LOCUS       NM_001413650            1566 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus NS5A transactivated protein 4 (Ns5atp4),
            transcript variant 1, mRNA.
ACCESSION   NM_001413650
VERSION     NM_001413650.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1566)
  AUTHORS   Jeng,E.E., Bhadkamkar,V., Ibe,N.U., Gause,H., Jiang,L., Chan,J.,
            Jian,R., Jimenez-Morales,D., Stevenson,E., Krogan,N.J.,
            Swaney,D.L., Snyder,M.P., Mukherjee,S. and Bassik,M.C.
  TITLE     Systematic Identification of Host Cell Regulators of Legionella
            pneumophila Pathogenesis Using a Genome-wide CRISPR Screen
  JOURNAL   Cell Host Microbe 26 (4), 551-563 (2019)
   PUBMED   31540829
REFERENCE   2  (bases 1 to 1566)
  AUTHORS   Wilson,R., Geyer,S.H., Reissig,L., Rose,J., Szumska,D., Hardman,E.,
            Prin,F., McGuire,C., Ramirez-Solis,R., White,J., Galli,A.,
            Tudor,C., Tuck,E., Mazzeo,C.I., Smith,J.C., Robertson,E.,
            Adams,D.J., Mohun,T. and Weninger,W.J.
  TITLE     Highly variable penetrance of abnormal phenotypes in embryonic
            lethal knockout mice
  JOURNAL   Wellcome Open Res 1, 1 (2017)
   PUBMED   27996060
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000002.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC098673.1, FQ214790.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-188               JAXUCZ010000002.1  177792070-177792257
            189-290             JAXUCZ010000002.1  177792631-177792732
            291-408             JAXUCZ010000002.1  177797281-177797398
            409-462             JAXUCZ010000002.1  177798011-177798064
            463-629             JAXUCZ010000002.1  177800090-177800256
            630-688             JAXUCZ010000002.1  177800348-177800406
            689-1566            JAXUCZ010000002.1  177804066-177804943
FEATURES             Location/Qualifiers
     source          1..1566
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="2"
                     /map="2q34"
     gene            1..1566
                     /gene="Ns5atp4"
                     /note="NS5A transactivated protein 4"
                     /db_xref="GeneID:361985"
                     /db_xref="RGD:1359625"
     exon            1..188
                     /gene="Ns5atp4"
                     /inference="alignment:Splign:2.1.0"
     CDS             123..884
                     /gene="Ns5atp4"
                     /note="isoform 1 is encoded by transcript variant 1;
                     uncharacterized protein C1orf43 homolog; NS5A
                     transactivated protein 4 like 1; NS5A (hepatitis C virus)
                     transactivated protein 4 like 1"
                     /codon_start=1
                     /product="protein C1orf43 homolog isoform 1"
                     /protein_id="NP_001400579.1"
                     /db_xref="GeneID:361985"
                     /db_xref="RGD:1359625"
                     /translation="MASSSNWLSGVNVVLVMAYGSLVFVLLFIFVKRQIMRFAMKSRR
                     GPHVPVGHNAPKDLKEEIDIRLSRVQDIKYEPQLLADDDTRLLQLETQGSQSCYNYLY
                     RMKALDAIRASEIPFHAEGRHPCSLMGKNFRSYLLDLRNTSTPFKGVRKALIDTLLDG
                     YETARYGTGVFGQSEYLRYQEALSELATVVKARIGSSQRQHQSAAKDLTQSPEMSPTT
                     IQVTYLPSSQKSKRPKHFLELKSFKDNYNTLESTL"
     exon            189..290
                     /gene="Ns5atp4"
                     /inference="alignment:Splign:2.1.0"
     exon            291..408
                     /gene="Ns5atp4"
                     /inference="alignment:Splign:2.1.0"
     exon            409..462
                     /gene="Ns5atp4"
                     /inference="alignment:Splign:2.1.0"
     exon            463..629
                     /gene="Ns5atp4"
                     /inference="alignment:Splign:2.1.0"
     exon            630..688
                     /gene="Ns5atp4"
                     /inference="alignment:Splign:2.1.0"
     exon            689..1566
                     /gene="Ns5atp4"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 aaaaccaaat ggaaatggcc ggagagctcc agggcaccta ggttccctgg cttcggcttc
       61 ggctgggcta acgcgcgagt gtggtgggac tatcctagga ggtgttcctg gagagagagg
      121 cgatggcgtc aagtagtaac tggctgtccg gagtgaatgt cgttcttgtg atggcgtacg
      181 ggagcctggt attcgtattg ctgtttattt ttgtgaagag acaaatcatg cgctttgcaa
      241 tgaaatctag aaggggacct catgtccctg tgggacacaa tgccccgaag gacttaaaag
      301 aggaaattga tattcggcta tccagagttc aggacatcaa gtatgaaccg cagctccttg
      361 cagatgatga taccagacta ctacagctgg aaacccaggg gagtcaaagt tgctacaact
      421 atctgtacag gatgaaagct ctagatgcca tccgtgcctc tgagatccca tttcatgctg
      481 aaggccggca cccctgttct ttaatgggta agaatttccg ctcctacttg ctagatctgc
      541 gaaacactag cactcctttt aagggtgttc gaaaggccct cattgatacc ctcctggatg
      601 gatatgagac agctcgctat gggacagggg tctttggcca gagtgagtac ttgcgttatc
      661 aggaggcctt gagtgagctg gccactgtgg tcaaagcacg aattgggagc tctcagagac
      721 aacaccagtc agcagctaaa gacctaactc agtcgcctga aatgtcacca acaaccattc
      781 aggtcacgta tctgccctcc agtcagaaga gcaaacgccc taagcacttc ctcgaactga
      841 agagctttaa agacaactac aacacactgg agagcactct gtgatggatg gagagcactc
      901 tgtgacggag ctgcccacaa gccagctgca tggcgctcag gatatctggt tcagcagacc
      961 cagacttttg gctaaagcat tctgacagag cagtgtctaa aaggtcattc ccaacccttt
     1021 cttatattgg ctaagacctc agtctctccc aggagcaatt cttctggatt tgaattcaaa
     1081 cgtcattctt aacatttctg ttgaagcttc cttgaaatct ttgcttgatt tcggatgtca
     1141 ttcacctacc ctactcaacg ttgtttagtc ctaaagttgt aaattgagat gagggatctt
     1201 ccatgtcgac cccattgcac ccaactgaat agaagtattg aggtttagag catctcggat
     1261 ttgattggtg gaaaagtccg tcaggacctc atggggaaag gagattgaga acgtgggtag
     1321 gatgtcctct ggaattttgg tgctccatct aaaccaggtg tattgtgaca tgaccatgac
     1381 gttcctaagg tggaaggatc tatccccact gttacccact acttatgaca ggtaaaaagg
     1441 aatgttctgg tacttggcat aacctatgcc aagatgtgac agtgtaaaga agtgctttcc
     1501 ttgaatgtca gtgtattagt ctcagtttac aaagtactga ataaaactaa ctactacaaa
     1561 accatg
//
