LOCUS       NM_001015024            3975 bp    mRNA    linear   ROD 01-APR-2024
DEFINITION  Rattus norvegicus oxysterol binding protein-like 5 (Osbpl5), mRNA.
ACCESSION   NM_001015024 XM_001065853 XM_001065970 XM_001066269
VERSION     NM_001015024.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3975)
  AUTHORS   Sandhu,J., Li,S., Fairall,L., Pfisterer,S.G., Gurnett,J.E.,
            Xiao,X., Weston,T.A., Vashi,D., Ferrari,A., Orozco,J.L.,
            Hartman,C.L., Strugatsky,D., Lee,S.D., He,C., Hong,C., Jiang,H.,
            Bentolila,L.A., Gatta,A.T., Levine,T.P., Ferng,A., Lee,R.,
            Ford,D.A., Young,S.G., Ikonen,E., Schwabe,J.W.R. and Tontonoz,P.
  TITLE     Aster Proteins Facilitate Nonvesicular Plasma Membrane to ER
            Cholesterol Transport in Mammalian Cells
  JOURNAL   Cell 175 (2), 514-529 (2018)
   PUBMED   30220461
REFERENCE   2  (bases 1 to 3975)
  AUTHORS   Chung,J., Torta,F., Masai,K., Lucast,L., Czapla,H., Tanner,L.B.,
            Narayanaswamy,P., Wenk,M.R., Nakatsu,F. and De Camilli,P.
  TITLE     INTRACELLULAR TRANSPORT. PI4P/phosphatidylserine countertransport
            at ORP5- and ORP8-mediated ER-plasma membrane contacts
  JOURNAL   Science 349 (6246), 428-432 (2015)
   PUBMED   26206935
REFERENCE   3  (bases 1 to 3975)
  AUTHORS   Maeda,K., Anand,K., Chiapparino,A., Kumar,A., Poletto,M.,
            Kaksonen,M. and Gavin,A.C.
  TITLE     Interactome map uncovers phosphatidylserine transport by
            oxysterol-binding proteins
  JOURNAL   Nature 501 (7466), 257-261 (2013)
   PUBMED   23934110
REFERENCE   4  (bases 1 to 3975)
  AUTHORS   Ghosh,D., Lippert,D., Krokhin,O., Cortens,J.P. and Wilkins,J.A.
  TITLE     Defining the membrane proteome of NK cells
  JOURNAL   J Mass Spectrom 45 (1), 1-25 (2010)
   PUBMED   19946888
REFERENCE   5  (bases 1 to 3975)
  AUTHORS   Suchanek,M., Hynynen,R., Wohlfahrt,G., Lehto,M., Johansson,M.,
            Saarinen,H., Radzikowska,A., Thiele,C. and Olkkonen,V.M.
  TITLE     The mammalian oxysterol-binding protein-related proteins (ORPs)
            bind 25-hydroxycholesterol in an evolutionarily conserved pocket
  JOURNAL   Biochem J 405 (3), 473-480 (2007)
   PUBMED   17428193
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000001.1.
            
            On or before Sep 13, 2008 this sequence version replaced
            XM_001065970.1, XM_001065853.1, XM_001066269.1, NM_001015024.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            RNAseq introns :: partial sample support SAMEA5760393, SAMEA5760476
                              [ECO:0000350]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-292               JAXUCZ010000001.1  208345538-208345829 c
            293-449             JAXUCZ010000001.1  208318150-208318306 c
            450-532             JAXUCZ010000001.1  208315658-208315740 c
            533-613             JAXUCZ010000001.1  208311104-208311184 c
            614-715             JAXUCZ010000001.1  208310874-208310975 c
            716-919             JAXUCZ010000001.1  208310324-208310527 c
            920-1004            JAXUCZ010000001.1  208309508-208309592 c
            1005-1176           JAXUCZ010000001.1  208307108-208307279 c
            1177-1369           JAXUCZ010000001.1  208306648-208306840 c
            1370-1554           JAXUCZ010000001.1  208305302-208305486 c
            1555-1636           JAXUCZ010000001.1  208304841-208304922 c
            1637-1735           JAXUCZ010000001.1  208303468-208303566 c
