LOCUS       XM_006233905            5728 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus nucleoporin 188 (Nup188), transcript
            variant X1, mRNA.
ACCESSION   XM_006233905
VERSION     XM_006233905.3
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051338.1) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Feb 22, 2024 this sequence was replaced by
            XM_006233905.4.
            
            On Jan 21, 2021 this sequence version replaced XM_006233905.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5728
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="3"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..5728
                     /gene="Nup188"
                     /note="nucleoporin 188; Derived by automated computational
                     analysis using gene prediction method: Gnomon. Supporting
                     evidence includes similarity to: 1 mRNA, 69 ESTs, 3 long
                     SRA reads, 1 Protein, and 100% coverage of the annotated
                     genomic feature by RNAseq alignments, including 126
                     samples with support for all annotated introns"
                     /db_xref="GeneID:366016"
                     /db_xref="RGD:1306022"
     CDS             97..5361
                     /gene="Nup188"
                     /codon_start=1
                     /product="nucleoporin NUP188 isoform X1"
                     /protein_id="XP_006233967.1"
                     /db_xref="GeneID:366016"
                     /db_xref="RGD:1306022"
                     /translation="MAAAAGGPCVRSSRELWTILLGRSALRELNQIEAELNKHWQRLL
                     EGLSYYRPPSPSSAERVKANKDVASPLKELGLRVSKFLGLDEEQSVQLLQCYLQEAYR
                     GTRDSLKTVLQDERQSQALTLKIADYYYEERTCILRCVLHLLTYFQDERHPYRAEYAD
                     CVDKLEKELVLKYRQQFEELYRTEAPTWETHGNLMTERQVSRWFVQCLREQSMLLEII
                     FLYYAYFEMAPSDLLVLTKMFKEQGFGSRQTNRHLVDETMDPFVDRIGYFSALILVEG
                     MDIESLHKYALDDRRELHQFAQDGLICQDMDRIMLTLGDIPHHAPVLLAWALLRHTLN
                     PEETSSVVRKIGGTAIQLNVFQYLTRLLRSLASGGNDCTTSTACMCVYGLLSFALTSL
                     ELHTLGNQQDVIDTACEVLADPSLPELFWGTEPTSGLGIILDSVCGMFPHLLSPLLQL
                     LRALVSGKSTAKKVYSFLDKMSFYNELHKHKPHDVLSHEDGTLWRRQTPKLLYPLGGQ
                     TNLRIPQGTVGQVMLDDRAYLVRWEYSYSSWTLFTCEIEMLLHVVSTADVIQHCQRVK
                     PIIDLVHKVISTDLSIADCLLPITSRIYMLLQRLTTVISPPVNVIASCVNCLTVLAAR
                     NPAKVWTDLRHTGFLPFVAHPVSNMTQMISAEGMNAGGYGSLLMNSEQPQGEYGVTVA
                     FLRLVTTLVKGQLGSTQSQGLVPCVMFVLKEVLPSYHKWRYSSHGVRELIGCLILELI
                     HAILNLCQETELHSSHTPSLPSLCICSLAYTEAGQTVISIMGIGVDTIDMVMAAQPRS
                     DGPEGQGQGQLLIKTVKLAFSVTNNVIRLKPPSNVVSPLEQALTQHGAHGNNLIAVLA
                     KYIYHRHDPALPRLAIQLLKRLATVAPMSVYACLGSDAAAIRDAFLTRLQSKIEDMRI
