LOCUS       NM_001014186            2115 bp    mRNA    linear   ROD 23-MAR-2023
DEFINITION  Rattus norvegicus origin recognition complex, subunit 5 (Orc5),
            mRNA.
ACCESSION   NM_001014186 XM_342617
VERSION     NM_001014186.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2115)
  AUTHORS   Coulombe P, Nassar J, Peiffer I, Stanojcic S, Sterkers Y, Delamarre
            A, Bocquet S and Mechali M.
  TITLE     The ORC ubiquitin ligase OBI1 promotes DNA replication origin
            firing
  JOURNAL   Nat Commun 10 (1), 2426 (2019)
   PUBMED   31160578
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2115)
  AUTHORS   Shen Z, Sathyan KM, Geng Y, Zheng R, Chakraborty A, Freeman B, Wang
            F, Prasanth KV and Prasanth SG.
  TITLE     A WD-repeat protein stabilizes ORC binding to chromatin
  JOURNAL   Mol Cell 40 (1), 99-111 (2010)
   PUBMED   20932478
REFERENCE   3  (bases 1 to 2115)
  AUTHORS   Dejardin J and Kingston RE.
  TITLE     Purification of proteins associated with specific genomic Loci
  JOURNAL   Cell 136 (1), 175-186 (2009)
   PUBMED   19135898
REFERENCE   4  (bases 1 to 2115)
  AUTHORS   Siddiqui K and Stillman B.
  TITLE     ATP-dependent assembly of the human origin recognition complex
  JOURNAL   J Biol Chem 282 (44), 32370-32383 (2007)
   PUBMED   17716973
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC088447.1.
            
            On Apr 20, 2005 this sequence version replaced XM_342617.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC088447.1, SRR8487227.72664.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2115
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="4"
                     /map="4q11"
     gene            1..2115
                     /gene="Orc5"
                     /gene_synonym="Orc5l"
                     /note="origin recognition complex, subunit 5"
                     /db_xref="GeneID:362304"
                     /db_xref="RGD:1561088"
     exon            1..149
                     /gene="Orc5"
                     /gene_synonym="Orc5l"
                     /inference="alignment:Splign:2.1.0"
     CDS             78..1385
                     /gene="Orc5"
                     /gene_synonym="Orc5l"
                     /codon_start=1
                     /product="origin recognition complex subunit 5"
                     /protein_id="NP_001014208.1"
                     /db_xref="GeneID:362304"
                     /db_xref="RGD:1561088"
                     /translation="MSHLESMVLCREAQVSTLQSLFGEREHFSFPSIFIYGHTASGKT
                     YVTQTLLKTLELPHAFVNCVECFTSRLLLEQILNKLSHLSSSEAECSTETTCETFNDF
                     VRLFKQVTSAEHLKDQTVYIVLDKADYLRDMEANLLPGFLRLQELTDRNVTVIFLSEI
                     IWEKFRPNTGCFEPFVLHFPDYSIGNLQKILSHDHPPGYSADFYSAYINILLGVFYTV
                     CRDLKELRHLAVLNFPKYCEPVVKGEAGERDTRKLWRNIEPHLKKAMQTVYLREVSSS
                     QWETLQKDATDLGQLKGLSAYTHVELPYYSKFILIAAYLASYNPARTDRRFFLKHHGK
                     IKKTNFLKKHEKTSNHLLGPKPFPLDRLLAILYSIVDSRVAPTANIFSQITSLVTLQL
                     LTVVGHEDQLNGPKYKCTVSLDFIRSIARTVNFDIIKYLYDFL"
     exon            150..242
                     /gene="Orc5"
                     /gene_synonym="Orc5l"
                     /inference="alignment:Splign:2.1.0"
     exon            243..443
                     /gene="Orc5"
                     /gene_synonym="Orc5l"
                     /inference="alignment:Splign:2.1.0"
     exon            444..518
                     /gene="Orc5"
                     /gene_synonym="Orc5l"
                     /inference="alignment:Splign:2.1.0"
     exon            519..630
                     /gene="Orc5"
                     /gene_synonym="Orc5l"
                     /inference="alignment:Splign:2.1.0"
     exon            631..761
                     /gene="Orc5"
                     /gene_synonym="Orc5l"
                     /inference="alignment:Splign:2.1.0"
     exon            762..810
