LOCUS       NM_001399137            3412 bp    mRNA    linear   ROD 28-MAR-2024
DEFINITION  Rattus norvegicus O-acyl-ADP-ribose deacylase 1 (Oard1), transcript
            variant 3, mRNA.
ACCESSION   NM_001399137 XM_006244471
VERSION     NM_001399137.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3412)
  AUTHORS   Butepage,M., Preisinger,C., von Kriegsheim,A., Scheufen,A.,
            Lausberg,E., Li,J., Kappes,F., Feederle,R., Ernst,S., Eckei,L.,
            Krieg,S., Muller-Newen,G., Rossetti,G., Feijs,K.L.H., Verheugd,P.
            and Luscher,B.
  TITLE     Nucleolar-nucleoplasmic shuttling of TARG1 and its control by DNA
            damage-induced poly-ADP-ribosylation and by nucleolar transcription
  JOURNAL   Sci Rep 8 (1), 6748 (2018)
   PUBMED   29712969
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3412)
  AUTHORS   Barkauskaite,E., Jankevicius,G. and Ahel,I.
  TITLE     Structures and Mechanisms of Enzymes Employed in the Synthesis and
            Degradation of PARP-Dependent Protein ADP-Ribosylation
  JOURNAL   Mol Cell 58 (6), 935-946 (2015)
   PUBMED   26091342
  REMARK    Review article
REFERENCE   3  (bases 1 to 3412)
  AUTHORS   Sharifi,R., Morra,R., Appel,C.D., Tallis,M., Chioza,B.,
            Jankevicius,G., Simpson,M.A., Matic,I., Ozkan,E., Golia,B.,
            Schellenberg,M.J., Weston,R., Williams,J.G., Rossi,M.N.,
            Galehdari,H., Krahn,J., Wan,A., Trembath,R.C., Crosby,A.H.,
            Ahel,D., Hay,R., Ladurner,A.G., Timinszky,G., Williams,R.S. and
            Ahel,I.
  TITLE     Deficiency of terminal ADP-ribose protein glycohydrolase
            TARG1/C6orf130 in neurodegenerative disease
  JOURNAL   EMBO J 32 (9), 1225-1237 (2013)
   PUBMED   23481255
REFERENCE   4  (bases 1 to 3412)
  AUTHORS   Rosenthal,F., Feijs,K.L., Frugier,E., Bonalli,M., Forst,A.H.,
            Imhof,R., Winkler,H.C., Fischer,D., Caflisch,A., Hassa,P.O.,
            Luscher,B. and Hottiger,M.O.
  TITLE     Macrodomain-containing proteins are new mono-ADP-ribosylhydrolases
  JOURNAL   Nat Struct Mol Biol 20 (4), 502-507 (2013)
   PUBMED   23474714
REFERENCE   5  (bases 1 to 3412)
  AUTHORS   Peterson,F.C., Chen,D., Lytle,B.L., Rossi,M.N., Ahel,I., Denu,J.M.
            and Volkman,B.F.
  TITLE     Orphan macrodomain protein (human C6orf130) is an O-acyl-ADP-ribose
            deacylase: solution structure and catalytic properties
  JOURNAL   J Biol Chem 286 (41), 35955-35965 (2011)
   PUBMED   21849506
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000009.1.
