LOCUS       NM_053573               2759 bp    mRNA    linear   ROD 04-FEB-2024
DEFINITION  Rattus norvegicus olfactomedin 1 (Olfm1), mRNA.
ACCESSION   NM_053573
VERSION     NM_053573.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2759)
  AUTHORS   Sultana,A., Nakaya,N., Dong,L., Abu-Asab,M., Qian,H. and
            Tomarev,S.I.
  TITLE     Deletion of olfactomedin 2 induces changes in the AMPA receptor
            complex and impairs visual, olfactory, and motor functions in mice
  JOURNAL   Exp Neurol 261, 802-811 (2014)
   PUBMED   25218043
REFERENCE   2  (bases 1 to 2759)
  AUTHORS   Rice,H.C., Townsend,M., Bai,J., Suth,S., Cavanaugh,W., Selkoe,D.J.
            and Young-Pearse,T.L.
  TITLE     Pancortins interact with amyloid precursor protein and modulate
            cortical cell migration
  JOURNAL   Development 139 (21), 3986-3996 (2012)
   PUBMED   22992957
REFERENCE   3  (bases 1 to 2759)
  AUTHORS   Nakaya,N., Sultana,A., Lee,H.S. and Tomarev,S.I.
  TITLE     Olfactomedin 1 interacts with the Nogo A receptor complex to
            regulate axon growth
  JOURNAL   J Biol Chem 287 (44), 37171-37184 (2012)
   PUBMED   22923615
REFERENCE   4  (bases 1 to 2759)
  AUTHORS   Schwenk,J., Harmel,N., Brechet,A., Zolles,G., Berkefeld,H.,
            Muller,C.S., Bildl,W., Baehrens,D., Huber,B., Kulik,A., Klocker,N.,
            Schulte,U. and Fakler,B.
  TITLE     High-resolution proteomics unravel architecture and molecular
            diversity of native AMPA receptor complexes
  JOURNAL   Neuron 74 (4), 621-633 (2012)
   PUBMED   22632720
REFERENCE   5  (bases 1 to 2759)
  AUTHORS   Wang,L., Gao,X., Gao,P., Deng,W., Yu,P., Ma,J., Guo,J., Wang,X.,
            Cheng,H., Zhang,C., Yu,C., Ma,X., Lv,B., Lu,Y., Shi,T. and Ma,D.
  TITLE     Cell-based screening and validation of human novel genes associated
            with cell viability
  JOURNAL   J Biomol Screen 11 (4), 369-376 (2006)
   PUBMED   16751333
REFERENCE   6  (bases 1 to 2759)
  AUTHORS   Ando,K., Nagano,T., Nakamura,A., Konno,D., Yagi,H. and Sato,M.
  TITLE     Expression and characterization of disulfide bond use of
            oligomerized A2-Pancortins: extracellular matrix constituents in
            the developing brain
  JOURNAL   Neuroscience 133 (4), 947-957 (2005)
   PUBMED   15927402
REFERENCE   7  (bases 1 to 2759)
  AUTHORS   Danielson,P.E., Forss-Petter,S., Battenberg,E.L., deLecea,L.,
            Bloom,F.E. and Sutcliffe,J.G.
  TITLE     Four structurally distinct neuron-specific olfactomedin-related
            glycoproteins produced by differential promoter utilization and
            alternative mRNA splicing from a single gene
  JOURNAL   J Neurosci Res 38 (4), 468-478 (1994)
   PUBMED   7932877
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from U03417.1.
