LOCUS       NM_001100560            7911 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus nuclear receptor interacting protein 1 (Nrip1),
            mRNA.
ACCESSION   NM_001100560 XM_001067591 XM_221724
VERSION     NM_001100560.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 7911)
  AUTHORS   You,J., Yue,Z., Chen,S., Chen,Y., Lu,X., Zhang,X., Shen,P., Li,J.,
            Han,Q., Li,Z. and Liu,P.
  TITLE     Receptor-interacting Protein 140 represses Sirtuin 3 to facilitate
            hypertrophy, mitochondrial dysfunction and energy metabolic
            dysfunction in cardiomyocytes
  JOURNAL   Acta Physiol (Oxf) 220 (1), 58-71 (2017)
   PUBMED   27614093
  REMARK    GeneRIF: This study indicates that suppression of SIRT3 by RIP140
            facilitates the development of cardiomyocyte hypertrophy,
            mitochondrial dysfunction and energy metabolic dysfunction.
REFERENCE   2  (bases 1 to 7911)
  AUTHORS   Chen,Y., Chen,S., Yue,Z., Zhang,Y., Zhou,C., Cao,W., Chen,X.,
            Zhang,L. and Liu,P.
  TITLE     Receptor-interacting protein 140 overexpression impairs cardiac
            mitochondrial function and accelerates the transition to heart
            failure in chronically infarcted rats
  JOURNAL   Transl Res 180, 91-102 (2017)
   PUBMED   27639592
  REMARK    GeneRIF: RIP140 aggravates metabolic repression, mitochondrial
            malfunction, and further accelerates the transition to heart
            failure in response to myocardial infarction stress.
REFERENCE   3  (bases 1 to 7911)
  AUTHORS   Zhang,L., Chen,Y., Yue,Z., He,Y., Zou,J., Chen,S., Liu,M., Chen,X.,
            Liu,Z., Liu,X., Feng,X., Li,M. and Liu,P.
  TITLE     The p65 subunit of NF-kappaB involves in RIP140-mediated
            inflammatory and metabolic dysregulation in cardiomyocytes
  JOURNAL   Arch Biochem Biophys 554, 22-27 (2014)
   PUBMED   24823858
  REMARK    GeneRIF: overexpression of RIP140 induced proinflammatory gene
            expression and cytokine release in neonatal cardiomyocytes, which
            could be reversed by p65-NF-kappaB inhibition
REFERENCE   4  (bases 1 to 7911)
  AUTHORS   Constantinescu,S. and Turcotte,L.P.
  TITLE     Genetic downregulation of receptor-interacting protein 140 uncovers
            the central role of Akt signalling in the regulation of fatty acid
            oxidation in skeletal muscle cells
  JOURNAL   Exp Physiol 98 (2), 514-525 (2013)
   PUBMED   22923231
  REMARK    GeneRIF: In skeletal muscle cells, RIP140 expression significantly
            impacts palmitate uptake and oxidation and that alterations in gene
            expression and Akt-atypical protein kinaseC-theta signalling can
            partly explain these changes.
REFERENCE   5  (bases 1 to 7911)
  AUTHORS   Martyn,A.C., Choleris,E., Gillis,D.J., Armstrong,J.N., Amor,T.R.,
            McCluggage,A.R., Turner,P.V., Liang,G., Cai,K. and Lu,R.
  TITLE     Luman/CREB3 recruitment factor regulates glucocorticoid receptor
            activity and is essential for prolactin-mediated maternal instinct
  JOURNAL   Mol Cell Biol 32 (24), 5140-5150 (2012)
   PUBMED   23071095
REFERENCE   6  (bases 1 to 7911)
  AUTHORS   Wei,L.N., Hu,X., Chandra,D., Seto,E. and Farooqui,M.
  TITLE     Receptor-interacting protein 140 directly recruits histone
            deacetylases for gene silencing
  JOURNAL   J Biol Chem 275 (52), 40782-40787 (2000)
   PUBMED   11006275
REFERENCE   7  (bases 1 to 7911)
  AUTHORS   Lee,C.H. and Wei,L.N.
