LOCUS       NM_031581               1257 bp    mRNA    linear   ROD 03-JUN-2024
DEFINITION  Rattus norvegicus neuropeptide Y receptor Y4 (Npy4r), mRNA.
ACCESSION   NM_031581
VERSION     NM_031581.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1257)
  AUTHORS   Sheng,W., Yu,M., Wang,X., Jin,M., Pang,X., Li,C., Zhang,S., Li,P.,
            Wang,X., Zhang,C., Zhang,Y. and Liu,K.
  TITLE     Localization of neuropeptide receptor NPY4R in rat retina
  JOURNAL   Neuropeptides 93, 102246 (2022)
   PUBMED   35453028
  REMARK    GeneRIF: Localization of neuropeptide receptor NPY4R in rat retina.
REFERENCE   2  (bases 1 to 1257)
  AUTHORS   Yahya,A., Xiao,C., Chance,W.T. and Sheriff,S.
  TITLE     Up-regulation of neuropeptide Y Y4 receptor mRNA expression in the
            brainstem of refed rats following 48 h of food deprivation: effect
            of leptin
  JOURNAL   Peptides 27 (11), 2731-2737 (2006)
   PUBMED   16950545
  REMARK    GeneRIF: results suggest that refeeding stimulates the expression
            of Y4R gene in the brainstem and that leptin may be one of the
            peripheral factors involved in this anorectic signaling mechanism
            [NPY4R]
REFERENCE   3  (bases 1 to 1257)
  AUTHORS   Kanatani,A., Mashiko,S., Murai,N., Sugimoto,N., Ito,J.,
            Fukuroda,T., Fukami,T., Morin,N., MacNeil,D.J., Van der Ploeg,L.H.,
            Saga,Y., Nishimura,S. and Ihara,M.
  TITLE     Role of the Y1 receptor in the regulation of neuropeptide
            Y-mediated feeding: comparison of wild-type, Y1 receptor-deficient,
            and Y5 receptor-deficient mice
  JOURNAL   Endocrinology 141 (3), 1011-1016 (2000)
   PUBMED   10698177
REFERENCE   4  (bases 1 to 1257)
  AUTHORS   Walker,M.W., Smith,K.E., Bard,J., Vaysse,P.J., Gerald,C.,
            Daouti,S., Weinshank,R.L. and Branchek,T.A.
  TITLE     A structure-activity analysis of the cloned rat and human Y4
            receptors for pancreatic polypeptide
  JOURNAL   Peptides 18 (4), 609-612 (1997)
   PUBMED   9210181
REFERENCE   5  (bases 1 to 1257)
  AUTHORS   Lundell,I., Statnick,M.A., Johnson,D., Schober,D.A., Starback,P.,
            Gehlert,D.R. and Larhammar,D.
  TITLE     The cloned rat pancreatic polypeptide receptor exhibits profound
            differences to the orthologous receptor
  JOURNAL   Proc Natl Acad Sci U S A 93 (10), 5111-5115 (1996)
   PUBMED   8643536
REFERENCE   6  (bases 1 to 1257)
  AUTHORS   Yan,H., Yang,J., Marasco,J., Yamaguchi,K., Brenner,S., Collins,F.
            and Karbon,W.
  TITLE     Cloning and functional expression of cDNAs encoding human and rat
            pancreatic polypeptide receptors
  JOURNAL   Proc Natl Acad Sci U S A 93 (10), 4661-4665 (1996)
   PUBMED   8643460
REFERENCE   7  (bases 1 to 1257)
  AUTHORS   Gregor,P., Millham,M.L., Feng,Y., DeCarr,L.B., McCaleb,M.L. and
            Cornfield,L.J.
  TITLE     Cloning and characterization of a novel receptor to pancreatic
            polypeptide, a member of the neuropeptide Y receptor family
  JOURNAL   FEBS Lett 381 (1-2), 58-62 (1996)
   PUBMED   8641440
REFERENCE   8  (bases 1 to 1257)
  AUTHORS   Lundell,I., Blomqvist,A.G., Berglund,M.M., Schober,D.A.,
            Johnson,D., Statnick,M.A., Gadski,R.A., Gehlert,D.R. and
            Larhammar,D.
  TITLE     Cloning of a human receptor of the NPY receptor family with high
            affinity for pancreatic polypeptide and peptide YY
  JOURNAL   J Biol Chem 270 (49), 29123-29128 (1995)
   PUBMED   7493937
REFERENCE   9  (bases 1 to 1257)
  AUTHORS   Bard,J.A., Walker,M.W., Branchek,T.A. and Weinshank,R.L.
