LOCUS       NM_001107411            5421 bp    mRNA    linear   ROD 08-APR-2024
DEFINITION  Rattus norvegicus 2-oxoglutarate and iron-dependent oxygenase
            domain containing 1 (Ogfod1), mRNA.
ACCESSION   NM_001107411 XM_001062833 XM_226262
VERSION     NM_001107411.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 5421)
  AUTHORS   Loenarz,C., Sekirnik,R., Thalhammer,A., Ge,W., Spivakovsky,E.,
            Mackeen,M.M., McDonough,M.A., Cockman,M.E., Kessler,B.M.,
            Ratcliffe,P.J., Wolf,A. and Schofield,C.J.
  TITLE     Hydroxylation of the eukaryotic ribosomal decoding center affects
            translational accuracy
  JOURNAL   Proc Natl Acad Sci U S A 111 (11), 4019-4024 (2014)
   PUBMED   24550462
REFERENCE   2  (bases 1 to 5421)
  AUTHORS   Singleton,R.S., Liu-Yi,P., Formenti,F., Ge,W., Sekirnik,R.,
            Fischer,R., Adam,J., Pollard,P.J., Wolf,A., Thalhammer,A.,
            Loenarz,C., Flashman,E., Yamamoto,A., Coleman,M.L., Kessler,B.M.,
            Wappner,P., Schofield,C.J., Ratcliffe,P.J. and Cockman,M.E.
  TITLE     OGFOD1 catalyzes prolyl hydroxylation of RPS23 and is involved in
            translation control and stress granule formation
  JOURNAL   Proc Natl Acad Sci U S A 111 (11), 4031-4036 (2014)
   PUBMED   24550447
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000019.1.
            
            On Sep 13, 2022 this sequence version replaced NM_001107411.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643297.50933.1,
                                           SRR26643299.63755.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760386 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-190               JAXUCZ010000019.1  10980330-10980519   c
            191-336             JAXUCZ010000019.1  10978649-10978794   c
            337-383             JAXUCZ010000019.1  10972140-10972186   c
            384-484             JAXUCZ010000019.1  10967554-10967654   c
            485-601             JAXUCZ010000019.1  10964953-10965069   c
            602-693             JAXUCZ010000019.1  10964319-10964410   c
            694-822             JAXUCZ010000019.1  10963999-10964127   c
            823-936             JAXUCZ010000019.1  10963505-10963618   c
            937-1016            JAXUCZ010000019.1  10961402-10961481   c
            1017-1330           JAXUCZ010000019.1  10960827-10961140   c
            1331-1453           JAXUCZ010000019.1  10955916-10956038   c
            1454-1512           JAXUCZ010000019.1  10955493-10955551   c
            1513-5421           JAXUCZ010000019.1  10950950-10954858   c
FEATURES             Location/Qualifiers
     source          1..5421
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="19"
                     /map="19p12"
     gene            1..5421
                     /gene="Ogfod1"
                     /gene_synonym="RGD1308848"
                     /note="2-oxoglutarate and iron-dependent oxygenase domain
                     containing 1"
                     /db_xref="GeneID:307657"
                     /db_xref="RGD:1308848"
     exon            1..190
                     /gene="Ogfod1"
                     /gene_synonym="RGD1308848"
                     /inference="alignment:Splign:2.1.0"
     CDS             37..1674
                     /gene="Ogfod1"
                     /gene_synonym="RGD1308848"