            
            [WARNING] On Apr 23, 2024 this sequence was replaced by
            NM_053573.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: U03417.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2759
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="Sprague-Dawley"
                     /db_xref="taxon:10116"
                     /chromosome="3"
                     /map="3p12"
     gene            1..2759
                     /gene="Olfm1"
                     /gene_synonym="D2Sut1e; Noe1"
                     /note="olfactomedin 1"
                     /db_xref="GeneID:93667"
                     /db_xref="RGD:620320"
     exon            1..441
                     /gene="Olfm1"
                     /gene_synonym="D2Sut1e; Noe1"
                     /inference="alignment:Splign:2.1.0"
     CDS             292..1749
                     /gene="Olfm1"
                     /gene_synonym="D2Sut1e; Noe1"
                     /note="noelin; 1B426B; pancortin; neuronal
                     olfactomedin-related ER localized protein; olfactomedin
                     related ER localized protein"
                     /codon_start=1
                     /product="noelin precursor"
                     /protein_id="NP_446025.1"
                     /db_xref="GeneID:93667"
                     /db_xref="RGD:620320"
                     /translation="MSVPLLKIGVVLSTMAMITNWMSQTLPSLVGLNTTRLSAASGGT
                     LDRSTGVLPTNPEESWQVYSSAQDSEGRCICTVVAPQQTMCSRDARTKQLRQLLEKVQ
                     NMSQSIEVLDRRTQRDLQYVEKMENQMKGLESKFRQVEESHKQHLARQFKAIKAKMDE
                     LRPLIPVLEEYKADAKLVLQFKEEVQNLTSVLNELQEEIGAYDYDELQSRVSNLEERL
                     RACMQKLACGKLTGISDPVTVKTSGSRFGSWMTDPLAPEGDNRVWYMDGYHNNRFVRE
                     YKSMVDFMNTDNFTSHRLPHPWSGTGQVVYNGSIYFNKFQSHIIIRFDLKTETILKTR
                     SLDYAGYNNMYHYAWGGHSDIDLMVDENGLWAVYATNQNAGNIVISKLDPVSLQILQT
                     WNTSYPKRSAGEAFIICGTLYVTNGYSGGTKVHYAYQTNASTYEYIDIPFQNKYSHIS
                     MLDYNPKDRALYAWNNGHQTLYNVTLFHVIRSDEL"
     exon            442..591
                     /gene="Olfm1"
                     /gene_synonym="D2Sut1e; Noe1"
                     /inference="alignment:Splign:2.1.0"
     exon            592..747
                     /gene="Olfm1"
                     /gene_synonym="D2Sut1e; Noe1"
                     /inference="alignment:Splign:2.1.0"
     exon            748..967
                     /gene="Olfm1"
                     /gene_synonym="D2Sut1e; Noe1"
                     /inference="alignment:Splign:2.1.0"
     exon            968..1074
                     /gene="Olfm1"
                     /gene_synonym="D2Sut1e; Noe1"
                     /inference="alignment:Splign:2.1.0"
     exon            1075..2759
                     /gene="Olfm1"
                     /gene_synonym="D2Sut1e; Noe1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 aacctggtgg cccttctcga cagcggagcg cgcggggacg ctgcagcggc gggcaacgcg
       61 ggcaggcagc gcgctccagg cagggccgcc tggtcacctc ccggcgccgg ggcggcgcgg
      121 cgatggccag ggcgcagagg gaggcagaga ccggcgggcg acggcgggcg gagggggcgc
      181 ggggacgcgg ccgggcgccc ctgcccgccc tggtgcccgc cgcctaaggc tgcccggggc