  TITLE     Characterization of receptor-interacting protein 140 in retinoid
            receptor activities
  JOURNAL   J Biol Chem 274 (44), 31320-31326 (1999)
   PUBMED   10531331
REFERENCE   8  (bases 1 to 7911)
  AUTHORS   Subramaniam,N., Treuter,E. and Okret,S.
  TITLE     Receptor interacting protein RIP140 inhibits both positive and
            negative gene regulation by glucocorticoids
  JOURNAL   J Biol Chem 274 (25), 18121-18127 (1999)
   PUBMED   10364267
REFERENCE   9  (bases 1 to 7911)
  AUTHORS   Lee,C.H., Chinpaisal,C. and Wei,L.N.
  TITLE     Cloning and characterization of mouse RIP140, a corepressor for
            nuclear orphan receptor TR2
  JOURNAL   Mol Cell Biol 18 (11), 6745-6755 (1998)
   PUBMED   9774688
REFERENCE   10 (bases 1 to 7911)
  AUTHORS   Cavailles,V., Dauvois,S., L'Horset,F., Lopez,G., Hoare,S.,
            Kushner,P.J. and Parker,M.G.
  TITLE     Nuclear factor RIP140 modulates transcriptional activation by the
            estrogen receptor
  JOURNAL   EMBO J 14 (15), 3741-3751 (1995)
   PUBMED   7641693
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000011.1.
            
            On Feb 10, 2021 this sequence version replaced NM_001100560.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence because no single transcript was available for the
            full length of the gene. The extent of this transcript is supported
            by transcript alignments and orthologous data.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643292.44937.1,
                                           SRR26643429.40406.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN12840129 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-178               JAXUCZ010000011.1  28466235-28466412   c
            179-253             JAXUCZ010000011.1  28445487-28445561   c
            254-372             JAXUCZ010000011.1  28425120-28425238   c
            373-7911            JAXUCZ010000011.1  28382835-28390373   c
FEATURES             Location/Qualifiers
     source          1..7911
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="11"
                     /map="11p11"
     gene            1..7911
                     /gene="Nrip1"
                     /gene_synonym="RIP140"
                     /note="nuclear receptor interacting protein 1"
                     /db_xref="GeneID:304157"
                     /db_xref="RGD:1311850"
     exon            1..178
                     /gene="Nrip1"
                     /gene_synonym="RIP140"
                     /inference="alignment:Splign:2.1.0"
     exon            179..253
                     /gene="Nrip1"
                     /gene_synonym="RIP140"
                     /inference="alignment:Splign:2.1.0"
     exon            254..372
                     /gene="Nrip1"
                     /gene_synonym="RIP140"
                     /inference="alignment:Splign:2.1.0"
     exon            373..7911
                     /gene="Nrip1"
                     /gene_synonym="RIP140"
