LOCUS       NM_001136151            6158 bp    mRNA    linear   ROD 07-FEB-2025
DEFINITION  Rattus norvegicus neuregulin 2 (Nrg2), mRNA.
ACCESSION   NM_001136151 XM_001053475 XM_001063076 XM_344662
VERSION     NM_001136151.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 6158)
  AUTHORS   Vullhorst,D. and Buonanno,A.
  TITLE     NMDA Receptors Regulate Neuregulin 2 Binding to ER-PM Junctions and
            Ectodomain Release by ADAM10 [corrected]
  JOURNAL   Mol Neurobiol 56 (12), 8345-8363 (2019)
   PUBMED   31240601
  REMARK    GeneRIF: NRG2 and Kv2.1 are co-regulated components of a shared
            pathway that responds to elevated extracellular glutamate levels.
            Erratum:[Mol Neurobiol. 2020 Jan;57(1):585. doi:
            10.1007/s12035-019-01778-4.. PMID: 31522381]
REFERENCE   2  (bases 1 to 6158)
  AUTHORS   Nakano,N., Kanekiyo,K., Nakagawa,T., Asahi,M. and Ide,C.
  TITLE     NTAK/neuregulin-2 secreted by astrocytes promotes survival and
            neurite outgrowth of neurons via ErbB3
  JOURNAL   Neurosci Lett 622, 88-94 (2016)
   PUBMED   27113200
  REMARK    GeneRIF: NTAK/NRG2 secreted from astrocytes bound to ErbB3 on
            neurons, and promoted neuronal survival and neurite extension in
            vitro.
REFERENCE   3  (bases 1 to 6158)
  AUTHORS   Lee,K.H., Lee,H., Yang,C.H., Ko,J.S., Park,C.H., Woo,R.S.,
            Kim,J.Y., Sun,W., Kim,J.H., Ho,W.K. and Lee,S.H.
  TITLE     Bidirectional Signaling of Neuregulin-2 Mediates Formation of
            GABAergic Synapses and Maturation of Glutamatergic Synapses in
            Newborn Granule Cells of Postnatal Hippocampus
  JOURNAL   J Neurosci 35 (50), 16479-16493 (2015)
   PUBMED   26674872
  REMARK    GeneRIF: These results imply that NRG2 may play a critical role in
            network integration of newborn neurons
REFERENCE   4  (bases 1 to 6158)
  AUTHORS   Vullhorst,D., Mitchell,R.M., Keating,C., Roychowdhury,S.,
            Karavanova,I., Tao-Cheng,J.H. and Buonanno,A.
  TITLE     A negative feedback loop controls NMDA receptor function in
            cortical interneurons via neuregulin 2/ErbB4 signalling
  JOURNAL   Nat Commun 6, 7222 (2015)
   PUBMED   26027736
  REMARK    GeneRIF: Findings reveal an intimate reciprocal relationship
            between ErbB4 and GluN2b NMDA receptors via NRG2/ErbB4 signaling.
            Publication Status: Online-Only
REFERENCE   5  (bases 1 to 6158)
  AUTHORS   Mitchell,R.M., Janssen,M.J., Karavanova,I., Vullhorst,D., Furth,K.,
            Makusky,A., Markey,S.P. and Buonanno,A.
  TITLE     ErbB4 reduces synaptic GABAA currents independent of its receptor
            tyrosine kinase activity
  JOURNAL   Proc Natl Acad Sci U S A 110 (48), 19603-19608 (2013)
   PUBMED   24218551
REFERENCE   6  (bases 1 to 6158)
  AUTHORS   Longart,M., Liu,Y., Karavanova,I. and Buonanno,A.
  TITLE     Neuregulin-2 is developmentally regulated and targeted to dendrites
            of central neurons
  JOURNAL   J Comp Neurol 472 (2), 156-172 (2004)
   PUBMED   15048684
  REMARK    GeneRIF: In neuronal primary cultures from developing rat
            hippocampus, neuregulin 2 (NRG-2) is restricted to neuronal somas
            and dendrites.
