LOCUS       XM_039104469            5315 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus origin recognition complex, subunit 4
            (Orc4), transcript variant X9, mRNA.
ACCESSION   XM_039104469
VERSION     XM_039104469.1
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051338.1) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Feb 22, 2024 this sequence was replaced by
            XM_039104469.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5315
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="3"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..5315
                     /gene="Orc4"
                     /note="origin recognition complex, subunit 4; Derived by
                     automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 40 ESTs, 4 long SRA reads, 1 Protein, and 100%
                     coverage of the annotated genomic feature by RNAseq
                     alignments, including 19 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:295596"
                     /db_xref="RGD:735212"
     CDS             238..1584
                     /gene="Orc4"
                     /codon_start=1
                     /product="origin recognition complex subunit 4 isoform X3"
                     /protein_id="XP_038960397.1"
                     /db_xref="GeneID:295596"
                     /db_xref="RGD:735212"
                     /translation="MSNRKSKNNIHAECLSQVQRILRERFCHHTPHSNLFGVQVQYKH
                     LIELLKRTAIYGESNSLLIVGPRGSGKTTLLNHALKELMQIGDMSENVLQVHLNGLLQ
                     TNDKIALKEITRQLNLENVVGDKVFGSFAENLSFLLEALQKGNRTSSCPVIFILDEFD
                     LFAHQKNQTLLYNLFDISQSAQTPIAVIGLTCRLLILRRSELLKVYFHDILELLEKRV
                     KSRFSHRQIHLMNSFDFPQYLKIFKEQLSLPAEFPDKIFAEKWNENAHCLSEDSTVLE
                     VLQKHFNVNKNLQSLHMLLMLALNRVTVTHPFMTSADLMEAQHLCSLDAKASIVHGLS
                     VLEICLIIAMKHLNDIYEEEPFNFQMVYNEFQKFIQRKAHSVYNFEKPVVMKAFEHLQ
                     QLELIKPMERTSVNSQREYQLVKLLLDNTQIMNALQKYSNCPTDVRQWATSSLSWL"
ORIGIN      
        1 ggaggcaaag gaggaggagg agagctgggg aagtggctgc tcccggtgta gggagatgtc
       61 tccagccagg gccaagcagc agcagcagca gcagcaacag cagcagtagc agcagcagca
      121 gcagcagcaa agggtgaaac agagctggga aggcggtgaa caatcctggg tccttacagt
      181 cggcggaggc tgcccgattt aggcaggctt tattgagaga gatttgagtt agtcaagatg
      241 agcaatcgta aaagcaagaa taacatacat gcagagtgtc tttcccaggt acaaagaatt
      301 ttacgtgaaa ggttttgtca tcatactcct catagcaacc tatttggagt gcaagtacaa
      361 tacaagcatt taattgagct actcaaaaga actgctatct atggagaaag taattcttta
      421 ctcattgttg gaccacgagg atcaggaaag accacgttat taaatcatgc cttgaaagag
      481 ctcatgcaaa taggagacat gagtgaaaat gtgttacaag ttcacttaaa tggactgcta
      541 cagacaaatg ataaaattgc tctgaaagag atcacaagac aattaaatct agaaaatgta
      601 gttggagata aagtttttgg aagctttgct gaaaaccttt cgtttcttct ggaagctttg
      661 cagaaaggta accggactag cagttgccca gtgatcttca tactggatga atttgatctt