            
            On Jan 4, 2022 this sequence version replaced XM_006244471.3.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26360186.1466896.1,
                                           SRR26643293.48998.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760386 [ECO:0006172]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-158               JAXUCZ010000009.1  20084445-20084602   c
            159-235             JAXUCZ010000009.1  20083894-20083970   c
            236-380             JAXUCZ010000009.1  20083390-20083534   c
            381-439             JAXUCZ010000009.1  20080960-20081018   c
            440-552             JAXUCZ010000009.1  20079898-20080010   c
            553-659             JAXUCZ010000009.1  20078488-20078594   c
            660-3412            JAXUCZ010000009.1  20074507-20077259   c
FEATURES             Location/Qualifiers
     source          1..3412
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="9"
                     /map="9q12"
     gene            1..3412
                     /gene="Oard1"
                     /gene_synonym="RGD1308299"
                     /note="O-acyl-ADP-ribose deacylase 1"
                     /db_xref="GeneID:367214"
                     /db_xref="RGD:1308299"
     exon            1..158
                     /gene="Oard1"
                     /gene_synonym="RGD1308299"
                     /inference="alignment:Splign:2.1.0"
     exon            159..235
                     /gene="Oard1"
                     /gene_synonym="RGD1308299"
                     /inference="alignment:Splign:2.1.0"
     CDS             197..655
                     /gene="Oard1"
                     /gene_synonym="RGD1308299"
                     /note="hypothetical 9.7 kDa protein dJ34B21.3;
                     O-acetyl-ADP-ribose deacetylase 1"
                     /codon_start=1
                     /product="ADP-ribose glycohydrolase OARD1"
                     /protein_id="NP_001386066.1"
                     /db_xref="GeneID:367214"
                     /db_xref="RGD:1308299"
                     /translation="MASRINEDPEGSRITYVKGDLFACPKTDSLAHCISEDCRMGAGI
                     AVLFKKRFGGVQELLSQQKKSGEVAVLKRDGRYIYYLITKKRASHKPTYENLRKSLEA
                     MKSHCLKNGVTDLSMPRIGCGLDRLQWENVSAILEEVFESTDIKITVYTL"
     exon            236..380
                     /gene="Oard1"
                     /gene_synonym="RGD1308299"
                     /inference="alignment:Splign:2.1.0"
     exon            381..439
                     /gene="Oard1"
                     /gene_synonym="RGD1308299"
                     /inference="alignment:Splign:2.1.0"
     exon            440..552
                     /gene="Oard1"
                     /gene_synonym="RGD1308299"
                     /inference="alignment:Splign:2.1.0"
     exon            553..659
                     /gene="Oard1"
                     /gene_synonym="RGD1308299"
                     /inference="alignment:Splign:2.1.0"
     exon            660..3412
                     /gene="Oard1"
                     /gene_synonym="RGD1308299"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 aagggatggg ggcggccatc ttagagtgcg tacaatcaaa ggctttggcg ggatttgttc
       61 tgtgtcgggg cgcttctgtt gcttcccatc ttcgagggtt tcatctcgaa cccttccctg
      121 cgtggaggag ggcctgctga cggccgattc ctttgcagaa gaaactctta aattctggaa
      181 atagcgactc agtatcatgg ccagccgcat taatgaagat ccagaaggaa gtcgaatcac
      241 ttatgtgaaa ggagatcttt tcgcatgccc caaaacagac tctctagccc attgtatcag
      301 tgaggattgt cgaatgggtg ctggaatagc tgttctcttc aagaagagat ttggaggggt
      361 gcaggaactg ttaagtcaac aaaagaagtc tggagaagtg gctgttctga agagagatgg
      421 gcgatatata tattacttga ttacaaagaa acgggcttca cacaagccaa cgtatgagaa