                     /inference="alignment:Splign:2.1.0"
     CDS             708..4196
                     /gene="Nrip1"
                     /gene_synonym="RIP140"
                     /note="receptor-interacting protein 140"
                     /codon_start=1
                     /product="nuclear receptor-interacting protein 1"
                     /protein_id="NP_001094030.1"
                     /db_xref="GeneID:304157"
                     /db_xref="RGD:1311850"
                     /translation="MTHGEELGSDVHPDSIVLTYLEGLLMHQAAGGSGTAVDKKSAGH
                     SEEDQNFNLSGSAFPTCQSNGPTLSTQTYQGSGMLHLKKARLLQSSEDWNAAQRKRLS
                     DSIVNLNVKKEALLVGMVDSVPKGKQDSTVLASLLQSFSSRLQTVALSQQIRQSLKEQ
                     GYALSHESLKVEKDLRCYGVASSHLKTLLKKSKTKDQKSGTTLPDVTPNLIRDSFVES
                     SPHHVGQSGTKVMSEPLSCAARLQAVASMVEKRASPAASPKPSVACSQLALLLSSEAH
                     LQQYSREHALKTQSAHQAASERLAAMARLQENGQKDMSSFQLSKGVSGHLDGQARTLP
                     QSSKLAASKNNAAVFQNPMCGVPSSPKNTSYKNSLERNNIKQAANNSLLLHLLKSQTI
                     PTPMNGHSQHERGSSFESSTPTTIDEYSDNNPSFTDDSSGDESSYSNCVPIDLSCKHR
                     TEKPETERPVSLENLTQSLLNTWDPKVPGVDIKEDQDTSTNSKLNSHQKVTLLQLLLG
                     HKTEESVERNASPQEVHSDVTKFSPQNYTRTSVIESPSTNRTTPVSTPPLHTSSQGES
                     PINLSQHSLVIKWNSPPYACSTPASKLTNTVTGHLMDLTKGKESQAEKPAPSEGAQNS
                     ATFSASKLLQNLAQCGMQSSVPGEEQRPSKQLLSGHTDKPLGLIDRLNSPLLSNKANA
                     AEENKAFSSQPAGPEPGLPGCEIENLLERRTVLQLLLGNSNKGKSEKKERAPALDEAR
                     QEHSERPGNEQILMVKIKSEPCDDFQTHNTNVHLNHDAKSTPFLGGTPTIQRSSAALP
                     VSEDLKSEPASPQDFSFSKNGLLSRLLRQNQESYPADDQDKSHRNSELTPLESKNFCM
                     VPKKRKLYTEPLENPFKKMKNSAVDNANNHGGPEVLYGSLLNQEELKFSRNDLDYKYS
                     AGHSSASDGEHRSWARESKSFNVLKQLLLSENCVRDLSPHRSNSVTDNKKKGHKNNVP
                     NSKPEFSISSLNGLMYGSPQPGSCVDHRTFSYPGMVKTPLSSPFPEHLGCVGSRPEPG
                     LLNGCSVPVPGEKGPIKWVITDVEKNEYEKDSPRLTKTNPILYYMLQKGGNSVTTQET
                     QDKDIWGEPSSAESLSQVTVKEEMLPAAETKAAFFNLRSPYNSHMGNNASRPHSTNGE
                     AYGPLGNVLTIKKECE"
ORIGIN      
        1 agacattgca gcagagcccc gaactcggga ggcgacggcg accgcggcgc aggcggagga
       61 cgagccggcc ccagcccgcc ggtgcgcagc gcccgtggcc tcgcgcggcc gcagggcacg
      121 gctaacctgg gaaggaggga gcgacgcgga tcggcggccc ggagccgcgg cggcctcggt
      181 gtggagtgtg agcggtggca gagctgttct caggacccat tattttaacg tttgggagaa
      241 gcacatccta aaggtgcgca gtagactgag gtggacggga gaatctgaag actccggtga
      301 catcagagcc acttttcaac gaccttctca acttcctttc ccacatagca gaggctcagg
      361 gcgagacaga cgatactgtt ctgtgcgttt ggcgaagagc agaagatgaa gaaagaaaag
      421 gagtgtgttc cctaagacct gggtgccatg ccagcgctgc gctaaggaag ttgcgagact
      481 ggtccttgcg tagccggtaa tcagggctgt agtctgcatt ggagtttgcc tgcctcttag
      541 acgtcactgc cagaagatac cctggtcagg atgtaacagt gcttgtctgc ctgactgcca
      601 tgggaggtga ttgactgacg ctcgcttcct gaaggcggat cttaccgaca agaaaagcat
      661 ctttaaagtg aacagaagcc gagcccctgt aagcacttgt attgaacatg actcatggag
