LOCUS       NM_203340                926 bp    mRNA    linear   ROD 09-APR-2024
DEFINITION  Rattus norvegicus nucleophosmin/nucleoplasmin 2 (Npm2), mRNA.
ACCESSION   NM_203340 XM_224343
VERSION     NM_203340.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 926)
  AUTHORS   Wajapeyee,N., Malonia,S.K., Palakurthy,R.K. and Green,M.R.
  TITLE     Oncogenic RAS directs silencing of tumor suppressor genes through
            ordered recruitment of transcriptional repressors
  JOURNAL   Genes Dev 27 (20), 2221-2226 (2013)
   PUBMED   24105743
REFERENCE   2  (bases 1 to 926)
  AUTHORS   Burns,K.H., Viveiros,M.M., Ren,Y., Wang,P., DeMayo,F.J.,
            Frail,D.E., Eppig,J.J. and Matzuk,M.M.
  TITLE     Roles of NPM2 in chromatin and nucleolar organization in oocytes
            and embryos
  JOURNAL   Science 300 (5619), 633-636 (2003)
   PUBMED   12714744
REFERENCE   3  (bases 1 to 926)
  AUTHORS   Umekawa,H., Sato,K., Takemura,M., Watanabe,Y., Usui,S.,
            Takahashi,T., Yoshida,S., Olson,M.O. and Furuichi,Y.
  TITLE     The carboxyl terminal sequence of nucleolar protein B23.1 is
            important in its DNA polymerase alpha-stimulatory activity
  JOURNAL   J Biochem 130 (2), 199-205 (2001)
   PUBMED   11481036
REFERENCE   4  (bases 1 to 926)
  AUTHORS   Herrera,J.E., Correia,J.J., Jones,A.E. and Olson,M.O.
  TITLE     Sedimentation analyses of the salt- and divalent metal ion-induced
            oligomerization of nucleolar protein B23
  JOURNAL   Biochemistry 35 (8), 2668-2673 (1996)
   PUBMED   8611572
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000015.1.
            
            On Sep 13, 2022 this sequence version replaced NM_203340.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BK001252.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760389, SAMN17050755
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-148               JAXUCZ010000015.1  52138880-52139027   c
            149-234             JAXUCZ010000015.1  52138684-52138769   c
            235-348             JAXUCZ010000015.1  52138479-52138592   c
            349-442             JAXUCZ010000015.1  52136252-52136345   c
            443-597             JAXUCZ010000015.1  52134905-52135059   c
            598-635             JAXUCZ010000015.1  52134691-52134728   c
            636-669             JAXUCZ010000015.1  52132311-52132344   c
            670-926             JAXUCZ010000015.1  52131973-52132229   c
FEATURES             Location/Qualifiers
     source          1..926
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="15"
                     /map="15p11"
     gene            1..926
                     /gene="Npm2"
                     /note="nucleophosmin/nucleoplasmin 2"
                     /db_xref="GeneID:290359"
                     /db_xref="RGD:727816"
     exon            1..148
                     /gene="Npm2"
                     /inference="alignment:Splign:2.1.0"
     CDS             91..714
                     /gene="Npm2"
                     /codon_start=1
                     /product="nucleoplasmin-2"
                     /protein_id="NP_976085.1"
                     /db_xref="GeneID:290359"
                     /db_xref="RGD:727816"
                     /translation="MSRHSTSSMTETTAKNMLWGSELTQEKQTCTFRAQGERKDSCKL
                     LLSTICLGEKAKEEVNRVEILPQEDRKSPITVATLKASVLPMVTVTGIELSPPVTFRL
                     RAGSGPVFLSGQECYETSDMAWEDDEEEEEEEEEDEDEDEDADLSLEEIPIKQVKRAA
                     PQRPTSIAKRKKVDKEEEAAVRPSPQDKSPWKKGKSTPKPKRSTSKK"
     exon            149..234
                     /gene="Npm2"
                     /inference="alignment:Splign:2.1.0"
     exon            235..348
                     /gene="Npm2"
                     /inference="alignment:Splign:2.1.0"
     exon            349..442
                     /gene="Npm2"
                     /inference="alignment:Splign:2.1.0"
     exon            443..597
                     /gene="Npm2"
                     /inference="alignment:Splign:2.1.0"
     exon            598..635
                     /gene="Npm2"
                     /inference="alignment:Splign:2.1.0"
     exon            636..669
                     /gene="Npm2"
                     /inference="alignment:Splign:2.1.0"
     exon            670..926
                     /gene="Npm2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 aaaacagtga taacagctga actccaagca gggacccagg accttacctc atcacagaca
       61 taattcttcc cccccaccca gtaaatcgac atgagtcgcc acagcaccag cagcatgact
      121 gaaaccacgg caaagaacat gctctggggc agtgagctca ctcaggaaaa acagacttgc
      181 acctttagag cccaaggcga gaggaaggac agctgtaagc ttttgctcag cacgatttgc
      241 ctgggggaga aggccaaaga ggaggtgaat cgtgtggaaa tccttcccca ggaagacagg
      301 aaatcaccaa tcactgtcgc cacgctgaag gcctctgtcc tgcctatggt cacagtgaca
      361 ggtatagagc tttctcctcc agtaactttt cgtctcaggg ctggctcagg acctgtgttc
      421 ctcagtggcc aggaatgtta tgagacttca gacatggcct gggaagatga tgaggaagag
      481 gaagaggaag aggaagagga tgaagatgag gatgaagatg cagatctatc gctagaagag
      541 atccctatca aacaagtcaa aagggcagct ccccagaggc cgacgagcat agctaagaga
      601 aaaaaggtgg acaaagagga ggaggcggca gtgaggccca gccctcagga caagagcccc
      661 tggaagaagg gaaaatctac acccaaacct aagaggtcga cgtccaagaa atgagctcat
      721 cttagcagct tctgtgtcca aggcgggatg tctaccagct gtgctctggt gcaggtgtcc
      781 ggccccagca ccttagtcta aatgtaatag ggtattgtgg gagctataca ggagccctgc
      841 aacccagccc tccagtttcc ggagacttcg gagaacctcc agcaagcacg cacgggccac
      901 aataaaattt gcatgatcag aacctc
//
