LOCUS       NM_021579               2234 bp    mRNA    linear   ROD 27-MAR-2024
DEFINITION  Rattus norvegicus nuclear RNA export factor 1 (Nxf1), mRNA.
ACCESSION   NM_021579 XM_346573
VERSION     NM_021579.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2234)
  AUTHORS   Roundtree,I.A., Luo,G.Z., Zhang,Z., Wang,X., Zhou,T., Cui,Y.,
            Sha,J., Huang,X., Guerrero,L., Xie,P., He,E., Shen,B. and He,C.
  TITLE     YTHDC1 mediates nuclear export of N6-methyladenosine methylated
            mRNAs
  JOURNAL   Elife 6, e31311 (2017)
   PUBMED   28984244
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2234)
  AUTHORS   Viphakone,N., Cumberbatch,M.G., Livingstone,M.J., Heath,P.R.,
            Dickman,M.J., Catto,J.W. and Wilson,S.A.
  TITLE     Luzp4 defines a new mRNA export pathway in cancer cells
  JOURNAL   Nucleic Acids Res 43 (4), 2353-2366 (2015)
   PUBMED   25662211
REFERENCE   3  (bases 1 to 2234)
  AUTHORS   Natalizio,B.J. and Wente,S.R.
  TITLE     Postage for the messenger: designating routes for nuclear mRNA
            export
  JOURNAL   Trends Cell Biol 23 (8), 365-373 (2013)
   PUBMED   23583578
  REMARK    Review article
REFERENCE   4  (bases 1 to 2234)
  AUTHORS   Teng,I.F. and Wilson,S.A.
  TITLE     Mapping interactions between mRNA export factors in living cells
  JOURNAL   PLoS One 8 (6), e67676 (2013)
   PUBMED   23826332
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 2234)
  AUTHORS   Chang,C.T., Hautbergue,G.M., Walsh,M.J., Viphakone,N., van
            Dijk,T.B., Philipsen,S. and Wilson,S.A.
  TITLE     Chtop is a component of the dynamic TREX mRNA export complex
  JOURNAL   EMBO J 32 (3), 473-486 (2013)
   PUBMED   23299939
REFERENCE   6  (bases 1 to 2234)
  AUTHORS   Sasaki,M., Takeda,E., Takano,K., Yomogida,K., Katahira,J. and
            Yoneda,Y.
  TITLE     Molecular cloning and functional characterization of mouse Nxf
            family gene products
  JOURNAL   Genomics 85 (5), 641-653 (2005)
   PUBMED   15820316
REFERENCE   7  (bases 1 to 2234)
  AUTHORS   Irwin,S., Vandelft,M., Pinchev,D., Howell,J.L., Graczyk,J.,
            Orr,H.T. and Truant,R.
  TITLE     RNA association and nucleocytoplasmic shuttling by ataxin-1
  JOURNAL   J Cell Sci 118 (Pt 1), 233-242 (2005)
   PUBMED   15615787
REFERENCE   8  (bases 1 to 2234)
  AUTHORS   Saito,K., Fujiwara,T., Katahira,J., Inoue,K. and Sakamoto,H.
  TITLE     TAP/NXF1, the primary mRNA export receptor, specifically interacts
            with a neuronal RNA-binding protein HuD
  JOURNAL   Biochem Biophys Res Commun 321 (2), 291-297 (2004)
   PUBMED   15358174
REFERENCE   9  (bases 1 to 2234)
  AUTHORS   Monshausen,M., Gehring,N.H. and Kosik,K.S.
  TITLE     The mammalian RNA-binding protein Staufen2 links nuclear and
            cytoplasmic RNA processing pathways in neurons
  JOURNAL   Neuromolecular Med 6 (2-3), 127-144 (2004)
   PUBMED   15970630
REFERENCE   10 (bases 1 to 2234)
  AUTHORS   Levesque,L., Guzik,B., Guan,T., Coyle,J., Black,B.E., Rekosh,D.,
            Hammarskjold,M.L. and Paschal,B.M.
