LOCUS       NM_001168559            6553 bp    mRNA    linear   ROD 30-MAR-2024
DEFINITION  Rattus norvegicus nucleoporin 214 (Nup214), mRNA.
ACCESSION   NM_001168559 XM_001077983 XM_238325
VERSION     NM_001168559.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 6553)
  AUTHORS   Bonnet,A. and Palancade,B.
  TITLE     Regulation of mRNA trafficking by nuclear pore complexes
  JOURNAL   Genes (Basel) 5 (3), 767-791 (2014)
   PUBMED   25184662
  REMARK    Review article
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6553)
  AUTHORS   Natalizio,B.J. and Wente,S.R.
  TITLE     Postage for the messenger: designating routes for nuclear mRNA
            export
  JOURNAL   Trends Cell Biol 23 (8), 365-373 (2013)
   PUBMED   23583578
  REMARK    Review article
REFERENCE   3  (bases 1 to 6553)
  AUTHORS   Zemp,I. and Kutay,U.
  TITLE     Nuclear export and cytoplasmic maturation of ribosomal subunits
  JOURNAL   FEBS Lett 581 (15), 2783-2793 (2007)
   PUBMED   17509569
  REMARK    Review article
REFERENCE   4  (bases 1 to 6553)
  AUTHORS   Xu,L., Kang,Y., Col,S. and Massague,J.
  TITLE     Smad2 nucleocytoplasmic shuttling by nucleoporins CAN/Nup214 and
            Nup153 feeds TGFbeta signaling complexes in the cytoplasm and
            nucleus
  JOURNAL   Mol Cell 10 (2), 271-282 (2002)
   PUBMED   12191473
REFERENCE   5  (bases 1 to 6553)
  AUTHORS   Bogerd,H.P., Wiegand,H.L., Yang,J. and Cullen,B.R.
  TITLE     Mutational definition of functional domains within the Rev homolog
            encoded by human endogenous retrovirus K
  JOURNAL   J Virol 74 (20), 9353-9361 (2000)
   PUBMED   11000203
REFERENCE   6  (bases 1 to 6553)
  AUTHORS   Farjot,G., Sergeant,A. and Mikaelian,I.
  TITLE     A new nucleoporin-like protein interacts with both HIV-1 Rev
            nuclear export signal and CRM-1
  JOURNAL   J Biol Chem 274 (24), 17309-17317 (1999)
   PUBMED   10358091
REFERENCE   7  (bases 1 to 6553)
  AUTHORS   Bastos,R., Ribas de Pouplana,L., Enarson,M., Bodoor,K. and Burke,B.
  TITLE     Nup84, a novel nucleoporin that is associated with CAN/Nup214 on
            the cytoplasmic face of the nuclear pore complex
  JOURNAL   J Cell Biol 137 (5), 989-1000 (1997)
   PUBMED   9166401
REFERENCE   8  (bases 1 to 6553)
  AUTHORS   van Deursen,J., Boer,J., Kasper,L. and Grosveld,G.
  TITLE     G2 arrest and impaired nucleocytoplasmic transport in mouse embryos
            lacking the proto-oncogene CAN/Nup214
  JOURNAL   EMBO J 15 (20), 5574-5583 (1996)
   PUBMED   8896451
REFERENCE   9  (bases 1 to 6553)
  AUTHORS   Radu,A., Blobel,G. and Moore,M.S.
  TITLE     Identification of a protein complex that is required for nuclear
            protein import and mediates docking of import substrate to distinct
            nucleoporins
  JOURNAL   Proc Natl Acad Sci U S A 92 (5), 1769-1773 (1995)
   PUBMED   7878057
REFERENCE   10 (bases 1 to 6553)
  AUTHORS   Kraemer,D., Wozniak,R.W., Blobel,G. and Radu,A.
  TITLE     The human CAN protein, a putative oncogene product associated with
            myeloid leukemogenesis, is a nuclear pore complex protein that
            faces the cytoplasm
  JOURNAL   Proc Natl Acad Sci U S A 91 (4), 1519-1523 (1994)
   PUBMED   8108440
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000003.1.
