LOCUS       NM_022869               3610 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus nucleolar and coiled-body phosphoprotein 1
            (Nolc1), mRNA.
ACCESSION   NM_022869
VERSION     NM_022869.2
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3610)
  AUTHORS   Werner,A., Iwasaki,S., McGourty,C.A., Medina-Ruiz,S.,
            Teerikorpi,N., Fedrigo,I., Ingolia,N.T. and Rape,M.
  TITLE     Cell-fate determination by ubiquitin-dependent regulation of
            translation
  JOURNAL   Nature 525 (7570), 523-527 (2015)
   PUBMED   26399832
REFERENCE   2  (bases 1 to 3610)
  AUTHORS   Baltz,A.G., Munschauer,M., Schwanhausser,B., Vasile,A.,
            Murakawa,Y., Schueler,M., Youngs,N., Penfold-Brown,D., Drew,K.,
            Milek,M., Wyler,E., Bonneau,R., Selbach,M., Dieterich,C. and
            Landthaler,M.
  TITLE     The mRNA-bound proteome and its global occupancy profile on
            protein-coding transcripts
  JOURNAL   Mol Cell 46 (5), 674-690 (2012)
   PUBMED   22681889
REFERENCE   3  (bases 1 to 3610)
  AUTHORS   Castello,A., Fischer,B., Eichelbaum,K., Horos,R., Beckmann,B.M.,
            Strein,C., Davey,N.E., Humphreys,D.T., Preiss,T., Steinmetz,L.M.,
            Krijgsveld,J. and Hentze,M.W.
  TITLE     Insights into RNA biology from an atlas of mammalian mRNA-binding
            proteins
  JOURNAL   Cell 149 (6), 1393-1406 (2012)
   PUBMED   22658674
REFERENCE   4  (bases 1 to 3610)
  AUTHORS   Lee,H.C., Yamanouchi,K. and Nishihara,M.
  TITLE     Effects of perinatal exposure to phthalate/adipate esters on
            hypothalamic gene expression and sexual behavior in rats
  JOURNAL   J Reprod Dev 52 (3), 343-352 (2006)
   PUBMED   16493179
  REMARK    GeneRIF: inappropriate expression of grn and/or p130 genes in the
            brains of male and female neonatal rats by perinatal exposure to
            phthalate/adipate esters may exert permanent effects on the
            hypothalamus, thereby decreasing sexual behavior after maturation
REFERENCE   5  (bases 1 to 3610)
  AUTHORS   Moser,K. and White,F.M.
  TITLE     Phosphoproteomic analysis of rat liver by high capacity IMAC and
            LC-MS/MS
  JOURNAL   J Proteome Res 5 (1), 98-104 (2006)
   PUBMED   16396499
REFERENCE   6  (bases 1 to 3610)
  AUTHORS   Yang,Y., Isaac,C., Wang,C., Dragon,F., Pogacic,V. and Meier,U.T.
  TITLE     Conserved composition of mammalian box H/ACA and box C/D small
            nucleolar ribonucleoprotein particles and their interaction with
            the common factor Nopp140
  JOURNAL   Mol Biol Cell 11 (2), 567-577 (2000)
   PUBMED   10679015
REFERENCE   7  (bases 1 to 3610)
  AUTHORS   Warskulat,U., Hammermann,R. and Haussinger,D.
  TITLE     Anisoosmotic regulation of the Nopp140 mRNA in H4IIE rat hepatoma
            cells and primary hepatocytes
  JOURNAL   FEBS Lett 452 (3), 259-262 (1999)
   PUBMED   10386602
REFERENCE   8  (bases 1 to 3610)
  AUTHORS   Miau,L.H., Chang,C.J., Shen,B.J., Tsai,W.H. and Lee,S.C.
  TITLE     Identification of heterogeneous nuclear ribonucleoprotein K (hnRNP
            K) as a repressor of C/EBPbeta-mediated gene activation
  JOURNAL   J Biol Chem 273 (17), 10784-10791 (1998)
   PUBMED   9553145
REFERENCE   9  (bases 1 to 3610)
  AUTHORS   Miau,L.H., Chang,C.J., Tsai,W.H. and Lee,S.C.