                     /EC_number="1.14.11.-"
                     /note="2-oxoglutarate and iron-dependent oxygenase
                     domain-containing protein 1"
                     /codon_start=1
                     /product="prolyl 3-hydroxylase OGFOD1"
                     /protein_id="NP_001100881.1"
                     /db_xref="GeneID:307657"
                     /db_xref="RGD:1308848"
                     /translation="MNGKRPADPGPARPMKKGKKQVAAEFSDAVTEEILRKQVAEAWS
                     CRTPFSHEAIALDMDPFLHCVIPNFIQSQDFLEGLQKELLSLDFHEKYNDLYKFQQSD
                     DLKKRKEPHISALRTLMFEDFRAWLSKVSGIDLEATVDMSCAKYEFTDALLCHDDELE
                     GRRIAFILYLVPSWDRDLGGTLDLYDTDEHLQPKQIVKSLVPAWNKLVFFEVSPVSFH
                     QVSEVLSEELTRLSISGWFHGPSLARPPTYFEPPVPRSPHIPQDHEILYEWINPAYLE
                     MDYQMQIQEEFEERSEILLKEFLKPEKFAKVCEALEKGDVEWKSHGPPNKRFYEKAKE
                     SNLPDVLKECMGLFHSEAMFLLLSNFTGLKLHFLAPSEDDETEDKGEGETASAAGGTE
                     EGTSQSPPGPEDNQAAVGSHSQENGEQADPEPQEDEAKKESSVPMCQGELRRWKTGHY
                     TLVHDNSKTEFALDLFLYCGCEGWEPEYGGFTSYIAKGEDEELLIVNPENNALALVYR
                     DRETLRFVKHINHRSLEQRNTFPNRSGFWDFAFMYYE"
     exon            191..336
                     /gene="Ogfod1"
                     /gene_synonym="RGD1308848"
                     /inference="alignment:Splign:2.1.0"
     exon            337..383
                     /gene="Ogfod1"
                     /gene_synonym="RGD1308848"
                     /inference="alignment:Splign:2.1.0"
     exon            384..484
                     /gene="Ogfod1"
                     /gene_synonym="RGD1308848"
                     /inference="alignment:Splign:2.1.0"
     exon            485..601
                     /gene="Ogfod1"
                     /gene_synonym="RGD1308848"
                     /inference="alignment:Splign:2.1.0"
     exon            602..693
                     /gene="Ogfod1"
                     /gene_synonym="RGD1308848"
                     /inference="alignment:Splign:2.1.0"
     exon            694..822
                     /gene="Ogfod1"
                     /gene_synonym="RGD1308848"
                     /inference="alignment:Splign:2.1.0"
     exon            823..936
                     /gene="Ogfod1"
                     /gene_synonym="RGD1308848"
                     /inference="alignment:Splign:2.1.0"
     exon            937..1016
                     /gene="Ogfod1"
                     /gene_synonym="RGD1308848"
                     /inference="alignment:Splign:2.1.0"
     exon            1017..1330
                     /gene="Ogfod1"
                     /gene_synonym="RGD1308848"
                     /inference="alignment:Splign:2.1.0"
     exon            1331..1453
                     /gene="Ogfod1"
                     /gene_synonym="RGD1308848"
                     /inference="alignment:Splign:2.1.0"
     exon            1454..1512
                     /gene="Ogfod1"
                     /gene_synonym="RGD1308848"
                     /inference="alignment:Splign:2.1.0"
     exon            1513..5421
                     /gene="Ogfod1"
                     /gene_synonym="RGD1308848"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tgacttcctc ggcgtgggtc tgtgcatggt gagaagatga acgggaaacg gccggcagat
       61 cccggcccag cgcggccaat gaagaaggga aagaagcagg tagcggcaga attttcggac
