LOCUS       NM_001007629            1930 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus nuclear transport factor 2 (Nutf2), mRNA.
ACCESSION   NM_001007629 XM_214670
VERSION     NM_001007629.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1930)
  AUTHORS   Buschow,S.I., van Balkom,B.W., Aalberts,M., Heck,A.J., Wauben,M.
            and Stoorvogel,W.
  TITLE     MHC class II-associated proteins in B-cell exosomes and potential
            functional implications for exosome biogenesis
  JOURNAL   Immunol Cell Biol 88 (8), 851-856 (2010)
   PUBMED   20458337
REFERENCE   2  (bases 1 to 1930)
  AUTHORS   Jovanovic-Talisman,T., Tetenbaum-Novatt,J., McKenney,A.S.,
            Zilman,A., Peters,R., Rout,M.P. and Chait,B.T.
  TITLE     Artificial nanopores that mimic the transport selectivity of the
            nuclear pore complex
  JOURNAL   Nature 457 (7232), 1023-1027 (2009)
   PUBMED   19098896
REFERENCE   3  (bases 1 to 1930)
  AUTHORS   Li,B., Zhang,H.Q., Shi,Y., Min,Y.B., Lin,S.F., Wu,K.L., Hu,J. and
            Tang,S.B.
  TITLE     Overexpression of nuclear transport factor 2 may protect against
            diabetic retinopathy
  JOURNAL   Mol Vis 15, 861-869 (2009)
   PUBMED   19404486
  REMARK    GeneRIF: NTF2 is a potential mediator of retinal vasculature
            integrity.
REFERENCE   4  (bases 1 to 1930)
  AUTHORS   Van Impe,K., Hubert,T., De Corte,V., Vanloo,B., Boucherie,C.,
            Vandekerckhove,J. and Gettemans,J.
  TITLE     A new role for nuclear transport factor 2 and Ran: nuclear import
            of CapG
  JOURNAL   Traffic 9 (5), 695-707 (2008)
   PUBMED   18266911
REFERENCE   5  (bases 1 to 1930)
  AUTHORS   Kurisaki,A., Kurisaki,K., Kowanetz,M., Sugino,H., Yoneda,Y.,
            Heldin,C.H. and Moustakas,A.
  TITLE     The mechanism of nuclear export of Smad3 involves exportin 4 and
            Ran
  JOURNAL   Mol Cell Biol 26 (4), 1318-1332 (2006)
   PUBMED   16449645
REFERENCE   6  (bases 1 to 1930)
  AUTHORS   Clarkson,W.D., Kent,H.M. and Stewart,M.
  TITLE     Separate binding sites on nuclear transport factor 2 (NTF2) for
            GDP-Ran and the phenylalanine-rich repeat regions of nucleoporins
            p62 and Nsp1p
  JOURNAL   J Mol Biol 263 (4), 517-524 (1996)
   PUBMED   8918934
REFERENCE   7  (bases 1 to 1930)
  AUTHORS   Hu,T., Guan,T. and Gerace,L.
  TITLE     Molecular and functional characterization of the p62 complex, an
            assembly of nuclear pore complex glycoproteins
  JOURNAL   J Cell Biol 134 (3), 589-601 (1996)
   PUBMED   8707840
REFERENCE   8  (bases 1 to 1930)
  AUTHORS   Bullock,T.L., Clarkson,W.D., Kent,H.M. and Stewart,M.
  TITLE     The 1.6 angstroms resolution crystal structure of nuclear transport
            factor 2 (NTF2)
  JOURNAL   J Mol Biol 260 (3), 422-431 (1996)
   PUBMED   8757804
REFERENCE   9  (bases 1 to 1930)
  AUTHORS   Kent,H.M., Clarkson,W.D., Bullock,T.L. and Stewart,M.
  TITLE     Crystallization and preliminary X-ray diffraction analysis of
            nuclear transport factor 2
  JOURNAL   J Struct Biol 116 (2), 326-329 (1996)
   PUBMED   8812990
REFERENCE   10 (bases 1 to 1930)
  AUTHORS   Paschal,B.M. and Gerace,L.
  TITLE     Identification of NTF2, a cytosolic factor for nuclear import that
            interacts with nuclear pore complex protein p62
  JOURNAL   J Cell Biol 129 (4), 925-937 (1995)
   PUBMED   7744965
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000019.1.
