LOCUS       NM_053616               2412 bp    mRNA    linear   ROD 02-JUN-2024
DEFINITION  Rattus norvegicus nucleoporin 88 (Nup88), mRNA.
ACCESSION   NM_053616
VERSION     NM_053616.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2412)
  AUTHORS   Bonnin,E., Cabochette,P., Filosa,A., Juhlen,R., Komatsuzaki,S.,
            Hezwani,M., Dickmanns,A., Martinelli,V., Vermeersch,M., Supply,L.,
            Martins,N., Pirenne,L., Ravenscroft,G., Lombard,M., Port,S.,
            Spillner,C., Janssens,S., Roets,E., Van Dorpe,J., Lammens,M.,
            Kehlenbach,R.H., Ficner,R., Laing,N.G., Hoffmann,K.,
            Vanhollebeke,B. and Fahrenkrog,B.
  TITLE     Biallelic mutations in nucleoporin NUP88 cause lethal fetal
            akinesia deformation sequence
  JOURNAL   PLoS Genet 14 (12), e1007845 (2018)
   PUBMED   30543681
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2412)
  AUTHORS   Mizuguchi-Hata,C., Ogawa,Y., Oka,M. and Yoneda,Y.
  TITLE     Quantitative regulation of nuclear pore complex proteins by
            O-GlcNAcylation
  JOURNAL   Biochim Biophys Acta 1833 (12), 2682-2689 (2013)
   PUBMED   23777819
REFERENCE   3  (bases 1 to 2412)
  AUTHORS   Zemp,I. and Kutay,U.
  TITLE     Nuclear export and cytoplasmic maturation of ribosomal subunits
  JOURNAL   FEBS Lett 581 (15), 2783-2793 (2007)
   PUBMED   17509569
  REMARK    Review article
REFERENCE   4  (bases 1 to 2412)
  AUTHORS   Bodoor,K., Shaikh,S., Salina,D., Raharjo,W.H., Bastos,R., Lohka,M.
            and Burke,B.
  TITLE     Sequential recruitment of NPC proteins to the nuclear periphery at
            the end of mitosis
  JOURNAL   J Cell Sci 112 (Pt 13), 2253-2264 (1999)
   PUBMED   10362555
REFERENCE   5  (bases 1 to 2412)
  AUTHORS   Bastos,R., Ribas de Pouplana,L., Enarson,M., Bodoor,K. and Burke,B.
  TITLE     Nup84, a novel nucleoporin that is associated with CAN/Nup214 on
            the cytoplasmic face of the nuclear pore complex
  JOURNAL   J Cell Biol 137 (5), 989-1000 (1997)
   PUBMED   9166401
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from U93692.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: U93692.1, BC072524.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMD00132261,
                                           SAMD00132262 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2412
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="10"
                     /map="10q24"
     gene            1..2412
                     /gene="Nup88"
                     /gene_synonym="Nup84; Prei2"
                     /note="nucleoporin 88"
                     /db_xref="GeneID:113929"
                     /db_xref="RGD:620182"
     exon            1..320
                     /gene="Nup88"
                     /gene_synonym="Nup84; Prei2"
                     /inference="alignment:Splign:2.1.0"
     CDS             18..2246
                     /gene="Nup88"
                     /gene_synonym="Nup84; Prei2"
                     /note="nucleoporin Nup84; nucleoporin Nup88; 88 kDa
                     nuclear pore complex protein; 88 kDa nucleoporin;
                     preimplantation protein 2; nucleoporin 88kDa"
                     /codon_start=1
                     /product="nuclear pore complex protein Nup88"
                     /protein_id="NP_446068.1"
                     /db_xref="GeneID:113929"
                     /db_xref="RGD:620182"
