LOCUS       NM_053548               1217 bp    mRNA    linear   ROD 30-MAR-2024
DEFINITION  Rattus norvegicus opsin 1, medium wave sensitive (Opn1mw), mRNA.
ACCESSION   NM_053548
VERSION     NM_053548.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1217)
  AUTHORS   Hofmann,L., Alexander,N.S., Sun,W., Zhang,J., Orban,T. and
            Palczewski,K.
  TITLE     Hydrogen/Deuterium Exchange Mass Spectrometry of Human Green Opsin
            Reveals a Conserved Pro-Pro Motif in Extracellular Loop 2 of
            Monostable Visual G Protein-Coupled Receptors
  JOURNAL   Biochemistry 56 (17), 2338-2348 (2017)
   PUBMED   28402104
REFERENCE   2  (bases 1 to 1217)
  AUTHORS   Ahmedli,N.B., Gribanova,Y., Njoku,C.C., Naidu,A., Young,A.,
            Mendoza,E., Yamashita,C.K., Ozgul,R.K., Johnson,J.E., Fox,D.A. and
            Farber,D.B.
  TITLE     Dynamics of the rhomboid-like protein RHBDD2 expression in mouse
            retina and involvement of its human ortholog in retinitis
            pigmentosa
  JOURNAL   J Biol Chem 288 (14), 9742-9754 (2013)
   PUBMED   23386608
REFERENCE   3  (bases 1 to 1217)
  AUTHORS   Sun,X., Haley,J., Bulgakov,O.V., Cai,X., McGinnis,J. and Li,T.
  TITLE     Tubby is required for trafficking G protein-coupled receptors to
            neuronal cilia
  JOURNAL   Cilia 1 (1), 21 (2012)
   PUBMED   23351594
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 1217)
  AUTHORS   Zhang,X., Bedigian,A.V., Wang,W. and Eggert,U.S.
  TITLE     G protein-coupled receptors participate in cytokinesis
  JOURNAL   Cytoskeleton (Hoboken) 69 (10), 810-818 (2012)
   PUBMED   22888021
REFERENCE   5  (bases 1 to 1217)
  AUTHORS   Sun,H.
  TITLE     Membrane receptors and transporters involved in the function and
            transport of vitamin A and its derivatives
  JOURNAL   Biochim Biophys Acta 1821 (1), 99-112 (2012)
   PUBMED   21704730
  REMARK    Review article
REFERENCE   6  (bases 1 to 1217)
  AUTHORS   Zhao,Y., Hong,D.H., Pawlyk,B., Yue,G., Adamian,M., Grynberg,M.,
            Godzik,A. and Li,T.
  TITLE     The retinitis pigmentosa GTPase regulator (RPGR)- interacting
            protein: subserving RPGR function and participating in disk
            morphogenesis
  JOURNAL   Proc Natl Acad Sci U S A 100 (7), 3965-3970 (2003)
   PUBMED   12651948
REFERENCE   7  (bases 1 to 1217)
  AUTHORS   Hong,D.H., Pawlyk,B.S., Shang,J., Sandberg,M.A., Berson,E.L. and
            Li,T.
  TITLE     A retinitis pigmentosa GTPase regulator (RPGR)-deficient mouse
            model for X-linked retinitis pigmentosa (RP3)
  JOURNAL   Proc Natl Acad Sci U S A 97 (7), 3649-3654 (2000)
   PUBMED   10725384
REFERENCE   8  (bases 1 to 1217)
  AUTHORS   Radlwimmer,F.B. and Yokoyama,S.
  TITLE     Genetic analyses of the green visual pigments of rabbit
            (Oryctolagus cuniculus) and rat (Rattus norvegicus)
  JOURNAL   Gene 218 (1-2), 103-109 (1998)
   PUBMED   9751808
REFERENCE   9  (bases 1 to 1217)
  AUTHORS   Yokoyama,S. and Radlwimmer,F.B.
  TITLE     The 'five-sites' rule and the evolution of red and green color
            vision in mammals
  JOURNAL   Mol Biol Evol 15 (5), 560-567 (1998)
   PUBMED   9580985
REFERENCE   10 (bases 1 to 1217)
  AUTHORS   Asenjo,A.B., Rim,J. and Oprian,D.D.
  TITLE     Molecular determinants of human red/green color discrimination
  JOURNAL   Neuron 12 (5), 1131-1138 (1994)
   PUBMED   8185948
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000021.1.