      721 aagagcttgg ctctgatgtg catccggatt ctattgtttt aacttaccta gaaggattac
      781 taatgcatca ggcagcaggg ggatcaggta ctgccgtcga caaaaagtct gctggccaca
      841 gcgaagaaga ccagaacttt aacctctctg gcagtgcctt tcccacctgt caaagcaatg
      901 gtcccactct cagtacacag acataccagg gatctggcat gctgcacctc aaaaaagcca
      961 gactgctgca gtcttctgag gactggaacg cggctcagcg gaagaggctg tccgattcca
     1021 tcgtgaattt aaacgtaaag aaggaggctt tgctggttgg catggttgac agtgtgccta
     1081 aaggcaaaca ggatagcaca gtactggcct ctttgctcca gtcattcagc tccaggctgc
     1141 agactgttgc tctgtcacag cagattagac agagcctcaa ggagcaagga tatgccctca
     1201 gccacgagtc gttgaaagtg gagaaggatt taaggtgcta cggcgtggcc tcaagtcact
     1261 taaaaactct gctgaagaaa agtaaaacta aggatcagaa gtcaggtacc accctccctg
     1321 atgtgactcc gaaccttatc agagatagct ttgttgagtc atcacctcat catgtcggac
     1381 aaagtggaac aaaggtcatg agtgagccct tgtcatgtgc tgcaagatta caggctgttg
     1441 ccagcatggt ggagaaaagg gctagtcccg ccgcctcccc caagcccagt gttgcctgca
     1501 gccagctagc gctgctcctt tccagtgagg cccacctgca gcagtactct cgggaacacg
     1561 ctctcaaaac acagagtgca catcaggcag caagtgaaag gctcgccgcc atggccagat
     1621 tgcaggagaa cggtcagaag gacatgagca gtttccagct ctctaagggg gtgtctggcc
     1681 atctcgacgg gcaggccaga acactgccac agtcaagcaa actggcggct agcaagaata
     1741 acgcagcagt ctttcagaat ccaatgtgcg gtgttccttc ctctcccaaa aacacaagct
     1801 ataagaactc tctggaaaga aacaacataa agcaagccgc taataacagt ttgcttttac
     1861 atcttctcaa aagccagacc atccccacgc cgatgaacgg gcacagccag cacgagagag
     1921 gaagtagttt tgagagtagc acacccacca cgatcgatga gtactctgat aacaatccta
     1981 gcttcacaga tgacagcagt ggggatgaaa gctcatactc caattgcgtt cccatagacc
     2041 tgtcctgcaa acaccggacc gagaaaccgg aaaccgagcg tcccgtttct cttgagaacc
     2101 taacccagtc cttgttaaac acgtgggatc ccaaagtgcc cggtgttgac atcaaagaag
     2161 atcaagatac ctcaacaaat tccaagctga attcacacca gaaagtcact cttcttcaat
     2221 tgctgcttgg ccataaaact gaggaaagtg ttgaaaggaa tgccagccct caggaagtcc
     2281 acagcgatgt gactaagttc agtcctcaga attacacaag gacttcagtc attgagagcc
     2341 ccagcaccaa caggactacc ccagtgagca ctccaccgct gcacacgtcc agtcaaggag
     2401 aatctcccat caatctttct caacactctc tggtcatcaa gtggaattcc ccgccatatg
     2461 cctgcagtac tcccgcttca aaactaacaa ataccgtgac tggccacctg atggacctca
     2521 caaaaggcaa agaatcacaa gcagagaaac cagccccgag tgaaggtgca caaaattcgg
     2581 cgacgttcag cgccagcaaa ctgttacaga atttggctca gtgcggaatg cagtcttccg
     2641 tgccagggga agagcagaga cccagcaaac agctgttaag tggacacaca gacaaacctc
     2701 tcggtctgat cgataggtta aatagccctc tgctctcaaa taaagcaaat gcagctgaag
     2761 aaaacaaagc cttcagcagt cagcctgcag ggcctgaacc aggacttcct ggttgtgaga
     2821 tagaaaacct actggaaaga cgcactgtcc ttcagttgct cctgggaaat tccaacaaag
     2881 ggaagagtga gaagaaagag agagctcccg cactggacga ggctcgtcag gagcattcgg
     2941 agagacccgg aaatgaacag atactgatgg tgaaaattaa atctgagccc tgtgatgact
     3001 tccagaccca caacacaaac gtgcatttaa accacgatgc caagagcacc ccgttcttag
     3061 gcgggactcc caccatccag aggagctcgg cggccttacc agtgtcagag gacttgaaat
