LOCUS       NM_001402074            2912 bp    mRNA    linear   ROD 30-MAR-2024
DEFINITION  Rattus norvegicus nucleolar protein 11 (Nol11), transcript variant
            1, mRNA.
ACCESSION   NM_001402074 XM_039087429
VERSION     NM_001402074.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2912)
  AUTHORS   Baltz,A.G., Munschauer,M., Schwanhausser,B., Vasile,A.,
            Murakawa,Y., Schueler,M., Youngs,N., Penfold-Brown,D., Drew,K.,
            Milek,M., Wyler,E., Bonneau,R., Selbach,M., Dieterich,C. and
            Landthaler,M.
  TITLE     The mRNA-bound proteome and its global occupancy profile on
            protein-coding transcripts
  JOURNAL   Mol Cell 46 (5), 674-690 (2012)
   PUBMED   22681889
REFERENCE   2  (bases 1 to 2912)
  AUTHORS   Castello,A., Fischer,B., Eichelbaum,K., Horos,R., Beckmann,B.M.,
            Strein,C., Davey,N.E., Humphreys,D.T., Preiss,T., Steinmetz,L.M.,
            Krijgsveld,J. and Hentze,M.W.
  TITLE     Insights into RNA biology from an atlas of mammalian mRNA-binding
            proteins
  JOURNAL   Cell 149 (6), 1393-1406 (2012)
   PUBMED   22658674
REFERENCE   3  (bases 1 to 2912)
  AUTHORS   Freed,E.F., Prieto,J.L., McCann,K.L., McStay,B. and Baserga,S.J.
  TITLE     NOL11, implicated in the pathogenesis of North American Indian
            childhood cirrhosis, is required for pre-rRNA transcription and
            processing
  JOURNAL   PLoS Genet 8 (8), e1002892 (2012)
   PUBMED   22916032
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000010.1.
            
            On Mar 5, 2022 this sequence version replaced XM_039087429.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26360172.1046686.1,
                                           SRR26360172.561886.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760386 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-186               JAXUCZ010000010.1  92641209-92641394   c
            187-300             JAXUCZ010000010.1  92639618-92639731   c
            301-357             JAXUCZ010000010.1  92639447-92639503   c
            358-506             JAXUCZ010000010.1  92637914-92638062   c
            507-564             JAXUCZ010000010.1  92636658-92636715   c
            565-709             JAXUCZ010000010.1  92634984-92635128   c
            710-898             JAXUCZ010000010.1  92634129-92634317   c
            899-975             JAXUCZ010000010.1  92633108-92633184   c
            976-1099            JAXUCZ010000010.1  92631927-92632050   c
            1100-1185           JAXUCZ010000010.1  92631532-92631617   c
            1186-1257           JAXUCZ010000010.1  92629951-92630022   c
            1258-1439           JAXUCZ010000010.1  92628939-92629120   c
            1440-1565           JAXUCZ010000010.1  92627161-92627286   c
            1566-1817           JAXUCZ010000010.1  92626753-92627004   c
            1818-1896           JAXUCZ010000010.1  92625769-92625847   c
            1897-1989           JAXUCZ010000010.1  92625238-92625330   c
            1990-2097           JAXUCZ010000010.1  92623070-92623177   c
            2098-2912           JAXUCZ010000010.1  92621482-92622296   c
FEATURES             Location/Qualifiers
     source          1..2912
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="10"
                     /map="10q32.1"
     gene            1..2912
                     /gene="Nol11"
                     /note="nucleolar protein 11"
                     /db_xref="GeneID:688885"
                     /db_xref="RGD:1584081"
     exon            1..186
                     /gene="Nol11"