  TITLE     Identification and characterization of a nucleolar phosphoprotein,
            Nopp140, as a transcription factor
  JOURNAL   Mol Cell Biol 17 (1), 230-239 (1997)
   PUBMED   8972203
REFERENCE   10 (bases 1 to 3610)
  AUTHORS   Meier,U.T. and Blobel,G.
  TITLE     Nopp140 shuttles on tracks between nucleolus and cytoplasm
  JOURNAL   Cell 70 (1), 127-138 (1992)
   PUBMED   1623516
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000001.1.
            
            On Nov 27, 2020 this sequence version replaced NM_022869.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: M94287.1, SRR26643295.6931.1
                                           [ECO:0000332]
            RNAseq introns              :: partial sample support SAMEA5760383,
                                           SAMEA5760386 [ECO:0000350]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-172               JAXUCZ010000001.1  254870359-254870530
            173-228             JAXUCZ010000001.1  254873219-254873274
            229-368             JAXUCZ010000001.1  254873386-254873525
            369-499             JAXUCZ010000001.1  254873630-254873760
            500-680             JAXUCZ010000001.1  254874572-254874752
            681-805             JAXUCZ010000001.1  254876765-254876889
            806-941             JAXUCZ010000001.1  254877014-254877149
            942-1070            JAXUCZ010000001.1  254877711-254877839
            1071-1181           JAXUCZ010000001.1  254877997-254878107
            1182-1808           JAXUCZ010000001.1  254878220-254878846
            1809-1915           JAXUCZ010000001.1  254879002-254879108
            1916-2008           JAXUCZ010000001.1  254879251-254879343
            2009-3610           JAXUCZ010000001.1  254879468-254881069
FEATURES             Location/Qualifiers
     source          1..3610
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q54"
     gene            1..3610
                     /gene="Nolc1"
                     /gene_synonym="Nopp140"
                     /note="nucleolar and coiled-body phosphoprotein 1"
                     /db_xref="GeneID:64896"
                     /db_xref="RGD:621578"
     exon            1..172
                     /gene="Nolc1"
                     /gene_synonym="Nopp140"
                     /inference="alignment:Splign:2.1.0"
     CDS             53..2167
                     /gene="Nolc1"
                     /gene_synonym="Nopp140"
                     /note="nucleolar 130 kDa protein; 140 kDa nucleolar
                     phosphoprotein; nucleolar phosphoprotein p130; nucleolar
                     phosphoprotein 140"
                     /codon_start=1
                     /product="nucleolar and coiled-body phosphoprotein 1"
                     /protein_id="NP_074060.2"
                     /db_xref="GeneID:64896"
                     /db_xref="RGD:621578"
                     /translation="MADTGLRRVVPSDLYPLVLGFLRDNQLSEVASKFAKATGATQQD
                     ANASSLLDIYSFWLKSTKAPKVKLQSNGPVAKKAKKETSSSDSSEDSSEEEDKAQVPT
                     QKAAAPAKRASLPQHAGKAAAKASESSSSEESSEEEEEEDKKKKPVQQKAVKPQAKAV
                     RPPPKKAESSESESDSSSEDEAPQTQKPKAAATAAKAPTKAQTKAPAKPGPPAKAQPK
                     AANGKAGSSSSSSSSSSSDDSEEEKKAAAPLKKTAPKKQVVAKAPVKVTAAPTQKSSS
                     SEDSSSEEEEEQKKPMKKKAGPYSSVPPPSVSLSKKSVGAQSPKKAAAQTQPADSSAD
                     SSEESDSSSEEEKKTPAKTVVSKTPAKPAPVKKKAESSSDSSDSDSSEDEAPAKPVSA
