LOCUS       NM_001107825            2174 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus netrin G2 (Ntng2), mRNA.
ACCESSION   NM_001107825 XM_001076013 XM_001076031 XM_001076051 XM_001076071
            XM_242297
VERSION     NM_001107825.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2174)
  AUTHORS   Matsukawa,H., Akiyoshi-Nishimura,S., Zhang,Q., Lujan,R.,
            Yamaguchi,K., Goto,H., Yaguchi,K., Hashikawa,T., Sano,C.,
            Shigemoto,R., Nakashiba,T. and Itohara,S.
  TITLE     Netrin-G/NGL complexes encode functional synaptic diversification
  JOURNAL   J Neurosci 34 (47), 15779-15792 (2014)
   PUBMED   25411505
REFERENCE   2  (bases 1 to 2174)
  AUTHORS   Pan,Y., Liu,G., Fang,M., Shen,L., Wang,L., Han,Y., Shen,D. and
            Wang,X.
  TITLE     Abnormal expression of netrin-G2 in temporal lobe epilepsy neurons
            in humans and a rat model
  JOURNAL   Exp Neurol 224 (2), 340-346 (2010)
   PUBMED   20382146
  REMARK    GeneRIF: Netrin-g2 is involved in the pathophysiology of epilepsy
            and are consistent with the hypothesis that this protein may
            participate in the abnormal development of synapses and in neuron
            migration
REFERENCE   3  (bases 1 to 2174)
  AUTHORS   Kim,S., Burette,A., Chung,H.S., Kwon,S.K., Woo,J., Lee,H.W.,
            Kim,K., Kim,H., Weinberg,R.J. and Kim,E.
  TITLE     NGL family PSD-95-interacting adhesion molecules regulate
            excitatory synapse formation
  JOURNAL   Nat Neurosci 9 (10), 1294-1301 (2006)
   PUBMED   16980967
REFERENCE   4  (bases 1 to 2174)
  AUTHORS   Nakashiba,T., Nishimura,S., Ikeda,T. and Itohara,S.
  TITLE     Complementary expression and neurite outgrowth activity of netrin-G
            subfamily members
  JOURNAL   Mech Dev 111 (1-2), 47-60 (2002)
   PUBMED   11804778
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH474001.2.
            
            [WARNING] On Oct 24, 2024 this sequence was replaced by
            NM_001107825.2.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_001076051.1, XM_001076013.1, XM_001076031.1, XM_001076071.1,
            XM_242297.4.
            
            ##Evidence-Data-START##
            RNAseq introns :: mixed sample support SAMD00132282, SAMEA5756307
                              [ECO:0006172]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..2174
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="3"
                     /map="3p12"
     gene            1..2174
                     /gene="Ntng2"
                     /note="netrin G2"
                     /db_xref="GeneID:311836"
                     /db_xref="RGD:1307089"
     exon            1..447
                     /gene="Ntng2"
                     /inference="alignment:Splign:2.1.0"
     CDS             235..1929
                     /gene="Ntng2"
                     /codon_start=1
                     /product="netrin-G2 precursor"
                     /protein_id="NP_001101295.1"
                     /db_xref="GeneID:311836"
                     /db_xref="RGD:1307089"
                     /translation="MLHLLALFLHCLPLVSGDYDICKSWVTTDEGPTWEFYACQPKVM
                     RLKDYVKVKVEPSGITCGDPPERFCSHENPYLCSNECDASNPDLAHPPRLMFDREDEG
                     LATYWQSVTWSRYPSPLEANITLSWNKSVELTDDVVMTFEYGRPTVMVLEKSLDNGRT
                     WQPYQFYAEDCMEAFGMSARRARDMSPSSAHRVLCTEEYSRWAGSKKEKHVRFEVRDR
                     FAIFAGPDLRNMDNLYTRMESAKGLKEFFTFTDLRMRLLRPALGGTYVQRENLYKYFY
                     AISNIEVIGRCKCNLHANLCTVREGSLQCECEHNTTGPDCGKCKKNFRTRAWRAGSYL
                     PLPHGSPNACAAAGSAFGTVTIPVAIPSQAKDSTLFQLKPRSPQVIPIEEFQDCECYG
                     HSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNCNQIG
                     SVHDRCNETGFCECREGAVGPKCDDCLPTHYWRQGCYPNVCDDDQLLCQNGGTCQQNQ
                     RCACPPGYAGIRCEQPRCDLADDAGPDCDRAPGTVPRPDTLLGCLLLLGLAARLTC"
     exon            448..1091
                     /gene="Ntng2"
                     /inference="alignment:Splign:2.1.0"
     exon            1092..1264
                     /gene="Ntng2"
                     /inference="alignment:Splign:2.1.0"
     exon            1265..1291
                     /gene="Ntng2"
                     /inference="alignment:Splign:2.1.0"
     exon            1292..1393
                     /gene="Ntng2"
                     /inference="alignment:Splign:2.1.0"
     exon            1394..1561
                     /gene="Ntng2"
                     /inference="alignment:Splign:2.1.0"
     exon            1562..1696
                     /gene="Ntng2"
                     /inference="alignment:Splign:2.1.0"
     exon            1697..2174
                     /gene="Ntng2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ttgatctgcc catcagcagc ctgagaaacg ctggctctgg attttctgtc tcggccattt
       61 ggagaacgca aactcccccg ttggcaaacc agacctgcac tgtcgaatca atggtacagc
      121 ccagccgcca tcgcctggta gatgtggcat ttccatgctg aggtcccaag tgccccctga
      181 ccccaccacc tctccagtgc ccctctgggc cccacccatt cggactgcgc agccatgctg
      241 cacctgctgg ccctcttcct gcactgcctc ccgctggtct ctggggacta tgacatctgt
      301 aaatcctggg tgaccacaga tgagggcccc acctgggagt tctacgcttg ccagcccaag
      361 gtgatgcgct tgaaggatta tgtcaaggtc aaagtggagc cctcgggtat cacgtgtgga
      421 gatccccctg aaaggttctg ttcccatgag aacccttacc tgtgcagtaa cgagtgtgat
      481 gcctccaacc ctgacctggc ccacccaccc cggcttatgt ttgacaggga agatgaggga
      541 ctggccacct actggcaaag cgtcacgtgg agtcgctacc ccagtccact ggaagccaac
      601 atcaccctct catggaacaa gagcgtggag ttgacagacg atgtggtgat gactttcgag
      661 tatggccggc ccacggtcat ggtcctcgag aagtctctgg acaatggccg cacctggcag
      721 ccctaccagt tctatgcaga agactgcatg gaggccttcg gcatgtctgc ccgccgcgcc
      781 cgagacatgt caccctccag cgcccaccgg gtgctctgca ccgaggaata ctcacgctgg
      841 gcagggtcca agaaagagaa gcatgtgcgc tttgaggtaa gggaccgctt cgccatcttt
      901 gccggccctg acctgcgtaa catggacaac ctgtacacga ggatggagag cgccaagggc
      961 ctcaaggagt tcttcacctt cactgacctg cgcatgcgcc tgctgcgtcc tgcgctgggt
     1021 ggcacctacg tgcagcgaga gaacctctac aagtatttct acgccatctc caatatcgaa
     1081 gtcatcggca ggtgcaagtg caacctgcat gccaacctgt gcactgtgcg tgagggcagc
     1141 ctgcagtgtg agtgtgaaca caacaccaca ggtcctgact gtggcaagtg caagaagaac
     1201 ttccgcacgc gcgcctggcg agctggctcc tacctgccct tgccccacgg ctctcccaat
     1261 gcctgtgcag ccgcaggctc cgcctttggc actgtgacta tccctgtcgc catcccttcc
     1321 caagccaagg actctacact tttccagctc aagcccagat ctcctcaggt gatacccatt
     1381 gaagagtttc aagactgtga gtgctacggg cactccaacc gctgcagcta cattgacttc
     1441 ctgaacgtgg tgacctgtgt cagctgcaaa cacaacactc gaggccagca ctgtcagcac
     1501 tgccgcctgg gttactatcg caacggctct gccgagctgg atgacgagaa cgtctgcatc
     1561 gaatgtaact gtaaccagat cggctctgtg cacgatcgtt gcaacgagac aggcttctgc
     1621 gagtgcaggg agggcgcagt ggggcccaag tgcgacgact gccttcctac acactactgg
     1681 cgccaaggat gctaccccaa tgtgtgcgac gacgaccagc tgctctgcca gaacggcggc
     1741 acctgccagc agaaccagcg ctgcgcctgc ccgcctggct acgccggcat tcgctgcgag
     1801 cagccccgct gtgacctcgc cgacgacgct ggcccggact gtgaccgcgc gccaggcacc
     1861 gtcccgcgcc ccgacaccct gctcggatgc ctgctgctgc tcgggctggc cgcccgtctg
     1921 acctgctgag cccgttttag gggtccgggg gtcccgggcc cggcggcgat acgggtgcgg
     1981 ccgagctgct cccaggtgct actcgcagag tcctcctgcc ctccctgctc cgcccgctct
     2041 caccagcccc gcccggcact gccctcgccg gccacagggg gcgctgtgga gccctggctc
     2101 ggcggactgc gactttgagt ttttttatga cctaatgtct ctattttttt ctcatttttc
     2161 cattttccca tgtt
//
