LOCUS       NM_031130               2283 bp    mRNA    linear   ROD 28-MAR-2024
DEFINITION  Rattus norvegicus nuclear receptor subfamily 2, group F, member 1
            (Nr2f1), mRNA.
ACCESSION   NM_031130 XM_346611
VERSION     NM_031130.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2283)
  AUTHORS   Chiang,D.Y., Cuthbertson,D.W., Ruiz,F.R., Li,N. and Pereira,F.A.
  TITLE     A coregulatory network of NR2F1 and microRNA-140
  JOURNAL   PLoS One 8 (12), e83358 (2013)
   PUBMED   24349493
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2283)
  AUTHORS   Armentano,M., Chou,S.J., Tomassy,G.S., Leingartner,A., O'Leary,D.D.
            and Studer,M.
  TITLE     COUP-TFI regulates the balance of cortical patterning between
            frontal/motor and sensory areas
  JOURNAL   Nat Neurosci 10 (10), 1277-1286 (2007)
   PUBMED   17828260
REFERENCE   3  (bases 1 to 2283)
  AUTHORS   Tripodi,M., Filosa,A., Armentano,M. and Studer,M.
  TITLE     The COUP-TF nuclear receptors regulate cell migration in the
            mammalian basal forebrain
  JOURNAL   Development 131 (24), 6119-6129 (2004)
   PUBMED   15548577
REFERENCE   4  (bases 1 to 2283)
  AUTHORS   Zhang,Y. and Dufau,M.L.
  TITLE     Nuclear orphan receptors regulate transcription of the gene for the
            human luteinizing hormone receptor
  JOURNAL   J Biol Chem 275 (4), 2763-2770 (2000)
   PUBMED   10644740
REFERENCE   5  (bases 1 to 2283)
  AUTHORS   Yoshikawa,T., Xing,G.Q. and Detera-Wadleigh,S.D.
  TITLE     Detection, simultaneous display and direct sequencing of multiple
            nuclear hormone receptor genes using bilaterally targeted RNA
            fingerprinting
  JOURNAL   Biochim Biophys Acta 1264 (1), 63-71 (1995)
   PUBMED   7578258
REFERENCE   6  (bases 1 to 2283)
  AUTHORS   Connor,H., Nornes,H. and Neuman,T.
  TITLE     Expression screening reveals an orphan receptor chick ovalbumin
            upstream promoter transcription factor I as a regulator of
            neurite/substrate-cell contacts and cell aggregation
  JOURNAL   J Biol Chem 270 (25), 15066-15070 (1995)
   PUBMED   7797489
REFERENCE   7  (bases 1 to 2283)
  AUTHORS   Ben-Shushan,E., Sharir,H., Pikarsky,E. and Bergman,Y.
  TITLE     A dynamic balance between ARP-1/COUP-TFII, EAR-3/COUP-TFI, and
            retinoic acid receptor:retinoid X receptor heterodimers regulates
            Oct-3/4 expression in embryonal carcinoma cells
  JOURNAL   Mol Cell Biol 15 (2), 1034-1048 (1995)
   PUBMED   7823919
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000002.1.
            
            On Nov 25, 2020 this sequence version replaced NM_031130.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26360176.245564.1,
                                           SRR26360176.282276.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN12840111, SAMN12840116
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-722               JAXUCZ010000002.1  9785203-9785924     c
            723-1250            JAXUCZ010000002.1  9782266-9782793     c
            1251-2283           JAXUCZ010000002.1  9776179-9777211     c
FEATURES             Location/Qualifiers
     source          1..2283
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="2"
                     /map="2q11"
     gene            1..2283
                     /gene="Nr2f1"
                     /gene_synonym="COUP-TFI"
                     /note="nuclear receptor subfamily 2, group F, member 1"
                     /db_xref="GeneID:81808"
                     /db_xref="RGD:621682"
     exon            1..722
                     /gene="Nr2f1"
                     /gene_synonym="COUP-TFI"
                     /inference="alignment:Splign:2.1.0"
     CDS             269..1531
                     /gene="Nr2f1"
                     /gene_synonym="COUP-TFI"
                     /codon_start=1
                     /product="COUP transcription factor 1"
                     /protein_id="NP_112392.2"