REFERENCE   7  (bases 1 to 6158)
  AUTHORS   Hobbs,S.S., Coffing,S.L., Le,A.T., Cameron,E.M., Williams,E.E.,
            Andrew,M., Blommel,E.N., Hammer,R.P., Chang,H. and Riese,D.J. 2nd.
  TITLE     Neuregulin isoforms exhibit distinct patterns of ErbB family
            receptor activation
  JOURNAL   Oncogene 21 (55), 8442-8452 (2002)
   PUBMED   12466964
REFERENCE   8  (bases 1 to 6158)
  AUTHORS   Pinkas-Kramarski,R., Shelly,M., Guarino,B.C., Wang,L.M., Lyass,L.,
            Alroy,I., Alimandi,M., Kuo,A., Moyer,J.D., Lavi,S., Eisenstein,M.,
            Ratzkin,B.J., Seger,R., Bacus,S.S., Pierce,J.H., Andrews,G.C. and
            Yarden,Y.
  TITLE     ErbB tyrosine kinases and the two neuregulin families constitute a
            ligand-receptor network
  JOURNAL   Mol Cell Biol 18 (10), 6090-6101 (1998)
   PUBMED   9742126
  REMARK    Erratum:[Mol Cell Biol 1998 Dec;18(12):7602. Alamandi M [corrected
            to Alimandi M]]
REFERENCE   9  (bases 1 to 6158)
  AUTHORS   Higashiyama,S., Horikawa,M., Yamada,K., Ichino,N., Nakano,N.,
            Nakagawa,T., Miyagawa,J., Matsushita,N., Nagatsu,T., Taniguchi,N.
            and Ishiguro,H.
  TITLE     A novel brain-derived member of the epidermal growth factor family
            that interacts with ErbB3 and ErbB4
  JOURNAL   J Biochem 122 (3), 675-680 (1997)
   PUBMED   9348101
REFERENCE   10 (bases 1 to 6158)
  AUTHORS   Chang,H., Riese,D.J. 2nd, Gilbert,W., Stern,D.F. and McMahan,U.J.
  TITLE     Ligands for ErbB-family receptors encoded by a neuregulin-like gene
  JOURNAL   Nature 387 (6632), 509-512 (1997)
   PUBMED   9168114
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000018.1.
            
            On Mar 11, 2021 this sequence version replaced NM_001136151.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643295.56039.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760386 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-968               JAXUCZ010000018.1  28071571-28072538   c
            969-1140            JAXUCZ010000018.1  27928855-27929026   c
            1141-1259           JAXUCZ010000018.1  27922260-27922378   c
            1260-1380           JAXUCZ010000018.1  27914493-27914613   c
            1381-1457           JAXUCZ010000018.1  27908755-27908831   c
            1458-1560           JAXUCZ010000018.1  27900523-27900625   c
            1561-1684           JAXUCZ010000018.1  27898542-27898665   c
            1685-1812           JAXUCZ010000018.1  27898104-27898231   c
            1813-2040           JAXUCZ010000018.1  27897326-27897553   c
            2041-6158           JAXUCZ010000018.1  27890578-27894695   c
FEATURES             Location/Qualifiers
     source          1..6158
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="18"
                     /map="18p11"
     gene            1..6158
                     /gene="Nrg2"
                     /gene_synonym="Ntak; NTAK alpha1; NTAK alpha2a;
                     NTAK_alpha2a"