                     KVMILEFLTVAVETQPGLIELFLNLEVKDGSSGSKEFSLGVWSCLHVVLELIDSQQQD
                     RYWCPPLLHRAAIAFLHALWQDRRDSAMLVLRTKPRFWENLTSPLFGTLSPPSETSEP
                     SILETCALIMKIICLEIYYVVKGSLDQSLKDTLKKFSSEKRFAYWSGYVKSLAVYMAE
                     TEGNSCTSLLEYQMLVSAWRTLLIVATSHADIMNLTDVAVRRQLFLDVLDGTKALLLV
                     ATSVNCLRLGSMMCTLLLILLRQWKRELGAVDKILGPLTEVLEGVLQADQQLMEKTKA
                     KVFSAFITVLQMKELRVSEIPQYSQLVLNVCETLQEEVIALFDQTRHSLASGSAAEDK
                     DSMETDDCPRPRHKDQRDGQVCVLGLHLAKELCEVDEDGDSWLQVTRRLPILPTLLTT
                     LEVSLRMKQNLHFTEAALHLLLTLARTQQGATAVAGAGITQSICLPLLSVYQLSSNGT
                     GQTPSTSRKSLDAPSWPGVYRLSMSLMERLLKTLRYNFLTEALDFVGVHQERTLQCLN
                     AVRTVQSLACLEEADHTVGFILQLSHFRKEWHFHLPQLMRDVQVNLGYLCQACTSLLH
                     SRKMLQHYLQNKNGDGLPSAVTPRVHRPSTTTTVLATPSGCSSKQPIADTEASEQRAL
                     HTVQYGLLKILSRTLAALRHFTPDVCQILLDQSLDLAEYNFLFALSFTTPTFDSEVAP
                     SFGTLLATVNVALNMLGELDKKKESLTQAVGLSTQAEGTRTLKSLLMFTMENCFYLLI
                     SQAVRYLRDPAVHPRDKQRMKQELSSELSTLLSSLSRYFRRGAPSSPAAGVLPSPQGK
                     ATSLSKASPESQEPLIQLVQAFVRHVQR"
ORIGIN      
        1 caccaccacg tgattgaaaa cccaggcccc cggtctggcg gcgcacggtc acgtgggtgc
       61 agcgtatagg ggcggggctg ggacgcgcgc gcgaagatgg cggctgccgc cggtgggccg
      121 tgtgtgagga gcagtagaga actctggacg attctcctcg ggaggtcagc tcttagagaa
      181 ttgaaccaga ttgaggcgga actgaacaaa cactggcagc ggttgttaga gggtctttct
      241 tactacagac ctcccagtcc aagctcagct gaaagagtga aggctaataa agatgtggcg
      301 tcacctctga aggagctggg cttaagagtc agcaagttct tgggtctgga cgaggagcag
      361 agcgtgcagt tgctgcagtg ttaccttcag gaggcctaca ggggtactcg ggactcactg
      421 aagacagtcc tgcaagatga gaggcagagc caggccttaa ccctgaagat tgcagattac
      481 tattacgaag aaagaacctg cattcttcgc tgtgtcttac accttctgac atatttccaa
      541 gatgagcgcc atccctacag ggccgaatat gctgactgtg ttgacaaact agagaaggag
      601 ctagttttaa agtaccgaca gcagtttgag gagctgtata gaacagaagc accgacttgg
      661 gagacgcatg gcaacctcat gactgagcgt caggtgtctc ggtggtttgt tcagtgcctc
      721 cgggaacagt ccatgctact agaaattatt ttcctctatt atgcatactt cgagatggca
      781 cctagtgacc tactggtact taccaagatg ttcaaggagc aagggtttgg tagtaggcag
      841 accaatagac accttgtgga tgaaaccatg gatccctttg tagatcgcat tgggtacttc
      901 agtgccctta tcctggtgga aggcatggat attgaatcct tgcacaagta cgcgctggac
      961 gacaggagag agctgcacca gtttgcccag gatgggctta tctgccagga tatggatcgt
     1021 ataatgttga ccctgggaga cattccacac catgcccctg tgcttttggc ctgggctctc
     1081 ctccgtcaca cactgaaccc agaagagacc agcagtgtgg tcaggaagat agggggcacg
     1141 gccatccagc tgaatgtgtt tcagtacttg actcgactgc tccggtcact tgccagcggt
     1201 gggaatgatt gcaccacgag taccgcctgc atgtgtgtct acggtcttct ctcctttgct
