LOCUS       XM_008759643            4117 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus NADPH oxidase 4 (Nox4), transcript
            variant X3, mRNA.
ACCESSION   XM_008759643
VERSION     XM_008759643.3
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051336.1) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Feb 22, 2024 this sequence was replaced by
            XM_008759643.4.
            
            On Jan 21, 2021 this sequence version replaced XM_008759643.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4117
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..4117
                     /gene="Nox4"
                     /note="NADPH oxidase 4; Derived by automated computational
                     analysis using gene prediction method: Gnomon. Supporting
                     evidence includes similarity to: 10 ESTs, 1 long SRA read,
                     1 Protein, and 95% coverage of the annotated genomic
                     feature by RNAseq alignments"
                     /db_xref="GeneID:85431"
                     /db_xref="RGD:620600"
     CDS             407..2278
                     /gene="Nox4"
                     /codon_start=1
                     /product="NADPH oxidase 4 isoform X3"
                     /protein_id="XP_008757865.1"
                     /db_xref="GeneID:85431"
                     /db_xref="RGD:620600"
                     /translation="MALSWRSWLANEGVKHLCLLVWLSLNVLLFWKTFLLYNQGPEYY
                     YIHQMLGLGLCLSRASASVLNLNCSLILLPMCRTVLAYLRGSQKVPSRRTRRLLDKSK
                     TLHITCGITICIFSGVHVAAHLVNALNFSVNYSEHFLALNAARYQNEDPRKLLFTTVP
                     GLTGVCMVVVLFLMVTASTYAIRVSNYDIFWYTHNLFFVFYMLLLLHVSGGLLKYQTN
                     LDTHPPGCISLNRTPSQNMSIADYVSEHFHGSLPGGFSKLEDHYQKTLVKICLEEPKF
                     QAHFPQTWIWISGPLCLYCAERLYRCIRSNKPVTIISVINHPSDVMELRMIKENFKAR
                     PGQYIILHCPSVSALENHPFTLTMIMSSVWVCQKRWQLWPGTVYIHTSILCGDAARHD
                     YASKIHHALLLCPTETKATFGVHFKVVGDWTERFRDLLLPPSSQDSEILPFIQSRNYP
                     KLYIDGPFGSPFEESLNYEVSLCVAGGIGVTPFASILNTLLDDWKPYKLRRLYFIWVC
                     RDIQSFQWFADLLYVLHNKFWQENRPDFVNIQLYLSQTDGIQKIIGEKYHTLNSRLFI
                     GRPRWKLLFDEIAKCNRGKTVGVFCCGPSSISKTLHNLSNRNNSYGTKFEYNKESFS"
ORIGIN      
        1 tggtgtgtgc gccccgggat gcaaagagcg tccccctctt ccgattctca tcctcacatc
       61 tgggggttgt ctgcagctgg gcaggcccgg ttggaggctg caggggacgc ctccaccttc
      121 ccacccggga catcctgaac ggcggccaca acaacaggct cgcgcgagac aaaggggctg
      181 gcgcggggcg gcgcgcaggg ccagggggcg tggggaggca agggagcagc tcggtgggag
      241 ccagggcgga gatctcctgc ctggcctcta gactcggccc agcctttgac cctcggtccc
      301 ccgccactgc tctgctggcg gctacccggg aaccggtgcc ccggccacag ctcgctcctt
      361 tccgtcccaa gcaccgagcg gagcgcagca cccccgcgcc ggcggtatgg cgctgtcctg
      421 gaggagctgg ctggccaacg aaggggttaa acacctctgt ctgcttgttt ggctgtccct
      481 aaatgtcctg cttttctgga aaaccttcct gctgtacaac caagggccag aatactacta
      541 catccaccag atgttgggcc taggattgtg tttgagcaga gcttctgcat ctgtcctgaa
      601 cctcaactgc agcctgatcc ttttacccat gtgccgcaca gtcctggctt accttcgcgg
      661 atcacagaag gtccctagca ggagaacaag aagattgttg gacaaaagca agactctaca
      721 tatcacctgt ggcataacta tttgtatttt ctcaggtgtg catgtagctg cccacttggt
      781 gaacgccctg aacttctcag tgaactatag tgaacatttc cttgcactga atgcagcaag
      841 ataccagaat gaggatccca gaaagcttct cttcacaact gttccgggcc tgacaggtgt
      901 ctgcatggtg gtggtattgt tcctcatggt tacagcttct acctatgcaa taagagtttc
      961 taattatgat atcttctggt atactcacaa cctcttcttt gtcttctaca tgctgctgct
     1021 gctgcatgtt tcgggtggct tgttgaagta tcaaaccaat ttagacactc accctcctgg
     1081 ctgtatcagt cttaaccgga ccccatctca gaatatgtcc atagcagact acgtctcaga