                     /db_xref="GeneID:81808"
                     /db_xref="RGD:621682"
                     /translation="MAMVVSSWRDPQDDVAGGNPGGPNPAAQAARGGGGGEQQQAGSG
                     APHTPQTPGQPGAPATPGTAGDKGQGPPGSGQSQQHIECVVCGDKSSGKHYGQFTCEG
                     CKSFFKRSVRRNLTYTCRANRNCPIDQHHRNQCQYCRLKKCLKVGMRREAVQRGRMPP
                     TQPNPGQYALTNGDPLNGHCYLSGYISLLLRAEPYPTSRYGSQCMQPNNIMGIENICE
                     LAARLLFSAVEWARNIPFFPDLQITDQVSLLRLTWSELFVLNAAQCSMPLHVAPLLAA
                     AGLHASPMSADRVVAFMDHIRIFQEQVEKLKALHVDSAEYSCLKAIVLFTSDACGLSD
                     AAHIESLQEKSQCALEEYVRSQYPNQPSRFGKLLLRLPSLRTVSSSVIEQLFFVRLVG
                     KTPIETLIRDMLLSGSSFNWPYMSIQCS"
     exon            723..1250
                     /gene="Nr2f1"
                     /gene_synonym="COUP-TFI"
                     /inference="alignment:Splign:2.1.0"
     exon            1251..2283
                     /gene="Nr2f1"
                     /gene_synonym="COUP-TFI"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 acaacaaaac gccagcaggg cgggcgggcg cgcagcagca gcggggcggc cgaggcagta
       61 acggcggcgg cggcggcggc ggcggcggct caggcagagg ccggtgcccg gctcgggctt
      121 ggctccggcg accccggggt gcccggtggg ccccccgccc cctccccctc cccccttccc
      181 cttccccttc ccctcccagc gcgcccgcgc gccccgcggc cctcggcgag cagctcggct
      241 ccccccagcg ctccccgggc ccaaagatat ggcaatggta gttagcagct ggcgagatcc
      301 gcaggacgac gtggccgggg gcaaccccgg cggccccaac cccgcagcgc aggcagcccg
      361 cggcggcggc ggcggcgagc aacagcaggc gggctccggc gcgccgcaca cgccgcagac
      421 cccgggccag cccggagcgc ccgccacccc cggcacggcg ggggacaagg gccagggccc
      481 gccgggttcg ggccagagcc agcagcacat cgagtgcgtg gtgtgcgggg acaagtcgag
      541 cggcaagcac tacggccaat tcacctgcga gggctgcaaa agtttcttca agaggagcgt
      601 ccgcaggaac ttaacttaca catgccgtgc caacaggaac tgtcccatcg accagcacca
      661 ccgcaaccag tgccaatact gccgcctcaa gaagtgcctc aaagtgggca tgaggcggga
      721 agcggttcag cgaggaagaa tgcctccaac ccagcccaat ccaggccagt acgcactcac
      781 aaacggggat cccctcaatg gccactgcta cctgtccggc tacatctccc tgctgctgcg
      841 agcagagccc taccccacgt cgcgttatgg cagccagtgc atgcagccca acaacatcat
      901 gggcatcgag aacatctgcg agttggccgc ccgcctcctc ttcagcgccg tcgagtgggc
      961 ccgcaacatc ccgttcttcc cggatctgca gatcaccgac caggtgtccc tgctacgcct
     1021 cacctggagc gagctgttcg tgctcaacgc ggcccagtgc tccatgcccc tgcacgtggc
     1081 gccgctgctg gcagcagccg gcctacacgc ctcgcccatg tccgcggacc gggtcgtggc
     1141 cttcatggac cacatccgca tctttcagga acaggtggag aagctcaagg cgctgcacgt
     1201 cgactctgcc gagtacagct gcctcaaagc catcgtgctg ttcacgtcag atgcttgtgg
     1261 cctgtcggat gctgcacaca tcgaaagcct gcaggagaaa tcgcagtgtg cactggagga
     1321 atacgtgagg agccagtacc ccaaccagcc cagccgcttt ggcaaactgc tgctgcgatt
     1381 gccctctctt cgcacagtgt cctcttctgt catagagcag ctcttcttcg tccgtttggt
     1441 aggtaaaacc cccatcgaaa ctctcatccg agacatgttg ttgtcaggga gcagtttcaa
     1501 ctggccttac atgtccatcc agtgctccta gaccttgggt gtttcccacc tgcccctgca
     1561 ccccctaact ccctagagac taagcggact caccctgacc aaggactcaa aagcctttgg
     1621 ggatgctggt atgatggcag gccaggcaga ggggaggagg gctgtggaca ggagcggccc
     1681 actctgcagg aatgcaacct gagctgcaaa ccatgagaga aagagactca tttaggatct
     1741 gatctgtaag tacattgaaa tggaaagaaa aagaacctcc tgtctgatga gaaaatggaa
     1801 aaaaaagatt tggaggagag gaccatgaga aatgtaataa aatagaagga ctctgatgga
     1861 ccttccagga tttactgtgg atggatgtgg atatattctg tacagaaaac tacccatatg
     1921 gaagtggact gaatcctatg tagagacaca cactgaacat tgttattcat tttgtaaaat
     1981 actagtcttt attttcattt ttgtaaaatt taaacatcgt atgcgcataa acaaaaatga
     2041 acaagaatta gggggaaata acattttcca aataattata aaatatttgt cctgtgtcta
     2101 tgtatctata tctgttttgt atttttttct ggttccaaac cagatttcct gtgattctat
     2161 actaataatt tttgatataa ccctttgctt cttataatga gtgcgatata tgttgtcgag
     2221 gctgttcttc aagaattaaa attgaagtga aaatttaaac aaaaataaaa gaatttagca
     2281 aaa
//
