LOCUS       NM_001025732            1936 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus NOP56 ribonucleoprotein (Nop56), mRNA.
ACCESSION   NM_001025732 XM_342517
VERSION     NM_001025732.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1936)
  AUTHORS   Guo,Z., Neilson,L.J., Zhong,H., Murray,P.S., Zanivan,S. and
            Zaidel-Bar,R.
  TITLE     E-cadherin interactome complexity and robustness resolved by
            quantitative proteomics
  JOURNAL   Sci Signal 7 (354), rs7 (2014)
   PUBMED   25468996
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1936)
  AUTHORS   Cowling,V.H., Turner,S.A. and Cole,M.D.
  TITLE     Burkitt's lymphoma-associated c-Myc mutations converge on a
            dramatically altered target gene response and implicate Nol5a/Nop56
            in oncogenesis
  JOURNAL   Oncogene 33 (27), 3519-3527 (2014)
   PUBMED   24013231
  REMARK    GeneRIF: Nol5a expands the link between Myc-induced regulation of
            nucleolar target genes
REFERENCE   3  (bases 1 to 1936)
  AUTHORS   Brandis,K.A., Gale,S., Jinn,S., Langmade,S.J., Dudley-Rucker,N.,
            Jiang,H., Sidhu,R., Ren,A., Goldberg,A., Schaffer,J.E. and Ory,D.S.
  TITLE     Box C/D small nucleolar RNA (snoRNA) U60 regulates intracellular
            cholesterol trafficking
  JOURNAL   J Biol Chem 288 (50), 35703-35713 (2013)
   PUBMED   24174535
REFERENCE   4  (bases 1 to 1936)
  AUTHORS   Baltz,A.G., Munschauer,M., Schwanhausser,B., Vasile,A.,
            Murakawa,Y., Schueler,M., Youngs,N., Penfold-Brown,D., Drew,K.,
            Milek,M., Wyler,E., Bonneau,R., Selbach,M., Dieterich,C. and
            Landthaler,M.
  TITLE     The mRNA-bound proteome and its global occupancy profile on
            protein-coding transcripts
  JOURNAL   Mol Cell 46 (5), 674-690 (2012)
   PUBMED   22681889
REFERENCE   5  (bases 1 to 1936)
  AUTHORS   Castello,A., Fischer,B., Eichelbaum,K., Horos,R., Beckmann,B.M.,
            Strein,C., Davey,N.E., Humphreys,D.T., Preiss,T., Steinmetz,L.M.,
            Krijgsveld,J. and Hentze,M.W.
  TITLE     Insights into RNA biology from an atlas of mammalian mRNA-binding
            proteins
  JOURNAL   Cell 149 (6), 1393-1406 (2012)
   PUBMED   22658674
REFERENCE   6  (bases 1 to 1936)
  AUTHORS   Watkins,N.J. and Bohnsack,M.T.
  TITLE     The box C/D and H/ACA snoRNPs: key players in the modification,
            processing and the dynamic folding of ribosomal RNA
  JOURNAL   Wiley Interdiscip Rev RNA 3 (3), 397-414 (2012)
   PUBMED   22065625
  REMARK    Review article
REFERENCE   7  (bases 1 to 1936)
  AUTHORS   Ghosh,D., Lippert,D., Krokhin,O., Cortens,J.P. and Wilkins,J.A.
  TITLE     Defining the membrane proteome of NK cells
  JOURNAL   J Mass Spectrom 45 (1), 1-25 (2010)
   PUBMED   19946888
REFERENCE   8  (bases 1 to 1936)
  AUTHORS   McKeegan,K.S., Debieux,C.M., Boulon,S., Bertrand,E. and
            Watkins,N.J.
  TITLE     A dynamic scaffold of pre-snoRNP factors facilitates human box C/D
            snoRNP assembly
  JOURNAL   Mol Cell Biol 27 (19), 6782-6793 (2007)
   PUBMED   17636026
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC099149.1.