                     /translation="MAAAAGPVGDGELWQSWLPNHVVFLRLREGLKNQSPAEADKPAT
                     STSPSCPPLPPHLPTRNLVFGLGGELFLWDAEGSAFLVVRLRGPSGGSVEPPLSQYQR
                     LLCINPPLFEIHQVLLSPTQHHVALIGTKGLMALELPQRWGKDSEFEGGKATVNCSTI
                     PIAERFFTSSTSLTLKHAAWYPSEMLDPHIVLLTSDNVIRIYSLREPQTPTKVIVLSE
                     AEEESLILNKGRAYTASLGETAVAFDFGPLVTVSKNMFEQKDREAVAYPLYILYENGE
                     TFLTYVSLLHSPGNIGKLLGPLPMHPAAEDNYGYDACAILCLPCVPNILVIATESGML
                     YHCVVLEGEEDDDQTLEKSWDPRADLIPSLYVFECVELELALKLASAEDDPFASDFSC
                     PIKLHRDPKCPSRYHCSHEAGVHSVGLTWIHKLHKFLGSDEEDKDSLQELTAEQKCFV
                     EHILCTKPLPCRQPAPIRGFWIVPDILGPTMICITSTYECLIRPLLSTVHPASPPLLC
                     TREDAGVAESPLRILAEAPDSFEKHIKRILQRSAANPALLKSSEKDLAPPPEECLQLI
                     SRATQVFREQYILKQDLAKEEIQRRVKLLCDQKRKQLEDLNYCREERKSLREMAERLA
                     DKYEEAKEKQEDIMNRMKKVLHSFHTQLPVLSDSERDMKKELQLIPDQLRHLGNAIKQ
                     VTMKKDYQQRKMEKVLSPQKPTITLSAYQRKCIQSILKEEGEHIREMVKQINDIRNHV
                     NF"
     exon            321..490
                     /gene="Nup88"
                     /gene_synonym="Nup84; Prei2"
                     /inference="alignment:Splign:2.1.0"
     exon            491..616
                     /gene="Nup88"
                     /gene_synonym="Nup84; Prei2"
                     /inference="alignment:Splign:2.1.0"
     exon            617..703
                     /gene="Nup88"
                     /gene_synonym="Nup84; Prei2"
                     /inference="alignment:Splign:2.1.0"
     exon            704..877
                     /gene="Nup88"
                     /gene_synonym="Nup84; Prei2"
                     /inference="alignment:Splign:2.1.0"
     exon            878..1064
                     /gene="Nup88"
                     /gene_synonym="Nup84; Prei2"
                     /inference="alignment:Splign:2.1.0"
     exon            1065..1212
                     /gene="Nup88"
                     /gene_synonym="Nup84; Prei2"
                     /inference="alignment:Splign:2.1.0"
     exon            1213..1311
                     /gene="Nup88"
                     /gene_synonym="Nup84; Prei2"
                     /inference="alignment:Splign:2.1.0"
     exon            1312..1402
                     /gene="Nup88"
                     /gene_synonym="Nup84; Prei2"
                     /inference="alignment:Splign:2.1.0"
     exon            1403..1504
                     /gene="Nup88"
                     /gene_synonym="Nup84; Prei2"
                     /inference="alignment:Splign:2.1.0"
     exon            1505..1663
                     /gene="Nup88"
                     /gene_synonym="Nup84; Prei2"
                     /inference="alignment:Splign:2.1.0"
     exon            1664..1789
                     /gene="Nup88"
                     /gene_synonym="Nup84; Prei2"
                     /inference="alignment:Splign:2.1.0"
     exon            1790..1855
                     /gene="Nup88"
                     /gene_synonym="Nup84; Prei2"
                     /inference="alignment:Splign:2.1.0"
     exon            1856..1936
                     /gene="Nup88"
                     /gene_synonym="Nup84; Prei2"
                     /inference="alignment:Splign:2.1.0"
     exon            1937..2063
                     /gene="Nup88"
                     /gene_synonym="Nup84; Prei2"