            
            On or before Dec 12, 2009 this sequence version replaced
            XM_001077983.1, XM_238325.4.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMEA5760383,
                              SAMEA5760386 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-167               JAXUCZ010000003.1  35652879-35653045
            168-363             JAXUCZ010000003.1  35654845-35655040
            364-515             JAXUCZ010000003.1  35656056-35656207
            516-714             JAXUCZ010000003.1  35658129-35658327
            715-785             JAXUCZ010000003.1  35658910-35658980
            786-849             JAXUCZ010000003.1  35661143-35661206
            850-953             JAXUCZ010000003.1  35661614-35661717
            954-1060            JAXUCZ010000003.1  35667191-35667297
            1061-1127           JAXUCZ010000003.1  35668247-35668313
            1128-1254           JAXUCZ010000003.1  35669339-35669465
            1255-1416           JAXUCZ010000003.1  35670122-35670283
            1417-1876           JAXUCZ010000003.1  35673498-35673957
            1877-2052           JAXUCZ010000003.1  35674980-35675155
            2053-2150           JAXUCZ010000003.1  35676563-35676660
            2151-2237           JAXUCZ010000003.1  35680295-35680381
            2238-2387           JAXUCZ010000003.1  35680786-35680935
            2388-2546           JAXUCZ010000003.1  35682090-35682248
            2547-2650           JAXUCZ010000003.1  35684434-35684537
            2651-2833           JAXUCZ010000003.1  35688262-35688444
            2834-2907           JAXUCZ010000003.1  35689111-35689184
            2908-2991           JAXUCZ010000003.1  35689299-35689382
            2992-3261           JAXUCZ010000003.1  35693238-35693507
            3262-3423           JAXUCZ010000003.1  35694351-35694512
            3424-3523           JAXUCZ010000003.1  35696449-35696548
            3524-3599           JAXUCZ010000003.1  35703629-35703704
            3600-3678           JAXUCZ010000003.1  35704777-35704855
            3679-3766           JAXUCZ010000003.1  35708425-35708512
            3767-3825           JAXUCZ010000003.1  35711109-35711167
            3826-5580           JAXUCZ010000003.1  35713012-35714766
            5581-5651           JAXUCZ010000003.1  35717720-35717790
            5652-5805           JAXUCZ010000003.1  35725335-35725488
            5806-5955           JAXUCZ010000003.1  35729023-35729172
            5956-6127           JAXUCZ010000003.1  35733162-35733333
            6128-6267           JAXUCZ010000003.1  35736924-35737063
            6268-6292           JAXUCZ010000003.1  35737691-35737715
            6293-6553           JAXUCZ010000003.1  35738063-35738323
FEATURES             Location/Qualifiers
     source          1..6553
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="3"
                     /map="3p12"
     gene            1..6553
                     /gene="Nup214"
                     /gene_synonym="RGD1304977"
                     /note="nucleoporin 214"
                     /db_xref="GeneID:296634"
                     /db_xref="RGD:1304977"
     exon            1..167
                     /gene="Nup214"
                     /gene_synonym="RGD1304977"
                     /inference="alignment:Splign:2.1.0"
     CDS             123..6326
                     /gene="Nup214"
                     /gene_synonym="RGD1304977"
                     /note="nucleoporin 214kDa"