      481 tctacggaag agtttagagg ccatgaagtc ccattgtttg aagaatggcg tcactgacct
      541 ctccatgccc aggattggat gcggtctgga tcgtctgcag tgggaaaatg tatctgcaat
      601 tcttgaagag gtgtttgagt caacagacat caagattacc gtgtacacac tctgaacagg
      661 ggaaagcctg aatccatgaa gcagatgaaa gccgtgatgg gcaggcagat catgatagtc
      721 actcggggaa atctttccgt tccttctccc gtggatcgac tctgcagcct ttcgtgttag
      781 atattcctcc accacctcca cttcagctcc tgtggaaaca tctgaacact tggtcacatc
      841 agtagctctc taggctcctt tgcttttaag gggattatgg ttaatagtta atttttgtca
      901 gggagcttga ttggctgtcg gtgacattct ggaccttggc agggatgtga ttaagtgcct
      961 ttgggtcaaa ttccagtgac ttatcgaaca tgaaacctga ggaaaggaga gcggcctgat
     1021 aactggatga acaccacctc ctcagaagcc cagttagtct gcctgacaga cacccaagca
     1081 ccctgacaga cacgaggtgt gctttcactt ctgcgaggac tcagacaaac cctttgggaa
     1141 gtgacccctg ctcccatcct gtcatcgttt ccaagtgctg cttgttggag tctcacggtg
     1201 tgaacattca gctgttactt ttcaccccca ctttagggag aagaaagttg cttattgctt
     1261 ggctgctggg atgtggatgt cataaaattc tgagccttgt gtcccccacc atactcaaag
     1321 gacaggaaaa gccatccttt acatacaatc ccaggagcgc attgtttctt ttttttcagt
     1381 gttcagtaat gctggggatg gaccgagggc cttgcgtagt ccaccttctg gtcaacccag
     1441 acgctctgct gcctcacact tttactttac gtcagtcagt ctcctggttg ccactgtata
     1501 tcaggctggc cagcccacat acctccaggg attctcgagc cttcgtcttg tactcagatt
     1561 cgtgcttcta catcctgctt catgtgcgtt ctggggatct ggagccaggt tctcgtgctt
     1621 gcagcaagag ctgtacaccc taagccattg ccatctctcc agccctcagg tcaggaccat
     1681 ggtgggaagt cagcctggga gagcgttctt cactgtcaag acctggcttc atcttcctaa
     1741 tgccatggct tggttcttag cctacaaaat ccctgcacct aggtatccgc tctctgacca
     1801 tgggaacttc ccaatgtccc actttcttaa aagaacaggc cacaaaaaac gctatttcct
     1861 ttattgatgt tgctattttg tcttttaaaa agccagctca attcaaaaca cttttctaga
     1921 tgtattttga ggtcaaacct tgactatgaa tctctgtctc aggcagcacc cctggagagg
     1981 caacaagacc ctccaccccc aggtacctgc tgcccacatc acacgttttt cttgtcttca
     2041 ttttcctttc ttccaagagc catgttggaa ggcatggctg aatgaatgat ggcctgagat
     2101 gtgttttgag ttctctgagg ggaggtaatg gtaggtatca gatgtccaac tccaagtaga
     2161 atcaggaagc caggcatgtc ccggatgcca tcctggtcat tgctctgagt ggcagcaggc
     2221 agaccttcat ggaaaacagc acgttactga gagccttgct aactcccgac agccaaccct
     2281 cagagataac taaagcctct tttgctttcc ctaaaagacc ctggatgtcc tctccgggac
     2341 cacctgtgct tcccggctga gctggtgttg gggttgtctc ttcactgctg tggtggtgtt
     2401 agcacagccc cagagatctg tttggagtct gctctcttac gttaaacaca caatacaaat
     2461 gctctgctgt agctttgtgt ggtccagaac ttacaacaga ccaggctagc cttgaactca
     2521 gctgtctacc tcagcttccc atgggccagt cagccagtct ttcttaaagc aaaagataaa
     2581 aataagagat agacaaattg tatttctaaa gtgcttgctt tttagtgaac tttaagtagg
     2641 gctggctgtt cttaaggggc atttgtagac tgtcatggct tttttttttt ttttttggat
     2701 tgtatttgac ctgccctcag gaactcagaa gacccacaga tatgccaaag gaagtgtgct
     2761 gatgggttca agaatattgt tgtgccctgg gttcagtcct tagctccaaa acaaaaacaa
     2821 aaacaaaaaa atgttgtatc tgtataccca agaaggagtt aaattctttt taacattaca
     2881 cttatttatg tgtacagggg gcggcatgta ggtttggagg ttgaagaata actttgggga
     2941 ttagtcctct ctttccacta tgtgggtccc atagatgaaa ctcgggtctt caggattggt
     3001 ggtgagcacc tttactaggt gacccgctgg cccaaaatat tctattttaa aataagctga
     3061 cttagacacg tacttctccc tcgtaccgga ttatttactg agtgtcaaaa cccccagtga
     3121 tccaaatcta aaactttaat tatcattgaa attcacaatt ttaattaaag taaaaaagat
     3181 ccctgaagac ttgctagttt ggtagctggc agaagtgggc tgtaaaagtc ttcaaagggg
     3241 ctggagagtt agctcagtcg gttaaggagc aaagctggac acctgagctc cattcccggg
     3301 gctcacacag tggaaacaca gccccagctc tggtaagttg tcctctgacc tccgtgtgtg
     3361 ccttgacatg tgccccttcc acatacacat aaataaatgt aatctcatta aa
//