                     /note="neuregulin 2"
                     /db_xref="GeneID:432361"
                     /db_xref="RGD:1303302"
     exon            1..968
                     /gene="Nrg2"
                     /gene_synonym="Ntak; NTAK alpha1; NTAK alpha2a;
                     NTAK_alpha2a"
                     /inference="alignment:Splign:2.1.0"
     CDS             221..2803
                     /gene="Nrg2"
                     /gene_synonym="Ntak; NTAK alpha1; NTAK alpha2a;
                     NTAK_alpha2a"
                     /note="pro-NRG2; neural- and thymus-derived activator for
                     ErbB kinases"
                     /codon_start=1
                     /product="pro-neuregulin-2, membrane-bound isoform"
                     /protein_id="NP_001129623.2"
                     /db_xref="GeneID:432361"
                     /db_xref="RGD:1303302"
                     /translation="MRQVCCSALPPPLEKARCSSYSYSDSSSSSSSNNSSSSTSSRSS
                     SRSSSRSSRGSTTTTSSSENSGSNSGSIFRPAAPPEPRPQPQPQPRSPAARRAAARSR
                     AAAAGGMRRDPAPGFSMLLFGVSLACYSPSLKSVQDQAYKAPVVVEGKVQGLAPAGGS
                     SSNSTREPPASGRVALVKVLDKWPLRSGGLQREQVISVGSCAPLERNQRYIFFLEPTE
                     QPLVFKTAFAPVDPNGKNIKKEVGKILCTDCATRPKLKKMKSQTGEVGEKQSLKCEAA
                     AGNPQPSYRWFKDGKELNRSRDIRIKYGNGRKNSRLQFNKVKVEDAGEYVCEAENILG
                     KDTVRGRLHVNSVSTTLSSWSGHARKCNETAKSYCVNGGVCYYIEGINQLSCKCPNGF
                     FGQRCLEKLPLRLYMPDPKQKAEELYQKRVLTITGICVALLVVGIVCVVAYCKTKKQR
                     RQMHHHLRQNMCPAHQNRSLANGPSHPRLDPEEIQMADYISKNVPATDHVIRREAETT
                     FSGSHSCSPSHHCSTATPTSSHRHESHTWSLERSESLTSDSQSGIMLSSVGTSKCNSP
                     ACVEARARRAAAYSQEERRRAAMPPYHDSIDSLRDSPHSERYVSALTTPARLSPVDFH
                     YSLATQVPTFEITSPNSAHAVSLPPAAPISYRLAEQQPLLRHPAPPGPGPGPGADMQR
                     SYDSYYYPAAGPGPRRGACALGGSLGSLPASPFRIPEDDEYETTQECAPPPPPRPRTR
                     GASRRTSAGPRRWRRSRLNGLAAQRARAARDSLSLSSGSGCGSASASDDDADDADGAL
                     AAESTPFLGLRAAHDALRSDSPPLCPAADSRTYYSLDSHSTRASSRHSRGPPTRAKQD
                     SGPL"
     exon            969..1140
                     /gene="Nrg2"
                     /gene_synonym="Ntak; NTAK alpha1; NTAK alpha2a;
                     NTAK_alpha2a"
                     /inference="alignment:Splign:2.1.0"
     exon            1141..1259
                     /gene="Nrg2"
                     /gene_synonym="Ntak; NTAK alpha1; NTAK alpha2a;
                     NTAK_alpha2a"
                     /inference="alignment:Splign:2.1.0"
     exon            1260..1380
                     /gene="Nrg2"
                     /gene_synonym="Ntak; NTAK alpha1; NTAK alpha2a;
                     NTAK_alpha2a"
                     /inference="alignment:Splign:2.1.0"
     exon            1381..1457
                     /gene="Nrg2"
                     /gene_synonym="Ntak; NTAK alpha1; NTAK alpha2a;
                     NTAK_alpha2a"