     3121 cagagcctgc ttcacctcag gatttttctt tctcaaagaa cggtctgtta agtcgactgc
     3181 tgagacagaa tcaagagagt tacccagcag atgatcagga caagagtcac agaaacagtg
     3241 agctgacacc cctggaatcc aagaactttt gcatggtccc taaaaaaagg aagctttata
     3301 cggaaccact agaaaaccca tttaaaaaga tgaaaaatag tgccgtagat aatgccaata
     3361 atcatggtgg ccccgaagta ctctatgggt cgctgcttaa tcaggaggag ctgaaattta
     3421 gcagaaatga tctcgactat aaatactctg ctggtcacag ttcagccagc gatggtgaac
     3481 ataggagttg ggccagagag agcaaaagct tcaacgttct taagcagctg cttctctcag
     3541 agaactgtgt gcgagatttg tccccacaca ggagtaactc tgtcaccgac aataaaaaga
     3601 aaggacacaa aaacaacgtg cccaatagca aacctgaatt cagcatttct tctttaaatg
     3661 gactgatgta tggttcccct cagcctggca gttgtgtgga tcataggaca ttttcatacc
     3721 caggaatggt aaaaacccct ctgagctctc ctttcccaga gcacttgggc tgtgtagggt
     3781 ccaggccaga acctgggctt ttgaatggct gttctgtgcc cgtgcccggt gagaagggac
     3841 ccattaagtg ggtcatcaca gatgtggaga agaatgagta tgaaaaagac tctccgagac
     3901 tgaccaaaac caacccaatc ctctattaca tgctccagaa aggaggcaac tctgttacca
     3961 cacaagaaac acaggacaaa gacatctggg gggagccttc atctgccgag agtctctcac
     4021 aggttacagt caaggaagag atgcttcctg ccgcagaaac taaagctgct ttcttcaatc
     4081 tcagaagccc ttacaacagc catatgggaa ataatgcttc ccgcccgcac agtacaaacg
     4141 gagaagcgta tggacccctg ggaaacgtgc tcaccataaa aaaagagtgc gagtgaaggt
     4201 gtacctgcca tgtcatttgg gatcttttta gaactgatcg gtgtgaactt gagacccgta
     4261 tagataagag catgatttga gaaaagcatg ctgtaatcga aactccttcc ttttgaaagt
     4321 atcggtcact ggtgatgttt aaatatgcac actcatttcc gcttaacatt agatgtcatg
     4381 gggaagctag aggtttggtt gtttagtatt tctgtatgca tcagatgaca actgtgacta
     4441 gcctacgaat gaacctgttt tataactgta aacattaaaa tgcacaactt caccagtagt
     4501 ggattgatgc aacttgctgt ctttattggg gtctctcatt tcctatctca gaagccagtc
     4561 tacacaacat gtttgtaaca tgcacattgt tagctatttg gaagacaacc aaattaggaa
     4621 aaacccagaa gcctcgtgct gattcacacc tcatccgtct aaaagtaaga aaaggcaatg
     4681 cttacatttt tcacttttgc tagacaaaat tctttttaac tcttggaagg gtttttgcgc
     4741 ttcccaatgt gtctgccccg ccccagacct tttcaatatc gatttcttta aaccttgtac
     4801 tatttagtaa caattgatta caatagaggg gagtttacta gatccttaaa aataaaaggc
     4861 gatttccatt ttttaaatat tttgactact ttactaaatt aatactcctc ctttttcaaa
     4921 attcgagaag gtaatgctca ccttcgggca gtttcctgaa taattgacta cttagaaatc
     4981 atttttaaca aaagcagaaa tgggttttct cgggatggtt ttcaccatct cttttgaaag
     5041 ttaatcctca ccactcctgt gggacctgta acccttacaa ccagggtttc ttcattctgg
     5101 acacagaacc tgcattcgta ccatctgact atttggagaa gttgtttaac atgcagattc
     5161 ataggcagcc tctcaggtct acagaacagg gtctctgagt ggacccagga gtcttccttc
     5221 tgcctgaatc ctgacgtgtt ctgtatgtgt ttcttctgca cactgatgtt tgaaaactgt
     5281 ggcttaatga cttttccaga acatggaact ttaaagaaac tatttgatgc ctatattttc
     5341 ccccaataca gtcacatatc cactcaaaat ttgcaatatc gtagttccta tattgctgtt
     5401 atatctttgg aaatcgggtt cagaatactt tttatgacaa aaaaaaattg ggtagagggg
     5461 acaactttcc tatctgggtc aacatctcag gaaaatctgt gattatttat ttgctctaat