            
            On Nov 27, 2020 this sequence version replaced NM_001007629.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC061569.1, CB577395.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-33                JAXUCZ010000019.1  50662181-50662213
            34-160              JAXUCZ010000019.1  50676616-50676742
            161-232             JAXUCZ010000019.1  50678882-50678953
            233-331             JAXUCZ010000019.1  50679038-50679136
            332-1930            JAXUCZ010000019.1  50681859-50683457
FEATURES             Location/Qualifiers
     source          1..1930
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="19"
                     /map="19q12"
     gene            1..1930
                     /gene="Nutf2"
                     /gene_synonym="NTF2"
                     /note="nuclear transport factor 2"
                     /db_xref="GeneID:291981"
                     /db_xref="RGD:1359213"
     exon            1..33
                     /gene="Nutf2"
                     /gene_synonym="NTF2"
                     /inference="alignment:Splign:2.1.0"
     exon            34..160
                     /gene="Nutf2"
                     /gene_synonym="NTF2"
                     /inference="alignment:Splign:2.1.0"
     CDS             62..445
                     /gene="Nutf2"
                     /gene_synonym="NTF2"
                     /note="NTF-2"
                     /codon_start=1
                     /product="nuclear transport factor 2"
                     /protein_id="NP_001007630.1"
                     /db_xref="GeneID:291981"
                     /db_xref="RGD:1359213"
                     /translation="MGDKPIWEQIGSSFIQHYYQLFDNDRTQLGAIYIDASCLTWEGQ
                     QFQGKAAIVEKLSSLPFQKIQHSITAQDHQPTPDSCIISMVVGQLKADEDPIMGFHQM
                     FLLKNINDAWVCTNDMFRLALHNFG"
     exon            161..232
                     /gene="Nutf2"
                     /gene_synonym="NTF2"
                     /inference="alignment:Splign:2.1.0"
     exon            233..331
                     /gene="Nutf2"
                     /gene_synonym="NTF2"
                     /inference="alignment:Splign:2.1.0"
     exon            332..1930
                     /gene="Nutf2"
                     /gene_synonym="NTF2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gccgccgctg ccgccatcgt gccagcccca cgggtctcag tgaggtgggt gactctccag
       61 gatgggagac aagccaattt gggagcagat tggatccagc tttattcagc attactatca
      121 gttatttgat aacgacagaa cccaactagg cgcaatttac attgatgcgt catgccttac
      181 gtgggaagga cagcaattcc agggcaaagc tgccattgtg gagaagctat ctagccttcc
      241 gttccagaaa attcagcata gtatcacggc gcaggaccat cagcctacac cagatagctg
      301 catcatcagc atggttgtag gccagctcaa ggctgatgaa gatcccatca tgggtttcca
      361 ccagatgttt ctattaaaga acatcaatga cgcttgggtt tgcaccaatg acatgttcag
      421 gcttgccctg cacaacttcg gctgacctcc tcctggccag atagtcacgc tgtttcctcc
      481 tcccttttcc caatcctatc tcctccagat gctccaaata tcatacacaa acgagcaggg
      541 ccgaggtggg agtgggtgca gtgcgcttct gtcaccacgg tattgtgcat gatgtttgga
      601 tgctagacta gttgcatctg acaggaaaag tttgtgttgt accagcgcat gccttggaaa
      661 gacttaagta atgcaaaaga ttgtcggttt ttggttttgt tttctttttt tttttttttt
      721 tttaatctac tgacaagttg ctctagtaac ccaaagaagt gaaggagaaa gcagctgcct
      781 caccaaccgc ccagatatcg atttgttcag atgtttcaat gcctcatgat acaataaaac
      841 cacaaaaatt ttcttaacag tttaaattgt tttaattagt taagtagttg gctgggcatc
      901 agcagctctg gcccattgtc tctgatgcca ccctcccatc tgcctcacct taacagtacc
      961 tgctgcaggg agcaaagtca ctcacatggc agtccaccta agccctcaag tctgctggga
     1021 cagttctctc cagcccaggt ctttggaaag caggtctggc ctgaagcttc tcttgtactg
     1081 aaggctcttc agtcagctct gtctgacacc tccagtggcc tctgctctgt agactcgggt
     1141 ctagtagcag gacagatgat tctgtagcag ctacaaaggc cttggcaaat atgacctccc
     1201 atgtttatac cctctgggtt gaatctcaga tggagaggcc tgctctatac ccacaaaaaa
     1261 tgactttcag atgtctacat tccccaagca aagcaagaga tgctgtactg cctgcttggg
     1321 gtattggagc caggccccat tgcgtggagt ataaattcca cactatggaa acaatcagtg
     1381 tgaaggagtc ttgctctagc tgccccctca agacttgtgc agggcattta cacgccatct
     1441 ccttacttcc cacacacccc atactctcat caaatcccaa gaagtcttaa ctattatggc
     1501 agtttctgcc ctgtttctta gtctgggcac aggtcttgct cagtacaaat aaagcttttc
     1561 gtccttgaga cctctggata gtataaagct accaaaatag caactgcaag ctggaaccaa
     1621 gcccaagatt tggggctgag gattggctag gcacacctga aagctcccac ctccccgcca
     1681 ttctgcacta tgagggggag agtaaataga tttctgcaaa cgctccaggt tgcctggtta
     1741 caccagcata gtcatggaca ccacacaaga gggtccagtg ggattgattt ctaagctgct
     1801 gtgtattggg ggaagtaggg gtgggagagg tagatgccag ctgcctctta ctccaccctg
     1861 tataaaatct gcaatacggc tgcttccatg tacctgtgcc taatgtctgc aataaagagg
     1921 tgtttgtaaa
//