     1141 acattttcat ggatctttgc ctggagggtt ttcaaaatta gaagatcatt accagaaaac
     1201 actggtgaag atttgcctgg aagaacccaa gttccaagct catttcccac agacctggat
     1261 ttggatttct ggacctttgt gcctatactg tgctgagaga ctttaccgat gcatccggag
     1321 caacaaacct gtcaccatta tctcagtaat caatcatccc tcagatgtca tggaactccg
     1381 tatgatcaaa gaaaacttta aagcaagacc tggccagtat attattctac attgtcccag
     1441 tgtatcagca ttagaaaacc acccatttac tctcacaatg ataatgagct ctgtttgggt
     1501 ctgtcagaaa agatggcagc tctggcccgg cacagtatac atacacactt ccattctgtg
     1561 tggtgatgca gcaagacatg actatgcttc caagattcac catgccctct tactgtgtcc
     1621 tactgaaacc aaagcaacat ttggtgtcca ctttaaagta gtaggagact ggacagaaag
     1681 attccgagat ttactactgc ctccatcaag ccaagattct gagattctgc ccttcattca
     1741 atctagaaac taccccaagt tatacatcga tggcccattt ggaagtccat ttgaggagtc
     1801 actgaactat gaagttagtc tgtgtgtggc tggaggcatt ggggtcactc cgtttgcatc
     1861 gatactaaac actctactgg atgactggaa accatacaag ctaagaagac tgtattttat
     1921 ctgggtctgc agagacatcc aatcattcca gtggtttgca gacttgctct atgtgctgca
     1981 taacaagttt tggcaagaaa acagacctga ctttgtgaac atccagctgt acctcagtca
     2041 aacagatggg atacagaaga taattggaga aaaataccac acattgaatt ctagactttt
     2101 tattgggcgt cctcggtgga agcttttatt tgatgaaata gcaaaatgta acagagggaa
     2161 aacagttgga gttttctgct gtggacccag ttctatttcc aagactcttc ataatttgag
     2221 taaccggaac aactcatatg ggacaaaatt tgaatacaat aaagaatctt tcagctaaaa
     2281 ccttaggaga ctactgggac tctaaaaaag gaacaagtgc aatttctaag acttagagac
     2341 tcggctgaat cagacagcta tgctatgcca aagaatatca aagttttgct atttatgatt
     2401 atttaaaatg agaattcaaa aagtatggca aaaatgacat ggttaatctg caagccaaag
     2461 gggccctgaa gaatatttga tgtggtgact cacatattga tgggcaaatt aaaagaatgc
     2521 tgttagatgc acactgttga tttttatggg aaattcaaga actctctaat gaggagctga
     2581 actcactcac tctgaagctg atagccacag ccctctttaa attgttttca gtcgaacagg
     2641 ttcaaagatt gaacaaaatt aaaaattcat tgaaactcag actccatttt ctaccttctg
     2701 aataagtgga gtagctttaa tttagatggg ctccaggcaa acacttggag gttgaaactg
     2761 tagcacaaaa ctttatatca atacgggtag ttcatgtctg ctgcttcact actgactctc
     2821 atgccgccct gtagcgttcc tagtctacat gctctcaagt cttatgcccc tgtggatgtc
     2881 tcactgactt tcgtattttt gcatcttacc ttctgtgtag gaaaatctgc tccccctcag
     2941 ccaacctttg acacaatgaa acaatagaac tgtttgatga caaatttgtt caacttagtg
     3001 ctatggcgta gtaatgaaaa ctgagagcag agccccttaa ggtgctgttt taagtttatg
     3061 cttagacacc aaagagcttt gtatcttgca cggaacacgg aagcacagga cctctctcca
     3121 ctgactccct ttgttttcag acaagagata tggaattcat gtacctgaaa tggtaccctg
     3181 ctttgctttc tacaaaagta gaacttcaaa ttttagttta gaatcactaa tattattttt
     3241 caccgtttga aaccatggtg agttattagt tttaagttcc ctgttcatgt gatccaatca
     3301 gtgtatgacc tctcactatt taatattccc gaatcagaag gaaaatctac attgctaact
     3361 taataaagaa gatattcata cagtttatcc actttagttt ggtagataac tattaatgct
     3421 atcaaataga acagattgct gaaattcata ccttgcctga ttcttgttaa tcttttgtgc
     3481 atcacatgat aacgataaat gccattatta tttggctttc atgtgattca ccgataaata
     3541 gtcaagcaca ctacaacatc tagcaccaac gaccacattt atatttagat acacatattg
     3601 ttcttttatc cttggaacac tttcttatcc ctcctacggg caacgtgcaa tgctcctgta
     3661 gataaaactg tggagacaaa taaactacga catctttgca atactgtcta gatgaaaagg
     3721 cttttcacaa aacacatatg gcaaagaact cataaaaaag aaacttgagt tggtccaagc
     3781 ttaatgtgca atactgactt cttactgatt ataacgtatt catatgactg actatgagaa
     3841 tccatcagat ttcggtaatt caggtcaaac ttttaaaaaa caaagatgat atttcagact
     3901 tgcttgctag gtggagtgaa cttccttgcc tagtctaaat tctggcacat gttcaagcat
     3961 ctgcttgtta aacatggttt atgttagaac aggaataagt taaagctttc tcacacatag
     4021 agaagacagc tttcctttga aagattgtat ggtggcagat ttttctgtgt aagccctaaa
     4081 tcgctaattt tgatggcaat aaatactaaa attaaaa
//