                     /inference="alignment:Splign:2.1.0"
     exon            2064..2182
                     /gene="Nup88"
                     /gene_synonym="Nup84; Prei2"
                     /inference="alignment:Splign:2.1.0"
     exon            2183..2412
                     /gene="Nup88"
                     /gene_synonym="Nup84; Prei2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agagctgttg gtccaagatg gcggctgccg cggggcctgt gggcgatggg gagctgtggc
       61 agagctggct tcctaaccac gtcgtgttct tgcgactccg cgaaggtctg aaaaaccaga
      121 gtccagccga agcggataaa ccagcgactt cgacttcacc ttcatgcccg cctctgccgc
      181 cgcatttgcc gacgagaaac ctggtcttcg gcctcggagg ggaactgttc ctgtgggacg
      241 cagaaggcag tgcctttttg gtggttcgcc ttcgaggccc cagtggtggc agcgtggagc
      301 cccctctctc ccagtatcag agattacttt gcattaatcc acccttgttt gaaattcatc
      361 aagtcttgtt aagtccaaca caacatcatg tagcacttat aggaacaaaa ggacttatgg
      421 cattagaatt acctcagaga tgggggaagg attctgaatt tgaaggtggg aaagcaactg
      481 tgaattgtag caccatcccg attgctgaga gatttttcac cagttctacc tctctgactc
      541 tgaagcatgc tgcatggtat cccagtgaga tgctggatcc ccacatagtg ctgttgacgt
      601 cagacaatgt gataagaatt tactctctgc gtgagcctca gacaccaact aaggtgattg
      661 tactttcgga agcagaagag gaaagtttaa tactcaataa aggaagagca tacacagcat
      721 ctctaggaga gacggcagtg gcgtttgact tcgggcctct ggtgaccgtc tcaaagaata
      781 tgtttgaaca gaaagacaga gaagcagtgg cgtatccact gtacattctg tatgagaacg
      841 gggagacctt cctcacctac gtcagcctgt tacacagccc agggaatatt gggaagctgt
      901 tgggcccact gcctatgcat cctgcagctg aagataacta tggttacgat gcctgtgcta
      961 tactctgttt gccctgtgtt cccaacatct tagtcattgc gactgagtca ggaatgctgt
     1021 accactgtgt tgtactagag ggagaagaag atgacgatca aacgttagaa aaatcctggg
     1081 atcccagggc cgacctcatc ccttctctgt acgtgtttga gtgtgttgag ttagaacttg
     1141 ccctgaaact ggcgtctgca gaggatgatc cctttgcttc tgacttttcc tgtccaatta
     1201 aactgcatag agatcccaag tgtccttcga gataccactg tagccatgaa gctggcgtac
     1261 acagcgttgg gctgacttgg attcacaaac tgcacaaatt ccttggatca gatgaagaag
     1321 acaaggatag tttacaggag ctcactgctg agcagaaatg ctttgtggag cacattcttt
     1381 gtacaaagcc gttgccatgc aggcagccag ctccaattcg aggattctgg atcgtcccgg
     1441 atatcctggg gcccacaatg atctgcatca ccagtaccta tgaatgtctc ataaggcctt
     1501 tattaagtac agtccaccca gcatctcctc ccctgctctg cacccgggaa gatgctggag
     1561 tggcagagtc tccactgcgc atcctggcgg aagccccaga ctcctttgag aagcatatta
     1621 aacgaatcct gcagcgcagc gccgccaacc cggcacttct caagtcatct gagaaggact
     1681 tggctccccc tcccgaggag tgtcttcagc tgatcagcag ggccacccag gtgttccgag
     1741 aacagtacat cctcaagcag gacctggcca aggaggagat tcagcggagg gtcaaattat
     1801 tatgtgacca gaagaggaag caactagaag atctcaatta ctgtcgagag gagagaaaaa
     1861 gtctccggga aatggccgag cgcttagctg acaaatatga agaagccaaa gaaaaacaag
     1921 aagatatcat gaacaggatg aaaaaagtgc ttcacagttt tcacactcag ctcccagtcc
     1981 tctcggacag tgagagagac atgaagaaag agctacagct gatacctgac caacttcgac
     2041 atctaggcaa tgccatcaaa caggttacta tgaaaaaaga ttatcaacag cgaaagatgg
     2101 aaaaagtgct gagtcctcag aaacccacca ttactctcag tgcctaccag cgaaagtgca
     2161 ttcagtccat cctgaaagaa gagggtgaac acatacgaga aatggtgaag caaatcaatg
     2221 atatccgaaa tcatgtcaac ttctgacacc acctgaagtt aaggacagct gaaggcttac
     2281 aagcccgtgc tgcagaacaa gcaggcagca taatctaatt tataaagacg aatttggata
     2341 aactatggtg tggttattct tttgttattc cttttgtttt ataatacttg aataaatttt
     2401 tattcaaaat tt
//
