LOCUS       NM_001025019            1278 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus N-terminal Xaa-Pro-Lys N-methyltransferase 1
            (Ntmt1), mRNA.
ACCESSION   NM_001025019
VERSION     NM_001025019.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1278)
  AUTHORS   Wu,R., Yue,Y., Zheng,X. and Li,H.
  TITLE     Molecular basis for histone N-terminal methylation by NRMT1
  JOURNAL   Genes Dev 29 (22), 2337-2342 (2015)
   PUBMED   26543159
REFERENCE   2  (bases 1 to 1278)
  AUTHORS   Tooley,C.E., Petkowski,J.J., Muratore-Schroeder,T.L.,
            Balsbaugh,J.L., Shabanowitz,J., Sabat,M., Minor,W., Hunt,D.F. and
            Macara,I.G.
  TITLE     NRMT is an alpha-N-methyltransferase that methylates RCC1 and
            retinoblastoma protein
  JOURNAL   Nature 466 (7310), 1125-1128 (2010)
   PUBMED   20668449
REFERENCE   3  (bases 1 to 1278)
  AUTHORS   Webb,K.J., Lipson,R.S., Al-Hadid,Q., Whitelegge,J.P. and
            Clarke,S.G.
  TITLE     Identification of protein N-terminal methyltransferases in yeast
            and humans
  JOURNAL   Biochemistry 49 (25), 5225-5235 (2010)
   PUBMED   20481588
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC091294.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC091294.1, DN933978.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on expression
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1278
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="3"
                     /map="3p12"
     gene            1..1278
                     /gene="Ntmt1"
                     /gene_synonym="Mettl11a; NTM1A; RGD1306582"
                     /note="N-terminal Xaa-Pro-Lys N-methyltransferase 1"
                     /db_xref="GeneID:362103"
                     /db_xref="RGD:1306582"
     exon            1..125
                     /gene="Ntmt1"
                     /gene_synonym="Mettl11a; NTM1A; RGD1306582"
                     /inference="alignment:Splign:2.1.0"
     exon            126..329
                     /gene="Ntmt1"
                     /gene_synonym="Mettl11a; NTM1A; RGD1306582"
                     /inference="alignment:Splign:2.1.0"
     CDS             168..839
                     /gene="Ntmt1"
                     /gene_synonym="Mettl11a; NTM1A; RGD1306582"
                     /EC_number="2.1.1.244"
                     /note="methyltransferase-like protein 11A; alpha
                     N-terminal protein methyltransferase 1A; X-Pro-Lys
                     N-terminal protein methyltransferase 1A; methyltransferase
                     like 11A"
                     /codon_start=1
                     /product="N-terminal Xaa-Pro-Lys N-methyltransferase 1"
                     /protein_id="NP_001020190.1"
                     /db_xref="GeneID:362103"
                     /db_xref="RGD:1306582"
                     /translation="MTSEVIEDEKQFYSKAKTYWKQIPPTVDGMLGGYGHISNIDLNS
                     SRKFLQRFLREGPNKTGTSCALDCGAGIGRITKRLLLPLFRVVDMVDVTEDFLAKAKT
                     YLGEEGKRVRNYFCCGLQDFSPEPSSYDVIWIQWVIGHLTDQHLAEFLRRCRRGLRPN
                     GIIVIKDNMAQEGVILDDVDSSVCRDLEVVRRIIRSAGLSLLAEERQENLPDEIYHVY
                     SFALR"
     exon            330..582
                     /gene="Ntmt1"
                     /gene_synonym="Mettl11a; NTM1A; RGD1306582"
                     /inference="alignment:Splign:2.1.0"
     exon            583..1254
                     /gene="Ntmt1"
                     /gene_synonym="Mettl11a; NTM1A; RGD1306582"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gacaaaggca gaggccgcga ggtgtctggt ccggtagagt ggtggcggca gccgtgggct
       61 acggtctttg ccagcctcct cctcaacccg tccttgtctt tcgagtccct ggagccacca
      121 cctaggggag cagagcagtg gctggtgact gtgcagctgg tgacgtcatg acaagcgagg
      181 tgatcgaaga tgagaaacag ttttattcga aggccaagac ctactggaag cagattccgc
      241 ccacggtgga cggcatgctc ggggggtatg gccacatctc caacatcgac ctcaacagct
      301 cccggaagtt tctgcagagg tttttaaggg aaggcccaaa caagacgggg acttcctgtg
      361 ccctggactg tggtgctggc attggaagga tcaccaagcg cctgctcctg ccgctcttca
      421 gggtggttga catggtcgac gtgacggaag actttctggc caaagccaag acctacctgg
      481 gggaagaggg caagagggtg aggaactact tctgctgtgg gctgcaggac ttcagccctg
      541 agcccagctc ctatgacgtg atctggatcc agtgggtgat aggccacctg acggatcagc
      601 acctggctga gtttctgcgc cgctgcaggc ggggcctgcg ccccaatggc atcattgtca
      661 tcaaagacaa catggcccag gagggtgtga tcctggacga tgtggacagc agtgtgtgcc
      721 gtgacctcga ggtggtccgc cggatcatcc gcagtgcagg cctcagcctc ctggctgagg
      781 agcgccagga gaacctgcca gatgagatct atcacgtcta cagtttcgcc ctgagatgaa
      841 accggggcca gagctggggg ccagcagctg gcaggccaag agacacctgc cacccaccaa
      901 tgactccagt gggaagggac aagccccaga gtaggtgtgc cctggattgg ggcagtgcag
      961 ccctgtcact ccaaagcacc ctggcgactc cctgcagggc ctacgggaag ctgagttgtc
     1021 cccactggac cagccgccta aggggaaaga cttcacttgg ttgcctagga cctgaagtgt
     1081 gtggactgct gtgttccagg acagccaggc aagccacaca tggtacccgc cagaaggtac
     1141 cacttacggg tatggtcaca gccccaaatc ctctttggtg atgggtcata gcagcctgta
     1201 gctcctccct gacaggcatg tgcagtcaat aaaagggtga gccttgttct caaaaaaaaa
     1261 aaaaaaaaaa aaaaaaaa
//