                     /inference="alignment:Splign:2.1.0"
     exon            1458..1560
                     /gene="Nrg2"
                     /gene_synonym="Ntak; NTAK alpha1; NTAK alpha2a;
                     NTAK_alpha2a"
                     /inference="alignment:Splign:2.1.0"
     exon            1561..1684
                     /gene="Nrg2"
                     /gene_synonym="Ntak; NTAK alpha1; NTAK alpha2a;
                     NTAK_alpha2a"
                     /inference="alignment:Splign:2.1.0"
     exon            1685..1812
                     /gene="Nrg2"
                     /gene_synonym="Ntak; NTAK alpha1; NTAK alpha2a;
                     NTAK_alpha2a"
                     /inference="alignment:Splign:2.1.0"
     exon            1813..2040
                     /gene="Nrg2"
                     /gene_synonym="Ntak; NTAK alpha1; NTAK alpha2a;
                     NTAK_alpha2a"
                     /inference="alignment:Splign:2.1.0"
     exon            2041..6158
                     /gene="Nrg2"
                     /gene_synonym="Ntak; NTAK alpha1; NTAK alpha2a;
                     NTAK_alpha2a"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agtcctggcg cacagggagg gagcgctgcg ctgcgccggg gctgcgcatc gcggcccact
       61 tgccgcttgt cccctgccct ggctgggcca cctccccggg ctgccggtgg agggcttcga
      121 ggcgctaacg ttacgctgtt tccggttttc cagagggctc tgtttcccct cccaaggcgg
      181 cggcggctga gcggcggagc cccccaaatg gcctggccag atgcggcagg tttgctgctc
      241 agcgctgccg ccgccactgg agaaggctcg gtgcagcagc tacagctaca gcgacagcag
      301 cagcagcagc agcagcaaca acagcagcag cagcaccagc agcagaagca gcagcagaag
      361 cagcagcaga agcagcagag gcagcaccac caccaccagc agcagcgaga acagcggcag
      421 caacagcggc agcatcttcc gtcccgctgc gcccccagag ccgcggccgc agccacagcc
      481 gcagccccgc agccccgcag cccggagagc cgccgcccgc tcgcgagccg cagccgccgg
      541 cggcatgagg cgcgacccgg cccccggctt ctcgatgctg ctcttcggtg tgtcactcgc
      601 ctgctactcg cccagcctca agtccgtgca ggaccaggcg tacaaggcac ccgtggtggt
      661 ggagggcaag gtacagggac tggccccggc aggcggttcc agctctaaca gcacccgaga
      721 gcctcccgcc tcgggtcggg tggcgctggt gaaggtgctg gacaagtggc cgctccggag
      781 cggggggctg cagcgcgagc aggtgatcag cgtgggctcc tgcgcgccgc tcgaaaggaa
      841 ccagcgctac atctttttcc tggagcccac cgagcagccc ttagttttta agacagcctt
      901 tgccccggtc gaccctaacg gcaaaaacat caagaaagag gtgggcaaga tcctgtgcac
      961 tgactgcgca acccggccca agctgaagaa gatgaagagt cagacaggag aggtgggcga
     1021 gaagcagtcg ctcaagtgtg aggcggcggc ggggaacccc cagccctcct atcgatggtt
     1081 caaggacggc aaggagctca accggagtcg tgacattcgc atcaagtatg gcaacggcag
     1141 aaagaactca cggctacagt tcaacaaagt gaaggtggag gacgctggag agtacgtctg
     1201 tgaggctgag aacatccttg ggaaggacac tgtgaggggc cggctccatg tcaacagtgt
     1261 gagcaccact ctgtcgtcct ggtcggggca cgcccggaag tgcaatgaga cagccaagtc
     1321 ctactgtgtg aatggaggcg tgtgctacta catcgaaggc atcaaccaac tctcctgcaa
     1381 atgtccaaac ggattcttcg gacagagatg tttggagaaa ctgcctttgc gattgtacat