                     /codon_start=1
                     /product="nuclear pore complex protein Nup214"
                     /protein_id="NP_001162031.1"
                     /db_xref="GeneID:296634"
                     /db_xref="RGD:1304977"
                     /translation="MGDEMDAMIPEREMKDFQFRALKKVRIFDSPEELPKERSSVLTV
                     SNKYGMLFAGGTNGLNVFPTKSLLIQNKPGDDPNKIVDTIQGLNVPMKFPVHHLALSC
                     DNLTLSACMMSSEYGSIIAFFDVRTFSNQAKPLKRPFTYHKLSNGASGMVNDMKWNPT
                     VPSMAAVCLADGSISVLQVTDVVKVCATLPPSSGVTCVCWSPKGKQLAVGKQNGTVVQ
                     YLPTLQEKKVIPCPPFYEADHPVRVLDVLWIGTYVFTIVYAGADGALETCPDVVMALL
                     PKKEEKHPEIFVNFMEPCYSSCTERQHHYYLSYIEEWDLVLAASAASTEVSILARQSD
                     QTNWESWVLEDSSRAELPVTDKSDDSLPVGVAIDYTNEVEVAINEEKTLPPAPVLLLL
                     STDGVLCPFYMINQNPGVRSLIKTLELISAEGERQPKSSGSFPSTPPSPQAPQNLDAP
                     ATASSPLPPVSAAPTATFPLPSAGGGPSVFSFGPSPFKSSSIPGEPPPYPTGSDSSRA
                     APASGTPTFSFAPPSKGTLAPTPAVAPVPTSAAPFTFGSSGFKPPLESTPMSSAPNTG
                     MKPSFPPSTSSVKVNLNEKFTAVASSAPVHSSTSIPSVLPFSSSPKPPASGPLSHPTP
                     LPASPSSMPLKPSVSPSPSVGRSAQTAPSSAPSTGQKSPRVNPPVPKSGSSQARALQP
                     PVTEKQRHQWKESDPVMAGIGEEIAHFQKELEELKARTSKACFQVGTPEEMKMLRTES
                     DDLHTFLFEIREATESLHGDISTLKTTLLEGFAGVEEAREQHGRNHDSGYLHLLYKRP
                     LDPKSEAQLQEIRRLHQYVKFAVQDVNDVLDLEWDRHLEQKKRQRRLIVPERETLFNT
                     LANNREIINQQRKRLNHLVDSLQQLRLYNQTSPWNRPSTLSTQSDTPSFDSDLEHLLK
                     TTIESHTKPSPRVPGKLSPAKQAQLRNFLAKRKTPPVRSTAPASLSRSAFLSQRYYED
                     LDEGSSASSVAHPLEGEDARPTPTCREEEAVVPVPRHAPVVRTPSVQPSLLPQAMPFA
                     KPHLIHSSSPAAMSSSISTSATKVIPQGADTTMLATKTVKHGAPGPSHTVAAPQAAAA
                     AALRRQMASQAPAVSTLTESTLKNVPQVVNVQELKSNPSPPSAAMGSSGPHSAAKAPH
                     AVLTPVAASQAKQGSLINSFKPSGPTPVSCQLSSGDKAVGPGTAKTESPVTSTPSTGQ
                     LNKPFSFASPGTFTFGTITPAPSSSFTATPGAAPPTKESNQLEAFSFGGGGKPFCETI
                     PGNPPATGPPSAPSTSVTTTSLEDSAPTSSKPATPETPVSTASSKLETPPSKLGELLF
                     PSSLAGETLGSFSGLRVGQAEESTKPVSKASSTNLAGAQPAKPSGFSFPAASVLGKPV
                     EPSVTSSAPAAPVSALSASTSSSSATVFGSVPLTSAAPSGLMSFSGASLASSKASFSF
                     GNQQTSSAAAAAATPASTSVAPSLPASFPTLSFGGLLSSPSASSLPVSSGKITEEATP
                     PAVPDKSDHSEVSASTPSLPLQPPSAQLPQASLQTSDPVKKEPVPAQTTDSRPSSSAS
                     LVASTESTPVAPGGPDSKTEAVSPASTFAGPGPAVVAAVLLGAGSAASEASGTPSTSS
                     TVSSSTPTPATETAVFGTATSGSSVFTQPPAASSSSAFNQLSSNTATAPSATPVFGQV
                     AASIASTAAATPQASSSGFGSPAFGASAPGVFGQTAFGQSPAFGQATSSPASGFSFSQ
                     PGFSSVPAFGQSVSSTPTSTSANVFGATSSTSSPGSFSFGQASTNTGGTLFGQNNPPA
                     FGQSPGFGQGGSVFGSTSATTSTAAPSGFSFCQASGFGSSNTGSVFGQAASSGGSVFG
                     QSSTSSGSVFGSGNATRGGGFFSGLGGKPSQDAANKNPFSSASGGFGSTPTPNTSNLF
                     GNSGAKTFGGFGSSFGEQKPAGTFSSGGGSVASQGFGFSTPNKTGGFGAAPVFGSPPT
                     FGGSPGFGGVPAFGSAPAFTSPLGSTGGKVFGEGTAAASAGGFGFGSSSNTASFGTLA
                     SQNAPTFGSLSQQTSGFGTPSSGFSGFGSGTGAFTFGSSNSSVQGFGGWRS"
     exon            168..363
                     /gene="Nup214"
                     /gene_synonym="RGD1304977"
                     /inference="alignment:Splign:2.1.0"
     exon            364..515
                     /gene="Nup214"
                     /gene_synonym="RGD1304977"
                     /inference="alignment:Splign:2.1.0"
     exon            516..714
