LOCUS       NM_001170429             891 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus nucleoredoxin-like 2 (Nxnl2), mRNA.
ACCESSION   NM_001170429 XM_001054275 XM_001070068
VERSION     NM_001170429.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 891)
  AUTHORS   Wolloscheck,T., Kunst,S., Kelleher,D.K. and Spessert,R.
  TITLE     Transcriptional regulation of nucleoredoxin-like genes takes place
            on a daily basis in the retina and pineal gland of rats
  JOURNAL   Vis Neurosci 32, E002 (2015)
   PUBMED   26239254
  REMARK    GeneRIF: This study demonstrated that the Nxnl2 were seen to
            display daily rhythms with steadily increasing values during the
            light phase and peak expression around dark onset in preparations
            of whole retina.
REFERENCE   2  (bases 1 to 891)
  AUTHORS   Jaillard,C., Mouret,A., Niepon,M.L., Clerin,E., Yang,Y.,
            Lee-Rivera,I., Ait-Ali,N., Millet-Puel,G., Cronin,T., Sedmak,T.,
            Raffelsberger,W., Kinzel,B., Trembleau,A., Poch,O., Bennett,J.,
            Wolfrum,U., Lledo,P.M., Sahel,J.A. and Leveillard,T.
  TITLE     Nxnl2 splicing results in dual functions in neuronal cell survival
            and maintenance of cell integrity
  JOURNAL   Hum Mol Genet 21 (10), 2298-2311 (2012)
   PUBMED   22343139
REFERENCE   3  (bases 1 to 891)
  AUTHORS   Chalmel,F., Leveillard,T., Jaillard,C., Lardenois,A., Berdugo,N.,
            Morel,E., Koehl,P., Lambrou,G., Holmgren,A., Sahel,J.A. and Poch,O.
  TITLE     Rod-derived Cone Viability Factor-2 is a novel
            bifunctional-thioredoxin-like protein with therapeutic potential
  JOURNAL   BMC Mol Biol 8, 74 (2007)
   PUBMED   17764561
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000017.1.
            
            On or before Dec 19, 2009 this sequence version replaced
            XM_001070068.1, XM_001054275.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR22582416.820066.1,
                                           SRR22582416.1467649.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760433, SAMEA5760434
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-302               JAXUCZ010000017.1  14187294-14187595   c
            303-891             JAXUCZ010000017.1  14182849-14183437   c
FEATURES             Location/Qualifiers
     source          1..891
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="17"
                     /map="17p14"
     gene            1..891
                     /gene="Nxnl2"
                     /gene_synonym="Rdcvf2"
                     /note="nucleoredoxin-like 2"
                     /db_xref="GeneID:689232"
                     /db_xref="RGD:1594820"
     CDS             1..471
                     /gene="Nxnl2"
                     /gene_synonym="Rdcvf2"
                     /EC_number="1.8.1.8"
                     /codon_start=1
                     /product="nucleoredoxin-like protein 2"
                     /protein_id="NP_001163900.1"
                     /db_xref="GeneID:689232"
                     /db_xref="RGD:1594820"
                     /translation="MVDVLGGRRLMTREGTLVEAEAALQNKVVALYFAAGRCAPSRDF
                     TPLLCDFYTELVSEARRPAPFEVVFVSADRSAEEMLDFMRELHGSWLALPFHDPYRHE
                     LKKRYDITVIPKVVVIKQNGAVITNKGRKQIRERGLACFQNWVEAADVFQNFSG"
     exon            1..302
                     /gene="Nxnl2"
                     /gene_synonym="Rdcvf2"
                     /inference="alignment:Splign:2.1.0"
     exon            303..891
                     /gene="Nxnl2"
                     /gene_synonym="Rdcvf2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atggtggacg tgctgggcgg gcggcgcctg atgacccgcg agggcacgct ggtggaggcc
       61 gaggcggcgc tgcagaacaa ggtggtagct ctgtactttg ccgcaggccg gtgcgcgccc
      121 agccgcgact tcacgccgct gctctgcgac ttctacacgg agctggtgag cgaggcgcgg
      181 cggcccgcac ccttcgaggt ggttttcgtg tcggcggacc gcagcgccga agagatgctg
      241 gacttcatgc gcgagctgca cggctcctgg ctggcattgc ccttccacga cccctaccgg
      301 catgagctga agaagaggta tgacatcacc gtcatcccca aggtcgtggt catcaagcag
      361 aatggagccg tcatcaccaa caaagggcgg aaacagatcc gggagcgcgg actagcttgc
      421 tttcagaact gggtggaagc agctgatgtt ttccaaaact tctcagggtg aatctgcagg
      481 gatcagagta ggtgctggaa gtgcagggcg acctgccttc aaggagggct taactggttc
      541 tcttctctgt ttggggatgt catagccgag tcaccaagct gtggcagaga gcggaaacag
      601 ctcagggaag aactacaccc accctctgtg ggtcctagag ctccttcggg gtgaactttt
      661 attacttata gctttctcca cccgtgccta ggctccagga cacatgggca gtgagctacc
      721 agagacctat gcgagatact ctttcctgca ggtttctctg gaaaattgac ctatgaggtg
      781 atgtgttttc tgacgaccta tcacacttta gtgatgcttt ggtaaacatc tctgttactc
      841 aagtttgtcc actgtgtaat ttaataaacc aacattcaca gtttgagcag a
//