     1261 ctcacctcac tggagctgca cacactgggc aaccagcagg atgtaattga cacagcatgt
     1321 gaagtcctgg cagacccttc tcttccagag cttttctggg gaacagagcc aacctctggt
     1381 cttgggatca ttctggacag tgtgtgtggg atgtttcccc atctcctttc cccacttcta
     1441 caattgctcc gagccctcgt gtcagggaag tccactgcca aaaaggtgta cagtttccta
     1501 gataaaatgt ctttctacaa tgaacttcat aagcacaagc cccatgacgt gctctctcac
     1561 gaggatggaa cgctgtggcg gaggcaaacg cccaaactcc tgtaccctct agggggtcag
     1621 accaaccttc gaattcctca gggcactgtg ggccaagtca tgctggatga tagggcttac
     1681 cttgtacgct gggaatactc ctacagtagc tggaccctct tcacctgcga gattgaaatg
     1741 ctactccacg ttgtctccac agcagatgtg atccagcatt gccagcgggt caagcccatc
     1801 attgatttgg ttcacaaggt catcagcaca gacctgtcca tagcagactg cctgctgccc
     1861 atcacatccc gcatctacat gctgctgcag cggttgacga cggtgatctc ccctccggta
     1921 aacgtcattg cttcttgtgt caactgctta actgtcttgg ctgctcgaaa tccagcaaag
     1981 gtctggactg atcttcgtca cacaggtttt ttgccatttg tggcccaccc tgtctccaac
     2041 atgactcaga tgattagtgc ggaggggatg aacgctggag ggtatggcag ccttctgatg
     2101 aacagtgagc agccccaggg cgagtatggg gtcaccgttg cctttctgcg cctggtcacc
     2161 actcttgtca agggacagct cggtagtacc cagagccaag gcctggtgcc ctgcgtgatg
     2221 ttcgtgttga aggaggtgct tcccagctat cacaaatggc gctacagctc tcacggcgtg
     2281 cgggagctca taggttgcct gattctggag ctgattcatg caatactgaa cctgtgccaa
     2341 gagacagagc tgcatagcag ccacacgccc agcctgcctt ccctctgcat ctgcagcctg
     2401 gcttataccg aggctggaca gactgtcatc agcatcatgg gaattggtgt ggacaccata
     2461 gacatggtga tggctgctca gccccgcagt gatgggccag aaggtcaggg ccagggccaa
     2521 ctgctgatca agacagtgaa gctggcgttc tctgtcacca acaatgttat tcggctgaag
     2581 cctccttcta atgtggtgtc ccccctggaa caggctctca cacagcatgg tgcccatggg
     2641 aacaacctta ttgctgtcct agccaagtac atctaccaca gacatgaccc agctttgcca
     2701 cgcctggcca tccagctgct gaaacgtttg gccacggtag ccccaatgtc agtgtatgct
     2761 tgcctgggca gtgacgcagc tgccatccgt gatgccttcc tgacccgcct tcagagcaag
     2821 attgaggaca tgcgcatcaa agtcatgatc ctggagttcc ttacagtggc tgtggagacc
     2881 cagccaggcc tcatcgagct gtttctgaat ctggaggtga aggacggcag cagtggctcc
     2941 aaggaattca gccttggcgt gtggagttgt ctccatgtgg tgctggagct gatcgactcc
     3001 cagcagcagg atcgatactg gtgcccacct ctgctgcacc gtgcagccat cgccttcctt
     3061 cacgccctgt ggcaggaccg tagggacagt gccatgctcg tcctcagaac caaacccagg
     3121 ttttgggaga atttaacgag tccgctgttt ggaactctct ctcctccttc agagacatct
     3181 gagcccagca tcctggaaac ctgtgccctc atcatgaaga taatatgttt ggagatctac
     3241 tatgtagtta agggttcatt ggaccagtca ttaaaagata cactcaagaa gttttccagt
     3301 gagaaacgct ttgcctactg gtcggggtac gtcaagtctc tggcagttta catggctgag
     3361 acagagggca acagctgcac gtccttgcta gagtatcaga tgctggtgtc cgcctggagg
     3421 acgcttctca tcgttgctac cagtcacgca gacatcatga acttgactga cgtggcagtg