  TITLE     RNA export mediated by tap involves NXT1-dependent interactions
            with the nuclear pore complex
  JOURNAL   J Biol Chem 276 (48), 44953-44962 (2001)
   PUBMED   11579093
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000001.1.
            
            On Nov 27, 2020 this sequence version replaced NM_021579.1.
            
            Sequence Note: This sequence has been modified as follows: removed
            52 bp suspected to be vector contamination from the 5' end.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AF093139.2, SRR26360176.1351018.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-96                JAXUCZ010000001.1  215084563-215084658
            97-280              JAXUCZ010000001.1  215089232-215089415
            281-434             JAXUCZ010000001.1  215089610-215089763
            435-518             JAXUCZ010000001.1  215090456-215090539
            519-623             JAXUCZ010000001.1  215090620-215090724
            624-704             JAXUCZ010000001.1  215090844-215090924
            705-774             JAXUCZ010000001.1  215091005-215091074
            775-863             JAXUCZ010000001.1  215091186-215091274
            864-971             JAXUCZ010000001.1  215091381-215091488
            972-1081            JAXUCZ010000001.1  215091826-215091935
            1082-1118           JAXUCZ010000001.1  215093698-215093734
            1119-1187           JAXUCZ010000001.1  215093977-215094045
            1188-1243           JAXUCZ010000001.1  215094125-215094180
            1244-1351           JAXUCZ010000001.1  215094298-215094405
            1352-1410           JAXUCZ010000001.1  215094505-215094563
            1411-1526           JAXUCZ010000001.1  215094658-215094773
            1527-1569           JAXUCZ010000001.1  215094898-215094940
            1570-1642           JAXUCZ010000001.1  215095693-215095765
            1643-1825           JAXUCZ010000001.1  215096036-215096218
            1826-1886           JAXUCZ010000001.1  215097113-215097173
            1887-2234           JAXUCZ010000001.1  215097409-215097756
FEATURES             Location/Qualifiers
     source          1..2234
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q43"
     gene            1..2234
                     /gene="Nxf1"
                     /gene_synonym="Mex67h; Tap"
                     /note="nuclear RNA export factor 1"
                     /db_xref="GeneID:59087"
                     /db_xref="RGD:62014"
     exon            1..96
                     /gene="Nxf1"
                     /gene_synonym="Mex67h; Tap"
                     /inference="alignment:Splign:2.1.0"
     CDS             69..1925
                     /gene="Nxf1"
                     /gene_synonym="Mex67h; Tap"
                     /note="mRNA export factor TAP; tip-associated protein;
                     tip-associating protein; nuclear RNA export factor 1
                     homolog"
                     /codon_start=1
                     /product="nuclear RNA export factor 1"
                     /protein_id="NP_067590.2"
                     /db_xref="GeneID:59087"
                     /db_xref="RGD:62014"
                     /translation="MADEGKSYNEHDDRVSFPQRRKKGRGPFRWKCGEGNRRSGRGGS
                     GIRSSRFEEDDGDVAMNDPQDGPRVRYNPYTSRPNRRRDTWHDRDRIHVTVRRDRAPQ
                     ERGGAGTSQDGTTKNWFKITIPYGKKYDKMWLLSMIQSKCSVPFNPIEFHYENTRAQF