                     /gene="Nup214"
                     /gene_synonym="RGD1304977"
                     /inference="alignment:Splign:2.1.0"
     exon            715..785
                     /gene="Nup214"
                     /gene_synonym="RGD1304977"
                     /inference="alignment:Splign:2.1.0"
     exon            786..849
                     /gene="Nup214"
                     /gene_synonym="RGD1304977"
                     /inference="alignment:Splign:2.1.0"
     exon            850..953
                     /gene="Nup214"
                     /gene_synonym="RGD1304977"
                     /inference="alignment:Splign:2.1.0"
     exon            954..1060
                     /gene="Nup214"
                     /gene_synonym="RGD1304977"
                     /inference="alignment:Splign:2.1.0"
     exon            1061..1127
                     /gene="Nup214"
                     /gene_synonym="RGD1304977"
                     /inference="alignment:Splign:2.1.0"
     exon            1128..1254
                     /gene="Nup214"
                     /gene_synonym="RGD1304977"
                     /inference="alignment:Splign:2.1.0"
     exon            1255..1416
                     /gene="Nup214"
                     /gene_synonym="RGD1304977"
                     /inference="alignment:Splign:2.1.0"
     exon            1417..1876
                     /gene="Nup214"
                     /gene_synonym="RGD1304977"
                     /inference="alignment:Splign:2.1.0"
     exon            1877..2052
                     /gene="Nup214"
                     /gene_synonym="RGD1304977"
                     /inference="alignment:Splign:2.1.0"
     exon            2053..2150
                     /gene="Nup214"
                     /gene_synonym="RGD1304977"
                     /inference="alignment:Splign:2.1.0"
     exon            2151..2237
                     /gene="Nup214"
                     /gene_synonym="RGD1304977"
                     /inference="alignment:Splign:2.1.0"
     exon            2238..2387
                     /gene="Nup214"
                     /gene_synonym="RGD1304977"
                     /inference="alignment:Splign:2.1.0"
     exon            2388..2546
                     /gene="Nup214"
                     /gene_synonym="RGD1304977"
                     /inference="alignment:Splign:2.1.0"
     exon            2547..2650
                     /gene="Nup214"
                     /gene_synonym="RGD1304977"
                     /inference="alignment:Splign:2.1.0"
     exon            2651..2833
                     /gene="Nup214"
                     /gene_synonym="RGD1304977"
                     /inference="alignment:Splign:2.1.0"
     exon            2834..2907
                     /gene="Nup214"
                     /gene_synonym="RGD1304977"
                     /inference="alignment:Splign:2.1.0"
     exon            2908..2991
                     /gene="Nup214"
                     /gene_synonym="RGD1304977"
                     /inference="alignment:Splign:2.1.0"
     exon            2992..3261
                     /gene="Nup214"
                     /gene_synonym="RGD1304977"
                     /inference="alignment:Splign:2.1.0"
     exon            3262..3423
                     /gene="Nup214"
                     /gene_synonym="RGD1304977"
                     /inference="alignment:Splign:2.1.0"
     exon            3424..3523
                     /gene="Nup214"