     3481 cggcgccagc tttttcttga tgtgcttgac gggaccaaag cattactcct tgtggcaaca
     3541 tcagtgaact gcctccggct gggctccatg atgtgcactc tgctgctcat cctcctgcgg
     3601 cagtggaaga gagagctggg tgctgtggat aaaatccttg ggcccttgac agaggtcctg
     3661 gaaggggtgc tccaggcaga ccagcagctc atggagaaga ccaaggccaa ggtgttctct
     3721 gcattcatca cagtgttaca gatgaaggag cttcgagtaa gcgaaatccc ccagtactcc
     3781 cagctggtgc tgaatgtctg cgagaccctc caggaagagg tgattgcact ctttgaccag
     3841 acccgccaca gcctggcatc aggcagtgct gccgaagaca aagacagcat ggaaacagat
     3901 gactgccctc ggccccggca caaggaccag cgtgacgggc aggtatgtgt cctgggactg
     3961 catctggcaa aggagctctg tgaggtggat gaggatgggg actcgtggct gcaggtgacc
     4021 cgaaggctcc ccattctgcc cacgctgctc accaccctgg aggtgagcct ccgcatgaag
     4081 cagaacctgc attttactga ggctgcgctg cacctgctcc tcaccctggc tcgcacccag
     4141 cagggagcca cagcagtggc tggagctggc atcacgcaga gcatctgctt gcccctcttg
     4201 agtgtatacc agctgagcag caatggcaca ggacagacac ccagcacctc tcgaaagtcc
     4261 ctggatgccc cgtcctggcc aggagtttac cgcctctcca tgtccttgat ggagcggttg
     4321 ctcaagactc tacgctacaa tttcctgact gaggccctag actttgtggg tgtccatcag
     4381 gagcggacct tgcagtgtct caatgccgtg aggacagtac agagtctagc ctgcctggag
     4441 gaggcagatc acactgtggg cttcatccta caactgtccc acttcaggaa ggagtggcac
     4501 ttccacctgc ctcagctcat gcgtgatgtt caggtgaacc tgggttactt gtgccaggcc
     4561 tgcacttccc tcctacacag tcgcaagatg ctgcagcact acctacagaa caaaaatggc
     4621 gatggcctcc cttcggctgt cactccccga gttcatcggc catccaccac caccaccgtt
     4681 ctggctaccc catctggctg ctcctccaag cagcctattg ctgacactga ggcctcagaa
     4741 cagcgagcct tacacacagt ccagtatggc cttctcaaga ttctcagcag gaccctggca
     4801 gccctgcgcc acttcactcc ggatgtctgc cagatcctgc tggaccagtc cctggatctt
     4861 gctgagtaca actttctatt tgccctgagt ttcaccactc ccacttttga ctctgaagta
     4921 gccccctcct tcggaaccct cttggccaca gtgaatgtgg ccctcaacat gcttggagag
     4981 ctggacaaga aaaaggaatc cctcacccag gcggtgggcc tcagcacaca agcagaaggg
     5041 acccggacat taaagtccct cctgatgttc accatggaga actgcttcta tctgctcatc
     5101 tcccaagcag tacgctacct cagggacccg gctgtgcacc cccgggacaa gcagcggatg
     5161 aagcaggagc tgagctcaga gctgagcaca ttgctttcca gcctctcacg ttacttcaga
     5221 aggggagccc ccagctcccc tgctgctgga gtcctgccct caccacaggg caaagccacc
     5281 tctctatcca aagctagccc agagtctcag gagcctctga tccaacttgt gcaagccttt
     5341 gtccggcacg tgcagagata gggcaaagga gggctgtcta cttgctgctc cctcccagcc
     5401 tgcactgcag cctgggcaga ggctgctgcc actgagcaag ccactccctt cgtcctcctc
     5461 acgcccgccc gctgacatta tttttatata gctgaagagg tcaacagcac gggcagagga
     5521 caaagggtct gggtgctcag actgacagca ccctaaggtg gccccgtcct ctgagcgttc
     5581 ccgtggcact taaccagcca gggaggccca gggtgccgca gcacaggaga gacctgtgtg
     5641 agtgagggtt ttccatgatc tattcttgca gtttttttga taatactgtg gtctatttat
     5701 acaaatatta aaagtgctgt ttatagac
//
