LOCUS       NM_001395573            4575 bp    mRNA    linear   ROD 01-APR-2024
DEFINITION  Rattus norvegicus nucleolar protein 8 (Nol8), transcript variant 1,
            mRNA.
ACCESSION   NM_001395573 XM_006253689
VERSION     NM_001395573.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 4575)
  AUTHORS   Baltz,A.G., Munschauer,M., Schwanhausser,B., Vasile,A.,
            Murakawa,Y., Schueler,M., Youngs,N., Penfold-Brown,D., Drew,K.,
            Milek,M., Wyler,E., Bonneau,R., Selbach,M., Dieterich,C. and
            Landthaler,M.
  TITLE     The mRNA-bound proteome and its global occupancy profile on
            protein-coding transcripts
  JOURNAL   Mol Cell 46 (5), 674-690 (2012)
   PUBMED   22681889
REFERENCE   2  (bases 1 to 4575)
  AUTHORS   Castello,A., Fischer,B., Eichelbaum,K., Horos,R., Beckmann,B.M.,
            Strein,C., Davey,N.E., Humphreys,D.T., Preiss,T., Steinmetz,L.M.,
            Krijgsveld,J. and Hentze,M.W.
  TITLE     Insights into RNA biology from an atlas of mammalian mRNA-binding
            proteins
  JOURNAL   Cell 149 (6), 1393-1406 (2012)
   PUBMED   22658674
REFERENCE   3  (bases 1 to 4575)
  AUTHORS   Tarantino,C., Paolella,G., Cozzuto,L., Minopoli,G., Pastore,L.,
            Parisi,S. and Russo,T.
  TITLE     miRNA 34a, 100, and 137 modulate differentiation of mouse embryonic
            stem cells
  JOURNAL   FASEB J 24 (9), 3255-3263 (2010)
   PUBMED   20439489
REFERENCE   4  (bases 1 to 4575)
  AUTHORS   Sekiguchi,T., Hayano,T., Yanagida,M., Takahashi,N. and Nishimoto,T.
  TITLE     NOP132 is required for proper nucleolus localization of DEAD-box
            RNA helicase DDX47
  JOURNAL   Nucleic Acids Res 34 (16), 4593-4608 (2006)
   PUBMED   16963496
REFERENCE   5  (bases 1 to 4575)
  AUTHORS   Jinawath,N., Furukawa,Y. and Nakamura,Y.
  TITLE     Identification of NOL8, a nucleolar protein containing an RNA
            recognition motif (RRM), which was overexpressed in diffuse-type
            gastric cancer
  JOURNAL   Cancer Sci 95 (5), 430-435 (2004)
   PUBMED   15132771
REFERENCE   6  (bases 1 to 4575)
  AUTHORS   Sekiguchi,T., Todaka,Y., Wang,Y., Hirose,E., Nakashima,N. and
            Nishimoto,T.
  TITLE     A novel human nucleolar protein, Nop132, binds to the G proteins,
            RRAG A/C/D
  JOURNAL   J Biol Chem 279 (9), 8343-8350 (2004)
   PUBMED   14660641
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000017.1.
            
            On Jul 20, 2021 this sequence version replaced XM_006253689.4.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            RNAseq introns :: partial sample support SAMEA5760386, SAMEA5760389
                              [ECO:0000350]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            inferred exon combination :: based on alignments, homology
            RefSeq Select criteria    :: based on conservation
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-599               JAXUCZ010000017.1  15219604-15220202   c
            600-755             JAXUCZ010000017.1  15218821-15218976   c
            756-818             JAXUCZ010000017.1  15218106-15218168   c
            819-897             JAXUCZ010000017.1  15216671-15216749   c
            898-1033            JAXUCZ010000017.1  15215597-15215732   c
            1034-1102           JAXUCZ010000017.1  15214279-15214347   c
            1103-2881           JAXUCZ010000017.1  15211539-15213317   c
            2882-2995           JAXUCZ010000017.1  15210278-15210391   c
            2996-3118           JAXUCZ010000017.1  15209485-15209607   c