            1736-1832           JAXUCZ010000001.1  208302990-208303086 c
            1833-1931           JAXUCZ010000001.1  208301638-208301736 c
            1932-2029           JAXUCZ010000001.1  208298204-208298301 c
            2030-2119           JAXUCZ010000001.1  208297728-208297817 c
            2120-2256           JAXUCZ010000001.1  208297497-208297633 c
            2257-2442           JAXUCZ010000001.1  208296897-208297082 c
            2443-2569           JAXUCZ010000001.1  208296475-208296601 c
            2570-2696           JAXUCZ010000001.1  208295566-208295692 c
            2697-2799           JAXUCZ010000001.1  208294446-208294548 c
            2800-3975           JAXUCZ010000001.1  208291441-208292616 c
FEATURES             Location/Qualifiers
     source          1..3975
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q42"
     gene            1..3975
                     /gene="Osbpl5"
                     /note="oxysterol binding protein-like 5"
                     /db_xref="GeneID:361686"
                     /db_xref="RGD:1308402"
     exon            1..292
                     /gene="Osbpl5"
                     /inference="alignment:Splign:2.1.0"
     CDS             242..2938
                     /gene="Osbpl5"
                     /codon_start=1
                     /product="oxysterol-binding protein-related protein 5"
                     /protein_id="NP_001015024.2"
                     /db_xref="GeneID:361686"
                     /db_xref="RGD:1308402"
                     /translation="MALSILSEQFCIRRPRQKPPSTHTMKEEAFLRRRFSLCPPASTP
                     QKTDPRKLPRNLLLGCENELGPITPGRDMESNGPSQPRDEEPLTPGSATKVPLAEYRL
                     CNGSDKECTSPTTRVSKKDTLKAQKENYRQEKKRATKQLFSALTDPSVVIMADSLKIR
                     GTLKSWTKLWCVLKPGVLLIYKTPKVGQWVGTVLLHCCELIERPSKKDGFCFKLFHPL
                     DQSVWAVKGPKGETVGSITQPLPSSYLIFRAASESDGRCWLDALELALRCSSLLRLST
                     CKQGRDGEQGSSPDASPSSLYGLPTSATIPDQDLFPLNGSALENDAFSDKSERENADD
                     SDAETQDHSRKTNESGSDLLDSPGGPRRGTTYVEQVQEELGELDETSQVETVSEENKS
                     LMWVLLRQLRPGMDLSRVVLPTFVLEPRSFLSKLSDYYYHGDLLSRAAAEDDPYCRIK
                     LVLRWYLSGFYKKPKGIKKPYNPILGETFRCCWLHPQTNSHTFYIAEQVSHHPPVSAF
                     YVSNRKDGFCMSGSITAKSKFYGNSLSALLDGKAKLTFLNRKEEYTLTMPYAHCRGLL
                     YGTMTMELGGKVTIQCEKNNLQAELDFKLKPFFGSSTSINQISGKITSGEEVLARLTG
                     HWDRDVFIKEEASGGTKLFWTPSEEVRRQRLKRHTVLLEEQSELESERLWQHVTRAIH
                     EGDQHKATQEKSVLEEAQRQRAREHQQSLTPWKPQLFTLDPLTQEWRYQYEDYSPWDP
                     LKDIAQYEQDGILHTLQRETMSGQTAFLGSPESRHKRPSSDRRLRKASDQPSGHSQVT
                     ESSGSTPESCPDLSDEDFVPGNESPCPRCRREVHRLRMLQEAVLSIQEAQQELHRHLS
                     AMLRSTVRAGQAPAPGLLQNPRSWFLLCIFLTCQLFINYILK"
     exon            293..449
                     /gene="Osbpl5"
                     /inference="alignment:Splign:2.1.0"
     exon            450..532
                     /gene="Osbpl5"
                     /inference="alignment:Splign:2.1.0"
     exon            533..613
                     /gene="Osbpl5"
                     /inference="alignment:Splign:2.1.0"
     exon            614..715
                     /gene="Osbpl5"
                     /inference="alignment:Splign:2.1.0"
     exon            716..919
                     /gene="Osbpl5"
                     /inference="alignment:Splign:2.1.0"
     exon            920..1004
                     /gene="Osbpl5"
