LOCUS       NM_001106260            1442 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus nitric oxide synthase interacting protein
            (Nosip), mRNA.
ACCESSION   NM_001106260 XM_001078785 XM_214926
VERSION     NM_001106260.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1442)
  AUTHORS   Yu,X., Zhong,Y., Zhu,Z., Wu,T., Shen,A. and Huang,Y.
  TITLE     Increased expression of nitric oxide synthase interacting protein
            (NOSIP) following traumatic spinal cord injury in rats
  JOURNAL   J Mol Histol 43 (6), 661-668 (2012)
   PUBMED   23135205
  REMARK    GeneRIF: Data suggested that NOSIP may play an important roles in
            astrogliogenesis after a spinal cord injury.
REFERENCE   2  (bases 1 to 1442)
  AUTHORS   Castello,A., Fischer,B., Eichelbaum,K., Horos,R., Beckmann,B.M.,
            Strein,C., Davey,N.E., Humphreys,D.T., Preiss,T., Steinmetz,L.M.,
            Krijgsveld,J. and Hentze,M.W.
  TITLE     Insights into RNA biology from an atlas of mammalian mRNA-binding
            proteins
  JOURNAL   Cell 149 (6), 1393-1406 (2012)
   PUBMED   22658674
REFERENCE   3  (bases 1 to 1442)
  AUTHORS   Dreyer,J., Schleicher,M., Tappe,A., Schilling,K., Kuner,T.,
            Kusumawidijaja,G., Muller-Esterl,W., Oess,S. and Kuner,R.
  TITLE     Nitric oxide synthase (NOS)-interacting protein interacts with
            neuronal NOS and regulates its distribution and activity
  JOURNAL   J Neurosci 24 (46), 10454-10465 (2004)
   PUBMED   15548660
REFERENCE   4  (bases 1 to 1442)
  AUTHORS   Dedio,J., Konig,P., Wohlfart,P., Schroeder,C., Kummer,W. and
            Muller-Esterl,W.
  TITLE     NOSIP, a novel modulator of endothelial nitric oxide synthase
            activity
  JOURNAL   FASEB J 15 (1), 79-89 (2001)
   PUBMED   11149895
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473979.2.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_214926.3, XM_001078785.1.
            
            ##Evidence-Data-START##
            CDS exon combination :: FQ216351.1 [ECO:0000331]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..1442
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q22"
     gene            1..1442
                     /gene="Nosip"
                     /note="nitric oxide synthase interacting protein"
                     /db_xref="GeneID:292894"
                     /db_xref="RGD:1309992"
     exon            1..52
                     /gene="Nosip"
                     /inference="alignment:Splign:2.1.0"
     CDS             53..958
                     /gene="Nosip"
                     /EC_number="2.3.2.27"
                     /codon_start=1
                     /product="nitric oxide synthase-interacting protein"
                     /protein_id="NP_001099730.1"
                     /db_xref="GeneID:292894"
                     /db_xref="RGD:1309992"
                     /translation="MTRHGKNCTAGAVYTYHEKKKDTAASGYGTQNIRLSRDAVKDFD
                     CCCLSLQPCHDPVVTPDGYLYEREAILEYILHQKREIARQMKAYEKQRGARREEQKEL
                     QRAAAQDQVRGFLEKESAIVSRPLNPFMPKAATLPNTDGEQPGPSVGPLGKDKDKALP
                     SFWIPSLTPEAKATKLEKPSRTVTCPMSGKPLRMSDLTSVRFTQLDDSVDRVGLITRS
                     ERYVCAVTRDSLSNATPCAVLRPSGAVVTLECVEKLIRKDMVDPVNGDTLTERDIIVL
                     QRGGTGFAGSGVKLQAEMSRPVMQA"
     exon            53..122
                     /gene="Nosip"
                     /inference="alignment:Splign:2.1.0"
     exon            123..228
                     /gene="Nosip"
                     /inference="alignment:Splign:2.1.0"
     exon            229..310
                     /gene="Nosip"
                     /inference="alignment:Splign:2.1.0"
     exon            311..470
                     /gene="Nosip"
                     /inference="alignment:Splign:2.1.0"
     exon            471..589
                     /gene="Nosip"
                     /inference="alignment:Splign:2.1.0"
     exon            590..777
                     /gene="Nosip"
                     /inference="alignment:Splign:2.1.0"
     exon            778..886
                     /gene="Nosip"
                     /inference="alignment:Splign:2.1.0"
     exon            887..1442
                     /gene="Nosip"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tccggttcgg gacacagttg aagcaacgac aggacggata gtcgtttttg agatgacaag
       61 gcatggcaag aactgcactg caggggctgt ctacacctac cacgaaaaga agaaggacac
      121 agcggcctca ggctatggga cccagaacat tcgactgagc cgggatgctg tgaaggactt
      181 tgactgctgc tgtctctctc tgcagccctg ccatgaccct gtggtcaccc cagacggcta
      241 cctgtatgaa agggaggcaa tcctggagta catcctacac cagaagagag agattgcccg
      301 gcagatgaag gcctatgaga agcagcgagg agcccggaga gaagagcaga aagagctgca
      361 gcgagctgca gcacaggacc aagttcgagg cttcctggag aaggagtcag ccattgtgag
      421 ccggcccctc aaccccttca tgcccaaggc tgccaccttg cccaacacag atggtgaaca
      481 gccagggccc agtgtgggtc ccctaggcaa ggacaaggac aaagcactac ccagcttctg
      541 gattccctca ctaacgcccg aggcaaaggc caccaagctg gaaaagccgt cccgcacggt
      601 gacctgcccg atgtctggga agccactgcg catgtcggac ctgacgtcag tgcgcttcac
      661 acagctggac gactctgtgg accgagtggg gctcatcacg cgcagtgagc gctacgtgtg
      721 cgcagtgacc cgagacagcc tgagcaacgc cacgccgtgt gcggtgctgc ggccctccgg
      781 ggctgtggtc accctggagt gtgtggagaa actgatccgg aaggacatgg tggaccccgt
      841 gaacggagat acgctgacgg agcgggacat catcgtgctg cagcggggtg gcacaggctt
      901 tgcaggctcc ggagtgaagc tacaggcaga aatgtcccgg ccagtgatgc aggcctgagc
      961 cgtgacctaa taaacttgga cgtgaacagg ctggatgtgt ggcccttcat tgtaggcagg
     1021 ggctacagaa agagtggacc caaggtgtgg catccactca ggatctctaa gctcctggag
     1081 gtttactcag tcactcatga gcgtgcagaa accctggcag catgaacctg tcagtctccc
     1141 ctgcctcagt caggacctgg aagaaggcgc cctgtccagg aagtacaggc ctcaggataa
     1201 cactcccagg cctgctgcct gcgagacccc atagaccttt ccccaccatg cgcccttccc
     1261 ccaaggatcc cctgcagacc cggtacacac cgcacactac tccgcgtgca cacttagctt
     1321 cttcacctct ttccctcaac gcccagagtg tctctcaaga gctagcttcc ctgaggatgg
     1381 acagctttcc tccgtgcctc cccaaacccg aaacctgttc acaagcaaca cagaacaccc
     1441 tc
//
