LOCUS       NM_001399112            2306 bp    mRNA    linear   ROD 27-MAR-2024
DEFINITION  Rattus norvegicus outer dense fiber of sperm tails 2 (Odf2),
            transcript variant 6, mRNA.
ACCESSION   NM_001399112
VERSION     NM_001399112.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2306)
  AUTHORS   Wang,C., Li,J., Takemaru,K.I., Jiang,X., Xu,G. and Wang,B.
  TITLE     Centrosomal protein Dzip1l binds Cby, promotes ciliary bud
            formation, and acts redundantly with Bromi to regulate ciliogenesis
            in the mouse
  JOURNAL   Development 145 (6) (2018)
   PUBMED   29487109
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2306)
  AUTHORS   Huang,N., Xia,Y., Zhang,D., Wang,S., Bao,Y., He,R., Teng,J. and
            Chen,J.
  TITLE     Hierarchical assembly of centriole subdistal appendages via
            centrosome binding proteins CCDC120 and CCDC68
  JOURNAL   Nat Commun 8, 15057 (2017)
   PUBMED   28422092
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 2306)
  AUTHORS   Zhang,Z., Li,W., Zhang,Y., Zhang,L., Teves,M.E., Liu,H.,
            Strauss,J.F. 3rd, Pazour,G.J., Foster,J.A., Hess,R.A. and Zhang,Z.
  TITLE     Intraflagellar transport protein IFT20 is essential for male
            fertility and spermiogenesis in mice
  JOURNAL   Mol Biol Cell 27 (23), 3705-3716 (2016)
   PUBMED   27682589
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   4  (bases 1 to 2306)
  AUTHORS   Wang,X., Wei,Y., Fu,G., Li,H., Saiyin,H., Lin,G., Wang,Z., Chen,S.
            and Yu,L.
  TITLE     Tssk4 is essential for maintaining the structural integrity of
            sperm flagellum
  JOURNAL   Mol Hum Reprod 21 (2), 136-145 (2015)
   PUBMED   25361759
REFERENCE   5  (bases 1 to 2306)
  AUTHORS   Veleri,S., Manjunath,S.H., Fariss,R.N., May-Simera,H., Brooks,M.,
            Foskett,T.A., Gao,C., Longo,T.A., Liu,P., Nagashima,K.,
            Rachel,R.A., Li,T., Dong,L. and Swaroop,A.
  TITLE     Ciliopathy-associated gene Cc2d2a promotes assembly of subdistal
            appendages on the mother centriole during cilia biogenesis
  JOURNAL   Nat Commun 5, 4207 (2014)
   PUBMED   24947469
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 2306)
  AUTHORS   Donkor,F.F., Monnich,M., Czirr,E., Hollemann,T. and Hoyer-Fender,S.
  TITLE     Outer dense fibre protein 2 (ODF2) is a self-interacting
            centrosomal protein with affinity for microtubules
  JOURNAL   J Cell Sci 117 (Pt 20), 4643-4651 (2004)
   PUBMED   15340007
  REMARK    GeneRIF: Data demonstrate that outer dense fibre protein 2 is a
            self-interacting protein that forms a fibrillar structure partially
            linked to the microtubule network.
REFERENCE   7  (bases 1 to 2306)
  AUTHORS   Sun,X.D., Yu,Z.R., Ma,J., Ge,Y.H., Li,S., Xue,S.P. and Han,D.S.
  TITLE     [Characterization of expression of the centrosomal protein,
            Cenexin, in rat spermatogenesis]
  JOURNAL   Shi Yan Sheng Wu Xue Bao 35 (1), 21-25 (2002)
   PUBMED   15344312
  REMARK    GeneRIF: The results suggested that the expression pattern of
            cenexin in rat spermatogenesis might be related to the initiation
            of the flagella formation.
REFERENCE   8  (bases 1 to 2306)
  AUTHORS   Schalles,U., Shao,X., van der Hoorn,F.A. and Oko,R.
  TITLE     Developmental expression of the 84-kDa ODF sperm protein:
            localization to both the cortex and medulla of outer dense fibers
            and to the connecting piece
  JOURNAL   Dev Biol 199 (2), 250-260 (1998)
   PUBMED   9698445
REFERENCE   9  (bases 1 to 2306)
  AUTHORS   Turner,K.J., Sharpe,R.M., Gaughan,J., Millar,M.R., Foster,P.M. and
            Saunders,P.T.
  TITLE     Expression cloning of a rat testicular transcript abundant in germ
            cells, which contains two leucine zipper motifs
  JOURNAL   Biol Reprod 57 (5), 1223-1232 (1997)
   PUBMED   9369191
REFERENCE   10 (bases 1 to 2306)
  AUTHORS   Brohmann,H., Pinnecke,S. and Hoyer-Fender,S.