      721 tttgctcatc agaaaaacca aacactcctt tataatcttt ttgacatttc tcaatctgca
      781 cagacaccaa tagcagttat tggccttaca tgtagactgt taattttaag aagatcagaa
      841 cttctcaaag tttattttca tgatattttg gaactcttag aaaagagagt gaagtcacga
      901 ttttctcacc ggcagataca tttaatgaat tcatttgatt ttccgcaata tttgaaaata
      961 tttaaagaac aattatctct acctgcagaa ttcccagata agatttttgc tgagaaatgg
     1021 aatgagaatg ctcattgtct ctccgaagat tcaactgtgc ttgaagttct acagaagcat
     1081 ttcaatgtca acaaaaactt gcaatcatta catatgctat tgatgcttgc tttaaatcga
     1141 gtaaccgtga cacacccatt tatgacctca gcagatctga tggaggcgca gcacttgtgt
     1201 agcttggatg ccaaagcgag tattgtacat ggtctgtcag tcttggaaat ctgtcttata
     1261 atagcaatga aacatttaaa tgacatatat gaagaggagc cctttaattt tcaaatggtg
     1321 tataatgaat ttcagaaatt cattcaaaga aaggcccatt ctgtttataa ctttgagaaa
     1381 cctgtggtca tgaaggcatt tgagcactta caacaattgg aattaataaa acccatggaa
     1441 agaacctcag tcaattctca gagagaatac cagctagtca aactactttt ggataatact
     1501 cagattatga atgccctaca gaaatactcc aactgcccta cagatgtcag gcagtgggca
     1561 acatcctcgc tcagctggct gtgaagattt taagtacatt tctgtgaaga cctaaaacta
     1621 gtgttcttta ataagatacg ctactacatt actttgttta taaatattgt ttatgggaaa
     1681 cctgcactta gtatcttgac tatgttttga atattgactg tgcatggaca gtttcattaa
     1741 tttaaattac accatacaag taacaattca aaataataaa atgtgcttat tttacgggtg
     1801 atccataaga tgacttgata ctcttgtgaa atgtatgtgg tccattggaa aggttcattt
     1861 caactcagca tttacagatc ttaatgctaa gcagtgagga gagaaatagg aacaggaatg
     1921 acatgaggaa tattccggct agattaggag cctgtggaga gtggggttgg tttggttttc
     1981 tgagttggtt tctataggat cctgccattt tggatcctgt acagatcccc atggctgaag
     2041 agctcgtgtg gaaagagtcc aaacaattca gcattttctt ctgtgcacat ttcaccacaa
     2101 ctggaggagt ttttgtttaa tatacattct gggtatactt tagttcaaaa gggatcaaaa
     2161 ttgccatcta acaggtatct taaaggattc ctggtaacta cttccacaaa taagtattca
     2221 ttccacagtg tgagctgttg gctttgaatt ctctgagaac aaggaatgtt ggtcagagtt
     2281 cacttcctaa atacatagac atagaactaa caggttgaaa tagaatataa tctcagtgag
     2341 ttactttgtt gaagaatatt tgattgaata tttagttaca gtaagatttt ataaaataga
     2401 gatcccttct acttgcaact tgtaaagttt ctgcagaatt aaatgctatt ttatttatag
     2461 attaggaaac tctcaccagt gtctgagtcc aggatcacag tatgggaatg acaggtgtga
     2521 ccttgaatgc agcttcggtt gactgacatt aaagccaatg ttgttaaaaa ctaaagctta
     2581 gcaacaacgt tttactattt ttataggata ctgtaagaaa taatttgact tttaagaaat
     2641 cttaaatata aatttcctct gcattaatgt agtacctcat agttaaaacc tactttcttc
     2701 atacacagcc ttttcctttc ttacaataaa acatgtttag ctttctatgc tttttttaat
     2761 catgataaaa atgaagccat agtaactatc aaggtcatag aagtatagac gtagatgccc
     2821 aatttttaaa ctactttcac cttataagtt gttcaaactt cattattaga gaattctaaa
     2881 atgagaaaaa ttagattctt aaaaaaccta agaatgttca aggtggaagt gtccgtctat
     2941 aacatacaat ttcacaactt aagagtagaa gcaagaaagg taaatacttt taggaggttc
