LOCUS       NM_017213               2365 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus outer dense fiber of sperm tails 2 (Odf2),
            transcript variant 2, mRNA.
ACCESSION   NM_017213
VERSION     NM_017213.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2365)
  AUTHORS   Wang,C., Li,J., Takemaru,K.I., Jiang,X., Xu,G. and Wang,B.
  TITLE     Centrosomal protein Dzip1l binds Cby, promotes ciliary bud
            formation, and acts redundantly with Bromi to regulate ciliogenesis
            in the mouse
  JOURNAL   Development 145 (6) (2018)
   PUBMED   29487109
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2365)
  AUTHORS   Huang,N., Xia,Y., Zhang,D., Wang,S., Bao,Y., He,R., Teng,J. and
            Chen,J.
  TITLE     Hierarchical assembly of centriole subdistal appendages via
            centrosome binding proteins CCDC120 and CCDC68
  JOURNAL   Nat Commun 8, 15057 (2017)
   PUBMED   28422092
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 2365)
  AUTHORS   Zhang,Z., Li,W., Zhang,Y., Zhang,L., Teves,M.E., Liu,H.,
            Strauss,J.F. 3rd, Pazour,G.J., Foster,J.A., Hess,R.A. and Zhang,Z.
  TITLE     Intraflagellar transport protein IFT20 is essential for male
            fertility and spermiogenesis in mice
  JOURNAL   Mol Biol Cell 27 (23), 3705-3716 (2016)
   PUBMED   27682589
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   4  (bases 1 to 2365)
  AUTHORS   Wang,X., Wei,Y., Fu,G., Li,H., Saiyin,H., Lin,G., Wang,Z., Chen,S.
            and Yu,L.
  TITLE     Tssk4 is essential for maintaining the structural integrity of
            sperm flagellum
  JOURNAL   Mol Hum Reprod 21 (2), 136-145 (2015)
   PUBMED   25361759
REFERENCE   5  (bases 1 to 2365)
  AUTHORS   Veleri,S., Manjunath,S.H., Fariss,R.N., May-Simera,H., Brooks,M.,
            Foskett,T.A., Gao,C., Longo,T.A., Liu,P., Nagashima,K.,
            Rachel,R.A., Li,T., Dong,L. and Swaroop,A.
  TITLE     Ciliopathy-associated gene Cc2d2a promotes assembly of subdistal
            appendages on the mother centriole during cilia biogenesis
  JOURNAL   Nat Commun 5, 4207 (2014)
   PUBMED   24947469
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 2365)
  AUTHORS   Donkor,F.F., Monnich,M., Czirr,E., Hollemann,T. and Hoyer-Fender,S.
  TITLE     Outer dense fibre protein 2 (ODF2) is a self-interacting
            centrosomal protein with affinity for microtubules
  JOURNAL   J Cell Sci 117 (Pt 20), 4643-4651 (2004)
   PUBMED   15340007
  REMARK    GeneRIF: Data demonstrate that outer dense fibre protein 2 is a
            self-interacting protein that forms a fibrillar structure partially
            linked to the microtubule network.
REFERENCE   7  (bases 1 to 2365)
  AUTHORS   Sun,X.D., Yu,Z.R., Ma,J., Ge,Y.H., Li,S., Xue,S.P. and Han,D.S.
  TITLE     [Characterization of expression of the centrosomal protein,
            Cenexin, in rat spermatogenesis]
  JOURNAL   Shi Yan Sheng Wu Xue Bao 35 (1), 21-25 (2002)
   PUBMED   15344312
  REMARK    GeneRIF: The results suggested that the expression pattern of
            cenexin in rat spermatogenesis might be related to the initiation
            of the flagella formation.
REFERENCE   8  (bases 1 to 2365)
  AUTHORS   Schalles,U., Shao,X., van der Hoorn,F.A. and Oko,R.
  TITLE     Developmental expression of the 84-kDa ODF sperm protein:
            localization to both the cortex and medulla of outer dense fibers
            and to the connecting piece
  JOURNAL   Dev Biol 199 (2), 250-260 (1998)
   PUBMED   9698445
REFERENCE   9  (bases 1 to 2365)
  AUTHORS   Turner,K.J., Sharpe,R.M., Gaughan,J., Millar,M.R., Foster,P.M. and
            Saunders,P.T.
  TITLE     Expression cloning of a rat testicular transcript abundant in germ
            cells, which contains two leucine zipper motifs
  JOURNAL   Biol Reprod 57 (5), 1223-1232 (1997)
   PUBMED   9369191
REFERENCE   10 (bases 1 to 2365)
  AUTHORS   Brohmann,H., Pinnecke,S. and Hoyer-Fender,S.
  TITLE     Identification and characterization of new cDNAs encoding outer
            dense fiber proteins of rat sperm
  JOURNAL   J Biol Chem 272 (15), 10327-10332 (1997)
   PUBMED   9092585
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000003.1.
            
            On Jan 4, 2022 this sequence version replaced NM_017213.2.
