LOCUS       NM_001105940            1058 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus ORMDL sphingolipid biosynthesis regulator 2
            (Ormdl2), mRNA.
ACCESSION   NM_001105940 XM_001071533 XM_213832
VERSION     NM_001105940.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1058)
  AUTHORS   Siow,D., Sunkara,M., Dunn,T.M., Morris,A.J. and Wattenberg,B.
  TITLE     ORMDL/serine palmitoyltransferase stoichiometry determines effects
            of ORMDL3 expression on sphingolipid biosynthesis
  JOURNAL   J Lipid Res 56 (4), 898-908 (2015)
   PUBMED   25691431
REFERENCE   2  (bases 1 to 1058)
  AUTHORS   Breslow,D.K., Collins,S.R., Bodenmiller,B., Aebersold,R.,
            Simons,K., Shevchenko,A., Ejsing,C.S. and Weissman,J.S.
  TITLE     Orm family proteins mediate sphingolipid homeostasis
  JOURNAL   Nature 463 (7284), 1048-1053 (2010)
   PUBMED   20182505
REFERENCE   3  (bases 1 to 1058)
  AUTHORS   Hjelmqvist,L., Tuson,M., Marfany,G., Herrero,E., Balcells,S. and
            Gonzalez-Duarte,R.
  TITLE     ORMDL proteins are a conserved new family of endoplasmic reticulum
            membrane proteins
  JOURNAL   Genome Biol 3 (6), RESEARCH0027 (2002)
   PUBMED   12093374
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH474104.2.
            
            On or before Oct 3, 2007 this sequence version replaced
            XM_213832.4, XM_001071533.1.
            
            ##Evidence-Data-START##
            CDS exon combination :: CF977104.1, FM134902.1 [ECO:0000331]
            RNAseq introns       :: single sample supports all introns
                                    SAMEA5760400, SAMEA5760476 [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..1058
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="7"
                     /map="7q11"
     gene            1..1058
                     /gene="Ormdl2"
                     /note="ORMDL sphingolipid biosynthesis regulator 2"
                     /db_xref="GeneID:288783"
                     /db_xref="RGD:1305642"
     exon            1..81
                     /gene="Ormdl2"
                     /inference="alignment:Splign:2.1.0"
     exon            82..381
                     /gene="Ormdl2"
                     /inference="alignment:Splign:2.1.0"
     CDS             208..669
                     /gene="Ormdl2"
                     /note="ORM1-like 2"
                     /codon_start=1
                     /product="ORM1-like protein 2"
                     /protein_id="NP_001099410.1"
                     /db_xref="GeneID:288783"
                     /db_xref="RGD:1305642"
                     /translation="MNVGVAHSEVNPNTRVMNSRGIWLAYVILVGLLHVVLLSIPFFS
                     IPVVWTLTNVIHNLAMYVFLHTVKGTPFETPDQGKARLLTHWEQMDYGLQFTSSRKFL
                     SISPIVLYLLASFYTKYDAAHFLINTASLLSVLLPKLPQFHGVRLFGINKY"
     exon            382..533
                     /gene="Ormdl2"
                     /inference="alignment:Splign:2.1.0"
     exon            534..1058
                     /gene="Ormdl2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cagggcgaaa gtcgggcact tcctggagac cacaggtgta agagctgtgc cccaagccgg
       61 acgggctcct gaagctggca gggaaatcct ttcattccca agacttcagg ggattttggc
      121 ttttcaggag acaactgggg aacaagctca atcaggggta atgaggaaac tgagttggac
      181 tcctgcctga tccctcactg tggtaggatg aatgtggggg tggcccacag cgaagtaaac
      241 cccaacactc gagtgatgaa cagtcggggc atctggctgg cctacgtcat cttggtagga
      301 ctgctgcatg tggtgctcct cagcatccct ttcttcagca ttcctgttgt ctggaccctg
      361 accaacgtca tccataactt ggcaatgtat gtcttcctac atacagtcaa agggacgccc
      421 tttgagaccc ctgaccaagg aaaggctcgg cttttgacac actgggagca gatggactac
      481 ggactacagt ttacctcctc acgaaagttc ctcagcattt cccctattgt actctaccta
      541 ctggccagct tctacaccaa gtatgatgct gctcatttcc tcatcaacac tgcctcactg
      601 ctcagcgtac tgctgcctaa gctgccccag ttccatgggg ttcgcctctt tggaatcaac
      661 aaatactgaa agacgggctg ataggtctgc aggcattgag ggaaggcact ggaactaata
      721 gaatgttttt cccttctccg tactatcttc tgtatcttgg aagcctgaca gataagataa
      781 acctttctaa actccaagaa gggagaaatt ggaaaatggg gttcctgggc ccagccttaa
      841 aagggtcaag gttctctgaa tcaggaaagg tgagtgaggt tagggcctgc cactcactct
      901 cctctatcta gcaagaagcc atcaatgctt gggcagcttt tctggtaatt atgttttgcc
      961 atatcctcta aacccgctaa cttcaagttc tgttttgctg taaatttttc ttaaaataaa
     1021 gtctttcagt tatggctgaa atttgataag caaggaca
//