     1441 gccagatcct aagcaaaagg ctgaggagct gtaccagaag agagtcctga caattaccgg
     1501 catctgtgtg gctctgctgg tcgtgggcat cgtctgtgtg gtcgcctact gcaagactaa
     1561 aaaacagagg aggcaaatgc atcaccatct ccggcagaac atgtgtccgg cccaccagaa
     1621 ccgaagcctg gccaatgggc ccagccaccc tcggctggac cctgaggaga tccagatggc
     1681 agattacatt tccaaaaatg tgccagctac agaccatgtg atccggaggg aagctgagac
     1741 cacattttct gggagccact cctgttcacc ctctcaccac tgttccacag ccacacccac
     1801 ctccagccac agacatgaga gccacacgtg gagcttggaa cgttcggaga gcctgacctc
     1861 ggattcccag tcaggcatca tgctatcatc agtgggcacc agcaagtgca acagcccagc
     1921 atgtgtggag gcacgggcac ggagggcagc agcctacagc caggaggagc gacgcagggc
     1981 tgccatgcca ccctaccacg actccataga ctcgctgcgt gactccccac acagtgagag
     2041 gtacgtgtca gccctgacca cgcccgcgcg cctttcgccc gtggacttcc actactcgct
     2101 ggccacccag gtgccgactt tcgagatcac gtcgcccaac tctgcccacg ccgtgtcgct
     2161 gccacccgca gcgcccatca gctaccgcct agcggagcag cagccgctcc tgcggcaccc
     2221 agcgccgccc ggcccggggc cagggcccgg agcggacatg cagcgcagct acgacagcta
     2281 ctactacccg gcggcggggc ccgggccgcg gcgcggcgcc tgcgcgctgg gaggcagttt
     2341 gggcagcctg cccgccagcc ccttccgcat cccggaggac gacgagtacg agaccacgca
     2401 ggagtgcgcg cccccgccac cgccgcggcc gcgcacgcgc ggcgcgtccc gcaggacgtc
     2461 ggcggggccg cggcgctggc ggcgctcccg cctcaacggg ttggctgcgc agcgcgcacg
     2521 cgcagcgcgg gactcgctgt cgttgagcag cggttcgggc tgcggctcgg cgtcggcctc
     2581 ggacgacgat gcggacgacg cggacggggc gctggcggcc gagagcacgc ctttcctcgg
     2641 cctgcgagcg gcgcacgacg cgctgcgctc ggactcgccg ccgctctgcc cggcggcgga
     2701 cagcaggact tactactccc tggacagcca cagcacgcgc gccagcagca gacacagccg
     2761 ggggccgccc acgagggcaa agcaggactc cgggcccctc taaggcctcc cgcctcgccc
     2821 gcctcacgtc tccgaggaga gcggagacca ccgactggag agggaaaaag gagcgaacaa
     2881 agaaataaaa atatttttat tttctataaa aggaaaaaag tataacaaaa tgttttattt
     2941 tcattttagc aaaaaaaatt gtcttataat actagctaac ggcaaagacg tttttatagg
     3001 gaaactattt atatgtaaca tcctgattta cagcttcgga aaaaaaaaag aaacaacaaa
     3061 aaaaaaaaag agagatgggc caattttttt gactctttaa tagaaaccta tattgtggtg
     3121 ccttttgctg tacgctaatc tggggctcct ggagagccgt ctggggtgca gtgtggggat
     3181 gggcgcttat aggatcccaa actggtgggg gtgagaaaag gcaggtaaag aagagactgt
     3241 gaggttctaa tggttctgag ggtaatgaac aatgaggaag aagatgaaga taagacgaaa
     3301 ttttatcttc cccagtccag atctggagtc ctgaacagag agggcaggga tcctagcctt
     3361 cgagctggaa ttgagatggg gttatttcca ggaggagaca caggcctccc gttacagcaa
     3421 ctagaatggg gaaggtcctc cccagccctc acagctgcta agggaaagag gacagagaag
     3481 gctgtctccc caccagcccc cccgcctagg gagggggcag ctctaccagg ggcccaacct
     3541 tcatggctcc tcctcccctg cggcctccag gatgtcctct gtcctctgca gcaccttcgt
     3601 ttacaggtcg tcttttctat tttacgcctg catgtccttc gcatttcaga ttctttagat
     3661 tgaatgcatg gtcacgctgg gacccggaag agccactcca acagtgtatt cgattcccct
     3721 tttagcaata aagtaacacc atatcctcac agcccagctc ccaacccacc tatgactttc
