LOCUS       NM_001107479            1965 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus neuronal PAS domain protein 1 (Npas1), mRNA.
ACCESSION   NM_001107479 XM_001074492 XM_238770
VERSION     NM_001107479.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1965)
  AUTHORS   Wu,D., Su,X., Potluri,N., Kim,Y. and Rastinejad,F.
  TITLE     NPAS1-ARNT and NPAS3-ARNT crystal structures implicate the bHLH-PAS
            family as multi-ligand binding transcription factors
  JOURNAL   Elife 5, e18790 (2016)
   PUBMED   27782878
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1965)
  AUTHORS   Flandin,P., Kimura,S. and Rubenstein,J.L.
  TITLE     The progenitor zone of the ventral medial ganglionic eminence
            requires Nkx2-1 to generate most of the globus pallidus but few
            neocortical interneurons
  JOURNAL   J Neurosci 30 (8), 2812-2823 (2010)
   PUBMED   20181579
REFERENCE   3  (bases 1 to 1965)
  AUTHORS   Ohsawa,S., Hamada,S., Kakinuma,Y., Yagi,T. and Miura,M.
  TITLE     Novel function of neuronal PAS domain protein 1 in erythropoietin
            expression in neuronal cells
  JOURNAL   J Neurosci Res 79 (4), 451-458 (2005)
   PUBMED   15635607
REFERENCE   4  (bases 1 to 1965)
  AUTHORS   Erbel-Sieler,C., Dudley,C., Zhou,Y., Wu,X., Estill,S.J., Han,T.,
            Diaz-Arrastia,R., Brunskill,E.W., Potter,S.S. and McKnight,S.L.
  TITLE     Behavioral and regulatory abnormalities in mice deficient in the
            NPAS1 and NPAS3 transcription factors
  JOURNAL   Proc Natl Acad Sci U S A 101 (37), 13648-13653 (2004)
   PUBMED   15347806
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473979.2.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_001074492.1, XM_238770.4.
            
            ##Evidence-Data-START##
            RNAseq introns :: mixed sample support SAMD00132263, SAMD00132266
                              [ECO:0006172]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..1965
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q21"
     gene            1..1965
                     /gene="Npas1"
                     /note="neuronal PAS domain protein 1"
                     /db_xref="GeneID:308387"
                     /db_xref="RGD:1310040"
     exon            1..182
                     /gene="Npas1"
                     /inference="alignment:Splign:2.1.0"
     CDS             61..1848
                     /gene="Npas1"
                     /codon_start=1
                     /product="neuronal PAS domain-containing protein 1"
                     /protein_id="NP_001100949.1"
                     /db_xref="GeneID:308387"
                     /db_xref="RGD:1310040"
                     /translation="MATPYPRSGGRGEVKCGGGRGAGVPWDFLPGLMVKAPPGPCLQA
                     QRKEKSRNAARWRRGKENLEFFELAKLLPLPGAISSQLDKASIVRLSVTYLRLRRFAA
                     LGAPPWGLRAVGPPAGLAPGRRGAVALVSEVFEQHLGGHILQSLDGFVFALNQEGKFL
                     YISETVSIYLGLSQVELTGSSVFDYIHPGDHSEVLEQLGLRAATTGPPTPPSVSSTSS
                     SSSSSSLVDTPEIEASPTEASPAFRVQERSFFVRMKSTLTKRGLNVKASGYKVIHVTG
                     RLRARALGLVALGHTLPPAPLAELPLHGHMIVFRLSLGLTILACESRVSDHMDMGPSE
                     LVGRSCYQFVHGQDVTRIRQSHLDLLDKGQVVTGYYRWLQRAGGFVWLQSVATVAGNG
                     KSAGEHHVLWVSHVLSHAEGGQTPLDAFQLPAIVSQEESSSPGPEPTKEEPPVERKQT
                     VPVEQDKDKDPQARGKRIKVEASPKEVRGSEDSGEEEVSDPPAPPRPEFTSVIRAGAL
                     KHDPVLPWGLTTPGDPSPALLHAGFLPPVVRGLCTPGTIRYGPAELSLMYPHLHRLGP
                     GPSLPEAFYPTLGLPYPGPTGTRVQRKGD"
     exon            183..418
                     /gene="Npas1"