            
            Transcript Variant: This variant (2) has an alternate 5' sequence
            including UTR and coding region, as compared to variant 1. The
            resulting isoform (2) has a shorter and different N-terminus, as
            compared to isoform 1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC078857.1, SRR26360186.669466.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-138               JAXUCZ010000003.1  33559674-33559811
            139-375             JAXUCZ010000003.1  33560365-33560601
            376-466             JAXUCZ010000003.1  33561832-33561922
            467-535             JAXUCZ010000003.1  33563076-33563144
            536-706             JAXUCZ010000003.1  33573346-33573516
            707-867             JAXUCZ010000003.1  33574611-33574771
            868-997             JAXUCZ010000003.1  33575676-33575805
            998-1129            JAXUCZ010000003.1  33576314-33576445
            1130-1201           JAXUCZ010000003.1  33583501-33583572
            1202-1273           JAXUCZ010000003.1  33584898-33584969
            1274-1390           JAXUCZ010000003.1  33585055-33585171
            1391-1576           JAXUCZ010000003.1  33585408-33585593
            1577-1686           JAXUCZ010000003.1  33585910-33586019
            1687-1822           JAXUCZ010000003.1  33588494-33588629
            1823-1933           JAXUCZ010000003.1  33591097-33591207
            1934-2038           JAXUCZ010000003.1  33591328-33591432
            2039-2365           JAXUCZ010000003.1  33592454-33592780
FEATURES             Location/Qualifiers
     source          1..2365
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="3"
                     /map="3p12"
     gene            1..2365
                     /gene="Odf2"
                     /note="outer dense fiber of sperm tails 2"
                     /db_xref="GeneID:29479"
                     /db_xref="RGD:3229"
     exon            1..138
                     /gene="Odf2"
                     /inference="alignment:Splign:2.1.0"
     exon            139..375
                     /gene="Odf2"
                     /inference="alignment:Splign:2.1.0"
     CDS             344..2260
                     /gene="Odf2"
                     /note="isoform 2 is encoded by transcript variant 2; outer
                     dense fiber protein 2; testis-specific autoantigen;
                     cenexin; 84 kDa outer dense fiber protein; outer dense
                     fiber of sperm tails protein 2; sperm outer dense fiber
                     major protein 2; outer dense fiber of sperm tail 2"
                     /codon_start=1
                     /product="outer dense fiber protein 2 isoform 2"
                     /protein_id="NP_058909.2"
                     /db_xref="GeneID:29479"
                     /db_xref="RGD:3229"
                     /translation="MSASSSGGSPRFPSCGKNGVTSLTQKKVLRTPCGAPSVTVTKSH
                     KRGMKGDTVNVRRSVRVKTKNPPHCLEITPPSSEKLVSVMRLSDLSTEDDDSGHCKMN
                     RYDKKIDSLMNAVGCLKSEVKMQKGERQMAKRFLEERKEELEEVAHELAETEHENTVL
                     RHNIERIKEEKDFTMLQKKHLQQEKECLMSKLVEAEMDGAAAAKQVMALKDTIGKLKT
                     EKQMTCTDINTLTRQKELLLQKLSTFEETNRTLRDLLREQHCKEDSERLMEQQGALLK
                     RLAEADSEKARLLLLLQDKDKEVEELLQEIQCEKAQAKTASELSKSMESMRGHLQAQL
                     RCKEAENSRLCMQIKNLERSGNQHKAEVEAIMEQLKELKQKGDRDKETLKKAIRAQKE
                     RAEKSEEYAEQLHVQLADKDLYVAEALSTLESWRSRYNQVVKDKGDLELEIIVLNDRV
                     TDLVNQQQSLEEKMREDRDSLVERLHRQTAEYSAFKLENERLKASFAPMEDKLNQAHL
                     EVQQLKASVKNYEGMIDNYKSQVMKTRLEADEVAAQLERCDKENKMLKDEMNKEIEAA
                     RRQFQSQLADLQQLPDILKITEAKLAECQDQLQGYERKNIDLTAIISDLRSRVRDWQK
                     GSHELARAGARLPR"
     exon            376..466
                     /gene="Odf2"
                     /inference="alignment:Splign:2.1.0"
     exon            467..535
                     /gene="Odf2"
                     /inference="alignment:Splign:2.1.0"
     exon            536..706
                     /gene="Odf2"
                     /inference="alignment:Splign:2.1.0"
     exon            707..867
                     /gene="Odf2"
                     /inference="alignment:Splign:2.1.0"
     exon            868..997