            3119-3209           JAXUCZ010000017.1  15209148-15209238   c
            3210-3345           JAXUCZ010000017.1  15207072-15207207   c
            3346-3423           JAXUCZ010000017.1  15204995-15205072   c
            3424-3695           JAXUCZ010000017.1  15201920-15202191   c
            3696-3822           JAXUCZ010000017.1  15200434-15200560   c
            3823-3890           JAXUCZ010000017.1  15199536-15199603   c
            3891-3970           JAXUCZ010000017.1  15199116-15199195   c
            3971-4575           JAXUCZ010000017.1  15196881-15197485   c
FEATURES             Location/Qualifiers
     source          1..4575
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="17"
                     /map="17p14"
     gene            1..4575
                     /gene="Nol8"
                     /note="nucleolar protein 8"
                     /db_xref="GeneID:361221"
                     /db_xref="RGD:1309551"
     exon            1..599
                     /gene="Nol8"
                     /inference="alignment:Splign:2.1.0"
     CDS             563..4021
                     /gene="Nol8"
                     /note="isoform 1 is encoded by transcript variant 1"
                     /codon_start=1
                     /product="nucleolar protein 8 isoform 1"
                     /protein_id="NP_001382502.1"
                     /db_xref="GeneID:361221"
                     /db_xref="RGD:1309551"
                     /translation="MERPLENFSSNLDRCPTFLKANREMKRLFVGGLGQGISETDLQS
                     QLSRFGEVSDVEIITRRDDQGNSQKVFAYVNIQITESDLKKCMSILNKTKWKGGTLQI
                     QLAKESFLHRLAQEREEAKAKKEKSTTGNTSLLEKMGGMDFHMKAVPGTAVPGHKNWV
                     VSKFGRVLPVLHLKNEHKQKIMKYDPSKYCHNIKKIPENLTETIPITDLTWELEGGND
                     PMSKKRRGEFSDFLPQKVKKVQKSIDPMECKVSDTGLRTNQVLERNKSAQPMTIHGTA
                     PSTVTPSKPLLVSSSGTQRPKHVVFHTSDFEIILNKSSMSDDDIDSEDELKMMIAEEE
                     NREKPGHPSVSESEHDTFEVVRDNFKSHVHKLPSSASLGNNHDYDSSDTDEIIAMKSI
                     GKVKNSTEFSQPERAISQRSSFQKIEPSNDCVKVQGTKSNKESAPCHGIKFVNPKFPP
                     DSNSSDSEESEEDEEYKILMKNCPRVSLTLADLEQMAGSHQKFSGKDTETNGPQNVSH
                     CKFDTTSKSSKTSGDLYNGRQCILPEEIVASLLEEENSYSKQKSEENILKPKFQAFKG
                     IGCLYAKESVDKTLKENTAFSTVSEHHSSLKQEDHSRSFMENGFKCVNGSSSKLTSCQ
                     PSKKVNDPNHIQPPKKQNQNSTSFDKGSINPLPCSLPLKAKTSLNLSTESHKIDSDGD
                     TCHWPENRKALEKERTNLSNFTSLEKPPKVSPRKDPQKSTASFSLSVSNASCITAKDK
                     HAEDNQKRLAALAAWQNAREVQKKLVHSALANLDGRPENRKTHIVFASDNESETEETS
                     THEQSCPEKELVKESVRKASGKLFDSSDDEESDSKEDSTRFSIKPQFEGRAGQKLMDL
                     QSHFGSDERFRMDSRFLESDSEDEQKELNENTVDEDELAAEKKKTLSVVQSVLNISVN
                     NPTSKGSVAAKKFKDIVHYDPTKHDHAIYERKQEDKEKESKAKRKKKKEEAEKLPEVS
                     QDMYYNIATDLKEIFQSMKNTDEKEEDTSRNEAYAREGAGEIRNAETLTCGSEQTAGF
                     TFSFFDSATKDVKDDTYRVEPVRRGKTVCQNDPRFQDSSSEEEDVTEEADHRKTSLGE
                     AVPEKETIRFFFFSENDDRLRGSDLFWSGAGGGISRSSWEARTSSLLLDCRKKHKEAK
                     RKVKTK"
     exon            600..755
                     /gene="Nol8"
                     /inference="alignment:Splign:2.1.0"
     exon            756..818
                     /gene="Nol8"
                     /inference="alignment:Splign:2.1.0"
     exon            819..897
                     /gene="Nol8"
                     /inference="alignment:Splign:2.1.0"
     exon            898..1033
                     /gene="Nol8"
                     /inference="alignment:Splign:2.1.0"
     exon            1034..1102
                     /gene="Nol8"