                     /inference="alignment:Splign:2.1.0"
     CDS             46..2214
                     /gene="Nol11"
                     /note="isoform 1 is encoded by transcript variant 1"
                     /codon_start=1
                     /product="nucleolar protein 11 isoform 1"
                     /protein_id="NP_001389003.1"
                     /db_xref="GeneID:688885"
                     /db_xref="RGD:1584081"
                     /translation="MAALEEEFTLSTGVLGAGPEGFLGVEPSDKADQFLVTDRGRTVV
                     LYKVSDQKPLGSWSVKQGQTITCPAVCNFQTGEYIMVHDHKVLRIWNNEDVNLDKVFK
                     ATLSAEVHRIHSVQRTEPLVLFRRGAARGLEALLAEPQQNIEAVIPDEEVIEWSEVFM
                     LFKQPVLIFITENHGSYVAYVQLCKSHSLSKYILLLGKEEKSAKPNFTARVDGKFISL
                     VSLGSDGCVYETLVPIYSSDTENNQRLVRALMLKTVVSGSARNGSALTILDQDHIAVL
                     GPPLPASKECLSIWNIKFQTLQTSKELPQGTSGQLWYHGEILFMRHGKSLTVIPYKCE
                     ASSLASALGKLKHTQESGSHSVPHFVNWETCSEYELGSYSAKQTRTLRKKTETNLHPE
                     VPGVKELLSIIKKDSEKHIEVELRKFLAKSTPDFHTIIGDIVSGLLGRCKVEPSFYPR
                     NCLMQLIQTHVLSYSLCPDLMEIALEHTDVQMLQLCLQQFPDIPESTTCACLKLFLSI
                     GDDCLRDSNVSMESVFDYGDTTQDEKKEMEEQTEIVQNGFGPEDGGCSKDSQQLNKKP
                     GDTAQEPISFPVTLCPVAPKRAALLNAVLHSAYSEPFLLPHLKDIPAKHITLFLQYLY
                     FLYLKCTGSATMTLPGVSPPTVSQIMDWICLLLDANFTVVLMIPEAKRLLLNLYNFVK
                     SQISIYSELNKIEVSFRELQRLNQEKSSRGLYSIEVLELF"
     exon            187..300
                     /gene="Nol11"
                     /inference="alignment:Splign:2.1.0"
     exon            301..357
                     /gene="Nol11"
                     /inference="alignment:Splign:2.1.0"
     exon            358..506
                     /gene="Nol11"
                     /inference="alignment:Splign:2.1.0"
     exon            507..564
                     /gene="Nol11"
                     /inference="alignment:Splign:2.1.0"
     exon            565..709
                     /gene="Nol11"
                     /inference="alignment:Splign:2.1.0"
     exon            710..898
                     /gene="Nol11"
                     /inference="alignment:Splign:2.1.0"
     exon            899..975
                     /gene="Nol11"
                     /inference="alignment:Splign:2.1.0"
     exon            976..1099
                     /gene="Nol11"
                     /inference="alignment:Splign:2.1.0"
     exon            1100..1185
                     /gene="Nol11"
                     /inference="alignment:Splign:2.1.0"
     exon            1186..1257
                     /gene="Nol11"
                     /inference="alignment:Splign:2.1.0"
     exon            1258..1439
                     /gene="Nol11"
                     /inference="alignment:Splign:2.1.0"
     exon            1440..1565
                     /gene="Nol11"
                     /inference="alignment:Splign:2.1.0"
     exon            1566..1817
                     /gene="Nol11"
                     /inference="alignment:Splign:2.1.0"
     exon            1818..1896
                     /gene="Nol11"
                     /inference="alignment:Splign:2.1.0"
     exon            1897..1989
                     /gene="Nol11"
                     /inference="alignment:Splign:2.1.0"
     exon            1990..2097
                     /gene="Nol11"
                     /inference="alignment:Splign:2.1.0"
     exon            2098..2912
                     /gene="Nol11"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gcaaagccta ctgggaggca tgcacgggct gtaggccagc ccaaaatggc agccttggaa