                     /inference="alignment:Splign:2.1.0"
     exon            1005..1176
                     /gene="Osbpl5"
                     /inference="alignment:Splign:2.1.0"
     exon            1177..1369
                     /gene="Osbpl5"
                     /inference="alignment:Splign:2.1.0"
     exon            1370..1554
                     /gene="Osbpl5"
                     /inference="alignment:Splign:2.1.0"
     exon            1555..1636
                     /gene="Osbpl5"
                     /inference="alignment:Splign:2.1.0"
     exon            1637..1735
                     /gene="Osbpl5"
                     /inference="alignment:Splign:2.1.0"
     exon            1736..1832
                     /gene="Osbpl5"
                     /inference="alignment:Splign:2.1.0"
     exon            1833..1931
                     /gene="Osbpl5"
                     /inference="alignment:Splign:2.1.0"
     exon            1932..2029
                     /gene="Osbpl5"
                     /inference="alignment:Splign:2.1.0"
     exon            2030..2119
                     /gene="Osbpl5"
                     /inference="alignment:Splign:2.1.0"
     exon            2120..2256
                     /gene="Osbpl5"
                     /inference="alignment:Splign:2.1.0"
     exon            2257..2442
                     /gene="Osbpl5"
                     /inference="alignment:Splign:2.1.0"
     exon            2443..2569
                     /gene="Osbpl5"
                     /inference="alignment:Splign:2.1.0"
     exon            2570..2696
                     /gene="Osbpl5"
                     /inference="alignment:Splign:2.1.0"
     exon            2697..2799
                     /gene="Osbpl5"
                     /inference="alignment:Splign:2.1.0"
     exon            2800..3975
                     /gene="Osbpl5"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 caactttgct gagaccttgc cctaggggat aggggacttg ttttcttctc cgagtccccc
       61 gaggactggc tctagcaact gctggtttac tgggttctag cagccacacc cagctttttg
      121 tctgagcttg gggcagacct atcaggcagg ctggtctccg atctgtgagg cggcctacac
      181 tacacacagt cctgttggaa gggcagagtc actcctcaga tctcaagaag gcagttccac
      241 tatggccctg agcatcttgt ctgagcagtt ctgcatccga aggcctcgcc agaagccccc
      301 cagcacccac accatgaagg aggaggcctt tctccggcgc cgtttctcgc tatgtccgcc
      361 agcttctact ccgcagaaga ctgacccccg gaaactccca cggaacctgc ttctgggctg
      421 tgaaaatgag cttggtccca tcaccccagg aagggacatg gagtccaacg gcccatcaca
      481 acccagagat gaagagcccc tgacaccagg ctccgccacg aaggtgccac tggccgagta
      541 caggctatgc aatggatctg acaaggaatg tacctctcca acgaccaggg tctccaagaa
      601 ggacacgctc aaggcacaga aggagaatta ccggcaggag aagaagcggg ccacaaagca
      661 gcttttcagt gccctgactg accccagcgt ggtcatcatg gctgacagtc tgaagatccg
      721 ggggaccctg aagagctgga cgaagctgtg gtgtgtgctg aagcctgggg tgctgctcat
      781 ctacaagaca cccaaggtgg gccagtgggt gggcacggtg ctgctgcact gttgtgagct
      841 tatcgagcgc ccctccaaga aggatggctt ctgcttcaaa ctcttccacc cgctggacca
      901 gtctgtgtgg gctgtgaagg gccccaaggg cgagactgtg ggctccatca cacagcctct
      961 cccgagcagc tacctgatct tcagggcagc ttctgaatca gacggccgct gctggctaga
     1021 tgccctggag ctggcccttc gctgctccag cctgcttcga ctgagcacat gcaagcaggg
     1081 ccgagatggg gagcaggggt cttcacctga tgcctctccc tcttccctct acggactgcc
     1141 cacctcggcc accatcccag accaagacct gttcccgtta aatgggtcag ccttggagaa
     1201 tgacgcgttc tcagacaagt cagagagaga gaatgctgac gactcagatg ctgagaccca