      121 gctgtcactg aagaaatcct gaggaagcag gtggccgagg cctggagctg ccggacgccg
      181 ttcagtcatg aagcaattgc cttggacatg gatccttttc ttcactgtgt gatcccaaac
      241 ttcatccaaa gccaagactt cctggaagga cttcagaaag aactcttgag cctggacttc
      301 catgaaaagt acaatgattt atataagttc cagcagtccg atgatttgaa gaagagaaaa
      361 gagcctcata tctcagcctt gaggacactt atgtttgaag attttcgggc ctggctttct
      421 aaggtttccg gcattgacct agaagcaacc gttgacatgt cctgtgctaa atacgagttc
      481 actgatgctc tgctctgcca cgacgacgag ctggaggggc gccggatcgc cttcattctg
      541 tacctggttc cttcctggga cagggacttg gggggcaccc tggacctcta tgacacggat
      601 gaacacttgc agccaaagca gattgtgaag tctcttgtcc ctgcctggaa caaactggtt
      661 ttctttgaag tgtctccagt atcctttcac caggtgtctg aagtcctgtc tgaagaatta
      721 acacgtttgt ccataagtgg ctggtttcac ggtccttcgt tagccaggcc tcccacctac
      781 tttgagcccc cagtccctcg aagccctcac atcccacaag accatgaaat tttatacgag
      841 tggatcaacc ctgcttacct ggaaatggat tatcaaatgc aaattcagga agaatttgag
      901 gaaaggtctg aaattctcct gaaggagttt cttaagcctg agaaatttgc aaaggtctgt
      961 gaagccttgg agaaaggaga tgtggaatgg aaaagccatg gtcccccaaa caaaaggttt
     1021 tatgagaaag cgaaggaaag taacctccct gatgttctga aggagtgcat gggcctgttt
     1081 cactcagagg caatgttcct gctgctctcc aacttcaccg ggctgaagct tcacttcttg
     1141 gccccttcag aagatgatga gaccgaggac aaaggagagg gggagacagc cagcgctgct
     1201 ggtggcactg aagaagggac tagccaaagc cccccagggc cagaggataa tcaggcagct
     1261 gtcggcagcc acagtcaaga gaatggtgaa caggcagacc cagaaccaca ggaagacgaa
     1321 gcaaagaaag aatcaagtgt tcccatgtgc cagggagagc tgaggcgatg gaaaactggt
     1381 cactacactt tagtccacga caacagcaag acggagtttg ccttggacct gtttctgtac
     1441 tgcggctgtg aaggctggga gccagagtat ggcggcttca cctcctacat tgcgaaaggt
     1501 gaagatgaag agctgctcat agtgaatcca gaaaacaatg ctctggcctt ggtctacaga
     1561 gacagagaaa ctctgagatt tgtgaagcac attaaccacc gcagcctaga gcagaggaac
     1621 accttcccaa acagaagcgg gttctgggac ttcgcattca tgtactacga gtaacaagac
     1681 tgggcagggc cagctagcat tcgctccacc agtgctggga acgtgtgggg gaagggaagc
     1741 gcgcatgctg ggtaactaag tgccctcctt acaggctgcc ctgtgctggt gcacgcctgt
     1801 aatgccagcc tcaggaggca gaggaagggg accttcagtt ccaaggtcag tgtggcttag
     1861 acagtgctac tgtctcccca aacatacaaa tcttggtcat cctctcataa aagtcatgat
     1921 tgtcctcaaa ctagacatca tgctggagct atgaactttt cccttggttt ttaaaaactg
     1981 gtttacccca tttgaattct tttggttcta tagtaactgc cttggcaact ttctaacttt
     2041 ggtgattttt ttttttaatt tatggttaaa tacacacaca cacccataca caatttagca
     2101 ggataacact tgtttttggt ttgaggcggg ggggtttgtt ttgttctttt gacagggttt
     2161 tactatgtag cccaggctag ctctgaaata ctgatccttc cacctcaact cctaagtgct
     2221 gggattgcag gcctgagccg ccacccccac aattcctgca cgtatagtcc gtggggttga
     2281 gcacactgaa gtgcaaagca cccatcactg ccgtatccgg gtgttttccg tcttcccaaa
     2341 gggaaatgct gcttggtccc ttctctgtcg actttttgcc tcaccagtga tccatacagt
     2401 gtggatcact tcctaattag cttgtttcac ttagcacagc gccctcaggg tccatcagtg
     2461 tttccagtgt ttttctttct cactccttcc taagtagtgg tagaaacctt gtgtaaccct
     2521 cttcgtgctg aacctgagag ctgtgacaca gtctgagtca tgacttgcac tgtgggctga
     2581 gctccaccct gactcccagg acagggtgca ctcccatagc tagcgctgct cccttggaaa
     2641 gatctggctg gaagctaaca cagccccagg aatcctgtgg ctgtttactg ccctgttttc
     2701 cccctcatct actgccttta aacctggaac catgacttct ctgagtctag cctcccagtt