                     /inference="alignment:Splign:2.1.0"
     exon            1103..2881
                     /gene="Nol8"
                     /inference="alignment:Splign:2.1.0"
     exon            2882..2995
                     /gene="Nol8"
                     /inference="alignment:Splign:2.1.0"
     exon            2996..3118
                     /gene="Nol8"
                     /inference="alignment:Splign:2.1.0"
     exon            3119..3209
                     /gene="Nol8"
                     /inference="alignment:Splign:2.1.0"
     exon            3210..3345
                     /gene="Nol8"
                     /inference="alignment:Splign:2.1.0"
     exon            3346..3423
                     /gene="Nol8"
                     /inference="alignment:Splign:2.1.0"
     exon            3424..3695
                     /gene="Nol8"
                     /inference="alignment:Splign:2.1.0"
     exon            3696..3822
                     /gene="Nol8"
                     /inference="alignment:Splign:2.1.0"
     exon            3823..3890
                     /gene="Nol8"
                     /inference="alignment:Splign:2.1.0"
     exon            3891..3970
                     /gene="Nol8"
                     /inference="alignment:Splign:2.1.0"
     exon            3971..4575
                     /gene="Nol8"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 caacttgtcc cggaaatcag gaatcatgcg gcggagagtc ttttctgtag gaagttttct
       61 gtaggaatta tggatttttt taacccctct ggaaacttta caacgtggag gagaacaaac
      121 agaacgttcg tgaaaaagaa ggcagacgaa atgaggagcc ctctggaact gcgtgataac
      181 ggaaccttag gagatggggt tagaaaccct gtaggaagga aaagaaaatg cacccgcccg
      241 cacgtgttat tagacgttag gggctactct gcgcttgagc tgaggagcaa gcgtcttgag
      301 gagagtgttt gcgcgtgaga agtgctggac tgttgctcct agcctctcct ctccttcctt
      361 ggggtttctc ggagggagaa ggcggggttg gaaggatggg gcggcggcta ccaagaagtg
      421 gtacactgta ggtctttccc agactgcagg tctttgcttt ggggtcctgc cgccgccgtc
      481 ttgtgatctc gcttggaagg agtcagccag cttttgagga aggtttgaat gagagctgag
      541 cacctgccga gggcttaacg agatggagag acccctcgaa aacttttcca gcaaccttga
      601 tagatgccca acattcctga aagccaacag agaaatgaag cgcctctttg tgggtggact
      661 tgggcagggc atttctgaga cagacctaca aagtcagttg agcagatttg gagaagtttc
      721 tgacgtggag atcatcactc ggagagatga ccaaggaaat tcccagaaag tctttgcata
      781 tgttaacatc caaataacag aatcggacct gaaaaaatgt atgtctatct taaacaaaac
      841 aaaatggaaa ggtggaacac tacaaattca gctagcaaaa gaaagctttt tacacagatt
      901 ggcccaagaa agagaagaag caaaagcaaa gaaagaaaag tcaaccacag gcaatacctc
      961 cttattggaa aagatgggag gaatggattt ccatatgaag gctgtgcctg gaacagcggt
     1021 accaggacat aaaaattggg ttgtgagtaa atttggaaga gtcttacctg ttcttcacct
     1081 taagaatgaa cataaacaga aaattatgaa atatgatcca tcaaaatact gccacaatat
     1141 aaaaaagata ccagagaatt tgacagaaac cattcccata actgacctca cttgggaatt
     1201 ggaaggaggc aatgacccta tgagcaagaa acgtcgagga gagttttctg actttcttcc
     1261 tcaaaaggtc aagaaagtgc agaagagcat tgatcccatg gagtgcaagg tttctgatac
     1321 tggtctaagg actaatcagg tattggagag gaacaaatca gcacagccta tgactataca
     1381 cggcacagct ccaagtactg ttactccttc caaaccactc cttgtatcca gttctggtac
     1441 tcagagacct aaacatgtag tttttcatac ttctgacttt gaaattatct tgaataaaag
     1501 tagcatgtct gatgatgaca ttgactcaga agatgaattg aaaatgatga ttgctgaaga
     1561 ggaaaacaga gagaaacctg ggcatccctc agtcagtgag tctgaacatg acacttttga
     1621 agttgttagg gataatttca aatcacacgt tcataaactt ccttcttcag ctagtttagg
     1681 aaataaccat gactatgact caagtgacac agatgaaatt attgcaatga aaagcattgg