                     /gene_synonym="RGD1304977"
                     /inference="alignment:Splign:2.1.0"
     exon            3524..3599
                     /gene="Nup214"
                     /gene_synonym="RGD1304977"
                     /inference="alignment:Splign:2.1.0"
     exon            3600..3678
                     /gene="Nup214"
                     /gene_synonym="RGD1304977"
                     /inference="alignment:Splign:2.1.0"
     exon            3679..3766
                     /gene="Nup214"
                     /gene_synonym="RGD1304977"
                     /inference="alignment:Splign:2.1.0"
     exon            3767..3825
                     /gene="Nup214"
                     /gene_synonym="RGD1304977"
                     /inference="alignment:Splign:2.1.0"
     exon            3826..5580
                     /gene="Nup214"
                     /gene_synonym="RGD1304977"
                     /inference="alignment:Splign:2.1.0"
     exon            5581..5651
                     /gene="Nup214"
                     /gene_synonym="RGD1304977"
                     /inference="alignment:Splign:2.1.0"
     exon            5652..5805
                     /gene="Nup214"
                     /gene_synonym="RGD1304977"
                     /inference="alignment:Splign:2.1.0"
     exon            5806..5955
                     /gene="Nup214"
                     /gene_synonym="RGD1304977"
                     /inference="alignment:Splign:2.1.0"
     exon            5956..6127
                     /gene="Nup214"
                     /gene_synonym="RGD1304977"
                     /inference="alignment:Splign:2.1.0"
     exon            6128..6267
                     /gene="Nup214"
                     /gene_synonym="RGD1304977"
                     /inference="alignment:Splign:2.1.0"
     exon            6268..6292
                     /gene="Nup214"
                     /gene_synonym="RGD1304977"
                     /inference="alignment:Splign:2.1.0"
     exon            6293..6553
                     /gene="Nup214"
                     /gene_synonym="RGD1304977"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cgcgcgcccc tggcgctgaa ggaaggaagt tgaggcctga gcggcctggg ctgtgtttga
       61 aaggccgcgg acgctagcgg cagcggcagc agcagctact tggacatcct gaaggcggcc
      121 cgatgggaga cgagatggat gccatgatcc ctgagcggga gatgaaggac tttcagttta
      181 gagctctgaa gaaagtgaga atctttgact ctcctgagga gttgcccaag gagcgctcga
      241 gtgtgctcac cgtatccaat aagtatggca tgctctttgc tggtggcacc aatggcttga
      301 atgtctttcc tactaaaagc cttcttatcc aaaacaaacc tggagatgat cccaataaaa
      361 ttgttgacac aatccaaggc ttgaatgtcc ctatgaaatt cccagttcat cacctggcac
      421 tgagctgtga taaccttaca ctctctgcgt gcatgatgtc cagtgaatat ggctccatta
      481 tagccttttt tgatgttcgc acattttcaa atcaggctaa accactgaaa cgcccattta
      541 cctatcacaa gctttcaaac ggtgccagcg ggatggtgaa tgatatgaag tggaacccca
      601 ctgtcccttc catggcagca gtttgtctgg ctgatggcag catttctgtc ttgcaagtta
      661 cggatgtggt gaaagtgtgc gccacacttc ctccttcatc gggagtcacg tgtgtatgct
      721 ggagccccaa aggaaagcag ctggccgtgg gaaagcagaa tggaactgtg gtccagtatc
      781 ttcctacatt gcaggaaaaa aaggtcattc catgtcctcc gttttatgag gcagaccacc
      841 ctgtcagagt tctggatgtg ctgtggattg gtacatacgt cttcacgata gtctatgctg
      901 gtgcggatgg cgcactggag acctgtccag atgtggtgat ggctctgctt ccgaaaaaag
      961 aagaaaagca cccagaaata tttgtgaact tcatggagcc ctgctacagc agctgcacag