                     /inference="alignment:Splign:2.1.0"
     exon            419..492
                     /gene="Npas1"
                     /inference="alignment:Splign:2.1.0"
     exon            493..582
                     /gene="Npas1"
                     /inference="alignment:Splign:2.1.0"
     exon            583..754
                     /gene="Npas1"
                     /inference="alignment:Splign:2.1.0"
     exon            755..870
                     /gene="Npas1"
                     /inference="alignment:Splign:2.1.0"
     exon            871..1028
                     /gene="Npas1"
                     /inference="alignment:Splign:2.1.0"
     exon            1029..1135
                     /gene="Npas1"
                     /inference="alignment:Splign:2.1.0"
     exon            1136..1283
                     /gene="Npas1"
                     /inference="alignment:Splign:2.1.0"
     exon            1284..1378
                     /gene="Npas1"
                     /inference="alignment:Splign:2.1.0"
     exon            1379..1965
                     /gene="Npas1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ccagggaact gagccccacc tgcgactcct tcgcgcctga attctcgagt cccggtcgag
       61 atggcgaccc cctatcccag aagcggtggc cgaggtgaag ttaagtgcgg gggaggccgt
      121 ggagccggcg tcccctggga tttcctgccc gggctgatgg tcaaggcccc tcccggaccc
      181 tgcctgcagg cgcagcgcaa agagaagtcc cgcaacgcgg cgcgctggcg gcgcggaaag
      241 gaaaatctcg agttcttcga gctggccaag ttgctccctc tgcccggtgc catctccagt
      301 cagctggaca aggcgtccat agtgcgtctt agcgtcacat acctccgcct gcgtcggttt
      361 gcggctctgg gagcgcctcc ctgggggttg cgggccgtcg ggcctcccgc tggcctcgcc
      421 ccaggtcgcc gaggcgctgt ggctctggtg tctgaagtct tcgagcaaca cctaggtgga
      481 cacatcctac agtccttgga tggcttcgtg ttcgccttga accaggaagg gaaattcctc
      541 tacatctcag agacagtgtc catctacttg ggtctctcac aggtggagct gacgggcagc
      601 agcgtcttcg actacatcca tcctggggac cactcggagg tcctagagca acttggactg
      661 agggccgcaa ccactggccc ccctacgccg ccttctgtgt cctccacttc ctcctcgtcg
      721 tcttcctcct cgctggtgga cacccccgag attgaagcca gccccacgga ggcatcccct
      781 gccttccggg tccaggagcg gtccttcttt gtccgaatga agtctaccct caccaagagg
      841 ggtctgaatg tcaaagcctc ggggtacaag gtcattcatg tgacaggacg cctgagggcc
      901 cgagcgctgg gtcttgtagc ccttggacac acgctgcccc cagccccgct ggctgagctg
      961 cctctgcatg gacacatgat tgtgtttcgc ctcagcctgg gcctcaccat ccttgcttgt
     1021 gagagcagag tgagcgacca tatggacatg gggccctcag aactggtggg acgcagctgc
     1081 tatcagtttg tccacggaca ggatgtgacc aggatccgcc aaagccatct ggacctgctg
     1141 gacaaagggc aggtggtgac tggttactac cgttggctgc agcgtgcggg gggcttcgtg
     1201 tggctgcagt ctgtagccac tgtggccggg aacgggaaga gtgctgggga gcatcacgtg
     1261 ctgtgggtca gtcacgtgct cagccatgct gaaggtggtc aaacacccct ggatgccttc
     1321 cagcttccag ccattgtgtc tcaggaggag tcatccagcc caggcccaga gcccacaaag
     1381 gaagagcctc cagttgagcg gaaacagact gtgcctgtgg aacaggacaa ggacaaggac
     1441 cctcaggccc gaggcaaacg catcaaagtg gaggccagcc cgaaggaagt tagaggctca
     1501 gaagacagtg gagaggaaga ggtctcggat ccaccggctc cgcctcggcc ggaattcact
     1561 tctgtcatta gagcaggggc cctgaagcat gatccagtac tgccgtgggg tttgacaact
     1621 cctggagacc cctcgcctgc cctccttcat gcaggcttcc tgccacccgt tgtgcgaggc
     1681 ctgtgtaccc caggcaccat ccgttatggc cctgcagagt taagcctgat gtatccacat
     1741 ctgcacaggc tgggtccagg cccctcgctt ccagaggcct tttaccctac gctgggcctg
     1801 ccctatccgg ggcccacagg tactagggtg cagcgaaagg gagactgaaa acagtgtaac
     1861 accggagggc caaacctgag gcatagatca agtgctggag tcattcttga gaattaaaca
     1921 ccacttcctg aggggctcca tcctcaggga ttcggcctct cgtga
//