                     TKSPLSKPAVTPKPPAAKAVATPKQPAGSGQKPQSRKADSSSSEEESSSSEEEATKKS
                     VTTPKARVTAKAAPSLPAKQAPRAGGDSSSDSESSSSEEEKKTPPKPPAKKKAAGAAV
                     PKPTPVKKAAAESSSSSSSSEDSSEEEKKKPKSKATPKPQAGKANGVPASQNGKAGKE
                     SEEEEEDTEQNKKAAGTKPGSGKKRKHNETADEAATPQSKKVKLQTPNTFPKRKKGEK
                     RASSPFRRVREEEIEVDSRVADNSFDAKRGAAGDWGERANQVLKFTKGKSFRHEKTKK
                     KRGSYRGGSISVQVNSVKFDSE"
     exon            173..228
                     /gene="Nolc1"
                     /gene_synonym="Nopp140"
                     /inference="alignment:Splign:2.1.0"
     exon            229..368
                     /gene="Nolc1"
                     /gene_synonym="Nopp140"
                     /inference="alignment:Splign:2.1.0"
     exon            369..499
                     /gene="Nolc1"
                     /gene_synonym="Nopp140"
                     /inference="alignment:Splign:2.1.0"
     exon            500..680
                     /gene="Nolc1"
                     /gene_synonym="Nopp140"
                     /inference="alignment:Splign:2.1.0"
     exon            681..805
                     /gene="Nolc1"
                     /gene_synonym="Nopp140"
                     /inference="alignment:Splign:2.1.0"
     exon            806..941
                     /gene="Nolc1"
                     /gene_synonym="Nopp140"
                     /inference="alignment:Splign:2.1.0"
     exon            942..1070
                     /gene="Nolc1"
                     /gene_synonym="Nopp140"
                     /inference="alignment:Splign:2.1.0"
     exon            1071..1181
                     /gene="Nolc1"
                     /gene_synonym="Nopp140"
                     /inference="alignment:Splign:2.1.0"
     exon            1182..1808
                     /gene="Nolc1"
                     /gene_synonym="Nopp140"
                     /inference="alignment:Splign:2.1.0"
     exon            1809..1915
                     /gene="Nolc1"
                     /gene_synonym="Nopp140"
                     /inference="alignment:Splign:2.1.0"
     exon            1916..2008
                     /gene="Nolc1"
                     /gene_synonym="Nopp140"
                     /inference="alignment:Splign:2.1.0"
     exon            2009..3610
                     /gene="Nolc1"
                     /gene_synonym="Nopp140"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gttcttcagt cgtaccgcgt gcgcaacggt agtgacgcgt ttaacccgga gtatggcgga
       61 taccggcttg cgccgcgtgg ttcccagcga cctttatccc cttgtgctcg gctttctgcg
      121 agataaccag ctctcagagg tggccagtaa atttgcaaaa gcgacaggcg ctacacagca
      181 ggacgccaat gcctcttccc tcttggacat ttatagcttt tggctcaagt ccaccaaagc
      241 cccgaaggtg aaactgcagt caaatggacc agtggccaaa aaggctaaga aagagacttc
      301 atccagtgac agcagtgagg acagcagtga ggaagaggac aaagcccaag ttcccacaca
      361 gaaggctgcc gcccctgcca agcgagccag tttgcctcag catgctggga aagcagcagc
      421 caaagcttca gagagcagca gtagtgaaga gtccagtgag gaagaggagg aggaggacaa
      481 aaagaaaaag cctgtccagc agaaagcagt taagccccaa gccaaggcag tcagacctcc
      541 tccgaagaag gcagagagct ctgagtccga gtctgactca agctcagagg atgaagcacc
      601 acagacccag aagccaaagg cagctgctac ggcagctaaa gccccgacta aagcccagac
      661 taaagcccca gccaaaccag gtccaccagc gaaagcacag cctaaagcag ccaatggcaa
      721 agcaggcagc agcagcagca gtagcagcag cagtagcagt gatgactcag aggaagagaa
      781 gaaggcagct gcacctctca agaagactgc acctaaaaag caagtcgtgg ccaaggcacc
