LOCUS       NM_001173527            1347 bp    mRNA    linear   ROD 20-MAR-2023
DEFINITION  Rattus norvegicus NSE3 homolog, SMC5-SMC6 complex component
            (Nsmce3), mRNA.
ACCESSION   NM_001173527 XM_219708
VERSION     NM_001173527.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1347)
  AUTHORS   van der Crabben,S.N., Hennus,M.P., McGregor,G.A., Ritter,D.I.,
            Nagamani,S.C., Wells,O.S., Harakalova,M., Chinn,I.K., Alt,A.,
            Vondrova,L., Hochstenbach,R., van Montfrans,J.M.,
            Terheggen-Lagro,S.W., van Lieshout,S., van Roosmalen,M.J.,
            Renkens,I., Duran,K., Nijman,I.J., Kloosterman,W.P., Hennekam,E.,
            Orange,J.S., van Hasselt,P.M., Wheeler,D.A., Palecek,J.J.,
            Lehmann,A.R., Oliver,A.W., Pearl,L.H., Plon,S.E., Murray,J.M. and
            van Haaften,G.
  TITLE     Destabilized SMC5/6 complex leads to chromosome breakage syndrome
            with severe lung disease
  JOURNAL   J Clin Invest 126 (8), 2881-2892 (2016)
   PUBMED   27427983
REFERENCE   2  (bases 1 to 1347)
  AUTHORS   Doyle JM, Gao J, Wang J, Yang M and Potts PR.
  TITLE     MAGE-RING protein complexes comprise a family of E3 ubiquitin
            ligases
  JOURNAL   Mol Cell 39 (6), 963-974 (2010)
   PUBMED   20864041
REFERENCE   3  (bases 1 to 1347)
  AUTHORS   Taylor EM, Copsey AC, Hudson JJ, Vidot S and Lehmann AR.
  TITLE     Identification of the proteins, including MAGEG1, that make up the
            human SMC5-6 protein complex
  JOURNAL   Mol Cell Biol 28 (4), 1197-1206 (2008)
   PUBMED   18086888
REFERENCE   4  (bases 1 to 1347)
  AUTHORS   Kuwako K, Taniura H and Yoshikawa K.
  TITLE     Necdin-related MAGE proteins differentially interact with the E2F1
            transcription factor and the p75 neurotrophin receptor
  JOURNAL   J Biol Chem 279 (3), 1703-1712 (2004)
   PUBMED   14593116
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC098730.1.
            
            On May 13, 2010 this sequence version replaced XM_219708.4.
            
            ##Evidence-Data-START##
            Transcript is intronless :: BC098730.1 [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1347              BC098730.1         1-1347
FEATURES             Location/Qualifiers
     source          1..1347
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q22"
     gene            1..1347
                     /gene="Nsmce3"
                     /gene_synonym="Ndnl2"
                     /note="NSE3 homolog, SMC5-SMC6 complex component"
                     /db_xref="GeneID:309259"
                     /db_xref="RGD:1309206"
     exon            1..1328
                     /gene="Nsmce3"
                     /gene_synonym="Ndnl2"
                     /inference="alignment:Splign:2.1.0"
     CDS             83..919
                     /gene="Nsmce3"
                     /gene_synonym="Ndnl2"
                     /note="melanoma-associated antigen G1; necdin-like 2"
                     /codon_start=1
                     /product="non-structural maintenance of chromosomes
                     element 3 homolog"
                     /protein_id="NP_001166998.1"
                     /db_xref="GeneID:309259"
                     /db_xref="RGD:1309206"
                     /translation="MLQKPRGRGRPSTQGDRERDWGGSGEEAPSTSRGAGGTSQGSRA
                     SLSAPTVGPRTQKQLELKVAELVQFLLIKDQKKIPIKRTDILKHVVGDYRDVYPNLLK
                     LAAERLQYVFGYKLVELEPKSHTYILINALEPVEEDAEVRGDQGTPTSGLLMIVLGLI
                     FMKGNTITETEVWDFLRRLGVYPTKKHLIFGDPKKLITEDFVRQRYLEYRRIPHTDPV
                     DYELQWGPRTNLETSKMKVLKFVAKVHNQDPKDWPAQYCEALADEESRARPAASGLAT
                     SS"
ORIGIN      
        1 cctagagctt ttcaggcgcg cttgtagaag attctggcgg ttactgctcc ttaacctggc
       61 ctgctctccg ccgaccggtg acatgctgca gaaaccgagg ggccgcggcc ggcccagcac
      121 tcagggtgat cgggagcggg actggggagg ctctggcgag gaagcgccga gcacgtcccg
      181 cggcgcgggc ggcacctctc agggctcccg cgcttccctg tcggccccca ccgtggggcc
      241 gcgcacacag aagcagctag agctgaaggt ggccgaactg gtgcagttcc tgctgattaa
      301 ggaccagaag aagatcccga tcaagcgcac cgacatcctg aagcacgtgg tgggagacta
      361 ccgggacgtg taccccaatc ttctgaagct ggccgccgag cgcctgcagt acgtgttcgg
      421 gtacaagctg gtggaactgg agcccaagag ccacacctac atcctcatca acgcgctgga
      481 gccggtggag gaggatgctg aggtgagagg cgatcagggt acacccacct cgggcctgct
      541 tatgatagtc ctcgggctta tcttcatgaa aggcaacacc atcaccgaga ctgaagtctg
      601 ggactttctc cgacggctcg gagtgtatcc cactaagaag catttaattt ttggcgaccc
      661 aaagaaactc attaccgaag actttgtgcg gcagcgctat ttggagtacc ggaggatacc
      721 ccacaccgat cctgtggact atgaactaca gtggggcccg cgaaccaacc tggaaaccag
      781 caagatgaaa gttcttaagt tcgtggccaa agtccataat caggacccca aagactggcc
      841 ggcacaatac tgcgaggctt tggcagatga ggagagtagg gccagacctg cagctagtgg
      901 tctagccaca tcctcttgaa ctattgagtt gaagtctgag ggactctaga gatccagtat
      961 aaaagaacag gagaaaggga gttggaggaa gtttaattct gctaggcgga aatgccttgt
     1021 agctttagga tgggttgctg gttttttgtt tttttgtttt tgtttttgtt ttgatttttg
     1081 ttacggtttg gagctttaaa ttttcattgc taaagacatg gaagaaagtt ttcatttcat
     1141 tgtctattgt ttaaagtgtt ttctagcttt ctaaacctaa ctgggaaatt gtagtatgat
     1201 ggcaaacata gtcaagaagg aacacttagg taaattgctt tgatgttcta gacaataaag
     1261 aaacagggta gctattatct taatgactag ttcatgggaa aaaataaaag tctttttaaa
     1321 attgaaaaaa aaaaaaaaaa aaaaaaa
//