                     /gene="Orc5"
                     /gene_synonym="Orc5l"
                     /inference="alignment:Splign:2.1.0"
     exon            811..901
                     /gene="Orc5"
                     /gene_synonym="Orc5l"
                     /inference="alignment:Splign:2.1.0"
     exon            902..954
                     /gene="Orc5"
                     /gene_synonym="Orc5l"
                     /inference="alignment:Splign:2.1.0"
     exon            955..1067
                     /gene="Orc5"
                     /gene_synonym="Orc5l"
                     /inference="alignment:Splign:2.1.0"
     exon            1068..1115
                     /gene="Orc5"
                     /gene_synonym="Orc5l"
                     /inference="alignment:Splign:2.1.0"
     exon            1116..1226
                     /gene="Orc5"
                     /gene_synonym="Orc5l"
                     /inference="alignment:Splign:2.1.0"
     exon            1227..1339
                     /gene="Orc5"
                     /gene_synonym="Orc5l"
                     /inference="alignment:Splign:2.1.0"
     exon            1340..2087
                     /gene="Orc5"
                     /gene_synonym="Orc5l"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cgagaactac gctgaatgag cggcgccggt ctgaccggcg gccaactact ctgcagtatc
       61 aggtggtgcc cgccaaaatg tctcacttgg agagcatggt gctctgtcga gaggcccaag
      121 tgtccacttt gcagtccctg tttggagaga gagagcactt cagctttccg tccatcttca
      181 tttatggaca cactgccagt gggaagacct atgtgacaca gacattgttg aaaactttag
      241 agctcccaca tgcctttgtg aattgtgttg aatgttttac ttcaaggcta cttttggaac
      301 aaattttaaa caagctgagt catcttagtt cttcagaggc agagtgttct acagaaacga
      361 cttgtgaaac atttaatgac tttgtccggt tgtttaagca agtgaccagt gctgaacatc
      421 tcaaggatca gactgtgtat attgttctgg ataaagctga ctatctgaga gacatggaag
      481 caaatctctt gcctgggttt cttaggctgc aagagttgac tgacagaaac gtgactgtta
      541 tcttcctcag tgagattatt tgggaaaaat ttcgtccaaa cactggatgc ttcgagccat
      601 ttgtcttaca cttccctgac tacagcatag ggaaccttca aaagatcctg tcccacgatc
      661 atcctccagg gtattcagct gacttttact ctgcctacat taatattctc cttggagttt
      721 tctacactgt ctgtcgagat ctgaaagagc tcagacacct ggcagtgctt aatttcccca
      781 aatattgtga gcctgtagtt aaaggagaag caggtgagcg tgatactcgc aaactgtgga
      841 gaaatattga acctcacttg aagaaggcca tgcagacggt gtatctgagg gaggtctcaa
      901 gttcgcagtg ggaaacatta cagaaagatg ccacagacct gggacagctg aaagggctct
      961 cggcgtacac ccatgtggag cttccatatt actccaagtt tattcttatt gctgcgtacc
     1021 ttgcctctta caaccccgcg agaacggaca ggaggttctt cctaaagcat catggaaaaa
     1081 tcaagaaaac taactttcta aagaaacatg agaagacaag caatcatctt cttggaccaa
     1141 agccatttcc attggacaga ttattagcaa tattatatag tatagtggac agcagagtgg
     1201 ctccaactgc aaacatcttc tcccagatta cctccctagt gactcttcag ctgttaaccg
     1261 tagttggtca tgaagatcaa cttaatggac caaaatacaa atgcacagtt tctctagatt
     1321 tcatcagatc tattgcgcgg acggtgaact ttgacataat aaaatacttg tatgatttct
     1381 tgtgaaaaca agcttcaaag ccatatggac actgtgacaa tgactaagcc aagctgtgtt
     1441 catccaacta ctcggctggc cagggaaagg agttctttgg ctctattgga tttgtccaaa
     1501 caggtgctgg cccagcatgg agcctgatga aaaccctctg attggtctgg gtagatgtga
     1561 gcagaagact atttaccagg ggcccgggag tatttggaag caacgtgtta attataaaca
     1621 gcagggtttg agcacaatct gttctactct taatgatgtt atcttaacac tgaaattgcc
     1681 tgaaacccat ttacttagga ctgtgctttg ctctatgaac tatcccctgc actttgaaca
     1741 tgccagcagc ccttgtttgt ttgcccagcc ttttcacttc ctctccacgg gagccgctgc
     1801 cagctcttgc cagagcagat ttcctaaggc cactgtttta gaagatcatg gttgctaaag
     1861 tatgcgctgt atatgcttat ggtttaccct ggttttccca aacacaaggc agcttgttca
     1921 ttgtacacac aacagcttca tgtctgactc tgcttgctgc cctgacagta ctggtcactc
     1981 tcgttaacca ccaatggctt tttagagaat gttgttttcc ttcctttttg cttttgagtc
     2041 gctgaggttt gagagcccca caataaaatt cttcctttta cattgtaaaa aaaaaaaaaa
     2101 aaaaaaaaaa aaaaa
//