      841 agtaaaagta actgctgccc ccacccaaaa gagttctagc agtgaggact cttccagtga
      901 agaggaagag gaacagaaaa aacccatgaa gaaaaaagca ggtccctaca gttcagttcc
      961 accaccttct gtttctttat ccaaaaagtc cgtgggagcc cagtctccaa agaaagcggc
     1021 cgcgcagaca cagcctgcag acagcagtgc agacagcagc gaggagtctg attcaagttc
     1081 tgaggaagag aagaaaactc cagctaagac agtcgtctcc aagacacccg ccaaaccagc
     1141 tccagtgaag aaaaaggccg agagctcttc agacagctca gattctgaca gttctgagga
     1201 tgaagctcct gccaagccag tcagtgccac caagagtccc ttaagcaagc cagctgtcac
     1261 tcctaagccg cctgctgcaa aggcagtggc aactcctaag cagcctgcgg gcagtggcca
     1321 gaaacctcag agcagaaagg ctgacagcag ctccagcgag gaggagagca gctccagtga
     1381 ggaagaggcc accaagaaaa gtgtgacaac ccctaaggcc agggtgaccg ccaaagcagc
     1441 accctctcta cctgccaaac aggctcctcg ggctggtgga gacagcagct ccgactcaga
     1501 gagttccagc agtgaggagg agaagaagac gccgcctaaa ccccccgcta agaagaaggc
     1561 agcaggtgca gccgttccca aacccacccc tgtgaagaaa gcagcagccg agagcagcag
     1621 cagcagcagc tcctccgaag attccagtga agaagagaaa aagaagccca agagcaaagc
     1681 tactcccaaa ccacaggcag gaaaggccaa tggcgttcca gcttctcaga acggaaaagc
     1741 aggcaaggaa agtgaggagg aagaggaaga cacagaacag aacaaaaagg cagccgggac
     1801 caagccaggt tcaggcaaga aacggaagca caatgagaca gcagatgaag cagcaactcc
     1861 tcaatctaag aaagttaagc tgcagacccc taatacgttt ccaaaaagga agaagggaga
     1921 gaaaagggca tcttcccctt tccgaagggt cagggaggag gagattgagg tggactctcg
     1981 agtagcagac aattccttcg atgccaagcg aggtgcagct ggagactggg gtgagcgagc
     2041 caatcaggtt ctgaagttca ccaaaggaaa gtccttccgg cacgaaaaaa caaagaagaa
     2101 gcgaggcagc taccggggag gctccatctc tgtccaggtc aattccgtca agtttgacag
     2161 cgagtgacct gtgtcatctt tagcaaagga agggtgactt tgggaggctg gcactcacct
     2221 ccaatggacc cagaaactca gtgttattag gagagagttg tggcacggac agtttgaagc
     2281 aggttctttg acactgcagt ctatagtcct tccatgctcc tgcttctgga caggtttgtt
     2341 tttgagcgtt gattgtcaaa gacaaaaagt ttttttgttt gttttgtttt attttttaag
     2401 aaatccattt ggttgtcagc tgccttcctg ttctgttggt cttcatactg agaaattgta
     2461 tattttatat taaatcatgt catacagatt tttgttgtga ttttcagaga tgagttccac
     2521 agattaaagt ctttgcctaa ggcaatgcac agagtcacat ggaggattct gtttatgtga
     2581 gtgcgcagac ccacatttga tcccacccct caaagccccg gtgggccctg acataagtct
     2641 tgtgatgttt gactgctaag catgccctgt gctcatcttc atccattggg cctgacaccg
     2701 aagcttcccg aagccggcgt ggatctgcca actttgggga taaaattgca gttcttggta
     2761 caatttccta ctgaactgac aggcaggatt ctcgatgtga gtgcgatgca acggtttttg
     2821 ttttgttctc agtagctatt agtgctacgt gtttacagtg tgttctagtt ttaatttcga
     2881 agtaagcttt tctgacactg agaggcattt gcaacaactt gactcttacc gctgttgtat
     2941 ataagctcat gaatatattt gattcttgtt aacatcatca agagcagaat ggtaaactcc
     3001 tgcatggttg aggcactggt caaggaagtg gagatgacct acctgagcct ctgggtgaag
     3061 taggtacggt ggatagatcc tgggcacctg cagtgaggag caggcgaagg acagtgaggc
     3121 tgggagaggt ctgggcagga ccgttctgtc tggatccctc ccctcaaagg gatcacatgg
     3181 gagtgattat gtcttattta agttggtccc ctggattgat tattggtacc ttaactatat
     3241 gatgttactg atacaggcta accagggggg ggctgggagg catatctggg tgatagtggc
     3301 gcttacctac cattcaagga cagagtgtga tctccatcaa ggcaggaagt gaatgagcag
     3361 agatccctgg gccaagggag taaattataa agccgtaaga tttgaccatt ggcagagctc
     3421 agccagagtg agggaaggga gaagagcacc ctggctaacc tggtgagaac agacacggag
     3481 cctccctggt ttggtttcca tggtcacctg gtaacctgct aaaagtgggt gcctgtggca
     3541 gctccttgag gaagtctgca tggtcaaagt tctgtgtctt actacaaaac aataaaatgg
     3601 atggtccctg
//