     1741 taaggtcaaa aacagtacag aattttcaca accagaaagg gctataagcc agagaagttc
     1801 ttttcaaaag atagaacctt ctaatgactg tgtaaaagta caaggaacta aaagcaacaa
     1861 agaatcagcc ccgtgtcatg gaataaagtt tgtaaatccc aaatttccac ctgactcgaa
     1921 tagcagtgac agtgaagagt ccgaggaaga tgaagaatat aaaatcttga tgaaaaactg
     1981 tccccgtgtg agtctcactc tggctgactt ggagcagatg gctggcagtc atcagaagtt
     2041 ttcaggaaaa gatacagaga ctaatggtcc acaaaatgtc agtcactgca aatttgacac
     2101 aacctccaag agttccaaga cttctggtga cttgtacaat ggccgacagt gcattcttcc
     2161 tgaggagatt gtggcctccc ttttagagga agagaacagt tacagcaaac aaaaatcaga
     2221 ggaaaatatc ttaaagccaa aattccaggc cttcaaggga ataggctgtc tctatgcaaa
     2281 ggagtcagtg gacaaaactt tgaaagagaa tactgccttt agtactgtca gtgagcatca
     2341 cagttccttg aaacaggaag atcacagtag aagttttatg gaaaatggat tcaagtgtgt
     2401 taatggctca tcaagcaaac tgacttcatg ccaaccttca aagaaggtga acgacccaaa
     2461 ccacattcag cctccaaaaa aacagaacca gaactctacg agttttgaca agggaagtat
     2521 aaatcctctg ccatgttcat tgccgttaaa agctaaaaca tccctaaatc ttagcacaga
     2581 gagtcacaag atagactctg atggagacac ttgccactgg cctgaaaata gaaaagcttt
     2641 agagaaagag aggactaatt taagcaactt cacatctctt gagaaaccac caaaggtatc
     2701 tcccaggaaa gaccctcaga aaagcacagc tagtttctca ctttctgtta gtaatgcatc
     2761 ttgtataact gctaaggata aacatgctga agataaccag aagcgattgg cagccttggc
     2821 agcatggcag aacgccagag aagtgcagaa gaaactggtg cacagtgcat tggcaaattt
     2881 ggatggtcgt ccagagaaca gaaaaacaca tattgtcttt gcttctgata atgaaagtga
     2941 aacggaagag acgtccactc atgagcaaag ctgtccagaa aaggagctgg tgaaagagtc
     3001 tgtgaggaaa gcatctggga agctgtttga cagcagtgat gatgaagaat cagattccaa
     3061 ggaggacagc accaggttca gcattaaacc tcagtttgag ggaagagctg gccagaagct
     3121 tatggatctg cagtctcatt ttggaagtga tgagagattc cgcatggact ctagattttt
     3181 agagagtgac agtgaagatg aacagaaaga gttaaatgaa aatacagtgg acgaagacga
     3241 gcttgctgca gaaaaaaaga aaaccctgag tgttgtgcaa agtgttctga acatcagtgt
     3301 aaacaaccct accagcaaag gatcagtggc tgctaagaaa tttaaggaca tcgtacatta
     3361 tgacccaaca aagcatgacc atgccattta cgaaagaaaa caagaagata aagaaaaaga
     3421 aagtaaggca aaacggaaga agaaaaagga agaagctgaa aagctgcctg aggtatccca
     3481 agacatgtat tataacattg ctacagattt gaaagaaata ttccaaagta tgaaaaacac
     3541 agatgaaaag gaagaagaca cgtccaggaa tgaggcttat gctagagagg gagctgggga
     3601 aatcaggaac gctgagacac tgacatgtgg gtccgagcag accgctggct ttacattctc
     3661 tttttttgat tctgccacca aagatgtaaa ggatgacacc tatagagttg aaccagtgag
     3721 acgtgggaag acagtctgtc agaacgatcc ccggttccaa gacagtagtt cagaagaaga
     3781 ggacgttact gaagaagcag accacagaaa gaccagcctt ggagaagcgg ttcctgagaa
     3841 agagaccatt aggtttttct ttttctctga gaatgatgac agacttcgtg gttctgactt
     3901 attctggagt ggtgcgggag gtggtattag cagaagttcg tgggaagccc gaacaagtag
     3961 tctccttttg gattgtcgga agaaacataa agaagccaag aggaaggtga aaacaaagta
     4021 accattgtca gctttgatgg gcactgaacg tgcagaccac agacagtaac ccaggaagga
     4081 ctgaacgtgc agaccaccag acagtaaccc aggaaggcgt tcactgacaa agaagcagtt
     4141 tcatagtaga aacgtattca aagcctggat aatgtatcat tctgatgact atttctgtgg
     4201 atatctgtat tccctccttg gtgactgtcc caaaattaac tgagccattt agcctcagca
     4261 ctttagaagg ggaagtgcgt ggatcatttg agcctggagt tttatatcac actcagcaac
     4321 acagcaatac ccacttcaga acaacagcca ctcttgttct ccactctgaa gcactagagg
     4381 ttatctcttg acaggaggct acacaaagcc ctgtttaata aatggtttga tgtacttgct
     4441 taaatatttc tgactatact atttatcttt ttaaactcga ctacaaatta actttgagtt
     4501 ctgtacttac agatgtaagt ttctgatgta atttctaaag acaaaataga actttttaaa
     4561 aaatggttca gaata
//