  TITLE     Cloning and functional expression of a human Y4 subtype receptor
            for pancreatic polypeptide, neuropeptide Y, and peptide YY
  JOURNAL   J Biol Chem 270 (45), 26762-26765 (1995)
   PUBMED   7592911
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from U42388.1.
            
            On Aug 30, 2012 this sequence version replaced NM_031581.1.
            
            ##Evidence-Data-START##
            Transcript is intronless :: U42388.1 [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1257              U42388.1           3-1259
FEATURES             Location/Qualifiers
     source          1..1257
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="16"
                     /map="16p15"
     gene            1..1257
                     /gene="Npy4r"
                     /gene_synonym="Ppyr1"
                     /note="neuropeptide Y receptor Y4"
                     /db_xref="GeneID:29471"
                     /db_xref="RGD:61864"
     exon            1..1257
                     /gene="Npy4r"
                     /gene_synonym="Ppyr1"
                     /inference="alignment:Splign:2.1.0"
     CDS             62..1189
                     /gene="Npy4r"
                     /gene_synonym="Ppyr1"
                     /note="PP1; NPY4-R; pancreatic polypeptide receptor 1"
                     /codon_start=1
                     /product="neuropeptide Y receptor type 4"
                     /protein_id="NP_113769.1"
                     /db_xref="GeneID:29471"
                     /db_xref="RGD:61864"
                     /translation="MNTSHLMASLSPAFLQGKNGTNSLDSLYNLSDGCQDSADLLAFI
                     ITTYSVETVLGVLGNLCLIFVTTRQKEKSNVTNLLIANLAFSDFLMCLICQPLTVTYT
                     IMDYWIFGEVLCKMLTFIQCMSVTVSILSLVLVALERHQLIINPTGWKPSISQAYLGI
                     VVIWFISCFLSLPFLANSILNDLFHYNHSKVVEFLEDKVVCFVSWSSDHHRLIYTTFL
                     LLFQYCVPLAFILVCYMRIYQRLQRQRRAFHTHTCSSRVGQMKRINGMLMAMVTAFAV
                     LWLPLHVFNTLEDWYQEAIPACHGNLIFLMCHLFAMASTCVNPFIYGFLNINFKKDIK
                     ALVLTCRCRPPQGEPEPLPLSTVHTDLSKGSMRMGSKSNVM"
ORIGIN      
        1 gcaggctaca ctcagaagtg ggccctttag tcttgaagtt cctggtcttc tcacacccac
       61 catgaatacc tctcatctca tggcctccct ttctccggca ttcctacaag gtaagaatgg
      121 gaccaactca ctggattccc tctataatct ctctgacggc tgccaggatt cggcagatct
      181 gttggccttc atcatcacca cctacagcgt tgagaccgtc ttgggggtcc taggaaacct
      241 ctgcttgata tttgtgacca caaggcaaaa ggaaaagtcc aatgtgacca acctactcat
      301 tgccaacctg gccttctctg acttcctcat gtgtctcatc tgccagccgc tcacggtcac
      361 ctacaccatc atggactact ggatcttcgg cgaagtcctt tgcaagatgt taacgttcat
      421 ccagtgtatg tcggtgacag tctccatcct ctcactggtc cttgtggccc tggagaggca
      481 ccagctcatt atcaacccga ctggctggaa acccagcatt tcccaggcct acctggggat
      541 tgtggtcatc tggttcattt cttgtttcct ctccttgccc ttcctggcca atagcatcct
      601 gaacgacctc ttccactaca accactctaa ggttgtggag tttctggaag acaaggttgt
      661 ctgctttgtg tcctggtcct cggatcacca ccgcctcatc tacaccacct ttctgctgct
      721 cttccaatac tgcgtccctc tggccttcat cctggtctgc tacatgcgta tctaccagcg
      781 cctgcagagg cagaggcgtg cgttccacac gcacacttgc agctcacgag tggggcagat
      841 gaagcggatc aatggcatgc tcatggcaat ggtgactgcc tttgcagttc tctggctgcc
      901 cctgcatgtg ttcaacactc tggaggactg gtaccaggaa gccatccctg cttgccatgg
      961 caacctcatc ttcttgatgt gccacctgtt tgccatggct tccacctgtg tcaacccttt
     1021 catctatggc tttctcaaca tcaacttcaa gaaggacatc aaggctctgg ttctgacctg
     1081 ccgttgcagg ccacctcaag gggagcctga gcctctgccc ctgtccactg tgcacacgga
     1141 cctctccaag ggatctatga ggatgggtag caagtctaac gtcatgtagt catgtctagg
     1201 ctcttccgcc attttctttc gacacaccct ttcactgagc taagtagaca caatgca
//