     1021 agagacaaca tcattactac ctcagctaca tcgaggagtg ggatttagtg ctggcagcat
     1081 ctgcagcgtc aacagaagtt agcatccttg ctcgacaaag tgatcagact aattgggaat
     1141 cttgggtact ggaagactct agtcgagctg aactgcctgt gacagacaag agcgatgact
     1201 ccttgcccgt gggtgttgcc atagattaca ccaatgaagt agaagttgcc atcaatgaag
     1261 aaaagactct tcctcctgct ccggttctcc tgttactttc aacagatggt gtactttgtc
     1321 cattttatat gatcaatcaa aatcccgggg ttaggtccct aatcaagacc ttagagctga
     1381 tctcagcaga gggagagcgc cagcctaagt cctcaggaag ttttcctagt acaccacctt
     1441 cccctcaagc tccacagaac cttgacgctc cagcaacagc ctcttcgcct cttccaccgg
     1501 tgtctgctgc tcccaccgcc accttccctt tgccgtctgc tggaggaggc ccttctgtgt
     1561 tctcctttgg cccttcaccc ttcaagtcct cctccatccc cggggagccc ccgccatacc
     1621 ccactggctc tgacagttcc agagcagcac cagcctctgg cacccccacc ttctcttttg
     1681 cgcctccttc caaaggcacc ttggccccga cccctgcagt ggctcctgtg cccacatctg
     1741 ctgctccctt cactttcgga tcatcaggtt ttaagccccc cttggaaagc acacctatgt
     1801 ccagtgcccc aaacacaggg atgaagcctt cattcccacc ctcaacttct tcggtgaaag
     1861 tcaacctgaa cgagaagttc accgctgtgg cctcctctgc acccgttcat agctccacaa
     1921 gcataccctc cgtgttgccg ttctcttcct cccccaagcc accagcttct ggaccactca
     1981 gccatcccac gcctctccca gcatcaccca gctccatgcc tttgaaacct tcagtctctc
     2041 cctctccgtc agttggccgc tccgcccaga ctgccccgag ttcagcaccc tccacagggc
     2101 agaaatctcc tagggtaaat cctccagtgc caaagtcagg gtcctctcag gccagagcac
     2161 ttcagcctcc tgttacagag aagcagaggc atcagtggaa agagtcagac cctgtgatgg
     2221 ctggaattgg agaggagatt gcacacttcc agaaagagct ggaggagtta aaggcgcgaa
     2281 cctccaaagc ctgtttccag gtcggcaccc ctgaggagat gaagatgctg cgcacagagt
     2341 cagacgacct gcacaccttc ctctttgaga tcagagaggc cacagagtct cttcatggag
     2401 acataagtac actgaaaaca actctgctgg agggctttgc tggtgttgaa gaagccagag
     2461 aacagcatgg aagaaatcat gactctgggt atctccatct gctttataaa agaccactgg
     2521 atcccaagag cgaggcccag ctccaggaaa ttcgccgcct tcaccagtat gtgaaatttg
     2581 ctgtccagga tgtgaatgat gtcctagact tagagtggga tcggcatctg gagcagaaga
     2641 aaagacagag gcgcctaatt gtgccagaga gagagacact tttcaacaca ctagccaaca
     2701 accgggaaat catcaaccag cagaggaaga ggttgaatca cctggtggac agtctgcagc
     2761 agctccgtct ctataaccag acgtccccat ggaaccggcc ctcaacgctt tcaacgcaaa
     2821 gtgacactcc tagttttgac agtgaccttg aacacctgct aaagactacc attgaatctc
     2881 acaccaagcc ttctcctaga gtgccaggta aactgtcccc tgcgaaacag gcccaactga
     2941 ggaacttctt ggccaaaagg aagaccccac cagtgaggtc tactgctcca gccagcctgt
     3001 ctcggtcagc cttcctgtct cagaggtact atgaagactt agatgaaggc agctccgcgt
     3061 cgtccgtagc tcaccctctg gagggagaag atgcccggcc gacgccgacc tgcagagagg
     3121 aggaggctgt ggtcccagtc cctcggcatg cccccgtggt ccgcacacct tctgtccaac
     3181 ccagtctcct gcctcaggcg atgccttttg caaagcctca cctgattcat agttcttcac
     3241 ctgctgcgat gagctcttca atctctacgt cagctaccaa agttattcct caaggagccg
     3301 acaccacaat gctggcaact aaaacggtaa agcatggtgc accaggtcct tcccacactg
     3361 tcgcagctcc ccaggcagcg gctgctgcag ccctgagacg gcagatggcc agtcaggcgc
     3421 cagctgtgag cactctgacc gaatccactt tgaagaatgt ccctcaagtg gtgaatgtac
     3481 aggaactgaa gagtaacccc tcaccccctt ctgcggccat gggttcttct gggccgcact
     3541 cagcagccaa agccccccat gcagtgttaa ccccagtggc tgccagccaa gccaagcagg
     3601 ggtctctgat aaattccttc aagccgtcag gacccacacc agtgtcctgt cagctgtcct
     3661 ctggggataa agctgtaggt ccagggacgg ccaagacaga gtcacctgtg acctccaccc
     3721 catctacggg gcagctcaac aagcctttct cattcgcctc cccagggacc tttacttttg