     5521 tagtaagatt aacttaatta gccttagggg tggaataaca gggccactta gcaaactcag
     5581 gtgatcccag gatggttggg aaacctctct tgaatacacc cttaccttct attcaagctg
     5641 tcctctgcac tgcagtgctt atggagctaa gagattcaac ccaagaaaga catcaaactc
     5701 tgattccctg aaaccaaatc aaagggcact tacctatcca tgacaggacc ttcacagtcc
     5761 cttcacggat cggttcattt taagcaggta tcacaactaa acactgatac tgtcttgaaa
     5821 gaacttaata gagagttgag ccacgtggaa tttcagtctc gaaacaagtt agattttaag
     5881 ttccattttt atagtccaca gttcatccac cagacaatat tttgtttttc aattttgagc
     5941 caggttaaca attaattgac ttgtggaaaa attattgggt cctcagccgt tacgtaggaa
     6001 gaagcttatt tgaagttgtc gtacgtactt gaagttgttt ctaagatttt tttttatatt
     6061 acaaatggac attgtttctt aattatctaa aattctaaat ggttattttt ttctcaagat
     6121 gatttgtaaa tagctaatgg atctgttgta tggtaatcag agtgtatatt atgctacgtc
     6181 agagaaagga gaaggcgtat gcttcttctg ctatgaaaaa ttccactggc cagtgaagat
     6241 tctttactcc atgtttatac tgtgacaatc tcattgtcta cactatataa ataagcttta
     6301 cactaagtca ttttttcttg gtcatggtga aagggctgga gccttagaaa tctatcgtgg
     6361 gatgctggtg tcctcagttg gaggcagtcg tcttacaatg caacagcact taggtcaggg
     6421 aaaatgtcca gggccagcat cgctatgctt tgttttgttt catttctgtt ggaatgagaa
     6481 tatgtaatgc aaaaataaac aggactataa agaatgttgt tctgacttac tagagaatat
     6541 ccctcatgtt ttgtttagag aaatcttaaa gaagagaaag ggcatacatc cacaaattca
     6601 ctgtgtgtgc atatgtaggt tcacatatgc acagacacag tttcaaggac tgttttcgat
     6661 atgtgggcag tttcttccta ataaagtcat ctgtgaatgg gtaccacagc tctcattgac
     6721 atcagtaagg tagcattacc tgtttattct ctgccacatc ttacagaaga ataaactggt
     6781 gagagtatat attttatata tatatataaa tgtgtatata tatatatatt gacttgttac
     6841 atgaagatgt taaaattggt ttttaaaggt gatgtaaata atgatttcct taatgaaaaa
     6901 aatacatatt ttgtattgtt ctaatgcaac agaaaaacct tttaatttct ttggttcctg
     6961 tatattccat gtattaagtg taaatataat cagacaggtt taaaaacatg tgcatgtatg
     7021 tatacagttg caagtctgga caaatgtata aaataaacct tttatttaag tttgattacc
     7081 tgctgcatga caagtgcatg ggaaaccctg tgcatccgtg catttgacag aaaatgtctt
     7141 aagtcagatc agatggtcgt ccacaaacga cagtattcca tttctggaca tgacctctgc
     7201 ggcttatgat ttgtgagaaa atgtgctttg aatccaaggg tcttgttttt ttctttttaa
     7261 tcaaccactt tcaacataaa gaactcacat agcgacttca caaatcgtaa aatcccactg
     7321 aaaacataac caggaacagt tcattgttcc taaatgctgg agtacaggca cattaccatt
     7381 catggtaaga gtcttggggt ttacagccag ttttgatgca atctgcttag tgatataatt
     7441 tgccattttt attattaaaa tttgatttct ttatgtgatg tcatgaattg tacatactac
     7501 agtgtgaatt tttttttgtt ttttttttta aatcctttag tgtttacttc ctgcagtgaa
     7561 ttgaataaat gagaaaaaat gcattgtctc taactttgaa acgacttatt tttgtgggct
     7621 ttctctggtt tttaggtttt tccattaatg ttaaagttca aggtcataaa gagaaaaggg
     7681 aaaagcaata gatcatgtat tttgtctgtt tcagaaaaat gaaaggggga gaaagaagca
     7741 actgaccagc aagttagtat atttagaaac gtgtaattaa agcatagctc aacatgacag
     7801 ctggcctgtg gtctgtcttc catttctcag tatgtaactg aatgaccact acatgttttt
     7861 tttaaactgg agtttgtaca gtgttccaaa ataaagttaa ttagatatat a
//