     3781 atcttccagt cctgccctcc ccagccagcc ctcacaactg gatccaatgc taatttgtca
     3841 agaaaaaaaa aaaaaaaaaa agaaaggcag ttgtctaaaa agccaacaaa aatcccgaac
     3901 agaaacaaat gggagccctg acatgtccga gcacctgact gttgacactt gaacattttt
     3961 atattataaa taaaatcaga aataactcct gtttgactgt gtgtacctag ccccaggtga
     4021 ggagggaaga tagaaggagg gcctaggatg aggcatgtgg gtactggaag aaaaattgga
     4081 tagggccaag gtagtccccg agcggaagtg accctctctc cagtccctct ggccccagct
     4141 cccaggacct gctccaagtc ttccttccaa atcatttata aggtgtcccc ctgggtgcta
     4201 aggaacccag ccaagggact gacgcaaatc gttctgcttt aaactcagcc tcagaactct
     4261 agcccagttc ctgccctgca gcgggaagct ggactgaggc aacagttttc tgcccaggtg
     4321 ggtgaagagg aaagggttgt ggggttggca ctggggcagc ggaggcaaag atgacccttg
     4381 gggcttcagg catgtcacag gcagagtctg gacatgtaag acaacataat gggcaccctc
     4441 attgccagaa ggaccagaac agctgctgct cctgagccca caggatattg ctccttccct
     4501 aactgtgtac ccccctcaga gccagggcct gtctaaacat gctgctttga tggtctgatc
     4561 tcaggcatgg aggaggcaga tagagtccag ggtaaagagt ctttcttgtc agctaccaag
     4621 aataccagga acaaatattc tagccagagc ctgaagcctt ctctccagag aggtggggtg
     4681 aatatgtgta cgcttatgca cattcttgaa ggttccagtg tggatctaga cactcacaga
     4741 ggagcgtggc agagaggcag agagcaacga tagggaaatg gggaagcgat tgtgtatatt
     4801 acgcatcgct gtggcggtta cacgaggatg gacccatcaa ttcctgatcg atatctagaa
     4861 gtcttgaagg tagcagtggc agaatcctgt gccttgtaac cgtgaatcac aaagtgggaa
     4921 aaacttgatg aggtgattaa gaaaagttta aacttataaa gtcattatat ttgttatggg
     4981 gtgctgaggg gcacttatta caaaggggaa aaaatgaaag aaaactcgct gggctgaatg
     5041 ttacacagac tgtagatcgt ggcctctcca ggtgacccat tagatctttt ctgctgtctg
     5101 tttgctttcg tagggcagta atccttatgt gggaccccag attaattgct atgacctctt
     5161 ggcgagccca ctgatctcat tatgatcgag gttaatgtcc tcacttaaac tctgtgagga
     5221 ctgcaagttg ttgccttcta ggttttcatc cagaaaccac cagtaggact caaacaaccc
     5281 cagttaacta tgagtgaccc ctcagtgaac tcaccgacct gtacggcccc catttcactc
     5341 cctcatcatc tgccctgggc tctaagataa ccaacccacc aagagtccaa ggccagaact
     5401 taacctcatt tttcattgct ccccttatta catcagccag cattcaatgg acaggtatgg
     5461 ttgggacctg ggaacacgct tgaccagaga gccctcttga ccaccctgac tctcaggttt
     5521 tagccttggg gaggttgagt atgtggcctt tcaggaagca ctgtggtcat tgcaggcgac
     5581 ttcctttcca ccaccctgtc ccctggaaca ctcaggacat tcaggcagct tcctaggtca
     5641 aaattctctt ccccgctccc caagttgttt ctttactttg cattatcact tttagtatct
     5701 tttccccagt ccctctcaga gtcctcggta gcaatggtaa gcacttctcc ccttgtctcc
     5761 ctgataacgg tgagacccat aaacacaggg aattggtctc ttttaccact gtccccagca
     5821 cacagcaacg gtgtatggca catggttgac cctcagtgaa gaggatgaag gctgtttgtc
     5881 aagagttagg caccaggagt tcctgagccc tggagcaaac ctcccgggac cttgtcaggc
     5941 cctggatttg acctgtcctt atgggcttgt taggggtgac agggaagaga agcatgatag
     6001 tctattagaa tgcaggaaaa aaattagaac tttgatttag atttattttc atctcatctt
     6061 ttttaaattt ctatttttgt gtatgtttta taatgtacat aatattttag tacagtagta
     6121 catgtatata atttacaaat aaagaattat acaattaa
//
