LOCUS       NM_001025124            1087 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus N-terminal asparagine amidase (Ntan1), transcript
            variant 1, mRNA.
ACCESSION   NM_001025124
VERSION     NM_001025124.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1087)
  AUTHORS   Cantor,J.R., Stone,E.M. and Georgiou,G.
  TITLE     Expression and biochemical characterization of the human enzyme
            N-terminal asparagine amidohydrolase
  JOURNAL   Biochemistry 50 (14), 3025-3033 (2011)
   PUBMED   21375249
REFERENCE   2  (bases 1 to 1087)
  AUTHORS   Kwon,Y.T., Balogh,S.A., Davydov,I.V., Kashina,A.S., Yoon,J.K.,
            Xie,Y., Gaur,A., Hyde,L., Denenberg,V.H. and Varshavsky,A.
  TITLE     Altered activity, social behavior, and spatial memory in mice
            lacking the NTAN1p amidase and the asparagine branch of the N-end
            rule pathway
  JOURNAL   Mol Cell Biol 20 (11), 4135-4148 (2000)
   PUBMED   10805755
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC091175.1.
            
            On Mar 3, 2021 this sequence version replaced NM_001025124.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: FQ230577.1, FQ216165.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760434, SAMEA5760476
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1087              BC091175.1         5-1091
FEATURES             Location/Qualifiers
     source          1..1087
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="10"
                     /map="10q11"
     gene            1..1087
                     /gene="Ntan1"
                     /gene_synonym="RGD1305160"
                     /note="N-terminal asparagine amidase"
                     /db_xref="GeneID:360462"
                     /db_xref="RGD:1305160"
     exon            1..107
                     /gene="Ntan1"
                     /gene_synonym="RGD1305160"
                     /inference="alignment:Splign:2.1.0"
     CDS             27..956
                     /gene="Ntan1"
                     /gene_synonym="RGD1305160"
                     /EC_number="3.5.1.121"
                     /note="isoform 1 is encoded by transcript variant 1;
                     N-terminal Asn amidase; protein N-terminal asparagine
                     amidohydrolase"
                     /codon_start=1
                     /product="protein N-terminal asparagine amidohydrolase
                     isoform 1"
                     /protein_id="NP_001020295.1"
                     /db_xref="GeneID:360462"
                     /db_xref="RGD:1305160"
                     /translation="MPLLVDGRRVRLPLSATELVRAHPLLEERARLLRGQSVQQVGPQ
                     GLLYVQQRELAVTSPKDGSVSILGSDDATTCHIVVLRHTGNGATCLTHCDGSDTKAEV
                     PLIMNSIKSFSEHAECGRLEVHLVGGFSDDRQLSQKLTHQLLSEFDKQDDDIHLVTLC
                     VTELNDREENENHFPIIYGIAVNIKTAEIYRASFQDRGPEEQLRAARALAGGPMISIY
                     DAKTEQLRIGPCSWTPFPHVDFWLQQDDKQILENLSTSPLAEPPHFVDHIRSTLMFLK
                     KFPSPENILFPGNKALLYRKNKDGLWEKISPGN"
     exon            108..210
                     /gene="Ntan1"
                     /gene_synonym="RGD1305160"
                     /inference="alignment:Splign:2.1.0"
     exon            211..276
                     /gene="Ntan1"
                     /gene_synonym="RGD1305160"
                     /inference="alignment:Splign:2.1.0"
     exon            277..385
                     /gene="Ntan1"
                     /gene_synonym="RGD1305160"
                     /inference="alignment:Splign:2.1.0"
     exon            386..459
                     /gene="Ntan1"
                     /gene_synonym="RGD1305160"
                     /inference="alignment:Splign:2.1.0"
     exon            460..513
                     /gene="Ntan1"
                     /gene_synonym="RGD1305160"
                     /inference="alignment:Splign:2.1.0"
     exon            514..567
                     /gene="Ntan1"
                     /gene_synonym="RGD1305160"
                     /inference="alignment:Splign:2.1.0"
     exon            568..665
                     /gene="Ntan1"
                     /gene_synonym="RGD1305160"
                     /inference="alignment:Splign:2.1.0"
     exon            666..779
                     /gene="Ntan1"
                     /gene_synonym="RGD1305160"
                     /inference="alignment:Splign:2.1.0"
     exon            780..1087
                     /gene="Ntan1"
                     /gene_synonym="RGD1305160"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 acttcggtct ggcggcggcc taggcaatgc ctctgctggt ggacgggcgg cgcgtccgtc
       61 tgccactgtc ggctacggag ctggtccgag cgcacccgct tctggaggag agagccagac
      121 ttctcagagg tcagtctgtt caacaagtgg gaccccaggg ccttctgtat gttcagcaga
      181 gagagcttgc agtgacctcc ccaaaggatg gctccgtctc cattctgggt tctgatgatg
      241 ctaccacttg tcacattgtg gtcctgaggc acacaggaaa tggggcgacc tgcctgacac
      301 actgtgatgg atctgacacc aaagctgaag tccccttaat aatgaactcc ataaaatcct
      361 tctctgaaca tgccgagtgc ggaaggctgg aagtccacct tgtgggagga ttcagtgatg
      421 ataggcagtt gtcacagaaa cttacgcatc agcttcttag tgaatttgac aaacaggatg
      481 atgacattca cttagtgaca ttatgtgtaa cagaattaaa tgaccgggaa gaaaatgaaa
      541 atcactttcc aatcatttat ggcatcgcag tcaacattaa aactgcagag atttacagag
      601 cttcctttca agatcgtggc ccagaggagc aactgcgtgc tgcgagagct ttagcaggag
      661 gcccaatgat tagcatttat gatgcaaaga cagaacaact tcgaataggc ccgtgttcct
      721 ggacgccatt cccacatgtg gatttctggt tgcagcaaga tgacaagcaa atcctagaga
      781 acctttctac ttctcctctg gctgagcccc cccactttgt tgaccatatt agatctacct
      841 tgatgttttt aaaaaaattc ccatctccag agaatatact gtttcctgga aataaagctc
      901 tcctctacag aaaaaataaa gatggcttat gggaaaagat ctctccaggg aactaacatc
      961 agatctgggt taccgaagaa ttcacctttt ggcctgaaga gaccgttgct ggtttggaat
     1021 tcacacctgc gcacttttac ttcctccatc cttactgtct cccgaaataa agcctcattt
     1081 tggcaaa
//