            
            On Jul 27, 2005 this sequence version replaced XM_342517.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC099149.1, SRR8487226.101344.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1936
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="3"
                     /map="3q36"
     gene            1..1936
                     /gene="Nop56"
                     /gene_synonym="Nol5a"
                     /note="NOP56 ribonucleoprotein"
                     /db_xref="GeneID:362214"
                     /db_xref="RGD:1308892"
     exon            1..59
                     /gene="Nop56"
                     /gene_synonym="Nol5a"
                     /inference="alignment:Splign:2.1.0"
     CDS             57..1823
                     /gene="Nop56"
                     /gene_synonym="Nol5a"
                     /note="nucleolar protein 5A; NOP56 ribonucleoprotein
                     homolog"
                     /codon_start=1
                     /product="nucleolar protein 56"
                     /protein_id="NP_001020903.1"
                     /db_xref="GeneID:362214"
                     /db_xref="RGD:1308892"
                     /translation="MVLLHVLFEHAVGYALLALKEVEEISLLLPQVEECVLNLGKFHN
                     VVRLVAFCPFSSSQVALENANAVSEGVVHEDLRLLLETYLPSKKKKVLLGVGDPKIGA
                     AIQEELGYNCQTGGVIAEILRGVRLHFHNLVKGLTDLSACKAQLGLGHSYSRAKVKFN
                     VNRVDNMIIQSISLLDQLDKDINTFSMRVREWYGYHFPELVKIINDNATYCRLAQFIG
                     NRRELNEEKLEKLEEITMDGAKAKAILDASRSSMGMDISAIDLINIESFSSRVVSLSE
                     YRQSLHNYLRSKMSQVAPSLSALIGEAVGARLIAHAGSLTNLAKYPASTVQILGAEKA
                     LFRALKTRGNTPKYGLIFHSTFIGRAAAKNKGRISRYLANKCSIASRIDCFSEVPTSV
                     FGEKLREQVEERLSFYETGEIPRKNLDVMKEAVVQAEEAAAEITRKLEKQEKKRLKKE
                     KKRLAALALASSENSSTPEECEEVNEKPKKKKLKPQETLQENGMEDPPVSLPKTKKKK
                     AFPKEELASDLEEMATSSISVPKKKKSLPKEEVASEPEEAASPITPKKKRKFSEEPEA
                     AASCTKSSTKKKKKSQKAREED"
     exon            60..149
                     /gene="Nop56"
                     /gene_synonym="Nol5a"
                     /inference="alignment:Splign:2.1.0"
     exon            150..264
                     /gene="Nop56"
                     /gene_synonym="Nol5a"
                     /inference="alignment:Splign:2.1.0"
     exon            265..426
                     /gene="Nop56"
                     /gene_synonym="Nol5a"
                     /inference="alignment:Splign:2.1.0"
     exon            427..625
                     /gene="Nop56"
                     /gene_synonym="Nol5a"
                     /inference="alignment:Splign:2.1.0"
     exon            626..813
                     /gene="Nop56"
                     /gene_synonym="Nol5a"
                     /inference="alignment:Splign:2.1.0"
     exon            814..965
                     /gene="Nop56"
                     /gene_synonym="Nol5a"
                     /inference="alignment:Splign:2.1.0"
     exon            966..1066
                     /gene="Nop56"
                     /gene_synonym="Nol5a"
                     /inference="alignment:Splign:2.1.0"
