LOCUS       NM_001401107             945 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus nucleophosmin/nucleoplasmin, 3 (Npm3), mRNA.
ACCESSION   NM_001401107 XM_577868
VERSION     NM_001401107.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 945)
  AUTHORS   Baltz,A.G., Munschauer,M., Schwanhausser,B., Vasile,A.,
            Murakawa,Y., Schueler,M., Youngs,N., Penfold-Brown,D., Drew,K.,
            Milek,M., Wyler,E., Bonneau,R., Selbach,M., Dieterich,C. and
            Landthaler,M.
  TITLE     The mRNA-bound proteome and its global occupancy profile on
            protein-coding transcripts
  JOURNAL   Mol Cell 46 (5), 674-690 (2012)
   PUBMED   22681889
REFERENCE   2  (bases 1 to 945)
  AUTHORS   Castello,A., Fischer,B., Eichelbaum,K., Horos,R., Beckmann,B.M.,
            Strein,C., Davey,N.E., Humphreys,D.T., Preiss,T., Steinmetz,L.M.,
            Krijgsveld,J. and Hentze,M.W.
  TITLE     Insights into RNA biology from an atlas of mammalian mRNA-binding
            proteins
  JOURNAL   Cell 149 (6), 1393-1406 (2012)
   PUBMED   22658674
REFERENCE   3  (bases 1 to 945)
  AUTHORS   Pradeepa,M.M., Nikhil,G., Hari Kishore,A., Bharath,G.N., Kundu,T.K.
            and Rao,M.R.
  TITLE     Acetylation of transition protein 2 (TP2) by KAT3B (p300) alters
            its DNA condensation property and interaction with putative histone
            chaperone NPM3
  JOURNAL   J Biol Chem 284 (43), 29956-29967 (2009)
   PUBMED   19710011
  REMARK    GeneRIF: Acetylation of transition protein 2 (TP2) by KAT3B (p300)
            alters its DNA condensation property and interaction with putative
            histone chaperone NPM3.
REFERENCE   4  (bases 1 to 945)
  AUTHORS   Huang,N., Negi,S., Szebeni,A. and Olson,M.O.
  TITLE     Protein NPM3 interacts with the multifunctional nucleolar protein
            B23/nucleophosmin and inhibits ribosome biogenesis
  JOURNAL   J Biol Chem 280 (7), 5496-5502 (2005)
   PUBMED   15596447
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000001.1.
            
            On Feb 2, 2022 this sequence version replaced XM_577868.8.
            
            ##Evidence-Data-START##
            Transcript exon combination :: FM029626.1, SRR26360181.1121969.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760386 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-162               JAXUCZ010000001.1  254546488-254546649 c
            163-248             JAXUCZ010000001.1  254546117-254546202 c
            249-368             JAXUCZ010000001.1  254545772-254545891 c
            369-462             JAXUCZ010000001.1  254545566-254545659 c
            463-573             JAXUCZ010000001.1  254545127-254545237 c
            574-945             JAXUCZ010000001.1  254544664-254545035 c
FEATURES             Location/Qualifiers
     source          1..945
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q54"
     gene            1..945
                     /gene="Npm3"
                     /gene_synonym="RGD1565542"
                     /note="nucleophosmin/nucleoplasmin, 3"
                     /db_xref="GeneID:502389"
                     /db_xref="RGD:1565542"
     exon            1..162
                     /gene="Npm3"
                     /gene_synonym="RGD1565542"
                     /inference="alignment:Splign:2.1.0"
     CDS             45..566
                     /gene="Npm3"
                     /gene_synonym="RGD1565542"
                     /note="nucleoplasmin 3"
                     /codon_start=1
                     /product="nucleoplasmin-3"
                     /protein_id="NP_001388036.1"
                     /db_xref="GeneID:502389"
                     /db_xref="RGD:1565542"
                     /translation="MAAGAAAALAFLNQESRARARGLGGLRVPAPVTMDSFFFGCELS
                     SHTRSFTFKVEEEDDTEHVLALNMLCLTEGAKDECNVVEVVARDHDNQEIAVPVANLR
                     LSCQPMLSVDDFQLQPPVTFRLKSGSGPVRITGRHQIVCINNDLSEESPDESEDEIKL
                     CGILPAKKHRGRP"
     exon            163..248
                     /gene="Npm3"
                     /gene_synonym="RGD1565542"
                     /inference="alignment:Splign:2.1.0"
     exon            249..368
                     /gene="Npm3"
                     /gene_synonym="RGD1565542"
                     /inference="alignment:Splign:2.1.0"
     exon            369..462
                     /gene="Npm3"
                     /gene_synonym="RGD1565542"
                     /inference="alignment:Splign:2.1.0"
     exon            463..573
                     /gene="Npm3"
                     /gene_synonym="RGD1565542"
                     /inference="alignment:Splign:2.1.0"
     exon            574..945
                     /gene="Npm3"
                     /gene_synonym="RGD1565542"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggcgttcggt gcgtgggggg cggggctctc acggccgttt cagcatggcc gccggcgccg
       61 cggctgcttt ggcgttcttg aaccaagaga gccgagccag ggctcggggc ctcgggggcc
      121 tgagggttcc ggctccggtc acaatggata gtttcttctt cggttgtgag ctctccagcc
      181 acacccgctc ctttactttc aaggttgagg aagaggatga tacagaacat gtgctggctt
      241 tgaacatgct gtgccttacc gagggtgcca aggacgagtg taatgtggtg gaagttgtgg
      301 cccgcgatca cgacaatcag gagattgcag ttcctgtggc caacctcagg ttgtcttgcc
      361 agcccatgct cagtgtagat gacttccagc tccaaccacc tgtaacgttc cgcctcaagt
      421 ccggttctgg ccctgtgcgg atcactggtc ggcatcagat cgtttgtata aacaacgatc
      481 tttctgaaga aagtccggat gagagtgaag atgaaattaa gctgtgtgga atccttcctg
      541 ccaaaaagca taggggcagg ccttagccct ctggtcaggg agctgcttgc tacaggtgcc
      601 atgttccatg tgtccctgga caagttcaag gatggttttc tcgctgaaga ggatggttta
      661 ggaagggggt gggtgggagg gacttaggct ggtctgagag accagtcatt ctccttaggg
      721 tcctgtggtt cctgaagttt cccttttctt ctggaatggg gatgaccttt gaacacctct
      781 tataacccac ctacccagac taaaagtttt gtaaagcccc aggttcaatc cccagcacta
      841 caaaacaaaa caaaaaaaaa ccaccatgaa gttcagagca catttttaac actttttaca
      901 tttttagata aatatctaaa taaagtggtg tatggttttt tgcaa
//
