacccatt tctgcctgtc
     2641 actgtgaatc caagaacttt gtgttttggc aagatatcag atggaaaaat aaattctggg
     2701 gaaagtcaat ggaaatcctg cccgtcggaa ccctgaatgt cacgcttcca aagtacggag
     2761 attactatgt gtggaataaa gtcaccacgt gtatacataa catcctcagt gggaggagat
     2821 ggatcgagca ttacggcgaa gtaaccatta gaaataccaa aagcagtgtt tgcatttgca
     2881 agctcacatt cgtcaaggtg aattactgga actccaacgt gaatgaagtc cagggggtgg
     2941 tgatagacca ggaggggaag gtggtgcacc gactgtttgg gaagtggcac gaaggactct
     3001 actgcggggt ggccccctcg gcaaagtgca tctggagacc aggttctctg ccaaccaact
     3061 atgagctcta ctatggcttt acgaggtttg ccgtggagct caacgagttg gatccagtcc
     3121 ttaaggagct ccttcctccc acagatgccc gattccggcc agatcaaaga tttttggaag
     3181 aagggaacct agaagctgca gctgcagaga aacaaagagt tgaggaactc cagagatcga
     3241 gaagacgcta catggaggaa aacaatcttg agcacatacc aaaatttttt aaaaaagtta
     3301 ttgacgcaaa tcaaagagaa gcctgggttt ctaacgacac ctactgggaa cttcgaaagg
     3361 accctgggtt tagcaaagta gacagccctg ttctttggta aactggagac gtagagctag
     3421 ccaatacacc acactcggaa tgaataacta tgcacaatta tgtttcttat agctacgcgt
     3481 ggtttctggg tcgactgaaa acctcccatt tgcttttcta ttcatcttta taatggattt
     3541 tcaaaagtgc attagacaag gctcctaacc acttttggat cctttctgtt ttgctgcaac
     3601 catattcctt aaaacaaaca aacaaataaa taaataaaac ccatgccctc ctccgaaagc
     3661 agactaaaag aaggagaata tacaatccaa agtccggaga gctggaaaag aaggtgaaaa
     3721 acctgtactg tgtgcttcaa gcggatcagg agagtctaaa acgatacaca gaccacatgt
     3781 tccgtctgct gtccgaatac gtcatcccga atccttagga gctcctgggc catagtgggt
     3841 tagttcagac ttgaagtgtg ttcttttgat gtggtgtgct tgttctcagc ctcgtcagaa
     3901 tagacgttga tgcttcccaa aacccatccc atctttacaa cattgttcat gccttaagaa
     3961 acgcagagat gtacaataaa ctgtttttta aatgtgtgct cataggtgta tgtgaagggc
     4021 agatcgttag aatcccgg
//