     exon            1067..1215
                     /gene="Nop56"
                     /gene_synonym="Nol5a"
                     /inference="alignment:Splign:2.1.0"
     exon            1216..1337
                     /gene="Nop56"
                     /gene_synonym="Nol5a"
                     /inference="alignment:Splign:2.1.0"
     exon            1338..1472
                     /gene="Nop56"
                     /gene_synonym="Nol5a"
                     /inference="alignment:Splign:2.1.0"
     exon            1473..1912
                     /gene="Nop56"
                     /gene_synonym="Nol5a"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gttccgcgcg ccagagcgcg ctacccgcat tgcgagctgg gcacggagca ggcgccatgg
       61 ttctgctgca cgtgctcttc gagcatgcgg tcggctacgc gctgttagcg ctgaaggaag
      121 tagaggagat cagcttgctg ttgccgcagg tggaggagtg tgtgcttaac cttggcaaat
      181 tccacaatgt cgttcgtctg gtggcctttt gccccttttc ttcatcccag gttgccttgg
      241 aaaatgctaa tgctgtgtct gaaggtgttg ttcatgagga cctccgcctg ctcctggaga
      301 catacctgcc atctaaaaag aagaaagtac ttctgggggt cggagacccc aagatcggtg
      361 ctgctataca ggaagagttg gggtacaact gccagactgg tggtgtgata gctgagatcc
      421 ttcgaggggt tcgtctgcat ttccataacc tggtgaaggg tctgacagat ctttctgctt
      481 gtaaagccca gctagggctg ggacacagct attctcgtgc caaagttaag tttaatgtga
      541 accgggtgga caacatgatc attcagtcta taagccttct ggaccaactg gataaagata
      601 tcaatacctt ctccatgcgt gtcagggagt ggtatgggta ccactttcca gagctggtga
      661 agattatcaa cgacaatgct acatactgtc gcctggctca gttcatcggg aaccgcaggg
      721 agctaaatga agaaaagtta gagaagctgg aagaaattac aatggatgga gccaaggcta
      781 aggccattct ggatgcctct cggtcctcca tgggcatgga catatctgct atcgacttga
      841 taaacatcga gagcttctcc agtcgtgtgg tgtctttgtc agagtatcgc cagagcctac
      901 acaattacct tcgctccaag atgagccaag tagcccccag cctgtcagcc ttaattgggg
      961 aagcggtagg tgcacgtctc attgcccatg ctggcagcct caccaacctg gccaagtacc
     1021 cagcatccac agtgcagatc cttggggctg aaaaggccct gttcagagcc ctgaagacaa
     1081 ggggtaacac accaaaatac ggactcattt ttcattccac tttcattggc cgagcagctg
     1141 caaagaacaa aggccgtatc tcccgatacc tagcaaacaa atgcagtatt gcctcaagaa
     1201 ttgattgctt ctctgaggtc cccacaagtg tatttgggga gaaactccgg gaacaagttg
     1261 aagagcggct ttctttctat gagactggag agattccacg gaagaacctg gatgtcatga
     1321 aagaagctgt ggtacaggca gaggaagcgg ctgctgaaat aaccagaaag ctggaaaaac
     1381 aggagaagaa acgcttgaag aaggaaaaga agcgactggc tgcactggcc ctggcctctt
     1441 cagaaaacag tagtactccg gaagagtgtg aggaggtaaa tgaaaaacct aagaagaaaa
     1501 agctaaaacc ccaggaaacc ctacaggaaa atggaatgga agacccacct gtctctttgc
     1561 ctaaaaccaa gaaaaagaaa gcttttccca aggaggagtt ggccagtgat cttgaagaga
     1621 tggctactag cagcataagt gttcctaaga aaaagaagtc cttacctaaa gaggaagtgg
     1681 ccagtgaacc cgaagaggca gcgagcccca tcacccctaa gaagaaaagg aaattttctg
     1741 aggagcctga ggctgctgca agctgcacaa agagcagcac aaagaaaaag aaaaagtcgc
     1801 agaaggcccg ggaggaggat tagaatggac ctgcttggtg ggaggggcat actttatggt
     1861 ggcagttcct cctgcccatg ataaacccca ataaaaacgc aaaaccagat aaaaaaaaaa
     1921 aaaaaaaaaa aaaaaa
//
