LOCUS       NM_138903                761 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus odorant binding protein I f (Obp1f), mRNA.
ACCESSION   NM_138903
VERSION     NM_138903.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 761)
  AUTHORS   Borysik,A.J., Briand,L., Taylor,A.J. and Scott,D.J.
  TITLE     Rapid odorant release in mammalian odour binding proteins
            facilitates their temporal coupling to odorant signals
  JOURNAL   J Mol Biol 404 (3), 372-380 (2010)
   PUBMED   20932975
  REMARK    GeneRIF: measured the effect of odorant-binding protein 1 on the
            rates of ligand uptake and liquid-to-air transfer rates with a set
            of defined odorous compounds
REFERENCE   2  (bases 1 to 761)
  AUTHORS   Badonnel,K., Durieux,D., Monnerie,R., Grebert,D., Salesse,R.,
            Caillol,M. and Baly,C.
  TITLE     Leptin-sensitive OBP-expressing mucous cells in rat olfactory
            epithelium: a novel target for olfaction-nutrition crosstalk?
  JOURNAL   Cell Tissue Res 338 (1), 53-66 (2009)
   PUBMED   19688223
  REMARK    GeneRIF: Results identify a novel population of odorant-binding
            protein-1f-secreting cells displaying morphological and functional
            characteristics similar to those of epithelial mucous cells.
REFERENCE   3  (bases 1 to 761)
  AUTHORS   White,S.A., Briand,L., Scott,D.J. and Borysik,A.J.
  TITLE     Structure of rat odorant-binding protein OBP1 at 1.6 A resolution
  JOURNAL   Acta Crystallogr D Biol Crystallogr 65 (Pt 5), 403-410 (2009)
   PUBMED   19390145
  REMARK    GeneRIF: Comparisons are made between this 1.6A resolution
            structure and a modelled OBP1 structure based on aphrodisin, and
            with OPB2 and OBP3. It is monomeric.
REFERENCE   4  (bases 1 to 761)
  AUTHORS   Badonnel,K., Denis,J.B., Caillol,M., Monnerie,R., Piumi,F.,
            Potier,M.C., Salesse,R. and Baly,C.
  TITLE     Transcription profile analysis reveals that OBP-1F mRNA is
            downregulated in the olfactory mucosa following food deprivation
  JOURNAL   Chem Senses 32 (7), 697-710 (2007)
   PUBMED   17584948
  REMARK    GeneRIF: The fine transcriptional control of OBP-1F in the
            olfactory mucosa following food deprivation could be efficient only
            at the local level, close to its site of secretion to participate
            in the perireceptor events of the olfactory signal reception.
REFERENCE   5  (bases 1 to 761)
  AUTHORS   Hajjar,E., Perahia,D., Debat,H., Nespoulous,C. and Robert,C.H.
  TITLE     Odorant binding and conformational dynamics in the odorant-binding
            protein
  JOURNAL   J Biol Chem 281 (40), 29929-29937 (2006)
   PUBMED   16849331
  REMARK    GeneRIF: Lipocalin strand pair opening in the presence of ligand is
            observed, consistent with potential role in olfactive receptor
            recognition.
REFERENCE   6  (bases 1 to 761)
  AUTHORS   Nespoulous,C., Briand,L., Delage,M.M., Tran,V. and Pernollet,J.C.
  TITLE     Odorant binding and conformational changes of a rat odorant-binding
            protein
  JOURNAL   Chem Senses 29 (3), 189-198 (2004)
   PUBMED   15047593
  REMARK    GeneRIF: A three-dimensional structure of OBP-1F, modelled using
            the known structure of aphrodisin as template, allowed us to
            suggest the location of the observed structural changes outside of
            the binding pocket.
REFERENCE   7  (bases 1 to 761)
  AUTHORS   Briand,L., Nespoulous,C., Perez,V., Remy,J.J., Huet,J.C. and
            Pernollet,J.C.
  TITLE     Ligand-binding properties and structural characterization of a
            novel rat odorant-binding protein variant
  JOURNAL   Eur J Biochem 267 (10), 3079-3089 (2000)
   PUBMED   10806409
REFERENCE   8  (bases 1 to 761)
  AUTHORS   Pevsner,J., Reed,R.R., Feinstein,P.G. and Snyder,S.H.
