LOCUS       NM_001126277            2618 bp    mRNA    linear   ROD 30-JUL-2024
DEFINITION  Rattus norvegicus outer dynein arm docking complex subunit 1
            (Odad1), mRNA.
ACCESSION   NM_001126277 XM_001080782 XM_218574
VERSION     NM_001126277.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2618)
  AUTHORS   Hjeij,R., Onoufriadis,A., Watson,C.M., Slagle,C.E., Klena,N.T.,
            Dougherty,G.W., Kurkowiak,M., Loges,N.T., Diggle,C.P.,
            Morante,N.F., Gabriel,G.C., Lemke,K.L., Li,Y., Pennekamp,P.,
            Menchen,T., Konert,F., Marthin,J.K., Mans,D.A., Letteboer,S.J.,
            Werner,C., Burgoyne,T., Westermann,C., Rutman,A., Carr,I.M.,
            O'Callaghan,C., Moya,E., Chung,E.M., Sheridan,E., Nielsen,K.G.,
            Roepman,R., Bartscherer,K., Burdine,R.D., Lo,C.W., Omran,H. and
            Mitchison,H.M.
  CONSRTM   UK10K Consortium
  TITLE     CCDC151 mutations cause primary ciliary dyskinesia by disruption of
            the outer dynein arm docking complex formation
  JOURNAL   Am J Hum Genet 95 (3), 257-274 (2014)
   PUBMED   25192045
REFERENCE   2  (bases 1 to 2618)
  AUTHORS   Onoufriadis,A., Paff,T., Antony,D., Shoemark,A., Micha,D., Kuyt,B.,
            Schmidts,M., Petridi,S., Dankert-Roelse,J.E., Haarman,E.G.,
            Daniels,J.M., Emes,R.D., Wilson,R., Hogg,C., Scambler,P.J.,
            Chung,E.M., Pals,G. and Mitchison,H.M.
  CONSRTM   UK10K
  TITLE     Splice-site mutations in the axonemal outer dynein arm docking
            complex gene CCDC114 cause primary ciliary dyskinesia
  JOURNAL   Am J Hum Genet 92 (1), 88-98 (2013)
   PUBMED   23261303
REFERENCE   3  (bases 1 to 2618)
  AUTHORS   Knowles,M.R., Leigh,M.W., Ostrowski,L.E., Huang,L., Carson,J.L.,
            Hazucha,M.J., Yin,W., Berg,J.S., Davis,S.D., Dell,S.D.,
            Ferkol,T.W., Rosenfeld,M., Sagel,S.D., Milla,C.E., Olivier,K.N.,
            Turner,E.H., Lewis,A.P., Bamshad,M.J., Nickerson,D.A., Shendure,J.
            and Zariwala,M.A.
  CONSRTM   Genetic Disorders of Mucociliary Clearance Consortium
  TITLE     Exome sequencing identifies mutations in CCDC114 as a cause of
            primary ciliary dyskinesia
  JOURNAL   Am J Hum Genet 92 (1), 99-106 (2013)
   PUBMED   23261302
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC160835.1.
            
            On Aug 31, 2012 this sequence version replaced NM_001126277.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC160835.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760389
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-2618              BC160835.1         3-2620
FEATURES             Location/Qualifiers
     source          1..2618
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q22"
     gene            1..2618
                     /gene="Odad1"
                     /gene_synonym="Ccdc114; RGD1308141"
                     /note="outer dynein arm docking complex subunit 1"
                     /db_xref="GeneID:308594"
                     /db_xref="RGD:1308141"
     exon            1..147
                     /gene="Odad1"
                     /gene_synonym="Ccdc114; RGD1308141"
                     /inference="alignment:Splign:2.1.0"
     exon            148..239
                     /gene="Odad1"
                     /gene_synonym="Ccdc114; RGD1308141"
                     /inference="alignment:Splign:2.1.0"
     CDS             170..2254
                     /gene="Odad1"
                     /gene_synonym="Ccdc114; RGD1308141"
