LOCUS       NP_001000088             322 aa            linear   ROD 26-OCT-2024
DEFINITION  olfactory receptor Olr1605 [Rattus norvegicus].
ACCESSION   NP_001000088 XP_223816
VERSION     NP_001000088.1
DBSOURCE    REFSEQ: accession NM_001000088.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (residues 1 to 322)
  AUTHORS   Gaudet,P., Livstone,M.S., Lewis,S.E. and Thomas,P.D.
  TITLE     Phylogenetic-based propagation of functional annotations within the
            Gene Ontology consortium
  JOURNAL   Brief Bioinform 12 (5), 449-462 (2011)
   PUBMED   21873635
COMMENT     REVIEWED REFSEQ: This record has been curated by Janet Young and
            Barbara Trask (FHCRC). The reference sequence was derived from
            JAXUCZ010000015.1.
            
            On Aug 30, 2004 this sequence version replaced XP_223816.1.
            
            Summary: Olfactory receptors interact with odorant molecules in the
            nose, to initiate a neuronal response that triggers the perception
            of a smell. The olfactory receptor proteins are members of a large
            family of G-protein-coupled receptors (GPCR) arising from single
            coding-exon genes. Olfactory receptors share a 7-transmembrane
            domain structure with many neurotransmitter and hormone receptors
            and are responsible for the recognition and G protein-mediated
            transduction of odorant signals. The olfactory receptor gene family
            is the largest in the genome. [provided by RefSeq, Jul 2008].
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..322
                     /organism="Rattus norvegicus"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="15"
                     /map="15p16"
     Protein         1..322
                     /product="olfactory receptor Olr1605"
                     /note="olfactory receptor gene Olr1605; olfactory receptor
                     1605"
                     /calculated_mol_wt=36341
     Region          24..300
                     /region_name="7tmA_OR2T-like"
                     /note="olfactory receptor subfamily 2T and related
                     proteins, member of the class A family of
                     seven-transmembrane G protein-coupled receptors; cd15421"
                     /db_xref="CDD:320543"
     Region          25..51
                     /region_name="TM helix 1"
                     /note="TM helix 1 [structural motif]"
                     /db_xref="CDD:320543"
     Region          58..84
                     /region_name="TM helix 2"
                     /note="TM helix 2 [structural motif]"
                     /db_xref="CDD:320543"
     Site            order(80,83..84,96..101,103..104,107,152,154..158,194,
                     197..199,201..203,205..206,251,254..255,257..258,261,
                     267..268,270..272,275,278..279)
                     /site_type="other"
                     /note="putative ligand binding pocket [chemical binding]"
                     /db_xref="CDD:320543"
     Region          96..126
                     /region_name="TM helix 3"
                     /note="TM helix 3 [structural motif]"
                     /db_xref="CDD:320543"
     Region          139..160
                     /region_name="TM helix 4"
                     /note="TM helix 4 [structural motif]"
                     /db_xref="CDD:320543"
     Region          194..224
                     /region_name="TM helix 5"
                     /note="TM helix 5 [structural motif]"
                     /db_xref="CDD:320543"
     Region          231..261
                     /region_name="TM helix 6"
                     /note="TM helix 6 [structural motif]"
                     /db_xref="CDD:320543"
     Region          268..293
                     /region_name="TM helix 7"
                     /note="TM helix 7 [structural motif]"
                     /db_xref="CDD:320543"
     CDS             1..322
                     /gene="Or2t35"
                     /gene_synonym="Olr1605; ratchr15-12385736-12384768_ORF"
                     /coded_by="NM_001000088.1:1..969"
                     /db_xref="GeneID:289923"
                     /db_xref="RGD:1333947"
ORIGIN      
        1 meavyknstd fillglithp tfpglifavv fsifvvavta nlvmimlirm dsrlhtpmyf
       61 llsqlsimdt vyicitvpkm lqdllskdkt isflgcalqi flyltligge ffllglmayd
      121 rfvavcnplr ypiimnpric llmvlgswag gsldgfmltp vtmsfpycgs reinhffcei
      181 pavlklsctd tslyetlmya ccvlmllipi sfisvsytri litvyhmssa egrrkafttc
      241 sshiivvsif ygaafytnvl phsyhtpekd kvvsafytil tpmlnpliys lrnrdvaaal
      301 rkvlrkhass qrfrvrhvpe ky
//