  TITLE     Molecular cloning of odorant-binding protein: member of a ligand
            carrier family
  JOURNAL   Science 241 (4863), 336-339 (1988)
   PUBMED   3388043
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000021.1.
            
            On Dec 1, 2020 this sequence version replaced NM_138903.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR22582419.792892.1,
                                           SRR22582416.1325783.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760494
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-97                JAXUCZ010000021.1  45834006-45834102
            98-237              JAXUCZ010000021.1  45834549-45834688
            238-308             JAXUCZ010000021.1  45835117-45835187
            309-419             JAXUCZ010000021.1  45836052-45836162
            420-521             JAXUCZ010000021.1  45837936-45838037
            522-551             JAXUCZ010000021.1  45838218-45838247
            552-761             JAXUCZ010000021.1  45838860-45839069
FEATURES             Location/Qualifiers
     source          1..761
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="X"
                     /map="Xq21"
     gene            1..761
                     /gene="Obp1f"
                     /gene_synonym="Obp-1f"
                     /note="odorant binding protein I f"
                     /db_xref="GeneID:192267"
                     /db_xref="RGD:621639"
     exon            1..97
                     /gene="Obp1f"
                     /gene_synonym="Obp-1f"
                     /inference="alignment:Splign:2.1.0"
     CDS             17..538
                     /gene="Obp1f"
                     /gene_synonym="Obp-1f"
                     /note="OBP; odorant-binding protein 1F"
                     /codon_start=1
                     /product="odorant-binding protein precursor"
                     /protein_id="NP_620258.2"
                     /db_xref="GeneID:192267"
                     /db_xref="RGD:621639"
                     /translation="MVKFLLIVLALGVSCAHHENLDISPSEVNGDWRTLYIVADNVEK
                     VAEGGSLRAYFQHMECGDECQELKIIFNVKLDSECQTHTVVGQKHEDGRYTTDYSGRN
                     YFHVLKKTDDIIFFHNVNVDESGKETNVILVAGKREDLNKAQKQELRKLAEEYNIPNE
                     NTQHLVPTDTCNQ"
     exon            98..237
                     /gene="Obp1f"
                     /gene_synonym="Obp-1f"
                     /inference="alignment:Splign:2.1.0"
     exon            238..308
                     /gene="Obp1f"
                     /gene_synonym="Obp-1f"
                     /inference="alignment:Splign:2.1.0"
     exon            309..419
                     /gene="Obp1f"
                     /gene_synonym="Obp-1f"
                     /inference="alignment:Splign:2.1.0"
     exon            420..521
                     /gene="Obp1f"
                     /gene_synonym="Obp-1f"
                     /inference="alignment:Splign:2.1.0"
     exon            522..551
                     /gene="Obp1f"
                     /gene_synonym="Obp-1f"
                     /inference="alignment:Splign:2.1.0"
     exon            552..761
                     /gene="Obp1f"
                     /gene_synonym="Obp-1f"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gaatccaggc tctaacatgg tgaagtttct gctgattgtt cttgcattag gtgtatcctg
       61 tgcacatcat gaaaatcttg atatcagtcc ctcagaggtt aatggggact ggcgcaccct
      121 ttacatagtt gcagataatg tggagaaggt agcagaaggt ggatccctga gagcttactt
      181 tcagcacatg gaatgtggtg atgaatgcca ggaactcaaa atcatattca atgtcaagtt
      241 ggacagtgaa tgtcagacac acactgttgt gggacaaaaa catgaagatg ggcggtacac
      301 tactgactac tctggtagaa attacttcca tgttttgaag aagacagatg acattatttt
      361 ctttcacaac gttaatgtcg atgagagtgg aaaggagaca aatgtgattt tagttgctgg
      421 gaaacgagag gacctgaaca aagcacagaa acaggagctt aggaagctgg ctgaggaata
      481 taatattcca aacgagaata ctcagcactt ggtgcccaca gacacttgta accaataaag
      541 acaccatatg gcttcacaaa ggacagcaag gtcaacaata tttcccacat caccttttcc
      601 atgaaatcag aatcgtgaca atgaagataa ctcatccttt tcttactttt tcttttcatc
      661 tttcctatga agccagaaaa tctgcttcgt ggatttgttt cccaccctcc tatcatggta
      721 ctgattcttc tgttgatgaa ataaattgat ttttcatgca c
//