  TITLE     Identification and characterization of new cDNAs encoding outer
            dense fiber proteins of rat sperm
  JOURNAL   J Biol Chem 272 (15), 10327-10332 (1997)
   PUBMED   9092585
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000003.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26360186.997844.1,
                                           SRR26360172.1832323.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-105               JAXUCZ010000003.1  33559412-33559516
            106-196             JAXUCZ010000003.1  33561832-33561922
            197-350             JAXUCZ010000003.1  33562637-33562790
            351-476             JAXUCZ010000003.1  33563076-33563201
            477-647             JAXUCZ010000003.1  33573346-33573516
            648-808             JAXUCZ010000003.1  33574611-33574771
            809-938             JAXUCZ010000003.1  33575676-33575805
            939-1070            JAXUCZ010000003.1  33576314-33576445
            1071-1142           JAXUCZ010000003.1  33583501-33583572
            1143-1214           JAXUCZ010000003.1  33584898-33584969
            1215-1331           JAXUCZ010000003.1  33585055-33585171
            1332-1517           JAXUCZ010000003.1  33585408-33585593
            1518-1627           JAXUCZ010000003.1  33585910-33586019
            1628-1763           JAXUCZ010000003.1  33588494-33588629
            1764-1874           JAXUCZ010000003.1  33591097-33591207
            1875-1979           JAXUCZ010000003.1  33591328-33591432
            1980-2306           JAXUCZ010000003.1  33592454-33592780
FEATURES             Location/Qualifiers
     source          1..2306
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="3"
                     /map="3p12"
     gene            1..2306
                     /gene="Odf2"
                     /note="outer dense fiber of sperm tails 2"
                     /db_xref="GeneID:29479"
                     /db_xref="RGD:3229"
     exon            1..105
                     /gene="Odf2"
                     /inference="alignment:Splign:2.1.0"
     exon            106..196
                     /gene="Odf2"
                     /inference="alignment:Splign:2.1.0"
     exon            197..350
                     /gene="Odf2"
                     /inference="alignment:Splign:2.1.0"
     CDS             243..2201
                     /gene="Odf2"
                     /note="isoform 5 is encoded by transcript variant 6; outer
                     dense fiber protein 2; testis-specific autoantigen;
                     cenexin; 84 kDa outer dense fiber protein; outer dense
                     fiber of sperm tails protein 2; sperm outer dense fiber
                     major protein 2; outer dense fiber of sperm tail 2"
                     /codon_start=1
                     /product="outer dense fiber protein 2 isoform 5"
                     /protein_id="NP_001386041.1"
                     /db_xref="GeneID:29479"
                     /db_xref="RGD:3229"
                     /translation="MKDRSSTPPLHVHVDENTPVHVHIKKLPKPSAASSQKSHKRGMK
                     GDTVNVRRSVRVKTKVPWMPPGKSSARHVGCKWENPPHCLEITPPSSEKLVSVMRLSD
                     LSTEDDDSGHCKMNRYDKKIDSLMNAVGCLKSEVKMQKGERQMAKRFLEERKEELEEV
                     AHELAETEHENTVLRHNIERIKEEKDFTMLQKKHLQQEKECLMSKLVEAEMDGAAAAK
                     QVMALKDTIGKLKTEKQMTCTDINTLTRQKELLLQKLSTFEETNRTLRDLLREQHCKE
                     DSERLMEQQGALLKRLAEADSEKARLLLLLQDKDKEVEELLQEIQCEKAQAKTASELS
                     KSMESMRGHLQAQLRCKEAENSRLCMQIKNLERSGNQHKAEVEAIMEQLKELKQKGDR
                     DKETLKKAIRAQKERAEKSEEYAEQLHVQLADKDLYVAEALSTLESWRSRYNQVVKDK
                     GDLELEIIVLNDRVTDLVNQQQSLEEKMREDRDSLVERLHRQTAEYSAFKLENERLKA
                     SFAPMEDKLNQAHLEVQQLKASVKNYEGMIDNYKSQVMKTRLEADEVAAQLERCDKEN
                     KMLKDEMNKEIEAARRQFQSQLADLQQLPDILKITEAKLAECQDQLQGYERKNIDLTA
                     IISDLRSRVRDWQKGSHELARAGARLPR"
     exon            351..476
                     /gene="Odf2"
                     /inference="alignment:Splign:2.1.0"
     exon            477..647
                     /gene="Odf2"
                     /inference="alignment:Splign:2.1.0"
     exon            648..808
                     /gene="Odf2"
                     /inference="alignment:Splign:2.1.0"