                     /note="coiled-coil domain-containing protein 114;
                     coiled-coil domain containing 114"
                     /codon_start=1
                     /product="outer dynein arm-docking complex subunit 1"
                     /protein_id="NP_001119749.1"
                     /db_xref="GeneID:308594"
                     /db_xref="RGD:1308141"
                     /translation="MRLGLSSRSARSEEGSEIFLEGPVDGELSRLHRQRKVMELERRA
                     YSREVHQRIRKQVEEIRQLEMLRAKLQMQINVAQTQVKRLGDKKRLADMDHLLKCRAQ
                     VQIEIEALQEQNRALEKQIQDWETHILTQSKDISTPDVILDQKMKIQRRIRILEDQLD
                     RVTCHFDIHLVRNAALREELELLRIERGRYLNMDRKLKKEIHLLQEMVGALSTSSTSA
                     YTAREEAKTKMGMLQERAEKELAQSDTEAQILLRQISHLEQLHRFLKLKNHDRQPDPG
                     VVQKEEQRAWETSEGLRKTSQEKLVLRYEDTLNKLAQLTGESDPDLLVEKYLELEERN
                     FAEFNFINEQNSELYHLQEEIKEMQEALVSEHASQDKQSLEREQQCKVLQQDVEKVCS
                     ESERLEARFQVLRVQLEKIKTDIQVLFDKAQCDNSVIKDLLGVKTYMRDRDIGLFLST
                     IEKRLVQLLTVQAFLEVQNNVPLADAALLALGQSIQEPPKKTTPLKPPDTMEDSSGVV
                     IKDDYPMSKEELLSQVMKLVQLQDEEGSPKKRDSSPSLTLSSPRISLAAASVHARKAS
                     VVPESILSHKTGRGRGTGSISHVTFGDSASAPGPVTLASTSASGLPVSGRGSQGGRGA
                     FKHTSSSSYLGSTGYLETSRGRESGTGGGHSQSMGSEMSRGFSSGSGQTSSAAPASRP
                     SSATSKDSRGYN"
     exon            240..339
                     /gene="Odad1"
                     /gene_synonym="Ccdc114; RGD1308141"
                     /inference="alignment:Splign:2.1.0"
     exon            340..529
                     /gene="Odad1"
                     /gene_synonym="Ccdc114; RGD1308141"
                     /inference="alignment:Splign:2.1.0"
     exon            530..652
                     /gene="Odad1"
                     /gene_synonym="Ccdc114; RGD1308141"
                     /inference="alignment:Splign:2.1.0"
     exon            653..766
                     /gene="Odad1"
                     /gene_synonym="Ccdc114; RGD1308141"
                     /inference="alignment:Splign:2.1.0"
     exon            767..834
                     /gene="Odad1"
                     /gene_synonym="Ccdc114; RGD1308141"
                     /inference="alignment:Splign:2.1.0"
     exon            835..1022
                     /gene="Odad1"
                     /gene_synonym="Ccdc114; RGD1308141"
                     /inference="alignment:Splign:2.1.0"
     exon            1023..1157
                     /gene="Odad1"
                     /gene_synonym="Ccdc114; RGD1308141"
                     /inference="alignment:Splign:2.1.0"
     exon            1158..1240
                     /gene="Odad1"
                     /gene_synonym="Ccdc114; RGD1308141"
                     /inference="alignment:Splign:2.1.0"
     exon            1241..1409
                     /gene="Odad1"
                     /gene_synonym="Ccdc114; RGD1308141"
                     /inference="alignment:Splign:2.1.0"
     exon            1410..1573
                     /gene="Odad1"
                     /gene_synonym="Ccdc114; RGD1308141"
                     /inference="alignment:Splign:2.1.0"
     exon            1574..1671
                     /gene="Odad1"
                     /gene_synonym="Ccdc114; RGD1308141"
                     /inference="alignment:Splign:2.1.0"
     exon            1672..1750
                     /gene="Odad1"
                     /gene_synonym="Ccdc114; RGD1308141"
                     /inference="alignment:Splign:2.1.0"
