LOCUS       NM_001399417            3217 bp    mRNA    linear   ROD 08-DEC-2024
DEFINITION  Rattus norvegicus nudix hydrolase 4 (Nudt4), transcript variant 1,
            mRNA.
ACCESSION   NM_001399417 XM_006241282
VERSION     NM_001399417.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3217)
  AUTHORS   Song,M.G., Li,Y. and Kiledjian,M.
  TITLE     Multiple mRNA decapping enzymes in mammalian cells
  JOURNAL   Mol Cell 40 (3), 423-432 (2010)
   PUBMED   21070968
REFERENCE   2  (bases 1 to 3217)
  AUTHORS   Hua,L.V., Green,M., Warsh,J.J. and Li,P.P.
  TITLE     Molecular cloning of a novel isoform of diphosphoinositol
            polyphosphate phosphohydrolase: a potential target of lithium
            therapy
  JOURNAL   Neuropsychopharmacology 24 (6), 640-651 (2001)
   PUBMED   11331144
REFERENCE   3  (bases 1 to 3217)
  AUTHORS   Caffrey,J.J., Safrany,S.T., Yang,X. and Shears,S.B.
  TITLE     Discovery of molecular and catalytic diversity among human
            diphosphoinositol-polyphosphate phosphohydrolases. An expanding
            Nudt family
  JOURNAL   J Biol Chem 275 (17), 12730-12736 (2000)
   PUBMED   10777568
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000007.1.
            
            On Jan 7, 2022 this sequence version replaced XM_006241282.4.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643297.24873.1,
                                           SRR26643286.22409.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760389, SAMN12840108
                                           [ECO:0000348]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-494               JAXUCZ010000007.1  32090998-32091491   c
            495-605             JAXUCZ010000007.1  32079572-32079682   c
            606-650             JAXUCZ010000007.1  32079099-32079143   c
            651-738             JAXUCZ010000007.1  32077699-32077786   c
            739-3217            JAXUCZ010000007.1  32074978-32077456   c
FEATURES             Location/Qualifiers
     source          1..3217
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="7"
                     /map="7q13"
     gene            1..3217
                     /gene="Nudt4"
                     /gene_synonym="DRCF-5"
                     /note="nudix hydrolase 4"
                     /db_xref="GeneID:94267"
                     /db_xref="RGD:621355"
     exon            1..494
                     /gene="Nudt4"
                     /gene_synonym="DRCF-5"
                     /inference="alignment:Splign:2.1.0"
     CDS             399..941
                     /gene="Nudt4"
                     /gene_synonym="DRCF-5"
                     /EC_number="3.6.1.52"
                     /EC_number="3.6.1.61"
                     /note="isoform 1 is encoded by transcript variant 1;
                     nudix-type motif 4; diphosphoinositol polyphosphate
                     phosphohydrolase 2; DIPP-2; rDIPP2; nudix motif 4;
                     nucleoside diphosphate-linked moiety X motif 4;
                     diadenosine 5',5'''-P1,P6-hexaphosphate hydrolase 2;
                     diphosphoinositol polyphosphate phosphohydolase type II;
                     nudix (nucleoside diphosphate linked moiety X)-type motif
                     4"
                     /codon_start=1
                     /product="diphosphoinositol polyphosphate phosphohydrolase
                     2 isoform 1"
                     /protein_id="NP_001386346.1"
                     /db_xref="GeneID:94267"
                     /db_xref="RGD:621355"
                     /translation="MKFKPNQTRTYDREGFKKRAACLCFRSEQEDEVLLVSSSRYPDQ
                     WIVPGGGVEPEEEPGGAAAREVYEEAGVKGKLGRLLGIFEQNQDRKHRTYVYVLTVTE
                     ILEDWEDSVNIGRKREWFKVEDAIKVLQCHKPVHAEYLERLKLGCSPTNGNSTVPSLP
                     DNNALFVTAAPPSGVPSSIR"
     exon            495..605
                     /gene="Nudt4"
                     /gene_synonym="DRCF-5"
                     /inference="alignment:Splign:2.1.0"
     exon            606..650
                     /gene="Nudt4"
                     /gene_synonym="DRCF-5"
                     /inference="alignment:Splign:2.1.0"
     exon            651..738
                     /gene="Nudt4"
                     /gene_synonym="DRCF-5"