     1261 ggatcacagc cgcaagacca atgagagtgg gagtgacctg ctggacagcc ctggtgggcc
     1321 acggagggga accacgtatg tagagcaggt ccaggaggag ctgggagagc tggacgagac
     1381 gtcccaggtg gagacagtgt cagaggagaa caagagcctg atgtgggtgc tgctgcgaca
     1441 gctgcggccg ggcatggacc tgtcacgtgt ggtgctgccg accttcgtgt tggagcctcg
     1501 gtccttcctc agcaagctct ctgattacta ctaccatgga gacctgctct ccagggcagc
     1561 agcagaggat gacccctact gccgcatcaa gcttgtgcta cggtggtacc tgtctggctt
     1621 ctacaaaaag cccaagggca tcaagaaacc ctataatccc attctggggg agacttttcg
     1681 ctgctgctgg ctgcaccctc agaccaacag tcacaccttc tacatagcag aacaggtgtc
     1741 tcaccatcct ccagtgtctg ccttctacgt cagcaacagg aaagatggct tctgcatgag
     1801 cggcagcatc acagccaagt cgaagttcta cgggaactct ctgtcagcgc ttctggatgg
     1861 caaggctaag ctcacctttt tgaaccgcaa ggaggagtac accctcacca tgccctatgc
     1921 ccactgccga gggctcctgt acggcaccat gaccatggag ctgggaggta aagtgaccat
     1981 acagtgtgag aagaacaatc tccaagctga actggacttc aaactcaagc ctttctttgg
     2041 gagcagcacc agcatcaacc agatttctgg gaagatcaca tcaggggagg aagtcctggc
     2101 ccgcctcact ggacactggg acagagatgt atttatcaag gaagaggcca gtggaggcac
     2161 caagctcttc tggactccta gtgaggaggt ccgcaggcag cggctgaagc ggcacacggt
     2221 gctgttggaa gagcagagtg aactggagtc tgagaggctc tggcagcatg tcaccagggc
     2281 catccatgag ggtgaccagc acaaagccac ccaggagaag tctgtgctgg aagaggcgca
     2341 gcggcagcgt gcccgtgagc accagcagag cctcactcca tggaagccac agttgttcac
     2401 cctggaccca ctcactcagg aatggcgcta ccaatatgag gactacagcc cttgggaccc
     2461 gctaaaggac attgcccaat atgagcaaga tgggattctt cacactctac agagggagac
     2521 tatgtctgga cagacagcct tcctgggaag tccagagtcc aggcacaaga ggcctagctc
     2581 tgaccggcgg ctccgcaaag ccagtgacca gccctctggc catagccagg tcactgagag
     2641 cagcggctcc acacctgagt cctgcccaga cctctctgat gaggactttg ttcctggtaa
     2701 tgagagcccg tgtcctcggt gcaggcgaga ggtacaccgg ctaaggatgc tacaagaggc
     2761 agtgctgtcc attcaggaag ctcagcaaga gctgcatcgg cacctttcag ccatgttgag
     2821 atccacagtg cgtgctgggc aggcgccggc ccccggcctc ctgcagaatc cccgctcctg
     2881 gttcctgctt tgcatcttcc tgacatgtca gctattcatt aactatatcc tcaaataaga
     2941 gcccttggaa tcagcaaggt gatgcctgaa gaactccctc ctaggcaccc agcactttac
     3001 accggcctgc agagacagtg gggcccacag gcagggccac tgggacagaa gggtcctcat
     3061 acaagaggat gacaggtggg gcctggggct atgagggtgc tgtgactcct gctgtaggac
     3121 cctccaggaa gcactggcct ctcctacaga gtcctccacc tagcaccggc cttaatgcta
     3181 aagccaaatg tggtttctgc cctgcagcgt gcccctggta atctcgagtt gccactccca
     3241 agccagcccc cactggccat atggcatcat atctgggggt caggagggcc tgtgcaggct
     3301 ttggacagcc acttgccaca gcagaggaga gagtgaggtt tccaggagca gcaggaagga
     3361 agaccccaga attccccagg gctctttgag tggtaatgtt gacttctgga gagtctgccc
     3421 accttgtgct cacacaagca tggacaggac actgggactt ttatcctgtt gttaagctgt
     3481 ttccacagaa gcccgttcag gtagttactt cacccacatt ggccctatag ccagaggagt
     3541 gccctggcta actgcagtgt gagcttgtaa gcaacagaag tgcccaggag ctgaccccaa
     3601 aggccaggaa ggctcgagct tgccactttc cctgaccaat acagtcttcc catcctgttg
     3661 acattctgac tacatataaa ttgcaatatt tgaggcagct ctgtgcagtg agcagcctct
     3721 gcatccagac cctgacccta tgtggatgat gctctgtgta tacgtgtgtg tgtgtgtgtg
     3781 tgtgtgtgtg tgtgtgtgtg tgtgtgtgta tgtgggcacc tatgcatact cacattcaga
     3841 gccttaatac ctagttggtg ccatctccac tgtatctgat ccttcatttc tgagttttgt
     3901 atccatttgt ctctctcctt cctcagcctg ggggtatgtc tgctccatgc cttgaaataa
     3961 atggaaatac atgta
//