     3001 caaactagtc ttgagttatc ccaacaagag cggaggggga ggaatgattg tgaacagaaa
     3061 gtctgactgg actttctctg cagtgaagag aatttagagt ctctgctcaa gacgccccct
     3121 ggccaagaga cgttaaaaca gacagaaaag actttgcatg tttcccttct accgtgtggc
     3181 ctactgaaac ttgggtcttg tttaaaaggc atctgatttt atgcagacac atgtcggaaa
     3241 agttagactc tcttgttcag acttccatat ggtaatgtct tgtaatgtaa ggacatagta
     3301 tccactgacc cagagagtta gacatcgcag actgcacaat gggaaaccgc gtttctgtac
     3361 cagtgaaaca gtctgatcag actacagtgg gaggaaaatt ccctaattca caaacttccc
     3421 tgattttttt taccctctgt aagaacataa atacacagct aaagaaaaac tgcatgtgca
     3481 aataatacca tattcatttt ttatttaaca tggggatgga atggggatag catacatttt
     3541 atttgtacaa tatttaacaa tcacttattc aaggtgggat tttatgggga tttttttcat
     3601 ttttagcttt ctgttaaata cttgcagaaa aaaaaatagc aagtacaata tgacagtagt
     3661 acaacaacct gtgcccaaaa cactgacaag aaatacagag taaagctaaa ataattgttt
     3721 cccaatattt tgagaggtaa caaataggga gatacgggtt gagactgcat aaaaaacgta
     3781 ctgctggttg aatatctgag gtaaatgatg tttaatcaag atgctacttg tatctttgtc
     3841 cataaattgt aaataatttt atgcacatta taccaaatct tcctaaaaag taatttttca
     3901 aaaaagtaaa aaagagaaac tggaaaatat ctgatgaagc atttttttaa aaaacagtaa
     3961 tcagtctatt ccactaaact accatctatc tggtgagggt atttttccca accatttgaa
     4021 ttttacttaa atgtgactta attattaagg ataagaaaaa gggccagaag cgatgttttc
     4081 ataattttgt gatacatgat tctgttttta agtccaaacg tatttgtttt tgtttttcct
     4141 ggttgtattt ttagaatatc accatgaaag atagtgcaag ttcatgggac caataattgt
     4201 gaggcacagt ctctgttctg gaattcacaa ggtacctgta ataaaacatc caaacaagag
     4261 tcacaaatca catgctaaaa ctcctagcat ctaaaacaca tacaagatct gtgcagggca
     4321 tagatagact tcaaataaat tcaaacactg gttactccgt cagtcctgtg gcagttgatc
     4381 ataaagcatt ctcacacggg agatctgggc aaggtagagt aagagcagca gttctggtgg
     4441 gtgtcagaaa ggcaaagtac aagacatcat gagcaccata cacatgaagg tatacagggg
     4501 tccaagtttg ccatctccct agaaatgaat cgttttcact ctttgatctt tctttttcat
     4561 tgtccctaac tcaaactttc tatctgccca ctctgcactt actgtaaacc aaacacgaaa
     4621 atgccctgca aaagaaagtc acaagactag gcataaggac aggtagtcac tggaacattc
     4681 ttaacgttac tgcttataaa aaaggctttc ttgttaatgt agttcttaag agaatacaag
     4741 ttttaaaatt gataagctag atttacatac aatacccaag atttctaaaa cataaattcc
     4801 ctagcgtgaa gacaaagcat tttatatcat gaaccagtct tggtaaaatt tatctgtagt
     4861 gctttcctaa gccgaacagt cataatatcc ctcatgtatc agctcttaaa gggagttgaa
     4921 tgtttacaac cagtagcagt ttgcttatgg atgaaaagtt tccttgtatg catattttct
     4981 tatggttttc cttgattaca agtggaagca aacctgaatc aaaaatttga ggggccaaat
     5041 atgtaggaat atgtcaaaaa cagtgaacac tgaacttggc aatcttagga atacagtgac
     5101 accttgggta catagacaac gtacaattct ctatggtatg tggcatacag acaagaatgc
     5161 tattatcctc cccacttaaa gtctgttgac ctatgtattg tttatgatta ttcttcccag
     5221 agattagtgc acattatatg taaaaggtag tgtctgatgt cttaaccatc tgaagataat
     5281 gcattcacag tgagctcctg atagtaacat aacaa
//