                     /inference="alignment:Splign:2.1.0"
     exon            739..3217
                     /gene="Nudt4"
                     /gene_synonym="DRCF-5"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atccttggcg tctctgcccg gtttgcgccg ccgcttccaa ctgtctccgc gtggcacgag
       61 ccacgagccg cgctcttccc ccggcggcgg cggtggcggc ggcggcggcg ggtgcaagca
      121 aagagtggct gcaagcggct gcgggctcca tggagagcgg cgggcgcccg agcagaggcg
      181 gcgctaccac cgctgcgccc ggactgcagt gacccgcgtt ccgccccgcg tcccggcggc
      241 cgcccggcct cgccgtccgt gtccgcgccg ccgccgcctc ccgtcccacc ggctccggag
      301 caccgcgact tcgttcggtc cgactccccg gcggggtggc ggcggccggg tccccacggt
      361 ggcggccgga gcagcggctg caggagcccg gctctaggat gaagttcaag cccaaccaga
      421 cgcggacata cgaccgcgag ggcttcaaga agcgggcggc ctgcctgtgc ttccgcagcg
      481 agcaggagga cgaggtgctg ttggtgagca gcagtcggta cccagaccaa tggatcgtgc
      541 cgggaggagg ggtggagccg gaggaggagc ctggcggtgc tgctgcaagg gaagtgtatg
      601 aagaggctgg agtcaaagga aaattaggca gactcctggg aatatttgag cagaatcaag
      661 accggaagca cagaacatat gtttatgttc tgacagtcac tgaaatattg gaagactggg
      721 aagactctgt taacataggg aggaagagag agtggttcaa agtggaagac gcaatcaagg
      781 ttcttcagtg tcacaagcct gtccacgcag agtacctgga aaggctgaag ctggggtgtt
      841 ctccgaccaa tgggaattcc acagtccctt ccctcccaga taacaatgcc ttgtttgtga
      901 ctgccgcacc accctctggg gtgccatcca gtataagata gagagctggg gcccctcccc
      961 caccgtgtca tggcacatgt cagagggaga gaggcttttt tacttctaac acatctgact
     1021 gctgctggca gactctagat ttgccatgca ggggtttcaa ataatttgca tgtatttcag
     1081 atgctttcaa ctcttttaaa ataaataaca aaatagcaaa aatactttaa gatgccaaag
     1141 ccatgtggat tttttttaaa gccttaattg taagtctacc ccattacttt ggttctcatt
     1201 tttataacct ttcttaaaat ttcacttttg aacactcaac attctatggt ttattttgac
     1261 agatcaactg gttgttgggt atgtttttgc cctaatattt ttttcttaca gtatcaaata
     1321 gtcaccaaat ctttgggaat taattaatta atattcttgg tatttaaaaa aatatatata
     1381 tgtgccccaa aacttgttta agagagtcgc attctctcca cttgtaagct gcaggtttgc
     1441 gctgatttgt atggacgggc cagttgcctt tgaccaagca ctcaagttta ctctatccga
     1501 gaatttgtac acagcaagaa ttatgtcagt gcacaggcac tgcctcccct ctgacacggt
     1561 gattccatat gaatcactcc atttttaggg aaaactgtca ggaacttgcc tgtggcaccg
     1621 cacagctcat tctgaaactg ttcagagaag tctgttcagc acgctctgcg gctgcttcct
     1681 ccctgctcct tccgacacag actgtgttag gggccacatt gctcccatgg ccagtgctct
     1741 tcatattttc agtctagcaa caacattgtt gaccagtgga ttagactcta accttagata
     1801 cagcagtcac tgactggcat ccaaggttag atcacactaa acaaaatggc tgtcctaggc
     1861 ctaagacact gtcttgagtg tcagtaagca gcttgtcaga tgagtgtgag ggaactagaa
     1921 ctatgttacc ttgtctttgt gctctctcaa aacgggccac cccatggaaa agtacctaca
     1981 tttccttcag gaagtcatgg aggaagtgaa ggggtggggg gaggaaaaga tctttcgcag
     2041 tacagttagg acatctgtaa cctgttaacc tttaaattgt aatgttgctg ctgccaatgt
     2101 ccttacctgt aaggaaggaa aatgagatct cgtgccacaa atgcagcaga actaaaaaca
     2161 ttaggttaca aagcagaaaa acccaaccag tagtgttcat tctaaattat gtagcataaa
     2221 caaatgtgat cgtccagacc ttttctattt ttctttgtac agaggtcatg tactctgggt
     2281 gtgttttaaa agaaacattt taaagaaacc cacagattga cattttctat cttttcgttt
     2341 tctcacgatt ctctgcaatt tttccatgta ctaaacacaa cagaaactgg actgttttgt
     2401 atagaatact gcttccagct aaaaccatca caagtgcccg ggagtttatg tggacatgat
     2461 agatactctg ggcggtaata atgcatgaac ctgttttata aactcttgaa ctgtgtattg
     2521 ccatgtaaaa tatgtacagt attaatgtca accatctctt taaaagttag cctatgaaca
     2581 ttgttgtata atttctttgg tcagaaacat ttggactaag tcatgtcacc tgggtcagga
     2641 ttttcttcaa tgccgtgtag caaaactgtc tttagtctat gcaaatagcg agtcactgag
     2701 tgtgacagaa tgcaacttca ctgttaaact tcacctgagg gttcctcatt ctcctggaat
     2761 ccagactgca agattataaa ggaaaagacc taaggcaatt cagttctttt tgcaaatcaa
     2821 ttgaatccac gagagatgtc taccagcgag atgtctacca gcccagccgc ctgcagcctg
     2881 ctgtgtgtgc ttatttgtgc gctgaataaa atggggcagc taaattctcc agttccatat
     2941 gcctccgaag ttcaaagaaa aaaaagcaaa gtaacatgtt agacttgact tgtgtggcgg
     3001 cgtaaagaaa tggcatcttc ccactaagaa cgaaccatcc agttcttttg tcagtcacac
     3061 tatgaaacag ggaaggtgaa gggaagaaat ggttatgtgt gcacgaatcg ctttgcatgg
     3121 tctcatgaga tggctgcatt cgaactgttt taagaattgt aaggatcttg acttttttac
     3181 atttggaaac atcaaataaa aacaaacata atctgtg
//