       61 gaagaattca cgttgtctac tggagtctta ggcgccgggc ctgaaggatt cctaggtgta
      121 gagcccagtg acaaggccga ccagttccta gtgaccgaca gaggcaggac cgtcgtcctc
      181 tacaaggttt ctgaccagaa acccttgggc agctggtcgg tgaaacaagg ccagactata
      241 acatgtcctg ctgtgtgcaa ctttcagact ggagagtata ttatggtaca tgaccataag
      301 gttttgagaa tatggaataa tgaagacgta aacctggata aagtattcaa agctacactg
      361 tcagctgagg tccataggat ccactcagta caaagaacag aacccctggt gctgttccga
      421 agaggcgctg ctcgtgggtt agaggccttg cttgcagagc cacagcagaa cattgaagct
      481 gtcataccag atgaggaagt gatcgagtgg tcagaggttt tcatgttatt taagcaaccg
      541 gttttaattt ttattactga aaatcatggg agttatgttg cttatgtaca attgtgcaaa
      601 tcacacagct taagcaaata catactctta cttggaaaag aagaaaaatc tgctaaacca
      661 aattttactg cacgtgtgga tgggaaattc atctccctgg tgtcgctagg ctctgatggg
      721 tgtgtatatg aaaccttggt accaatatat tcaagtgaca cggaaaacaa tcagaggtta
      781 gttagagcat tgatgctcaa gacggttgtg tctggcagtg ctcgaaatgg ttctgccctc
      841 accatcctgg atcaagacca catagcagtc ctgggacctc cacttccagc ttctaaggaa
      901 tgcctctcca tatggaacat aaaatttcag acattacaga catcaaaaga gctgccacaa
      961 ggaaccagtg ggcaactctg gtatcatggg gaaatactat ttatgcgaca tgggaaaagt
     1021 ctaactgtga ttccatacaa gtgcgaagca tcatctctgg cgagcgctct tgggaagctc
     1081 aagcatactc aagagtcagg cagtcattcc gtgccccatt ttgtaaactg ggagacgtgt
     1141 tcagaatatg aacttgggtc ctacagtgca aagcagacaa gaactcttag aaaaaaaact
     1201 gaaacaaatt tacacccaga agttccagga gtcaaagaac ttttatcaat aataaagaaa
     1261 gattcagaaa agcacattga agtagaacta cgtaagtttt tggctaagtc gacacctgac
     1321 tttcatacta taattggaga catagtgtct ggacttctgg gaagatgtaa agtggaacca
     1381 tcgttttacc cccggaactg tctgatgcag ctcatccaga cacacgtgct ttcctacagc
     1441 ttatgccctg acttgatgga gattgcccta gagcacacag atgtgcagat gttacagctg
     1501 tgtctgcagc agttccctga cattcctgag tccaccacct gtgcttgctt aaaacttttc
     1561 ctgagcattg gtgatgactg tcttcgggac agtaatgtca gcatggagtc agtttttgat
     1621 tatggtgata ctacacaaga tgagaaaaag gaaatggaag agcaaactga aattgttcag
     1681 aatggcttcg gtcctgaaga tggtggctgc agtaaagata gtcagcagtt gaacaaaaag
     1741 cctggtgaca cagcacagga gcccatctcc ttccctgtga ccttgtgtcc tgtggcacca
     1801 aagcgagcag ctctgctaaa tgcagtcctt cattcagcat acagtgagcc cttcctcctg
     1861 ccgcacttga aggacatccc tgcgaagcat ataacgctgt ttctgcagta tttgtatttc
     1921 ctctatttga agtgcactgg cagtgctacc atgactctcc ctggagtaag ccctccaacc
     1981 gtgagccaga tcatggattg gatatgccta cttctagatg ctaattttac tgtcgtctta
     2041 atgataccag aagcaaaaag acttttgctt aatctttaca attttgtgaa atcgcagatc
     2101 tccatctact ccgagctcaa caagattgaa gtcagcttcc gggagctgca gaggttaaat
     2161 caggagaaga gcagtagagg actgtactcc atcgaagttc tggaactttt ctgacagcca
     2221 gagacagtct tactggctgt cctagaactg gatatataga ccaagctggc ctcaaactca
     2281 cagagatcca acccagagca ctgcgattaa aggtgtggcc accacacctg gcttaatgga
     2341 tttttttata tgaatgtacc tgttcatcca gaggagaaag ttttgtttgt atccatctca
     2401 gtgtccagag aggagtgtga gtctctgcac catcacatac caccattcct cagtgctacg
     2461 ggttccacag acatcacttc tgggttgcag acatcactgg aagaatgtta caaacttttt
     2521 aaacatggaa ttgagttgat tttaagtaaa cttatttgtg tactgataaa agtctagttt
     2581 cttaccgtgc attttgaata gtttttcttt caataaaata agcaagccat ctctgaagag
     2641 tggatctaaa acggatgagt gtcggtcgga agctattgca gtcatctgtc tcatggagaa
     2701 ctcaggaccc caagccaacg tagtgcgttc tgcctcgcca tttcttcatc tttcaccgtc
     2761 tgccatctct cctccctcag gggttgagaa attccccctt ccagcgtgat gtctcagaca
     2821 aactgtgaca aggatatggt aaagatcagt ttaaattata aaatcttatt accaagtaat
     2881 gaaaatgtct ctctttaaaa aaaaaaaaaa aa
//