     3781 ggacaatcac accagcccca tcttctagtt tcactgccac accaggggca gcacccccca
     3841 ctaaagagtc aaaccagctt gaggcgttct catttggcgg gggaggcaaa cctttttgtg
     3901 agaccattcc tggaaacccc cctgccacgg gacccccatc agcacccagc acttctgtaa
     3961 caactacgtc tctggaagac tctgctccaa ccagcagcaa acctgcaact cctgaaactc
     4021 ctgtgtccac tgcctctagc aaattggaaa ctccaccatc caagttagga gagcttctct
     4081 tcccaagttc tctagctgga gagacgctag ggagcttctc aggactgcgt gttggccagg
     4141 ctgaggagtc tacaaagccc gttagtaagg cctcctccac aaacctggcc ggagcccagc
     4201 cagccaagcc ctcagggttt agctttcctg ctgcttccgt gttagggaag ccagtggagc
     4261 ccagtgtgac gtcctctgcc ccagcggcac cagtctcagc tctgagtgcg agcactagca
     4321 gttcctcggc aactgtcttt ggcagtgtgc cccttaccag tgctgcacct tccgggctca
     4381 tgagttttag tggggcctct ttggctagta gcaaagctag tttctcattt ggaaaccaac
     4441 agactagtag tgcagcagca gcagcagcta ccccagcatc cacctcagtt gccccttccc
     4501 ttccagcatc tttccctact ttgtcatttg gtggcctcct gagttcacca tcagcttctt
     4561 ccctgcctgt gtcttctggt aagatcacag aggaggccac accaccagct gtgcctgaca
     4621 agtcagacca cagtgaagtg tcagcatcaa caccctcact tccactacag ccaccgtcag
     4681 cccagcttcc ccaggcatct ctgcaaactt ctgaccctgt caaaaaagaa cctgttcctg
     4741 cgcagaccac agacagcaga ccatcatctt ctgccagcct tgtggcatcc acagaatcca
     4801 ctccagtcgc cccagggggc cctgatagca agacagaagc agtgtcccct gcttccacct
     4861 ttgcagggcc tgggccggcc gtggttgcag ctgttctcct aggagcaggc tcggcagcca
     4921 gtgaagcttc cggtacccct agtacctcca gcactgtctc cagcagtacc ccaactcctg
     4981 ccacagagac agctgtattt gggactgcca cttctggctc ctcagtcttt acacagccgc
     5041 ctgctgccag ttcgagctca gcattcaacc agctctccag taacacggcc actgcaccct
     5101 ccgccacccc cgtgtttggg caagtggcag ccagcatagc cagcacagcc gctgccacgc
     5161 cacaggccag cagttcagga tttggcagcc ctgcgtttgg tgcttcggct cctggagtgt
     5221 tcggacagac agcatttggg cagtccccag cctttgggca agcaacaagc agccctgcga
     5281 gtggcttctc cttcagccaa cctgggttca gctctgtccc tgcttttggc cagtctgtct
     5341 cctccacccc cacatccacc agtgccaatg tcttcggagc cacctcaagt accagcagcc
     5401 ctggttcctt ctcatttgga caggcttcta ccaatacagg agggacgcta tttggccaaa
     5461 acaaccctcc tgcttttggt cagagcccgg gctttgggca gggaggctct gtgtttggta
     5521 gcacctcggc cactacctct acagcagcac cttcagggtt tagcttttgt caagcctccg
     5581 gttttgggtc tagtaatact ggttctgtgt ttggtcaggc agccagtagc ggtgggtcag
     5641 tctttggcca gtcatccact tccagtggca gcgtgtttgg gtctggaaat gctacaagag
     5701 ggggcggttt cttcagtggc cttggaggaa aacccagcca ggatgctgcc aacaaaaacc
     5761 cattcagctc ggccagtggg ggctttgggt ctacgcctac acccaatacc tctaacctgt
     5821 tcgggaacag cggagctaag accttcggag ggttcggctc ctccttcggg gagcagaagc
     5881 ctgctggcac attcagctct ggtggtggga gcgtggcatc ccaaggtttt ggattttcca
     5941 ctccaaataa aacaggtggc ttcggtgctg ctccagtgtt tggcagccct cctacttttg
     6001 ggggatcccc tgggtttgga ggggtgccag cattcggttc agccccagcc tttacaagcc
     6061 ctctgggctc gacgggaggc aaagtgttcg gagagggtac tgcggccgcc agcgcaggag
     6121 gattcgggtt cgggagtagc agcaacactg catccttcgg taccctcgcc agtcagaacg
     6181 cacccacttt cggatccttg tcccagcaga cctctggctt cgggaccccg agcagtggat
     6241 tctctgggtt tggatcaggc acaggagcat tcaccttcgg atcatctaac tcgtctgtcc
     6301 agggcttcgg tggctggaga agctgagccg acgtcagcct tccctgaggc tgctgtgagc
     6361 tcctgtaggc agccctccac tctccaggcg cccacaggaa cagactctca gaagaactct
     6421 catgaagatg ctccgccagg aagaagcatt ggagaccaaa gctcagcagt gcttgactgc
     6481 ctcttcccca ccttcagatt ttgcatcaag ttttcctctg ctattaaagt gtttgggctg
     6541 gttctgcaca gaa
//