            
            On Sep 1, 2022 this sequence version replaced NM_053548.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-137               JAXUCZ010000021.1  157056355-157056491
            138-434             JAXUCZ010000021.1  157061673-157061969
            435-603             JAXUCZ010000021.1  157064813-157064981
            604-769             JAXUCZ010000021.1  157066178-157066343
            770-1009            JAXUCZ010000021.1  157069595-157069834
            1010-1217           JAXUCZ010000021.1  157076509-157076716
FEATURES             Location/Qualifiers
     source          1..1217
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="X"
                     /map="Xq37"
     gene            1..1217
                     /gene="Opn1mw"
                     /note="opsin 1, medium wave sensitive"
                     /db_xref="GeneID:89810"
                     /db_xref="RGD:620978"
     exon            1..137
                     /gene="Opn1mw"
                     /inference="alignment:Splign:2.1.0"
     CDS             41..1120
                     /gene="Opn1mw"
                     /note="green-sensitive opsin; green cone photoreceptor
                     pigment; medium wavelength-sensitive cone opsin; opsin 1
                     (cone pigments), medium-wave-sensitive (color blindness,
                     deutan), green opsin"
                     /codon_start=1
                     /product="medium-wave-sensitive opsin 1"
                     /protein_id="NP_446000.1"
                     /db_xref="GeneID:89810"
                     /db_xref="RGD:620978"
                     /translation="MAQQLTGEQTLDHYEDSTQASIFTYTNSNSTRGPFEGPNYHIAP
                     RWVYHLTSTWMILVVIASVFTNGLVLAATMRFKKLRHPLNWILVNLAVADLAETIIAS
                     TISVVNQIYGYFVLGHPLCVIEGYIVSLCGITGLWSLAIISWERWLVVCKPFGNVRFD
                     AKLATVGIVFSWVWAAVWTAPPIFGWSRYWPYGLKTSCGPDVFSGTSYPGVQSYMMVL
                     MVTCCIFPLSIIVLCYLQVWLAIRAVAKQQKESESTQKAEKEVTRMVVVMVFAYCLCW
                     GPYTFFACFATAHPGYAFHPLVASLPSYFAKSATIYNPIIYVFMNRQFRNCILQLFGK
                     KVDDSSELSSTSKTEVSSVSSVSPA"
     exon            138..434
                     /gene="Opn1mw"
                     /inference="alignment:Splign:2.1.0"
     exon            435..603
                     /gene="Opn1mw"
                     /inference="alignment:Splign:2.1.0"
     exon            604..769
                     /gene="Opn1mw"
                     /inference="alignment:Splign:2.1.0"
     exon            770..1009
                     /gene="Opn1mw"
                     /inference="alignment:Splign:2.1.0"
     exon            1010..1217
                     /gene="Opn1mw"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tgccaagtct gacaggttcc agagacagtt ttccacagcc atggcccaac agcttacagg
       61 tgaacagaca ctggaccatt atgaggatag cacccaggca agcatcttca cctataccaa
      121 cagcaacagc accagaggtc cctttgaagg tcccaattat cacattgctc caaggtgggt
      181 gtaccacctc accagcacct ggatgattct tgtggtcatt gcatctgtct tcacaaatgg
      241 actcgtgctg gcagccacca tgaggttcaa gaagctgcgt catcctctga actggattct
      301 agtgaacttg gcagttgctg acctagcaga gaccattatt gccagcacta tcagtgttgt
      361 gaaccaaatc tatggctact ttgtgctggg ccaccctctg tgtgtcatag aaggctacat
      421 tgtctcacta tgtgggatca caggcctctg gtccttggcc atcatttcct gggagagatg
      481 gctggtggtc tgcaagccct ttggcaatgt gagatttgat gctaaactgg ccactgtggg
      541 aatcgtcttc tcctgggtct gggctgctgt atggacggcc ccaccaatct ttggttggag
      601 caggtactgg ccttatggcc tgaagacatc gtgtggtcca gacgtgttca gcggtacctc
      661 gtatcctggg gttcagtctt atatgatggt cctcatggtc acgtgctgca tcttcccact
      721 cagcatcatc gtgctctgct acctccaagt gtggctggcc atccgagcag tggcaaagca
      781 acagaaagaa tctgagtcca cccagaaggc tgagaaggag gtgacacgca tggtggtggt
      841 gatggtcttc gcatactgcc tctgctgggg gccctatact ttctttgcat gctttgctac
      901 tgcccatcct ggctatgcct tccaccctct tgtggcctcc ctaccatcct actttgccaa
      961 aagtgccact atctacaatc ccattatcta tgtctttatg aaccggcagt ttcgaaattg
     1021 catcttacag ctctttggaa agaaagttga tgatagctct gaactttcca gcacctccaa
     1081 aacagaagtc tcatctgtct cttcagtgtc acctgcataa agtttgcctc caacctgttg
     1141 catctaccaa agctttggcc atgtcccttc tcatccatcc taatgaaata aacataattt
     1201 ctccttgccc aaaccat
//