                     FVEDATTASALKAVNYKIQDRENRRISIIINSSAPPYIVQNELKPEQVEQLKLIMSKR
                     YDGSQQALDLKGLRSDPDLVAQNIDVVLNRRGCMAAALRIIEENIPELLSLNLSNNRL
                     YKLDDMSSIVQKAPNLKILNLSGNELKSEWELDKIKGLKLEELWLDRNPMCDTFLDQS
                     TYISTIRERFPKLLRLDGHELPPPIAFDVEAPTMLPPCKGSYFGTENLKSLVLHFLQQ
                     YYAIYDSGDRQGLLDAYHDGACCSLSTPSNPQNPVRHNLAKYFNDSRNVKKIKDTTTR
                     FRLLKHTRLNVVAFLNELPKTHHDVNSFVVDISAQTSTLLCFSVNGVFKEVDGKSRDS
                     LRAFTRTFIAVPASNSGLCIVNDELFVRNASPEEIQRAFAMPAPTPSSSPVPTLSQEQ
                     QDMLQAFSTQSGMNLEWSQKCLQDNNWDYTRSAQAFTHLKAKGEIPEVAFMK"
     exon            97..280
                     /gene="Nxf1"
                     /gene_synonym="Mex67h; Tap"
                     /inference="alignment:Splign:2.1.0"
     exon            281..434
                     /gene="Nxf1"
                     /gene_synonym="Mex67h; Tap"
                     /inference="alignment:Splign:2.1.0"
     exon            435..518
                     /gene="Nxf1"
                     /gene_synonym="Mex67h; Tap"
                     /inference="alignment:Splign:2.1.0"
     exon            519..623
                     /gene="Nxf1"
                     /gene_synonym="Mex67h; Tap"
                     /inference="alignment:Splign:2.1.0"
     exon            624..704
                     /gene="Nxf1"
                     /gene_synonym="Mex67h; Tap"
                     /inference="alignment:Splign:2.1.0"
     exon            705..774
                     /gene="Nxf1"
                     /gene_synonym="Mex67h; Tap"
                     /inference="alignment:Splign:2.1.0"
     exon            775..863
                     /gene="Nxf1"
                     /gene_synonym="Mex67h; Tap"
                     /inference="alignment:Splign:2.1.0"
     exon            864..971
                     /gene="Nxf1"
                     /gene_synonym="Mex67h; Tap"
                     /inference="alignment:Splign:2.1.0"
     exon            972..1081
                     /gene="Nxf1"
                     /gene_synonym="Mex67h; Tap"
                     /inference="alignment:Splign:2.1.0"
     exon            1082..1118
                     /gene="Nxf1"
                     /gene_synonym="Mex67h; Tap"
                     /inference="alignment:Splign:2.1.0"
     exon            1119..1187
                     /gene="Nxf1"
                     /gene_synonym="Mex67h; Tap"
                     /inference="alignment:Splign:2.1.0"
     exon            1188..1243
                     /gene="Nxf1"
                     /gene_synonym="Mex67h; Tap"
                     /inference="alignment:Splign:2.1.0"
     exon            1244..1351
                     /gene="Nxf1"
                     /gene_synonym="Mex67h; Tap"
                     /inference="alignment:Splign:2.1.0"
     exon            1352..1410
                     /gene="Nxf1"
                     /gene_synonym="Mex67h; Tap"
                     /inference="alignment:Splign:2.1.0"
     exon            1411..1526
                     /gene="Nxf1"
                     /gene_synonym="Mex67h; Tap"
                     /inference="alignment:Splign:2.1.0"
     exon            1527..1569
                     /gene="Nxf1"
                     /gene_synonym="Mex67h; Tap"
                     /inference="alignment:Splign:2.1.0"
     exon            1570..1642
                     /gene="Nxf1"