                     /gene="Odf2"
                     /inference="alignment:Splign:2.1.0"
     exon            998..1129
                     /gene="Odf2"
                     /inference="alignment:Splign:2.1.0"
     exon            1130..1201
                     /gene="Odf2"
                     /inference="alignment:Splign:2.1.0"
     exon            1202..1273
                     /gene="Odf2"
                     /inference="alignment:Splign:2.1.0"
     exon            1274..1390
                     /gene="Odf2"
                     /inference="alignment:Splign:2.1.0"
     exon            1391..1576
                     /gene="Odf2"
                     /inference="alignment:Splign:2.1.0"
     exon            1577..1686
                     /gene="Odf2"
                     /inference="alignment:Splign:2.1.0"
     exon            1687..1822
                     /gene="Odf2"
                     /inference="alignment:Splign:2.1.0"
     exon            1823..1933
                     /gene="Odf2"
                     /inference="alignment:Splign:2.1.0"
     exon            1934..2038
                     /gene="Odf2"
                     /inference="alignment:Splign:2.1.0"
     exon            2039..2365
                     /gene="Odf2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ccttcctcct cccgctaacg ggcgggccgg ccgcctccgt cctctccggg ccatcggcag
       61 cgctctttcc ctcctctgct gccctcgggc agggctgcgc ccttctatgg gcagaacccc
      121 gttccctctt gcccgctgga cagttgctgt gcgacttgga cagtagagga gcgcctccca
      181 agttttcatc caactgccac ccccaaagct tccaccctcc tcccctcaga gagaggacgt
      241 ttgatgcccg gcccctgaga ttctcattgg caagcccctc tgggtccccc tgagcagagc
      301 ctgccgaccc aattgcccaa ctttgcggct ttgatgctta gccatgtctg cctcatcctc
      361 aggcggctcc cccaggtttc catcgtgtgg gaagaacgga gtaacgagtc tcacacagaa
      421 aaaagtcttg agaacacctt gtggcgcacc cagtgtaact gtgacgaaat ctcataagcg
      481 cggaatgaaa ggggacaccg tgaatgtacg gcggagtgtc cgggtgaaaa ccaagaatcc
      541 acctcattgc ctggagatca caccaccatc ttcagaaaag ctggtctcgg tgatgcgatt
      601 gagtgacctt tctacagaag acgacgattc tggtcactgt aagatgaacc gttacgataa
      661 gaagattgac agtctaatga acgcggtcgg ttgtctcaaa tctgaggtca agatgcagaa
      721 aggtgaacgc caaatggcca aaaggttcct ggaggagagg aaggaagaac tggaggaggt
      781 agcacatgag cttgcagaga cggagcatga gaacacagtg ctcagacaca acatcgagcg
      841 catcaaggag gagaaggact tcaccatgct tcaaaagaaa cacctccagc aggagaagga
      901 atgcctcatg tccaaactgg tggaggctga aatggatggg gcggctgctg ccaaacaagt
      961 catggccttg aaggatacca tcgggaagct gaaaaccgag aaacagatga cttgcaccga
     1021 catcaacacc ttaacgaggc agaaggaact tctcctgcag aagctgagca cctttgaaga
     1081 gaccaaccgc accctccgag atctgttgag ggagcagcac tgcaaagagg attccgagag
     1141 actaatggag caacaaggtg cattactgaa acgtctggca gaggccgact cagagaaagc
     1201 gcgcctgctg ttactactgc aagacaagga caaggaagtg gaagaactcc tccaggagat
     1261 acaatgtgag aaggctcaag caaagacagc gtctgagctc tccaagtcca tggagtccat
     1321 gcgggggcat ttgcaggcac agcttcgctg caaagaggct gagaacagcc gcctgtgcat
     1381 gcagatcaag aatttagagc gcagtgggaa ccagcacaag gcggaagtag aggccatcat
     1441 ggagcagcta aaggaactga agcaaaaggg agaccgagac aaagagaccc tgaagaaggc
     1501 catccgagcc cagaaggagc gagctgagaa gagtgaggag tatgccgagc agctacatgt
     1561 gcagctggcc gacaaggacc tttatgttgc tgaagcttta tctactctgg agtcatggag
     1621 gagccgttac aaccaagttg tgaaagacaa aggagacctt gagttggaga tcattgtcct
     1681 aaatgaccgg gtgacagatc ttgtaaacca acaacagagc ttggaggaga agatgcggga
     1741 agaccgggac agcttggtag agagactgca ccggcaaact gctgagtatt ctgccttcaa
     1801 gctagagaac gagaggctca aggctagctt tgcccctatg gaggacaagc tcaatcaggc
     1861 tcacttggag gtccagcaac tgaaggcatc agtgaagaac tacgagggga tgatcgacaa
     1921 ctacaagagc caggtgatga aaacaagatt ggaggctgac gaagtggctg cgcagctaga
     1981 gcgctgcgac aaagagaaca agatgcttaa agacgagatg aacaaagaaa tcgaggcggc
     2041 ccgtcggcag ttccagtcac agctggctga cctacaacag ctgcctgaca tcctcaagat
     2101 cacggaggcc aagctggctg agtgtcaaga ccagctgcag ggctacgaga ggaagaacat
     2161 cgacctcaca gccatcattt cagacctgcg cagccgggta agggactggc agaagggatc
     2221 ccacgaactg gcccgagcag gggcccgctt accgagatga gctgcacgcc ccccaaggga
     2281 ggaccacttc ctttttcttg gctgccgatt tctgaaagga gtgagctatc atcagtgctg
     2341 tgaaataaaa gtctggtgtg ccaaa
//
