LOCUS       NM_001100171            1378 bp    mRNA    linear   ROD 02-JUN-2024
DEFINITION  Rattus norvegicus NADPH oxidase activator 1 (Noxa1), mRNA.
ACCESSION   NM_001100171 XM_001077267 XM_231042
VERSION     NM_001100171.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1378)
  AUTHORS   Streeter,J., Schickling,B.M., Jiang,S., Stanic,B., Thiel,W.H.,
            Gakhar,L., Houtman,J.C. and Miller,F.J. Jr.
  TITLE     Phosphorylation of Nox1 regulates association with NoxA1 activation
            domain
  JOURNAL   Circ Res 115 (11), 911-918 (2014)
   PUBMED   25228390
REFERENCE   2  (bases 1 to 1378)
  AUTHORS   Gianni,D., DerMardirossian,C. and Bokoch,G.M.
  TITLE     Direct interaction between Tks proteins and the N-terminal
            proline-rich region (PRR) of NoxA1 mediates Nox1-dependent ROS
            generation
  JOURNAL   Eur J Cell Biol 90 (2-3), 164-171 (2011)
   PUBMED   20609497
REFERENCE   3  (bases 1 to 1378)
  AUTHORS   Gianni,D., Diaz,B., Taulet,N., Fowler,B., Courtneidge,S.A. and
            Bokoch,G.M.
  TITLE     Novel p47(phox)-related organizers regulate localized NADPH oxidase
            1 (Nox1) activity
  JOURNAL   Sci Signal 2 (88), ra54 (2009)
   PUBMED   19755710
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 1378)
  AUTHORS   Kawahara,T., Quinn,M.T. and Lambeth,J.D.
  TITLE     Molecular evolution of the reactive oxygen-generating NADPH oxidase
            (Nox/Duox) family of enzymes
  JOURNAL   BMC Evol Biol 7, 109 (2007)
   PUBMED   17612411
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 1378)
  AUTHORS   Cheng,G., Diebold,B.A., Hughes,Y. and Lambeth,J.D.
  TITLE     Nox1-dependent reactive oxygen generation is regulated by Rac1
  JOURNAL   J Biol Chem 281 (26), 17718-17726 (2006)
   PUBMED   16636067
REFERENCE   6  (bases 1 to 1378)
  AUTHORS   Birney,E., Andrews,D., Caccamo,M., Chen,Y., Clarke,L., Coates,G.,
            Cox,T., Cunningham,F., Curwen,V., Cutts,T., Down,T., Durbin,R.,
            Fernandez-Suarez,X.M., Flicek,P., Graf,S., Hammond,M., Herrero,J.,
            Howe,K., Iyer,V., Jekosch,K., Kahari,A., Kasprzyk,A., Keefe,D.,
            Kokocinski,F., Kulesha,E., London,D., Longden,I., Melsopp,C.,
            Meidl,P., Overduin,B., Parker,A., Proctor,G., Prlic,A., Rae,M.,
            Rios,D., Redmond,S., Schuster,M., Sealy,I., Searle,S., Severin,J.,
            Slater,G., Smedley,D., Smith,J., Stabenau,A., Stalker,J.,
            Trevanion,S., Ureta-Vidal,A., Vogel,J., White,S., Woodwark,C. and
            Hubbard,T.J.
  TITLE     Ensembl 2006
  JOURNAL   Nucleic Acids Res 34 (Database issue), D556-D561 (2006)
   PUBMED   16381931
REFERENCE   7  (bases 1 to 1378)
  AUTHORS   Banfi,B., Clark,R.A., Steger,K. and Krause,K.H.
  TITLE     Two novel proteins activate superoxide generation by the NADPH
            oxidase NOX1
  JOURNAL   J Biol Chem 278 (6), 3510-3513 (2003)
   PUBMED   12473664
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BR000299.1.