                     /gene_synonym="Mex67h; Tap"
                     /inference="alignment:Splign:2.1.0"
     exon            1643..1825
                     /gene="Nxf1"
                     /gene_synonym="Mex67h; Tap"
                     /inference="alignment:Splign:2.1.0"
     exon            1826..1886
                     /gene="Nxf1"
                     /gene_synonym="Mex67h; Tap"
                     /inference="alignment:Splign:2.1.0"
     exon            1887..2234
                     /gene="Nxf1"
                     /gene_synonym="Mex67h; Tap"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ccaaggcgtc cgggtgtttg gtggcgtcag gttctgcgcc tgagcccgcc cctgtacctg
       61 cctgtgccat ggcggacgaa gggaagtcat acaacgaaca tgatgaccgt gttagtttcc
      121 cacaaagaag aaagaaaggt cgggggcctt tccgatggaa gtgtggtgag gggaatcgta
      181 ggtctggaag aggtggttct ggtatacggt cttcccggtt tgaggaagat gatggagatg
      241 tggcaatgaa tgatccccag gatggccccc gagtgagata caacccctat accagccgac
      301 ctaaccgtcg gagagatact tggcatgatc gagatcggat tcatgttact gtacggagag
      361 acagagctcc tcaagaaaga ggaggtgctg gcaccagtca agatgggacc accaagaact
      421 ggttcaagat tacaattcct tatggcaaaa agtatgataa aatgtggctt ctgagcatga
      481 ttcagagcaa gtgcagtgtc cccttcaacc ccattgagtt tcactatgaa aatacacggg
      541 cccagttttt tgtggaagat gccactaccg cttctgcatt aaaggctgtc aactataaga
      601 ttcaggatcg agaaaacaga aggatatcta tcatcatcaa ctcttctgct ccaccctata
      661 ttgtacagaa tgaactgaag cctgaacaag tagagcagct caagctgatc atgagcaaac
      721 gatatgatgg ctcccagcaa gcacttgacc tcaagggcct ccgctcagac ccagatttgg
      781 tggcccagaa catcgatgtt gttctaaacc gtagaggctg tatggcagcc gccctgagga
      841 tcattgaaga gaacattcct gagctattgt ctttgaactt gagtaacaac aggctgtaca
      901 agcttgatga catgtccagc attgtacaga aggcaccaaa cttaaagatc ctgaatctct
      961 ctggaaacga attgaagtcc gagtgggaat tagacaagat aaaagggctg aagctggaag
     1021 agctgtggct tgacagaaac cccatgtgtg acaccttcct agaccagtcc acctatatca
     1081 gcaccattcg cgaacgattt cccaagttat tacgcctgga tggccatgag ctaccccctc
     1141 caattgcctt tgatgtcgaa gcccctacta tgttaccacc ctgcaaggga agctattttg
     1201 gaacagagaa cctaaagagt ctggtcctgc acttcttgca gcagtactat gcaatttatg
     1261 actcaggaga ccgccagggt cttctggatg cctaccatga tggcgcctgt tgctcgctaa
     1321 gcactccttc caaccctcag aaccctgtcc gacacaactt agccaaatac ttcaatgaca
     1381 gcagaaatgt gaagaagatt aaagatacca ccacgcggtt ccggctatta aagcatacac
     1441 gtcttaatgt cgttgccttc ctcaatgagt tacctaaaac tcaccatgac gttaactcct
     1501 ttgtggtaga tataagtgcc caaacaagca cattgttgtg tttttctgtc aatggagtct
     1561 tcaaggaagt ggacgggaag tctcgagatt ctttacgtgc tttcacgaga acgttcattg
     1621 ctgttcctgc cagcaattca gggctatgta ttgtaaatga cgaattattt gtgcggaacg
     1681 ccagccctga agaaatccaa agagccttcg ccatgcctgc acccacacct tcttccagcc
     1741 cagtacccac actctcccaa gaacagcagg atatgttaca agcattttct acccagtctg
     1801 gcatgaacct cgagtggtct cagaagtgcc ttcaagacaa taactgggac tacaccagat
     1861 ctgcccaggc cttcactcat ctcaaggcca agggagagat tccagaagta gcgtttatga
     1921 aatgatctca agaaaagtcc ccttgtaaat agcccttgga taatattgtc tggctgtcat
     1981 ctgcggactc ctgtccagcc cgaggccacc ctgtaactgt gactggggag gaagggctgc
     2041 ttcatcctcc tcacctacct tctggaagac ttagagaaga cttccggaag attgagcctc
     2101 atggtgccag gaagccaaag cttactttgt agagctgaca ctaaattacc gaaggactta
     2161 ggtgctctgt gtacttaacc ccaggattcc ctttactttt taagataaag agtgatattg
     2221 tagtgtgtgt ccca
//