     exon            809..938
                     /gene="Odf2"
                     /inference="alignment:Splign:2.1.0"
     exon            939..1070
                     /gene="Odf2"
                     /inference="alignment:Splign:2.1.0"
     exon            1071..1142
                     /gene="Odf2"
                     /inference="alignment:Splign:2.1.0"
     exon            1143..1214
                     /gene="Odf2"
                     /inference="alignment:Splign:2.1.0"
     exon            1215..1331
                     /gene="Odf2"
                     /inference="alignment:Splign:2.1.0"
     exon            1332..1517
                     /gene="Odf2"
                     /inference="alignment:Splign:2.1.0"
     exon            1518..1627
                     /gene="Odf2"
                     /inference="alignment:Splign:2.1.0"
     exon            1628..1763
                     /gene="Odf2"
                     /inference="alignment:Splign:2.1.0"
     exon            1764..1874
                     /gene="Odf2"
                     /inference="alignment:Splign:2.1.0"
     exon            1875..1979
                     /gene="Odf2"
                     /inference="alignment:Splign:2.1.0"
     exon            1980..2306
                     /gene="Odf2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gggagccgga ctgcatccgc cgcggcgtct ccatggcacg accctggcct ccgacttcaa
       61 cgacttcata aggagacggt tctgggcgca gccgtgccgc tcttggtttc catcgtgtgg
      121 gaagaacgga gtaacgagtc tcacacagaa aaaagtcttg agaacacctt gtggcgcacc
      181 cagtgtaact gtgacgatcg atcttttttg tgttgccctc ccctgcctgc cagaagtgaa
      241 ccatgaagga ccgatcttca actcccccct tacatgttca tgtggatgag aacactcctg
      301 tccacgtcca cataaaaaaa ctcccgaaac catcagcagc cagcagccag aaatctcata
      361 agcgcggaat gaaaggggac accgtgaatg tacggcggag tgtccgggtg aaaaccaagg
      421 taccttggat gccccctgga aaatcatctg cccggcatgt gggatgcaag tgggagaatc
      481 cacctcattg cctggagatc acaccaccat cttcagaaaa gctggtctcg gtgatgcgat
      541 tgagtgacct ttctacagaa gacgacgatt ctggtcactg taagatgaac cgttacgata
      601 agaagattga cagtctaatg aacgcggtcg gttgtctcaa atctgaggtc aagatgcaga
      661 aaggtgaacg ccaaatggcc aaaaggttcc tggaggagag gaaggaagaa ctggaggagg
      721 tagcacatga gcttgcagag acggagcatg agaacacagt gctcagacac aacatcgagc
      781 gcatcaagga ggagaaggac ttcaccatgc ttcaaaagaa acacctccag caggagaagg
      841 aatgcctcat gtccaaactg gtggaggctg aaatggatgg ggcggctgct gccaaacaag
      901 tcatggcctt gaaggatacc atcgggaagc tgaaaaccga gaaacagatg acttgcaccg
      961 acatcaacac cttaacgagg cagaaggaac ttctcctgca gaagctgagc acctttgaag
     1021 agaccaaccg caccctccga gatctgttga gggagcagca ctgcaaagag gattccgaga
     1081 gactaatgga gcaacaaggt gcattactga aacgtctggc agaggccgac tcagagaaag
     1141 cgcgcctgct gttactactg caagacaagg acaaggaagt ggaagaactc ctccaggaga
     1201 tacaatgtga gaaggctcaa gcaaagacag cgtctgagct ctccaagtcc atggagtcca
     1261 tgcgggggca tttgcaggca cagcttcgct gcaaagaggc tgagaacagc cgcctgtgca
     1321 tgcagatcaa gaatttagag cgcagtggga accagcacaa ggcggaagta gaggccatca
     1381 tggagcagct aaaggaactg aagcaaaagg gagaccgaga caaagagacc ctgaagaagg
     1441 ccatccgagc ccagaaggag cgagctgaga agagtgagga gtatgccgag cagctacatg
     1501 tgcagctggc cgacaaggac ctttatgttg ctgaagcttt atctactctg gagtcatgga
     1561 ggagccgtta caaccaagtt gtgaaagaca aaggagacct tgagttggag atcattgtcc
     1621 taaatgaccg ggtgacagat cttgtaaacc aacaacagag cttggaggag aagatgcggg
     1681 aagaccggga cagcttggta gagagactgc accggcaaac tgctgagtat tctgccttca
     1741 agctagagaa cgagaggctc aaggctagct ttgcccctat ggaggacaag ctcaatcagg
     1801 ctcacttgga ggtccagcaa ctgaaggcat cagtgaagaa ctacgagggg atgatcgaca
     1861 actacaagag ccaggtgatg aaaacaagat tggaggctga cgaagtggct gcgcagctag
     1921 agcgctgcga caaagagaac aagatgctta aagacgagat gaacaaagaa atcgaggcgg
     1981 cccgtcggca gttccagtca cagctggctg acctacaaca gctgcctgac atcctcaaga
     2041 tcacggaggc caagctggct gagtgtcaag accagctgca gggctacgag aggaagaaca
     2101 tcgacctcac agccatcatt tcagacctgc gcagccgggt aagggactgg cagaagggat
     2161 cccacgaact ggcccgagca ggggcccgct taccgagatg agctgcacgc cccccaaggg
     2221 aggaccactt cctttttctt ggctgccgat ttctgaaagg agtgagctat catcagtgct
     2281 gtgaaataaa agtctggtgt gccaaa
//