     exon            1751..2590
                     /gene="Odad1"
                     /gene_synonym="Ccdc114; RGD1308141"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tgcaaaggct ggtcaggcac ttgagccggt agagccgaga cctggtcccc accccatccc
       61 aatccggccg gggttcagag gtgcggagag gcggcccagg gaccgagtca gagtcaagcc
      121 gcaggaccca gattgtgtgt gtttggggga cgccaccact acatccaaga tgcgtttggg
      181 tctgtcctcc aggagcgccc gctccgaaga aggaagcgag atcttcctgg agggaccagt
      241 ggatggagaa ctcagccgcc tgcaccgaca acgcaaggtg atggagttgg aaaggcgggc
      301 atacagcagg gaagttcacc agcgcatcag gaagcaagtc gaggagattc ggcagctgga
      361 gatgcttcga gccaagctcc agatgcagat taacgtagcg cagacccagg tcaagcgact
      421 gggagacaag aagcgtttgg cggacatgga ccatcttctc aagtgccggg cccaggtgca
      481 gatcgaaatc gaggcgttgc aagagcagaa ccgggccctg gaaaaacaga tccaggactg
      541 ggagacccat atcctcacgc agagtaagga tatctcaact cctgatgtca tcttggatca
      601 gaagatgaag atccagagaa ggatcaggat cctagaggac cagttggaca gggtcacctg
      661 tcactttgac atccatctgg tgaggaatgc agccctgcgg gaagagctgg agttgctgcg
      721 catcgagagg ggccgctacc tgaatatgga ccgcaagctg aagaaggaga tccacctact
      781 tcaggagatg gttggagctc tcagcacatc ctctacttct gcttatactg ccagggaaga
      841 ggccaagacc aagatgggca tgctgcagga gcgtgcagag aaggagctgg ctcagagtga
      901 cacagaggca cagatcctac tgcgacagat atcgcatctg gagcagctgc accgattcct
      961 caagctcaag aaccatgacc gacagccgga tcccggtgtg gtgcaaaagg aggaacagcg
     1021 agcatgggag acctcagaag gactcagaaa gacttcccaa gagaagctag tgctgcgtta
     1081 cgaggatact ctgaacaaac tggcccagct gaccggcgag agcgacccgg accttttggt
     1141 ggagaaatac ctggagttgg aggaacgcaa ctttgctgag tttaacttca tcaatgagca
     1201 gaactcggaa ctataccatc ttcaggagga gattaaagag atgcaggaag ccttagtcag
     1261 cgagcatgcc agtcaggata agcagagcct ggagcgagag cagcagtgca aagtgttgca
     1321 gcaggatgtg gaaaaagtgt gctctgagtc ggagcggctg gaggctcgct tccaggttct
     1381 ccgagttcag ctggaaaaga tcaagactga tatccaggtt ctcttcgaca aggctcagtg
     1441 tgacaacagt gtcatcaagg atctccttgg ggtcaagacc tacatgcggg atagggacat
     1501 aggtctcttc ctgagtacca ttgagaagcg gctggtgcag cttctcacgg tgcaggcctt
     1561 ccttgaggtc cagaacaatg tccctttggc tgatgctgcg cttctggcac tgggtcagag
     1621 catacaggaa cccccaaaga agactacccc actcaagcct cctgacacca tggaggactc
     1681 ctcaggggtt gtaatcaaag acgattaccc tatgagcaag gaggaactgc tgagtcaagt
     1741 catgaagttg gtgcagctcc aggatgagga ggggtctcca aagaagcggg acagcagccc
     1801 aagtttgact ctttccagcc cacgcatctc cttagcagct gcctctgtgc acgctagaaa
     1861 ggccagcgta gtccctgagt ctatcctgag ccacaagaca ggccgaggcc gtggcactgg
     1921 ctccataagc catgtcacct ttggtgactc tgcttctgct ccaggccctg tgaccttggc
     1981 ttccaccagt gccagtggac tacctgtgtc cggccggggc tctcaggggg ggcgtggggc
     2041 cttcaaacac actagctcca gcagctacct ggggtctact gggtatctag agaccagcag
     2101 aggccgcgag agcgggacag gaggcggtca cagccaaagc atgggatccg agatgagtag
     2161 aggcttcagc tccggcagtg gccagacatc cagtgctgcc cccgcctcca ggcccagctc
     2221 tgctaccagc aaggactcga ggggctataa ctagggttgc aggtcccctt ctgtctcaac
     2281 ccttggcagg ttttctaatt tgtgccctgc tcttccccag agactccttt ccaatccctg
     2341 taagcccagg cctcttgagc ttccctccgt ctcttcccat ctgctcccat cgttaccctg
     2401 ccttggcctt gactctctgt tgccctcctc ctcctccttg cttcccgtct ctgccctcct
     2461 caacctctcc ccgaagcttc ccttcatctg atgtctctgt ctcctaactg gatttccctc
     2521 cattgactta ggtgaaccgt gacaatagga aataaaggtc agagccccgt ttttccaagc
     2581 ccggctccta aaaaaaaaaa aaaaaaaaaa aaaaaaaa
//
