LOCUS       NM_001012747             960 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus nucleolar protein 12 (Nol12), mRNA.
ACCESSION   NM_001012747 XM_343285
VERSION     NM_001012747.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 960)
  AUTHORS   Henras,A.K., Plisson-Chastang,C., O'Donohue,M.F., Chakraborty,A.
            and Gleizes,P.E.
  TITLE     An overview of pre-ribosomal RNA processing in eukaryotes
  JOURNAL   Wiley Interdiscip Rev RNA 6 (2), 225-242 (2015)
   PUBMED   25346433
  REMARK    Review article
REFERENCE   2  (bases 1 to 960)
  AUTHORS   Sloan,K.E., Mattijssen,S., Lebaron,S., Tollervey,D., Pruijn,G.J.
            and Watkins,N.J.
  TITLE     Both endonucleolytic and exonucleolytic cleavage mediate ITS1
            removal during human ribosomal RNA processing
  JOURNAL   J Cell Biol 200 (5), 577-588 (2013)
   PUBMED   23439679
REFERENCE   3  (bases 1 to 960)
  AUTHORS   Baltz,A.G., Munschauer,M., Schwanhausser,B., Vasile,A.,
            Murakawa,Y., Schueler,M., Youngs,N., Penfold-Brown,D., Drew,K.,
            Milek,M., Wyler,E., Bonneau,R., Selbach,M., Dieterich,C. and
            Landthaler,M.
  TITLE     The mRNA-bound proteome and its global occupancy profile on
            protein-coding transcripts
  JOURNAL   Mol Cell 46 (5), 674-690 (2012)
   PUBMED   22681889
REFERENCE   4  (bases 1 to 960)
  AUTHORS   Castello,A., Fischer,B., Eichelbaum,K., Horos,R., Beckmann,B.M.,
            Strein,C., Davey,N.E., Humphreys,D.T., Preiss,T., Steinmetz,L.M.,
            Krijgsveld,J. and Hentze,M.W.
  TITLE     Insights into RNA biology from an atlas of mammalian mRNA-binding
            proteins
  JOURNAL   Cell 149 (6), 1393-1406 (2012)
   PUBMED   22658674
REFERENCE   5  (bases 1 to 960)
  AUTHORS   Fujiwara,T., Suzuki,S., Kanno,M., Sugiyama,H., Takahashi,H. and
            Tanaka,J.
  TITLE     Mapping a nucleolar targeting sequence of an RNA binding nucleolar
            protein, Nop25
  JOURNAL   Exp Cell Res 312 (10), 1703-1712 (2006)
   PUBMED   16515785
  REMARK    GeneRIF: These data suggest that the nucleolar targeting sequence
            might play an important role in the binding of Nop25 to RNA
            molecules and that the RNA binding of Nop25 might be essential for
            the nucleolar localization of Nop25.
REFERENCE   6  (bases 1 to 960)
  AUTHORS   Suzuki,S., Kanno,M., Fujiwara,T., Sugiyama,H., Yokoyama,A.,
            Takahashi,H. and Tanaka,J.
  TITLE     Molecular cloning and characterization of Nop25, a novel nucleolar
            RNA binding protein, highly conserved in vertebrate species
  JOURNAL   Exp Cell Res 312 (7), 1031-1041 (2006)
   PUBMED   16430885
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC103643.1.
            
            On Sep 18, 2005 this sequence version replaced NM_001012747.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC103643.1, AY917132.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..960
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="7"
                     /map="7q34"
     gene            1..960
                     /gene="Nol12"
                     /gene_synonym="Nop25; RGD1305327"
                     /note="nucleolar protein 12"
                     /db_xref="GeneID:362955"
                     /db_xref="RGD:1305327"
     exon            1..105
                     /gene="Nol12"
                     /gene_synonym="Nop25; RGD1305327"
                     /inference="alignment:Splign:2.1.0"
     CDS             23..673
                     /gene="Nol12"
                     /gene_synonym="Nop25; RGD1305327"
                     /note="nucleolar protein, 25 kDa; 25 kDa nucleolar
                     protein"
                     /codon_start=1
                     /product="nucleolar protein 12"
                     /protein_id="NP_001012765.1"
                     /db_xref="GeneID:362955"
                     /db_xref="RGD:1305327"
                     /translation="MGRNKKKKRDGDDRRPRLILNFDEEKRREYLTGFHKRKVERKKA
                     AIEEIKQRLKQEQKKLREERHQEYLKMLAEREEALEEADELERLVTAKTESVQYDHPN
                     HTVTVTTVSDLDLSGARLLGLPLPEQGDQDGSQEEEVSSMEKPTKALPKKSKDPLLSQ
                     RISSLTATLHAHSRKKVKRKHPRRAQDSTKKPPSATRTSKTQRRRRMTGKARHNGE"
     exon            106..211
                     /gene="Nol12"
                     /gene_synonym="Nop25; RGD1305327"
                     /inference="alignment:Splign:2.1.0"
     exon            212..260
                     /gene="Nol12"
                     /gene_synonym="Nop25; RGD1305327"
                     /inference="alignment:Splign:2.1.0"
     exon            261..403
                     /gene="Nol12"
                     /gene_synonym="Nop25; RGD1305327"
                     /inference="alignment:Splign:2.1.0"
     exon            404..504
                     /gene="Nol12"
                     /gene_synonym="Nop25; RGD1305327"
                     /inference="alignment:Splign:2.1.0"
     exon            505..928
                     /gene="Nol12"
                     /gene_synonym="Nop25; RGD1305327"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cgctgccgga agcttcactg ttatgggccg caacaagaag aaaaaaagag atggagatga
       61 ccggcgtccc cggctcatcc tcaactttga tgaagagaag cggcgggaat acctgacagg
      121 cttccacaag cggaaggtag agcgcaagaa ggcagccatt gaagagataa agcagcggct
      181 taagcaagag cagaagaagc ttcgggaaga gcgccaccag gagtacctga agatgctggc
      241 agaaagagag gaggcactag aggaggccga tgagctggag cggctggtga cagcaaagac
      301 agagtcggtg cagtacgacc atcccaatca cacagtcact gtgaccaccg tcagtgacct
      361 ggacctctca ggggcccggc tgctaggtct acccctgcct gagcaagggg accaggatgg
      421 gtcccaggag gaggaggtgt catccatgga aaagccaaca aaagccttgc ccaagaagtc
      481 caaggatccc ctgctctctc agcgcatctc ctccctcaca gctacactgc atgcacacag
      541 tcggaagaag gtcaagagga aacaccctcg gcgggcgcag gactccacca agaaacctcc
      601 aagtgccact cgtaccagca agacccagcg ccgccgtcgg atgactggaa aagccaggca
      661 caacggggag tgagccctca agcttgtggg tccccagcct gagtccttgg ctgcccctat
      721 aacccagcta caccaagggt cacctgcagc ctgagcctga aaatcaggac tttgccagcc
      781 tggggtcatc cttgctttga accacctggg gtttgagccc agaagaaacg ggcttctgag
      841 aaccccgggt tcccggggcc tgtaggacag tgttgtggct tgtttgcaag tgtacgttca
      901 cctgggactg aacagacttt tgaaactcaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
//