     2761 actgtgtgtt cctaaatgct ggaggaccgg gtgtgaaagg agttgccttt tccttccttt
     2821 tgaaagaccc catgttaaag gcagtgccag gaggataaga agtcctcctt ttgcttctgt
     2881 ccttttccat gaactgctcc atgggactat ggcatagctc ttcccatttt gtgggggtgt
     2941 gcttggtggc tgaaagatgt cctcaccacc ccacaccaca ttcctttgct gctttctcgt
     3001 tttctgacta tccttgtggc tttcagtatg gactttacct attagtagga aaagcgctgg
     3061 acctttaaag tggcttcttc acacttctct ttgacgtcct aaaagtccat ccaaatgcat
     3121 tgtcttttag attgatggct ttcaatttat ttaccccagt cagttaaaca catttaacat
     3181 tcatacccta atggatactt agaagtttat atgttctggg tttaatcata aaacaaagtc
     3241 attcttaaat aatgacacga gaatacccag gcctaaactg agggggtata ctttaatccc
     3301 atgcttttgg aaggtaaagg caagaagatc aagagttcaa gactatcctc agccacacag
     3361 caagttcaag accaacctgg gtaacaatac accttgtctc aaaaacaagt atcaagccag
     3421 gagtgggagg tacacatctt atcccagcac tcaggaggca gaggcaggca gatctgtgga
     3481 ttcaggccag cctggtctac aaagagattt gaggatagcc agagctacat agtgagaccc
     3541 tgattcagga atcaaaaaca aaggaagact atgcagacct ggctttagag ttgacttccc
     3601 atgccaggca gccatggctg tggcccacgc atcctgtttg agacgtcacc gcactttaaa
     3661 acagagtagc gctcacacag gactgcacac gctttgttgc taatgctcca ttttgaagtt
     3721 tgccttttct gaactgctgc aggctaaagg cagaccccgc tctcccccag ttgaagtgcc
     3781 tgattggaaa gacctctgaa ggggcctttc tgtgtctgca gagcccctgg cctgcaagtg
     3841 acggaacctg caggctgctt ttctgctcta aggagcagct gctcctttaa gttgccgtga
     3901 gccacattgt cgtgtctgtg agatgactgg cgtgtgtgac cgtgtgtgtg ggcccgttaa
     3961 gtctccagtg gagctgaaag gttcctgttc cagaacgggc cactgtgctg ccaccggtaa
     4021 gagcgcagcc caggccacct gtgctgccac cggtaagggc gcagcccagg cagttgtgca
     4081 cacagctgtg gccagcaggc caccctcatg cgctcgctca cgttacctgc tcagagtgca
     4141 ctgctgttac ggcggtaact cccatgtgct tcgggcaggt ccttcagaga ggactcaggg
     4201 aaaggcatgg ctctggggtt ggcacttctg tgcctgttac tacccatgca gaccacagta
     4261 gacaaaccac acaggtagaa ggcagtgatg atgacgacaa tcataggtgt gtgtgtgtgt
     4321 gtgtgtgtgt gtgtgtgtgt gtgtgtgtgt gtgctcgtgc atgtgtgcgt gcgtgcgtgc
     4381 gtgcatcaga aaggtttaaa aagaaaataa aggaaatatt tttgtagcta tacaatgtaa
     4441 agttataagt taaagtccta aaaattaaag tgtaaagtaa gttctactgt gtgagttaag
     4501 gctgttgaat agagtatttt taacatttaa catgtcgtcc atgttggaag gcagacagct
     4561 tccgattgtc tctccaagtg cactgtcggg tttgcacagt ggccatgcct ccgcttgcaa
     4621 ttacttgatc ctgattggtt gctgctttgg gcctggggca agagagtcga atgtaggctc
     4681 tcaatgtctt ttcttggtaa aagctatgct aatttctgtg tgaccaatag catgtctctc
     4741 aataatgagc ctctaattct tgttttctta tttattggtg tttttgagaa gggtctctgt
     4801 aggccctagc tctccaactg ctaagattac agagtaccac tgtgtctagc tgtgaacttc
     4861 cagttcttat aactcttttt cctaaaggtg atattccctc caaagacaac agctttatat
     4921 ctcttcagac tatagataat gcatgttcat tgttgagaaa ttaaaagtgt ggaaaaacac
     4981 aaaggtcaat tgaaatccac catcctgtga cagtcgtgtg ttgctgtaac cgtgtcaacg
     5041 tggccaccct acactgtatt aggaaacacg gctcctcttc gttctctctt ccctgtcttc
     5101 tgtccggcaa ataaatacaa ggttacaggg cagtttgtca gacagggctc agagggagac
     5161 actaatggcc accactgcat acaagaatga gaatggtccc tcagggggtc cttaagcgag
     5221 tgtctttcag gtttcttagg gatgaaaatg agcagccaga gatgctcttg gagatctgtg
     5281 tcccactaat gctgcccgac tggtaccctc ctttacattt gtgtttcctt aatataaatg
     5341 tttacacata tatttgagtg attaagaaaa tggatctata tttccggttt tcctcacaaa
     5401 ataaagatgt ttgtgcattt c
//