      241 gcgggagccg gcgccggcgc ggcgcgggcg caggagacca ctcgaggcgc gatgtcggtg
      301 ccgctgctga agatcggggt cgtgctaagc accatggcca tgatcaccaa ctggatgtcc
      361 cagacgctgc cctcgctggt gggcctcaat accacccggc tctcggccgc cagcggcggg
      421 acgctggacc gcagcaccgg cgtgttgccc accaaccccg aggagagctg gcaggtgtac
      481 agctctgccc aggacagtga gggcaggtgt atctgcacgg tggtcgcccc ccagcagacc
      541 atgtgttcac gggatgcccg cacaaaacag ctgaggcagc tactggagaa ggtgcaaaac
      601 atgtctcaat ccatagaagt cttggacagg cggactcaga gagacctgca gtacgtggag
      661 aagatggaga accagatgaa aggcctggag tccaagttca ggcaggtgga ggagagccat
      721 aagcagcatc tggccaggca gttcaaggca ataaaagcga aaatggatga acttaggcct
      781 ttgattcctg tgttggaaga gtacaaggcc gatgccaaat tggtattgca gtttaaggag
      841 gaggtccaga atctgacgtc agtgcttaac gaactgcaag aggaaattgg cgcctatgac
      901 tacgatgaac ttcagagcag agtgtccaat cttgaagaaa ggctccgtgc atgcatgcaa
      961 aaactagcct gcgggaagct gacaggcata agtgacccgg tgactgtcaa gacctcaggc
     1021 tcaaggttcg ggtcctggat gacagaccca ctggccccag aaggtgataa ccgggtctgg
     1081 tacatggatg gttatcacaa caaccgcttt gtccgtgagt acaagtccat ggtggacttc
     1141 atgaacacgg ataattttac ctcgcaccgt ctcccacacc cctggtcggg cacgggccag
     1201 gtggtctaca atggctccat ctatttcaac aaattccaga gtcacattat cattaggttt
     1261 gacctgaaga cagagacgat cctgaagacg cggagcctgg actacgctgg ctacaacaac
     1321 atgtaccact atgcctgggg cggccactca gacatcgacc tcatggtgga cgagaacggg
     1381 ctctgggccg tctacgccac aaaccagaac gcaggcaaca ttgtcatcag caagctggat
     1441 cctgtctcac tgcaaatcct ccagacctgg aacaccagct accccaagcg cagcgccggc
     1501 gaggccttca tcatctgcgg caccctctac gtcaccaacg gttactcggg gggcaccaag
     1561 gtccactatg cctaccaaac caacgcctcg acctacgagt acattgacat ccccttccag
     1621 aacaaatact ctcacatctc catgctggac tacaacccta aagaccgcgc gctgtacgcc
     1681 tggaacaacg gccatcagac cctctacaac gtcaccctct tccacgtcat ccgctccgat
     1741 gagttgtagc tcccgctttt ccagaagcca agggtccaag tcctcacccc gaggacattt
     1801 tccataaaac agctgccaaa tgattccaag aatactataa cagtcctgat tttgagaaat
     1861 cagcgcaatt ttgacgccga gagatggtgt cctctctgtg ttcctcctgc tcgtgcaggt
     1921 gggccacaga tttcagaaga aaccgccatg tatgtggatg gaactgcagc ccaaggctcc
     1981 ttggctgtcc ccatcccacc ccatccctct ctggtccaat aactcaaaga agcaaggcga
     2041 tgactgttgg cccctctcac ccaagaacaa cccactgcta agattgcatg gacatttcct
     2101 taggtcgtgc ccagcgagat gacgtgatgg ccattctccc cacccacagc ccccagcccc
     2161 cgtggcgctc ggtgtaggct gcttcggccc acacgtatcg cagctgcctt tttcttgact
     2221 gtgttgttgt ctcttagatt aactgtgctg agactcccgg tagctcatgg acctgtgtct
     2281 agtactttcc cgaagcgatg gtgggtgtgc gtagagtgaa gttgctgtac ccacgttgtt
     2341 gaacttgcgt accctgtagc tagatcgtga ggtgtccgtc tgttatcccc cccaaggtgg
     2401 taactccgtg tgttcaattt atgcaatgaa tgttgtcatg cgatgctgta gtttggattg
     2461 ataagtggat ggtttctgtt tctaaaaaga aaaaaaaatc agtgttcgcc cttataggag
     2521 acatagtcaa gttcatgttg ataataaccc agtgaaattc ttctcttgtc aagttatctg
     2581 aattgtgtaa ccatagatgg gaaggacgca tcttgggaaa cttcagtttc ctacgggaag
     2641 gaactcccca agggcagcca tgtgtgaaaa gatcattttt taaagaaaaa aaaaataagt
     2701 caaagagggc aactttgtac tattcagtta tctaaggaac aataaagata ttaggagat
//