            
            On or before Jul 29, 2007 this sequence version replaced
            XM_231042.4, XM_001077267.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BR000299.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5756307 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1378
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="3"
                     /map="3p13"
     gene            1..1378
                     /gene="Noxa1"
                     /note="NADPH oxidase activator 1"
                     /db_xref="GeneID:311793"
                     /db_xref="RGD:1306687"
     CDS             1..1341
                     /gene="Noxa1"
                     /note="predicted NADPH oxidase activator 1"
                     /codon_start=1
                     /product="NADPH oxidase activator 1"
                     /protein_id="NP_001093641.1"
                     /db_xref="GeneID:311793"
                     /db_xref="RGD:1306687"
                     /translation="MSSLGDQIRDWHRGVLAVAREDWDSALCFFSDVREPLAKMYFNM
                     GCVHLMAGDPEAALRAFDQAVTKDTCMAVGFLQRGVANFQLQRLQEAVSDFQLALAQL
                     RGNAAIDYTQLGLDFKLQAWEVLYNMASVQCQAGLWTKAANTLVEAISKRPEGAQDTL
                     EAAMDKVQKQVPLQLRQVPKGEVFQPPRRYLKHLEPMDFLGKAKVVASVIPDDHNSDI
                     QPQQSSQVEQAGLQSSSPVCKRVLSTRGGHMSPGLWDSLLATGGPVPGPSEDSSSAEG
                     TATKDPESLVTVTVQCHFTVPLKVPRGTDLSSFRTLLSQALLQQTQKGQFSYKARGED
                     RAWVPISTEDSLQSVWRNVPVSPRGLQLQCRGAWGRPVLYQVVAQYDYRAQRPEDLDF
                     RQGDTVDVLCEVDEAWLEGHRDGRVGIFPKCFVVPAATCVEALPVPEPQPGEQH"
     exon            1..177
                     /gene="Noxa1"
                     /inference="alignment:Splign:2.1.0"
     exon            178..260
                     /gene="Noxa1"
                     /inference="alignment:Splign:2.1.0"
     exon            261..369
                     /gene="Noxa1"
                     /inference="alignment:Splign:2.1.0"
     exon            370..504
                     /gene="Noxa1"
                     /inference="alignment:Splign:2.1.0"
     exon            505..612
                     /gene="Noxa1"
                     /inference="alignment:Splign:2.1.0"
     exon            613..666
                     /gene="Noxa1"
                     /inference="alignment:Splign:2.1.0"
     exon            667..736
                     /gene="Noxa1"
                     /inference="alignment:Splign:2.1.0"
     exon            737..825
                     /gene="Noxa1"
                     /inference="alignment:Splign:2.1.0"
     exon            826..980
                     /gene="Noxa1"
                     /inference="alignment:Splign:2.1.0"
     exon            981..1095
                     /gene="Noxa1"
                     /inference="alignment:Splign:2.1.0"
     exon            1096..1210
                     /gene="Noxa1"
                     /inference="alignment:Splign:2.1.0"
     exon            1211..1378
                     /gene="Noxa1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atgagctctc taggggatca gatacgggac tggcaccggg gcgtactggc cgtagcacgc
       61 gaagactggg actctgcact gtgcttcttt tcagatgtcc gggagccgct ggctaagatg
      121 tacttcaaca tgggctgcgt gcacctgatg gcaggggatc ccgaggctgc gctgagggca
      181 tttgaccaag cagtgaccaa ggacacctgc atggctgttg gcttcctcca gcggggagtg
      241 gccaatttcc agctgcagag gctccaggag gctgtgtccg acttccagtt ggccctggca
      301 cagctgaggg gcaatgctgc cattgactac acacaactgg gtctggactt caaactgcaa
      361 gcctgggagg tcctatataa catggcatca gtgcagtgcc aggcagggct ctggaccaag
      421 gctgccaata ctctagtaga agcaatctcc aaacggccag agggggccca agacaccctg
      481 gaggctgcca tggacaaagt gcagaaacag gtaccactgc agctgcggca agtgcccaag
      541 ggggaggtct tccagcctcc tcggcgatac ctgaaacatc tggagcccat ggatttcctc
      601 ggcaaggcta aggtggtggc ttctgtcatc cctgatgacc acaactcgga catccagcct
      661 cagcagagct cccaggtgga gcaagccggc ctccagtcgt cctcacccgt gtgtaagagg
      721 gtcctgagca caaggggtgg tcacatgagc cctggcctat gggacagttt gctggcaact
      781 ggagggcctg tcccgggccc ctctgaagat tcctctagtg ctgagggaac agctacaaag
      841 gaccctgaat ccttggtgac tgtcactgtg cagtgccact ttactgtgcc cctgaaggtc
      901 cccagaggaa ctgacctgtc cagttttcgg acactactgt ctcaagctct ccttcagcag
      961 acccagaagg ggcagttcag ctacaaagcc cgaggagagg acagagcctg ggtccccatc
     1021 tccacggagg actcactgca gagtgtatgg aggaatgtgc cagtgagccc aagaggcttg
     1081 cagctccagt gccggggggc ctggggccgg ccagtcctct accaagtggt agctcagtac
     1141 gactatcgtg cccaaaggcc ggaggacttg gacttccgcc aaggggacac agtggatgtt
     1201 ctgtgtgaag tggacgaagc atggctggag ggacaccgag atggccgtgt tggtattttc
     1261 cccaagtgct ttgtagtccc agctgccacc tgtgtggaag ccctgcctgt acctgaaccc
     1321 cagccaggag aacagcacta gcaataaata ccgtgacaaa accagcttta atttaaac
//
